**Selected for 2026 Doody's Core Titles in Urology**
Designed for quick reference and efficient, accurate sign-outs, Uropathology, 2nd Edition, provides superbly illustrated, expert guidance in a time-saving format. This updated volume in the High-Yield Pathology series is highly templated for ease of use, featuring bulleted text, authoritative content, and high-quality images that comprehensively cover both non-neoplastic and neoplastic entities, making it easy to recognize the classic manifestations of urologic diseases and quickly confirm your diagnoses.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Inside front cover - p. iii 5. Copyright - p. iii 6. Dedication - p. iii 7. Contributors - p. iii 8. Preface - p. iii 9. Table of contents - p. iii 10. List of Illustrations - p. iii 11. List of Tables - p. iii 12. A: Nonneoplastic Disease of the Prostate - p. iii 13. Chapter 1: Anatomy and histology of the prostate - p. iii 14. Chapter 2: Seminal vesicle/ejaculatory duct - p. 6 15. Chapter 3: Cowper gland - p. 9 16. Chapter 4: Benign prostatic hyperplasia - p. 11 17. Chapter 5: Acute inflammation of the prostate - p. 14 18. Chapter 6: Chronic inflammation of the prostate - p. 16 19. Chapter 7: Nonspecific granulomatous prostatitis - p. 18 20. Chapter 8: Post-biopsy granuloma - p. 20 21. Chapter 9: Prostatic xanthoma - p. 21 22. Chapter 10: Granulomatous prostatitis of infectious etiology - p. 22 23. Chapter 11: Simple atrophy - p. 24 24. Chapter 12: Cystic atrophy - p. 25 25. Chapter 13: Postatrophy hyperplasia - p. 26 26. Chapter 14: Partial atrophy - p. 28 27. Chapter 15: Adenosis - p. 30 28. Chapter 16: Sclerosing adenosis - p. 32 29. Chapter 17: Clear cell cribriform hyperplasia - p. 35 30. Chapter 18: Hyperplasia of mesonephric remnants - p. 37 31. Chapter 19: Basal cell hyperplasia - p. 39 32. Chapter 20: Urothelial metaplasia - p. 42 33. Chapter 21: Squamous metaplasia - p. 43 34. Chapter 22: Mucin cell metaplasia - p. 44 35. Chapter 23: Neuroendocrine cells involving the prostate - p. 45 36. Chapter 24: Verumontanum mucosal gland hyperplasia - p. 47 37. Chapter 25: Prostatic infarct - p. 48 38. B: Neoplastic Disease of the Prostate - p. 50 39. Chapter 26: High-grade prostatic intraepithelial neoplasia (HGPIN) - p. 50 40. Chapter 27: Intraductal carcinoma of the prostate - p. 55 41. Chapter 28: Prostatic carcinoma, usual variant - p. 58 42. Chapter 29: Prostatic carcinoma, atrophic variant - p. 65 43. Chapter 30: Prostatic carcinoma, foamy gland variant - p. 67 44. Chapter 31: Prostatic carcinoma, pseudohyperplastic variant - p. 69 45. Chapter 32: Prostatic carcinoma, mucinous variant - p. 72 46. Chapter 33: Prostatic carcinoma, microcystic variant - p. 74 47. Chapter 34: Prostatic intraepithelial neoplasia (PIN)-like adenocarcinoma - p. 77 48. Chapter 35: Sarcomatoid carcinoma - p. 80 49. Chapter 36: Pleomorphic giant cell carcinoma of the prostate - p. 82 50. Chapter 37: Lymphoepithelioma-like carcinoma of the prostate - p. 84 51. Chapter 38: Prostate carcinoma with squamous differentiation - p. 85 52. Chapter 39: Ductal adenocarcinoma - p. 87 53. Chapter 40: Prostatic adenocarcinoma with neuroendocrine differentiation - p. 90 54. Chapter 41: Well-differentiated neuroendocrine tumor - p. 93 55. Chapter 42: Small cell carcinoma, prostate - p. 96 56. Chapter 43: Prostatic basal cell adenoma - p. 99 57. Chapter 44: Basal cell carcinoma of the prostate - p. 101 58. Chapter 45: Squamous neoplasms including squamous cell and adenosquamous carcinoma - p. 103 59. Chapter 46: Urothelial carcinoma - p. 104 60. Chapter 47: Prostatic stromal tumors of uncertain malignant potential - p. 107 61. Chapter 48: Prostatic stromal sarcoma - p. 110 62. Chapter 49: Atypical glands suspicious for prostatic carcinoma - p. 112 63. Chapter 50: High-grade prostatic intraepithelial neoplasia with adjacent atypical glands - p. 115 64. Chapter 51: Radiation-induced changes - p. 117 65. Chapter 52: Hormonal ablation-induced changes - p. 120 66. Chapter 53: Cryoablation therapy-induced changes - p. 123 67. Chapter 54: Immunohistochemical work-up of prostate carcinoma - p. 126 68. Chapter 55: Gleason grading of prostate carcinoma - p. 129 69. Chapter 56: Prostate cancer staging in radical prostatectomy - p. 133 70. Chapter 57: Genetics and genomics in prostate cancer - p. 137 71. Chapter 58: Work-up of “vanishing” cancer in radical prostatectomy - p. 139 72. Chapter 59: Nonprostatic adenocarcinoma involving the prostate - p. 140 73. C: Seminal Vesicles - p. 142 74. Chapter 60: Anatomy and histology of seminal vesicles - p. 142 75. Chapter 61: Amyloidosis - p. 146 76. Chapter 62: Seminal vesicle adenocarcinoma - p. 148 77. Chapter 63: Mixed epithelial and stromal tumor - p. 149 78. D: Nonneoplastic Disease of the Urinary Bladder - p. 151 79. Chapter 64: Anatomy and histology of the urinary bladder - p. 151 80. Chapter 65: von Brunn nests - p. 155 81. Chapter 66: Cystitis cystica et glandularis - p. 156 82. Chapter 67: Squamous metaplasia - p. 158 83. Chapter 68: Intestinal metaplasia - p. 160 84. Chapter 69: Nephrogenic