Vaccinology and Methods in Vaccine Research is a combination of cutting-edge methodologies, experimental approaches and literature reviews. The book covers all aspects of vaccine development, including basic immunology (focusing on the stimulation of adaptive immunity, which is required for vaccine efficacy), approaches to vaccine design and target validation, vaccine biomanufacturer and clinical development. Existing vaccinology resources are theoretical reference books, whereas this book provides a practical handbook for use in the research lab and classroom by those working in vaccinology and training others in the field.
It is authored and edited by scientists actively engaged in vaccine research and development for day-to-day teaching/methodological advice.
1. Vaccinology and Methods in Vaccine Research - p. iv 2. Cover - p. iv 3. Title page - p. iv 4. Copyright - p. iv 5. Contents - p. iv 6. List of contributors - p. xi 7. Preface - p. xiii 8. Acknowledgements - p. xv 9. Chapter 1 Immunology and the concept of vaccination - p. 1 10. Chapter 2 Vaccine types and reverse vaccinology - p. 31 11. Chapter 3 Dendritic cells as vaccine targets - p. 57 12. Chapter 4 Vaccine development: from the laboratory to the field - p. 95 13. Chapter 5 Harnessing the power of CD8+ T-cells: identification and validation of peptides bound to major histocompatibility complex class I by immunopeptidomics - p. 133 14. Chapter 6 Virus-like particle vaccines - p. 163 15. Chapter 7 Approaches to cancer vaccination - p. 177 16. Chapter 8 Vaccines against SARS-CoV-2 - p. 201 17. Chapter 9 Adjuvants, immunomodulators, and adaptogens - p. 223 18. Chapter 10 GMP manufacture and quality control - p. 281 19. Chapter 11 Testing vaccines: essential steps in clinical trial design - p. 295 20. Index - p. 311
Vaccinology and Methods in Vaccine Research is a combination of cutting-edge methodologies, experimental approaches and literature reviews. The book covers all aspects of vaccine development, including basic immunology (focusing on the stimulation of adaptive immunity, which is required for vaccine efficacy), approaches to vaccine design and target validation, vaccine biomanufacturer and clinical development. Existing vaccinology resources are theoretical reference books, whereas this book provides a practical handbook for use in the research lab and classroom by those working in vaccinology and training others in the field.
It is authored and edited by scientists actively engaged in vaccine research and development for day-to-day teaching/methodological advice.
1. Vaccinology and Methods in Vaccine Research - p. iv 2. Cover - p. iv 3. Title page - p. iv 4. Copyright - p. iv 5. Contents - p. iv 6. List of contributors - p. xi 7. Preface - p. xiii 8. Acknowledgements - p. xv 9. Chapter 1 Immunology and the concept of vaccination - p. 1 10. Chapter 2 Vaccine types and reverse vaccinology - p. 31 11. Chapter 3 Dendritic cells as vaccine targets - p. 57 12. Chapter 4 Vaccine development: from the laboratory to the field - p. 95 13. Chapter 5 Harnessing the power of CD8+ T-cells: identification and validation of peptides bound to major histocompatibility complex class I by immunopeptidomics - p. 133 14. Chapter 6 Virus-like particle vaccines - p. 163 15. Chapter 7 Approaches to cancer vaccination - p. 177 16. Chapter 8 Vaccines against SARS-CoV-2 - p. 201 17. Chapter 9 Adjuvants, immunomodulators, and adaptogens - p. 223 18. Chapter 10 GMP manufacture and quality control - p. 281 19. Chapter 11 Testing vaccines: essential steps in clinical trial design - p. 295 20. Index - p. 311