metaplasia/adenoma - p. 162 85. Chapter 70: Polypoid and papillary cystitis - p. 165 86. Chapter 71: Follicular cystitis - p. 167 87. Chapter 72: Giant cell cystitis - p. 168 88. Chapter 73: Interstitial cystitis/painful bladder syndrome - p. 169 89. Chapter 74: Eosinophilic cystitis - p. 171 90. Chapter 75: Infectious cystitis - p. 173 91. Chapter 76: Malakoplakia - p. 177 92. Chapter 77: Granulomatous cystitis after BCG - p. 179 93. Chapter 78: Radiation cystitis - p. 181 94. Chapter 79: Chemotherapy-induced cystitis - p. 183 95. Chapter 80: Endometriosis of the bladder - p. 185 96. Chapter 81: Bladder endocervicosis - p. 188 97. Chapter 82: Bladder exstrophy - p. 191 98. Chapter 83: Urachal anomaly - p. 192 99. Chapter 84: Bladder diverticulum - p. 194 100. Chapter 85: Ectopic prostate tissue - p. 196 101. E: Neoplastic Disease of the Urinary Bladder - p. 198 102. Chapter 86: Urothelial proliferation of uncertain malignant potential - p. 198 103. Chapter 87: Reactive urothelial atypia - p. 201 104. Chapter 88: Urothelial atypia of unknown significance - p. 203 105. Chapter 89: Urothelial dysplasia - p. 204 106. Chapter 90: Urothelial carcinoma in situ - p. 206 107. Chapter 91: Urothelial papilloma - p. 208 108. Chapter 92: Inverted papilloma - p. 210 109. Chapter 93: Papillary urothelial neoplasm of low malignant potential - p. 213 110. Chapter 94: Low-grade papillary urothelial carcinoma - p. 215 111. Chapter 95: High-grade papillary urothelial carcinoma - p. 217 112. Chapter 96: Invasive urothelial carcinoma - p. 219 113. Chapter 97: Urothelial carcinoma with inverted growth pattern - p. 222 114. Chapter 98: Urothelial carcinoma with squamous differentiation - p. 224 115. Chapter 99: Urothelial carcinoma with villoglandular differentiation - p. 225 116. Chapter 100: Urothelial carcinoma, plasmacytoid variant - p. 227 117. Chapter 101: Urothelial carcinoma, nested variant - p. 230 118. Chapter 102: Urothelial carcinoma, micropapillary variant - p. 233 119. Chapter 103: Urothelial carcinoma, microcystic variant - p. 236 120. Chapter 104: Urothelial carcinoma, lymphoepithelioma-like carcinoma variant - p. 238 121. Chapter 105: Urothelial carcinoma, clear cell (glycogen-rich) variant - p. 240 122. Chapter 106: Lipid-rich urothelial carcinoma - p. 242 123. Chapter 107: Urothelial carcinoma, giant cell variant - p. 243 124. Chapter 108: Urothelial carcinoma with syncytiotrophoblastic giant cells - p. 245 125. Chapter 109: Urothelial carcinoma with rhabdoid differentiation - p. 248 126. Chapter 110: Urothelial carcinoma similar to giant cell tumor of bone - p. 250 127. Chapter 111: Undifferentiated urothelial carcinomas - p. 252 128. Chapter 112: Small cell carcinoma of the urinary bladder - p. 254 129. Chapter 113: Urothelial carcinoma with unusual stromal reactions - p. 256 130. Chapter 114: Urothelial carcinoma with sarcomatoid differentiation - p. 257 131. Chapter 115: Villous adenoma - p. 260 132. Chapter 116: Adenocarcinoma - p. 262 133. Chapter 117: Clear cell adenocarcinoma - p. 264 134. Chapter 118: Urachal adenocarcinoma - p. 266 135. Chapter 119: Squamous cell carcinoma - p. 268 136. Chapter 120: Paraganglioma - p. 270 137. Chapter 121: Staging of urothelial carcinoma of the urinary bladder and urethra - p. 272 138. Chapter 122: Molecular genomics of bladder cancer - p. 274 139. Chapter 123: Secondary spread of prostate carcinoma to the bladder - p. 278 140. Chapter 124: Secondary adenocarcinoma involving the bladder, other than prostatic carcinoma - p. 280 141. F: Nonneoplastic Disease of the Kidney - p. 283 142. Chapter 125: Anatomy of the kidney - p. 283 143. Chapter 126: Renal dysplasia - p. 287 144. Chapter 127: Localized cystic disease of the kidney - p. 289 145. Chapter 128: Autosomal recessive polycystic kidney disease - p. 290 146. Chapter 129: Autosomal dominant polycystic kidney disease - p. 292 147. Chapter 130: Medullary sponge kidney - p. 295 148. Chapter 131: Acquired cystic renal disease - p. 296 149. Chapter 132: Simple cortical cyst - p. 298 150. Chapter 133: Acute pyelonephritis - p. 299 151. Chapter 134: Chronic nonobstructive pyelonephritis - p. 301 152. Chapter 135: Chronic obstructive pyelonephritis - p. 303 153. Chapter 136: Xanthogranulomatous pyelonephritis - p. 305 154. Chapter 137: Renal papillary necrosis - p. 307 155. Chapter 138: Benign nephrosclerosis - p. 308 156. Chapter 139: Malignant nephrosclerosis - p. 311 157. Chapter 140: Acute kidney injury (acute tubular necrosis) - p. 313 158. Chapter 141: Acute interstitial nephritis - p. 315 159. Chapter 142: Infectious interstitial nephritis - p. 317 160. G: Neoplastic Disease of the Kidney - p. 319 161. Chapter 143: Papillary adenoma - p. 319 162. Chapter 144: Renal oncocytoma - p. 322 163. Chapter 145: Clear cell renal cell carcinoma - p. 325 164. Chapter 146: Multilocular cystic renal neoplasm of low malignant potential - p. 328 165. Chapter 147: Papillary renal cell carcinoma - p. 330 166. Chapter 148: Chromophobe renal cell carcinoma - p. 335 167. Chapter 149: Fumarate hydratase-deficient renal cell carcinoma, including hereditary leiomyomatosis and renal cell carcinoma syndrome - p. 337 168. Chapter 150: Collecting duct carcinoma - p. 339 169. Chapter 151: Renal medullary carcinoma - p. 342 170. Chapter 152: Mit family translocation renal cell carcinoma - p. 344 171. Chapter 153: Succinate dehydrogenase-deficient renal cell carcinoma - p. 346 172. Chapter 154: Mucinous tubular and spindle cell carcinoma - p. 348 173. Chapter 155: Tubulocystic carcinoma - p. 350 174. Chapter 156: Acquired cystic kidney disease-associated renal cell carcinoma - p. 353 175. Chapter 157: Thyroid-like follicular renal cell carcinoma - p. 355 176. Chapter 158: Clear cell papillary renal cell carcinoma - p. 357 177. Chapter 159: Renal cell carcinoma with fibromyomatous stroma - p. 360 178. Chapter 160: Eosinophilic solid cystic renal cell carcinoma - p. 362 179. Chapter 161: Renal cell carcinoma with somatic mutations in TSC/mTORC1 genes - p. 364 180. Chapter 162: Renal cell carcinoma with sarcomatoid differentiation - p. 367 181. Chapter 163: Renal cell carcinoma, unclassified type - p. 370 182. Chapter 164: Grading system for renal cell carcinoma - p. 372 183. Chapter 165: Staging of renal cell carcinoma - p. 375 184. Chapter 166: Renal cell carcinoma in von Hippel-Lindau disease - p. 377 185. Chapter 167: Renal cell neoplasms in Birt-Hogg-Dubé (BHD) syndrome - p. 379 186. Chapter 168: Renal tumors in tuberous sclerosis complex (TSC) - p. 381 187. Chapter 169: Metanephric adenoma - p. 384 188. Chapter 170: Metanephric stromal tumor - p. 386 189. Chapter 171: Wilms tumor - p. 388 190. Chapter 172: Nephrogenic rests and nephroblastomatosis - p. 391 191. Chapter 173: Congenital mesoblastic nephroma (CMN) - p. 392 192. Chapter 174: Rhabdoid tumor of the kidney - p. 395 193. Chapter 175: Clear cell sarcoma of the kidney - p. 397 194. Chapter 176: Ossifying renal tumor of infancy - p. 399 195. Chapter 177: Renal angiomyolipoma - p. 401 196. Chapter 178: Epithelioid angiomyolipoma - p. 405 197. Chapter 179: Juxtaglomerular cell tumor - p. 408 198. Chapter 180: Renal medullary fibroma (renomedullary interstitial cell tumor) - p. 409 199. Chapter 181: Mixed epithelial and stromal tumor family - p. 411 200. Chapter 182: Primary renal synovial sarcoma - p. 413 201. Chapter 183: Renal carcinoid tumor - p. 415 202. H: Renal Pelvis and Ureter - p. 417 203. Chapter 184: Ureteropelvic junction obstruction - p. 417 204. Chapter 185: Idiopathic retroperitoneal fibrosis, including IgG4-related disease - p. 421 205. Chapter 186: Fibroepithelial polyp of the ureter and renal pelvis - p. 423 206. Chapter 187: Ureteral urothelial carcinoma and staging - p. 424 207. Chapter 188: Staging for pelvic urothelial carcinoma - p. 425 208. I: Nonneoplastic Disease of the Testis - p. 426 209. Chapter 189: Testis: Anatomy and histology - p. 426 210. Chapter 190: Cryptorchidism - p. 429 211. Chapter 191: Testiculosplenic fusion - p. 432 212. Chapter 192: Adrenal cortical rests - p. 434 213. Chapter 193: Spermatic cord torsion and testicular infarction - p. 436 214. Chapter 194: Testicular microlithiasis - p. 438 215. Chapter 195: Vasculitis - p. 440 216. Chapter 196: Male infertility workup - p. 442 217. Chapter 197: Maturation arrest - p. 444 218. Chapter 198: Hypospermatogenesis - p. 445 219. Chapter 199: Germ cell aplasia, sertoli cell-only syndrome - p. 447 220. Chapter 200: Excurrent duct obstruction - p. 449 221. Chapter 201: Pre-pubertal gonadotropin deficiency - p. 450 222. Chapter 202: Postpubertal gonadotrophin deficiency - p. 452 223. Chapter 203: Viral orchitis - p. 453 224. Chapter 204: Granulomatous orchiepididymitis - p. 454 225. Chapter 205: Nonspecific granulomatous orchitis - p. 456 226. Chapter 206: Androgen insensitivity syndrome - p. 458 227. Chapter 207: Klinefelter syndrome - p. 459 228. Chapter 208: Testicular tumor of the adrenogenital syndrome - p. 461 229. Chapter 209: Embryonic testicular regression (Vanishing testis syndrome) - p. 464 230. Chapter 210: Gonadal dysgenesis - p. 466 231. J: Neoplastic Disease of the Testis - p. 468 232. Chapter 211: Germ cell neoplasia in situ - p. 468 233. Chapter 212: Specific forms of intratubular germ cell neoplasia - p. 471 234. Chapter 213: Seminoma - p. 472 235. Chapter 214: Embryonal carcinoma - p. 476 236. Chapter 215: Postpubertal-type yolk sac tumor - p. 479 237. Chapter 216: Postpubertal-type teratoma - p. 482 238. Chapter 217: Mixed germ cell tumor - p. 484 239. Chapter 218: Teratoma with somatic-type malignancies - p. 486 240. Chapter 219: Choriocarcinoma - p. 488 241. Chapter 220: Non-choriocarcinomatous trophoblastic tumors - p. 490 242. Chapter 221: Regressed germ cell tumors - p. 491 243. Chapter 222: Spermatocytic tumor - p. 493 244. Chapter 223: Prepubertal-type teratoma, testicular carcinoid tumor - p. 495 245. Chapter 224: Teratoma, prepubertal-type, dermoid cyst - p. 497 246. Chapter 225: Prepubertal teratoma, epidermoid cyst - p. 499 247. Chapter 226: Yolk sac tumor, prepubertal type - p. 500 248. Chapter 227: Leydig cell tumor - p. 501 249. Chapter 228: Sertoli cell tumor - p. 504 250. Chapter 229: Sclerosing sertoli cell tumor - p. 507 251. Chapter 230: Large cell calcifying sertoli cell tumor - p. 509 252. Chapter 231: Adult granulosa cell tumor - p. 511 253. Chapter 232: Juvenile granulosa cell tumor - p. 513 254. Chapter 233: Fibrothecoma - p. 515 255. Chapter 234: Stromal tumor of the testis, mixed and unclassified type - p. 517 256. Chapter 235: Myoid gonadal stromal tumor - p. 519 257. Chapter 236: Gonadoblastoma - p. 521 258. Chapter 237: Testicular lymphoma - p. 523 259. Chapter 238: Ovarian epithelial-type testicular tumors - p. 525 260. Chapter 239: Tumors of the rete testis - p. 529 261. Chapter 240: Testicular cancer staging - p. 532 262. K: Spermatic Cord and Testicular Adnexa - p. 534 263. Chapter 241: Appendix testis - p. 534 264. Chapter 242: Appendix epididymis - p. 537 265. Chapter 243: Glandular inclusions in inguinal herniorrhaphy specimens - p. 538 266. Chapter 244: Hydrocele - p. 540 267. Chapter 245: Spermatocele - p. 542 268. Chapter 246: Vasitis nodosa - p. 544 269. Chapter 247: Sperm granuloma - p. 546 270. Chapter 248: Adenomatoid tumor - p. 548 271. Chapter 249: Fibrous pseudotumor - p. 550 272. Chapter 250: Paratesticular idiopathic smooth muscle hyperplasia - p. 552 273. Chapter 251: Papillary cystadenoma of the epididymis - p. 553 274. Chapter 252: Paratesticular lipoma - p. 554 275. Chapter 253: Paratesticular liposarcoma - p. 555 276. Chapter 254: Paratesticular rhabdomyosarcoma - p. 557 277. Chapter 255: Leiomyoma of the spermatic cord and testicular adnexa - p. 559 278. Chapter 256: Paratesticular leiomyosarcoma - p. 561 279. Chapter 257: Aggressive angiomyxoma of the male genital region - p. 562 280. Chapter 258: Cellular angiofibroma - p. 564 281. Chapter 259: Malignant mesothelioma, paratesticular - p. 566 282. Chapter 260: Epithelial tumors of the rete testis - p. 568 283. L: Disease of the Penis, Urethra, and Scrotum - p. 570 284. Chapter 261: Fibroepithelial polyp of the urethra - p. 570 285. Chapter 262: Urethral caruncle - p. 573 286. Chapter 263: Urethral diverticulum - p. 575 287. Chapter 264: Urethral stricture - p. 577 288. Chapter 265: Polypoid urethritis - p. 578 289. Chapter 266: Condyloma acuminatum - p. 579 290. Chapter 267: Prostatic-type urethral polyp - p. 581 291. Chapter 268: Urethral urothelial carcinoma associated with bladder urothelial carcinoma - p. 583 292. Chapter 269: Primary urethral carcinoma - p. 585 293. Chapter 270: Urethral adenocarcinoma - p. 587 294. Chapter 271: Clear cell adenocarcinoma of the urethra - p. 589 295. Chapter 272: Zoon balanitis - p. 591 296. Chapter 273: Lichen sclerosus et atrophicus (balanitis xerotica obliterans) - p. 592 297. Chapter 274: Pseudoepitheliomatous keratotic micaceous balanitis - p. 594 298. Chapter 275: Peyronie disease - p. 596 299. Chapter 276: Squamous hyperplasia of the penis - p. 597 300. Chapter 277: Penile intraepithelial neoplasia (PeIN) - p. 598 301. Chapter 278: Differentiated penile intraepithelial neoplasia - p. 600 302. Chapter 279: Squamous cell carcinoma of the penis, usual type - p. 602 303. Chapter 280: Basaloid squamous cell carcinoma - p. 604 304. Chapter 281: Squamous cell carcinoma, papillary-basaloid - p. 606 305. Chapter 282: Penile warty (condylomatous) carcinoma - p. 608 306. Chapter 283: Squamous cell carcinoma, warty-basaloid - p. 610 307. Chapter 284: Clear cell squamous cell carcinoma - p. 612 308. Chapter 285: Lymphoepithelioma-like carcinoma - p. 614 309. Chapter 286: Squamous cell carcinoma, verrucous - p. 615 310. Chapter 287: Squamous cell carcinoma, papillary - p. 617 311. Chapter 288: Squamous cell carcinoma, pseudohyperplastic variant - p. 619 312. Chapter 289: Squamous cell carcinoma, pseudoglandular - p. 621 313. Chapter 290: Squamous cell carcinoma, cuniculatum - p. 623 314. Chapter 291: Sarcomatoid (spindle cell) squamous cell carcinoma of the penis - p. 625 315. Chapter 292: Adenosquamous carcinoma of the penis - p. 627 316. Chapter 293: Mixed squamous cell carcinoma of the penis - p. 628 317. Chapter 294: Penile basal cell carcinoma - p. 630 318. Chapter 295: Extramammary Paget disease of the penis and scrotum - p. 631 319. Chapter 296: Merkel cell carcinoma of the genitourinary tract - p. 634 320. Chapter 297: Sclerosing lipogranuloma - p. 636 321. Chapter 298: Idiopathic scrotal calcinosis - p. 638 322. Chapter 299: Genital melanosis and lentiginosis - p. 640 323. Chapter 300: Mucosal melanoma of the genitourinary system - p. 641 324. Chapter 301: Staging for penile squamous cell carcinoma - p. 643 325. Chapter 302: Staging for urethral carcinoma - p. 644 326. M: Soft Tissue Tumors - p. 646 327. Chapter 303: Inflammatory myofibroblastic tumor of the bladder - p. 646 328. Chapter 304: Leiomyoma of the bladder - p. 649 329. Chapter 305: Leiomyosarcoma of the bladder - p. 650 330. Chapter 306: Solitary fibrous tumor - p. 652 331. Chapter 307: Gastrointestinal stromal tumor of the genitourinary tract - p. 654 332. Chapter 308: Lymphomas of the genitourinary organs - p. 656 333. Index - p. 659 334. Inside back cover - p. 659
**Selected for 2026 Doody's Core Titles in Urology**
Designed for quick reference and efficient, accurate sign-outs, Uropathology, 2nd Edition, provides superbly illustrated, expert guidance in a time-saving format. This updated volume in the High-Yield Pathology series is highly templated for ease of use, featuring bulleted text, authoritative content, and high-quality images that comprehensively cover both non-neoplastic and neoplastic entities, making it easy to recognize the classic manifestations of urologic diseases and quickly confirm your diagnoses.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Inside front cover - p. iii 5. Copyright - p. iii 6. Dedication - p. iii 7. Contributors - p. iii 8. Preface - p. iii 9. Table of contents - p. iii 10. List of Illustrations - p. iii 11. List of Tables - p. iii 12. A: Nonneoplastic Disease of the Prostate - p. iii 13. Chapter 1: Anatomy and histology of the prostate - p. iii 14. Chapter 2: Seminal vesicle/ejaculatory duct - p. 6 15. Chapter 3: Cowper gland - p. 9 16. Chapter 4: Benign prostatic hyperplasia - p. 11 17. Chapter 5: Acute inflammation of the prostate - p. 14 18. Chapter 6: Chronic inflammation of the prostate - p. 16 19. Chapter 7: Nonspecific granulomatous prostatitis - p. 18 20. Chapter 8: Post-biopsy granuloma - p. 20 21. Chapter 9: Prostatic xanthoma - p. 21 22. Chapter 10: Granulomatous prostatitis of infectious etiology - p. 22 23. Chapter 11: Simple atrophy - p. 24 24. Chapter 12: Cystic atrophy - p. 25 25. Chapter 13: Postatrophy hyperplasia - p. 26 26. Chapter 14: Partial atrophy - p. 28 27. Chapter 15: Adenosis - p. 30 28. Chapter 16: Sclerosing adenosis - p. 32 29. Chapter 17: Clear cell cribriform hyperplasia - p. 35 30. Chapter 18: Hyperplasia of mesonephric remnants - p. 37 31. Chapter 19: Basal cell hyperplasia - p. 39 32. Chapter 20: Urothelial metaplasia - p. 42 33. Chapter 21: Squamous metaplasia - p. 43 34. Chapter 22: Mucin cell metaplasia - p. 44 35. Chapter 23: Neuroendocrine cells involving the prostate - p. 45 36. Chapter 24: Verumontanum mucosal gland hyperplasia - p. 47 37. Chapter 25: Prostatic infarct - p. 48 38. B: Neoplastic Disease of the Prostate - p. 50 39. Chapter 26: High-grade prostatic intraepithelial neoplasia (HGPIN) - p. 50 40. Chapter 27: Intraductal carcinoma of the prostate - p. 55 41. Chapter 28: Prostatic carcinoma, usual variant - p. 58 42. Chapter 29: Prostatic carcinoma, atrophic variant - p. 65 43. Chapter 30: Prostatic carcinoma, foamy gland variant - p. 67 44. Chapter 31: Prostatic carcinoma, pseudohyperplastic variant - p. 69 45. Chapter 32: Prostatic carcinoma, mucinous variant - p. 72 46. Chapter 33: Prostatic carcinoma, microcystic variant - p. 74 47. Chapter 34: Prostatic intraepithelial neoplasia (PIN)-like adenocarcinoma - p. 77 48. Chapter 35: Sarcomatoid carcinoma - p. 80 49. Chapter 36: Pleomorphic giant cell carcinoma of the prostate - p. 82 50. Chapter 37: Lymphoepithelioma-like carcinoma of the prostate - p. 84 51. Chapter 38: Prostate carcinoma with squamous differentiation - p. 85 52. Chapter 39: Ductal adenocarcinoma - p. 87 53. Chapter 40: Prostatic adenocarcinoma with neuroendocrine differentiation - p. 90 54. Chapter 41: Well-differentiated neuroendocrine tumor - p. 93 55. Chapter 42: Small cell carcinoma, prostate - p. 96 56. Chapter 43: Prostatic basal cell adenoma - p. 99 57. Chapter 44: Basal cell carcinoma of the prostate - p. 101 58. Chapter 45: Squamous neoplasms including squamous cell and adenosquamous carcinoma - p. 103 59. Chapter 46: Urothelial carcinoma - p. 104 60. Chapter 47: Prostatic stromal tumors of uncertain malignant potential - p. 107 61. Chapter 48: Prostatic stromal sarcoma - p. 110 62. Chapter 49: Atypical glands suspicious for prostatic carcinoma - p. 112 63. Chapter 50: High-grade prostatic intraepithelial neoplasia with adjacent atypical glands - p. 115 64. Chapter 51: Radiation-induced changes - p. 117 65. Chapter 52: Hormonal ablation-induced changes - p. 120 66. Chapter 53: Cryoablation therapy-induced changes - p. 123 67. Chapter 54: Immunohistochemical work-up of prostate carcinoma - p. 126 68. Chapter 55: Gleason grading of prostate carcinoma - p. 129 69. Chapter 56: Prostate cancer staging in radical prostatectomy - p. 133 70. Chapter 57: Genetics and genomics in prostate cancer - p. 137 71. Chapter 58: Work-up of “vanishing” cancer in radical prostatectomy - p. 139 72. Chapter 59: Nonprostatic adenocarcinoma involving the prostate - p. 140 73. C: Seminal Vesicles - p. 142 74. Chapter 60: Anatomy and histology of seminal vesicles - p. 142 75. Chapter 61: Amyloidosis - p. 146 76. Chapter 62: Seminal vesicle adenocarcinoma - p. 148 77. Chapter 63: Mixed epithelial and stromal tumor - p. 149 78. D: Nonneoplastic Disease of the Urinary Bladder - p. 151 79. Chapter 64: Anatomy and histology of the urinary bladder - p. 151 80. Chapter 65: von Brunn nests - p. 155 81. Chapter 66: Cystitis cystica et glandularis - p. 156 82. Chapter 67: Squamous metaplasia - p. 158 83. Chapter 68: Intestinal metaplasia - p. 160 84. Chapter 69: Nephrogenic metaplasia/adenoma - p. 162 85. Chapter 70: Polypoid and papillary cystitis - p. 165 86. Chapter 71: Follicular cystitis - p. 167 87. Chapter 72: Giant cell cystitis - p. 168 88. Chapter 73: Interstitial cystitis/painful bladder syndrome - p. 169 89. Chapter 74: Eosinophilic cystitis - p. 171 90. Chapter 75: Infectious cystitis - p. 173 91. Chapter 76: Malakoplakia - p. 177 92. Chapter 77: Granulomatous cystitis after BCG - p. 179 93. Chapter 78: Radiation cystitis - p. 181 94. Chapter 79: Chemotherapy-induced cystitis - p. 183 95. Chapter 80: Endometriosis of the bladder - p. 185 96. Chapter 81: Bladder endocervicosis - p. 188 97. Chapter 82: Bladder exstrophy - p. 191 98. Chapter 83: Urachal anomaly - p. 192 99. Chapter 84: Bladder diverticulum - p. 194 100. Chapter 85: Ectopic prostate tissue - p. 196 101. E: Neoplastic Disease of the Urinary Bladder - p. 198 102. Chapter 86: Urothelial proliferation of uncertain malignant potential - p. 198 103. Chapter 87: Reactive urothelial atypia - p. 201 104. Chapter 88: Urothelial atypia of unknown significance - p. 203 105. Chapter 89: Urothelial dysplasia - p. 204 106. Chapter 90: Urothelial carcinoma in situ - p. 206 107. Chapter 91: Urothelial papilloma - p. 208 108. Chapter 92: Inverted papilloma - p. 210 109. Chapter 93: Papillary urothelial neoplasm of low malignant potential - p. 213 110. Chapter 94: Low-grade papillary urothelial carcinoma - p. 215 111. Chapter 95: High-grade papillary urothelial carcinoma - p. 217 112. Chapter 96: Invasive urothelial carcinoma - p. 219 113. Chapter 97: Urothelial carcinoma with inverted growth pattern - p. 222 114. Chapter 98: Urothelial carcinoma with squamous differentiation - p. 224 115. Chapter 99: Urothelial carcinoma with villoglandular differentiation - p. 225 116. Chapter 100: Urothelial carcinoma, plasmacytoid variant - p. 227 117. Chapter 101: Urothelial carcinoma, nested variant - p. 230 118. Chapter 102: Urothelial carcinoma, micropapillary variant - p. 233 119. Chapter 103: Urothelial carcinoma, microcystic variant - p. 236 120. Chapter 104: Urothelial carcinoma, lymphoepithelioma-like carcinoma variant - p. 238 121. Chapter 105: Urothelial carcinoma, clear cell (glycogen-rich) variant - p. 240 122. Chapter 106: Lipid-rich urothelial carcinoma - p. 242 123. Chapter 107: Urothelial carcinoma, giant cell variant - p. 243 124. Chapter 108: Urothelial carcinoma with syncytiotrophoblastic giant cells - p. 245 125. Chapter 109: Urothelial carcinoma with rhabdoid differentiation - p. 248 126. Chapter 110: Urothelial carcinoma similar to giant cell tumor of bone - p. 250 127. Chapter 111: Undifferentiated urothelial carcinomas - p. 252 128. Chapter 112: Small cell carcinoma of the urinary bladder - p. 254 129. Chapter 113: Urothelial carcinoma with unusual stromal reactions - p. 256 130. Chapter 114: Urothelial carcinoma with sarcomatoid differentiation - p. 257 131. Chapter 115: Villous adenoma - p. 260 132. Chapter 116: Adenocarcinoma - p. 262 133. Chapter 117: Clear cell adenocarcinoma - p. 264 134. Chapter 118: Urachal adenocarcinoma - p. 266 135. Chapter 119: Squamous cell carcinoma - p. 268 136. Chapter 120: Paraganglioma - p. 270 137. Chapter 121: Staging of urothelial carcinoma of the urinary bladder and urethra - p. 272 138. Chapter 122: Molecular genomics of bladder cancer - p. 274 139. Chapter 123: Secondary spread of prostate carcinoma to the bladder - p. 278 140. Chapter 124: Secondary adenocarcinoma involving the bladder, other than prostatic carcinoma - p. 280 141. F: Nonneoplastic Disease of the Kidney - p. 283 142. Chapter 125: Anatomy of the kidney - p. 283 143. Chapter 126: Renal dysplasia - p. 287 144. Chapter 127: Localized cystic disease of the kidney - p. 289 145. Chapter 128: Autosomal recessive polycystic kidney disease - p. 290 146. Chapter 129: Autosomal dominant polycystic kidney disease - p. 292 147. Chapter 130: Medullary sponge kidney - p. 295 148. Chapter 131: Acquired cystic renal disease - p. 296 149. Chapter 132: Simple cortical cyst - p. 298 150. Chapter 133: Acute pyelonephritis - p. 299 151. Chapter 134: Chronic nonobstructive pyelonephritis - p. 301 152. Chapter 135: Chronic obstructive pyelonephritis - p. 303 153. Chapter 136: Xanthogranulomatous pyelonephritis - p. 305 154. Chapter 137: Renal papillary necrosis - p. 307 155. Chapter 138: Benign nephrosclerosis - p. 308 156. Chapter 139: Malignant nephrosclerosis - p. 311 157. Chapter 140: Acute kidney injury (acute tubular necrosis) - p. 313 158. Chapter 141: Acute interstitial nephritis - p. 315 159. Chapter 142: Infectious interstitial nephritis - p. 317 160. G: Neoplastic Disease of the Kidney - p. 319 161. Chapter 143: Papillary adenoma - p. 319 162. Chapter 144: Renal oncocytoma - p. 322 163. Chapter 145: Clear cell renal cell carcinoma - p. 325 164. Chapter 146: Multilocular cystic renal neoplasm of low malignant potential - p. 328 165. Chapter 147: Papillary renal cell carcinoma - p. 330 166. Chapter 148: Chromophobe renal cell carcinoma - p. 335 167. Chapter 149: Fumarate hydratase-deficient renal cell carcinoma, including hereditary leiomyomatosis and renal cell carcinoma syndrome - p. 337 168. Chapter 150: Collecting duct carcinoma - p. 339 169. Chapter 151: Renal medullary carcinoma - p. 342 170. Chapter 152: Mit family translocation renal cell carcinoma - p. 344 171. Chapter 153: Succinate dehydrogenase-deficient renal cell carcinoma - p. 346 172. Chapter 154: Mucinous tubular and spindle cell carcinoma - p. 348 173. Chapter 155: Tubulocystic carcinoma - p. 350 174. Chapter 156: Acquired cystic kidney disease-associated renal cell carcinoma - p. 353 175. Chapter 157: Thyroid-like follicular renal cell carcinoma - p. 355 176. Chapter 158: Clear cell papillary renal cell carcinoma - p. 357 177. Chapter 159: Renal cell carcinoma with fibromyomatous stroma - p. 360 178. Chapter 160: Eosinophilic solid cystic renal cell carcinoma - p. 362 179. Chapter 161: Renal cell carcinoma with somatic mutations in TSC/mTORC1 genes - p. 364 180. Chapter 162: Renal cell carcinoma with sarcomatoid differentiation - p. 367 181. Chapter 163: Renal cell carcinoma, unclassified type - p. 370 182. Chapter 164: Grading system for renal cell carcinoma - p. 372 183. Chapter 165: Staging of renal cell carcinoma - p. 375 184. Chapter 166: Renal cell carcinoma in von Hippel-Lindau disease - p. 377 185. Chapter 167: Renal cell neoplasms in Birt-Hogg-Dubé (BHD) syndrome - p. 379 186. Chapter 168: Renal tumors in tuberous sclerosis complex (TSC) - p. 381 187. Chapter 169: Metanephric adenoma - p. 384 188. Chapter 170: Metanephric stromal tumor - p. 386 189. Chapter 171: Wilms tumor - p. 388 190. Chapter 172: Nephrogenic rests and nephroblastomatosis - p. 391 191. Chapter 173: Congenital mesoblastic nephroma (CMN) - p. 392 192. Chapter 174: Rhabdoid tumor of the kidney - p. 395 193. Chapter 175: Clear cell sarcoma of the kidney - p. 397 194. Chapter 176: Ossifying renal tumor of infancy - p. 399 195. Chapter 177: Renal angiomyolipoma - p. 401 196. Chapter 178: Epithelioid angiomyolipoma - p. 405 197. Chapter 179: Juxtaglomerular cell tumor - p. 408 198. Chapter 180: Renal medullary fibroma (renomedullary interstitial cell tumor) - p. 409 199. Chapter 181: Mixed epithelial and stromal tumor family - p. 411 200. Chapter 182: Primary renal synovial sarcoma - p. 413 201. Chapter 183: Renal carcinoid tumor - p. 415 202. H: Renal Pelvis and Ureter - p. 417 203. Chapter 184: Ureteropelvic junction obstruction - p. 417 204. Chapter 185: Idiopathic retroperitoneal fibrosis, including IgG4-related disease - p. 421 205. Chapter 186: Fibroepithelial polyp of the ureter and renal pelvis - p. 423 206. Chapter 187: Ureteral urothelial carcinoma and staging - p. 424 207. Chapter 188: Staging for pelvic urothelial carcinoma - p. 425 208. I: Nonneoplastic Disease of the Testis - p. 426 209. Chapter 189: Testis: Anatomy and histology - p. 426 210. Chapter 190: Cryptorchidism - p. 429 211. Chapter 191: Testiculosplenic fusion - p. 432 212. Chapter 192: Adrenal cortical rests - p. 434 213. Chapter 193: Spermatic cord torsion and testicular infarction - p. 436 214. Chapter 194: Testicular microlithiasis - p. 438 215. Chapter 195: Vasculitis - p. 440 216. Chapter 196: Male infertility workup - p. 442 217. Chapter 197: Maturation arrest - p. 444 218. Chapter 198: Hypospermatogenesis - p. 445 219. Chapter 199: Germ cell aplasia, sertoli cell-only syndrome - p. 447 220. Chapter 200: Excurrent duct obstruction - p. 449 221. Chapter 201: Pre-pubertal gonadotropin deficiency - p. 450 222. Chapter 202: Postpubertal gonadotrophin deficiency - p. 452 223. Chapter 203: Viral orchitis - p. 453 224. Chapter 204: Granulomatous orchiepididymitis - p. 454 225. Chapter 205: Nonspecific granulomatous orchitis - p. 456 226. Chapter 206: Androgen insensitivity syndrome - p. 458 227. Chapter 207: Klinefelter syndrome - p. 459 228. Chapter 208: Testicular tumor of the adrenogenital syndrome - p. 461 229. Chapter 209: Embryonic testicular regression (Vanishing testis syndrome) - p. 464 230. Chapter 210: Gonadal dysgenesis - p. 466 231. J: Neoplastic Disease of the Testis - p. 468 232. Chapter 211: Germ cell neoplasia in situ - p. 468 233. Chapter 212: Specific forms of intratubular germ cell neoplasia - p. 471 234. Chapter 213: Seminoma - p. 472 235. Chapter 214: Embryonal carcinoma - p. 476 236. Chapter 215: Postpubertal-type yolk sac tumor - p. 479 237. Chapter 216: Postpubertal-type teratoma - p. 482 238. Chapter 217: Mixed germ cell tumor - p. 484 239. Chapter 218: Teratoma with somatic-type malignancies - p. 486 240. Chapter 219: Choriocarcinoma - p. 488 241. Chapter 220: Non-choriocarcinomatous trophoblastic tumors - p. 490 242. Chapter 221: Regressed germ cell tumors - p. 491 243. Chapter 222: Spermatocytic tumor - p. 493 244. Chapter 223: Prepubertal-type teratoma, testicular carcinoid tumor - p. 495 245. Chapter 224: Teratoma, prepubertal-type, dermoid cyst - p. 497 246. Chapter 225: Prepubertal teratoma, epidermoid cyst - p. 499 247. Chapter 226: Yolk sac tumor, prepubertal type - p. 500 248. Chapter 227: Leydig cell tumor - p. 501 249. Chapter 228: Sertoli cell tumor - p. 504 250. Chapter 229: Sclerosing sertoli cell tumor - p. 507 251. Chapter 230: Large cell calcifying sertoli cell tumor - p. 509 252. Chapter 231: Adult granulosa cell tumor - p. 511 253. Chapter 232: Juvenile granulosa cell tumor - p. 513 254. Chapter 233: Fibrothecoma - p. 515 255. Chapter 234: Stromal tumor of the testis, mixed and unclassified type - p. 517 256. Chapter 235: Myoid gonadal stromal tumor - p. 519 257. Chapter 236: Gonadoblastoma - p. 521 258. Chapter 237: Testicular lymphoma - p. 523 259. Chapter 238: Ovarian epithelial-type testicular tumors - p. 525 260. Chapter 239: Tumors of the rete testis - p. 529 261. Chapter 240: Testicular cancer staging - p. 532 262. K: Spermatic Cord and Testicular Adnexa - p. 534 263. Chapter 241: Appendix testis - p. 534 264. Chapter 242: Appendix epididymis - p. 537 265. Chapter 243: Glandular inclusions in inguinal herniorrhaphy specimens - p. 538 266. Chapter 244: Hydrocele - p. 540 267. Chapter 245: Spermatocele - p. 542 268. Chapter 246: Vasitis nodosa - p. 544 269. Chapter 247: Sperm granuloma - p. 546 270. Chapter 248: Adenomatoid tumor - p. 548 271. Chapter 249: Fibrous pseudotumor - p. 550 272. Chapter 250: Paratesticular idiopathic smooth muscle hyperplasia - p. 552 273. Chapter 251: Papillary cystadenoma of the epididymis - p. 553 274. Chapter 252: Paratesticular lipoma - p. 554 275. Chapter 253: Paratesticular liposarcoma - p. 555 276. Chapter 254: Paratesticular rhabdomyosarcoma - p. 557 277. Chapter 255: Leiomyoma of the spermatic cord and testicular adnexa - p. 559 278. Chapter 256: Paratesticular leiomyosarcoma - p. 561 279. Chapter 257: Aggressive angiomyxoma of the male genital region - p. 562 280. Chapter 258: Cellular angiofibroma - p. 564 281. Chapter 259: Malignant mesothelioma, paratesticular - p. 566 282. Chapter 260: Epithelial tumors of the rete testis - p. 568 283. L: Disease of the Penis, Urethra, and Scrotum - p. 570 284. Chapter 261: Fibroepithelial polyp of the urethra - p. 570 285. Chapter 262: Urethral caruncle - p. 573 286. Chapter 263: Urethral diverticulum - p. 575 287. Chapter 264: Urethral stricture - p. 577 288. Chapter 265: Polypoid urethritis - p. 578 289. Chapter 266: Condyloma acuminatum - p. 579 290. Chapter 267: Prostatic-type urethral polyp - p. 581 291. Chapter 268: Urethral urothelial carcinoma associated with bladder urothelial carcinoma - p. 583 292. Chapter 269: Primary urethral carcinoma - p. 585 293. Chapter 270: Urethral adenocarcinoma - p. 587 294. Chapter 271: Clear cell adenocarcinoma of the urethra - p. 589 295. Chapter 272: Zoon balanitis - p. 591 296. Chapter 273: Lichen sclerosus et atrophicus (balanitis xerotica obliterans) - p. 592 297. Chapter 274: Pseudoepitheliomatous keratotic micaceous balanitis - p. 594 298. Chapter 275: Peyronie disease - p. 596 299. Chapter 276: Squamous hyperplasia of the penis - p. 597 300. Chapter 277: Penile intraepithelial neoplasia (PeIN) - p. 598 301. Chapter 278: Differentiated penile intraepithelial neoplasia - p. 600 302. Chapter 279: Squamous cell carcinoma of the penis, usual type - p. 602 303. Chapter 280: Basaloid squamous cell carcinoma - p. 604 304. Chapter 281: Squamous cell carcinoma, papillary-basaloid - p. 606 305. Chapter 282: Penile warty (condylomatous) carcinoma - p. 608 306. Chapter 283: Squamous cell carcinoma, warty-basaloid - p. 610 307. Chapter 284: Clear cell squamous cell carcinoma - p. 612 308. Chapter 285: Lymphoepithelioma-like carcinoma - p. 614 309. Chapter 286: Squamous cell carcinoma, verrucous - p. 615 310. Chapter 287: Squamous cell carcinoma, papillary - p. 617 311. Chapter 288: Squamous cell carcinoma, pseudohyperplastic variant - p. 619 312. Chapter 289: Squamous cell carcinoma, pseudoglandular - p. 621 313. Chapter 290: Squamous cell carcinoma, cuniculatum - p. 623 314. Chapter 291: Sarcomatoid (spindle cell) squamous cell carcinoma of the penis - p. 625 315. Chapter 292: Adenosquamous carcinoma of the penis - p. 627 316. Chapter 293: Mixed squamous cell carcinoma of the penis - p. 628 317. Chapter 294: Penile basal cell carcinoma - p. 630 318. Chapter 295: Extramammary Paget disease of the penis and scrotum - p. 631 319. Chapter 296: Merkel cell carcinoma of the genitourinary tract - p. 634 320. Chapter 297: Sclerosing lipogranuloma - p. 636 321. Chapter 298: Idiopathic scrotal calcinosis - p. 638 322. Chapter 299: Genital melanosis and lentiginosis - p. 640 323. Chapter 300: Mucosal melanoma of the genitourinary system - p. 641 324. Chapter 301: Staging for penile squamous cell carcinoma - p. 643 325. Chapter 302: Staging for urethral carcinoma - p. 644 326. M: Soft Tissue Tumors - p. 646 327. Chapter 303: Inflammatory myofibroblastic tumor of the bladder - p. 646 328. Chapter 304: Leiomyoma of the bladder - p. 649 329. Chapter 305: Leiomyosarcoma of the bladder - p. 650 330. Chapter 306: Solitary fibrous tumor - p. 652 331. Chapter 307: Gastrointestinal stromal tumor of the genitourinary tract - p. 654 332. Chapter 308: Lymphomas of the genitourinary organs - p. 656 333. Index - p. 659 334. Inside back cover - p. 659