Whole Cell Biocatalysis, a volume in the Foundations and Frontiers of Enzymology series, offers a detailed overview of the process of biocatalysis using whole cells as an alternative to enzyme biocatalysis. The book examines the potential applications and advantages of whole cell biocatalysis, including its use in the production of fine chemicals, renewable energy, and drug discovery and development. Whole cell biocatalysis for large scale production and non-conventional media are also covered. In addition, the latest methods and techniques are investigated, including cell immobilization, permeabilization, synthetic biology, computational metabolic engineering, and molecular genetics.
This book provides a comprehensive summary on whole cell biocatalysis and the latest developments in this emerging field. It is an invaluable reference for researchers working across biochemistry, enzymology, biotechnology, and related fields.
1. Whole-Cell Biocatalysis: Fundamentals and Applications - p. i 2. Cover image - p. i 3. Title page - p. i 4. Table of Contents - p. i 5. Front Matter - p. i 6. Copyright - p. iv 7. Contributors - p. xiii 8. About the editors - p. xvii 9. Preface - p. xix 10. Chapter 1 Advantages and new potential applications of whole-cell biocatalysis - p. 1 11. Chapter 2 Reprogramming microbial cells to improve the production of biopharmaceuticals and fine chemicals - p. 21 12. Chapter 3 Mitigation of greenhouse gas emissions from biogas-producing facilities: A novel whole-cell technology platform based on anaerobic oxidation of methane - p. 74 13. Chapter 4 Computational metabolic engineering using genome-scale metabolic models and constraint-based methods - p. 101 14. Chapter 5 Whole-cell biocatalysis in nonconventional media - p. 123 15. Chapter 6 Nanostructured magnetic systems in whole-cell biocatalysis - p. 143 16. Chapter 7 Filamentous fungi as biopharmaceutical protein factories - p. 171 17. Chapter 8 Proteomic analysis: Application to the study of signal transduction pathways in Penicillium chrysogenum and Acremonium chrysogenum - p. 193 18. Chapter 9 Fungal lipase obtained by surface adhesion fermentation using magnetic chitosan-coated nanoparticles - p. 209 19. Chapter 10 In vitro plant cultures as a viable biotechnological tool for the biosynthesis of steroidal hormones of clinical interest - p. 221 20. Chapter 11 Whole-cell biocatalysis for large-scale production - p. 271 21. Author Index - p. 301 22. Subject Index - p. 329
Whole Cell Biocatalysis, a volume in the Foundations and Frontiers of Enzymology series, offers a detailed overview of the process of biocatalysis using whole cells as an alternative to enzyme biocatalysis. The book examines the potential applications and advantages of whole cell biocatalysis, including its use in the production of fine chemicals, renewable energy, and drug discovery and development. Whole cell biocatalysis for large scale production and non-conventional media are also covered. In addition, the latest methods and techniques are investigated, including cell immobilization, permeabilization, synthetic biology, computational metabolic engineering, and molecular genetics.
This book provides a comprehensive summary on whole cell biocatalysis and the latest developments in this emerging field. It is an invaluable reference for researchers working across biochemistry, enzymology, biotechnology, and related fields.
1. Whole-Cell Biocatalysis: Fundamentals and Applications - p. i 2. Cover image - p. i 3. Title page - p. i 4. Table of Contents - p. i 5. Front Matter - p. i 6. Copyright - p. iv 7. Contributors - p. xiii 8. About the editors - p. xvii 9. Preface - p. xix 10. Chapter 1 Advantages and new potential applications of whole-cell biocatalysis - p. 1 11. Chapter 2 Reprogramming microbial cells to improve the production of biopharmaceuticals and fine chemicals - p. 21 12. Chapter 3 Mitigation of greenhouse gas emissions from biogas-producing facilities: A novel whole-cell technology platform based on anaerobic oxidation of methane - p. 74 13. Chapter 4 Computational metabolic engineering using genome-scale metabolic models and constraint-based methods - p. 101 14. Chapter 5 Whole-cell biocatalysis in nonconventional media - p. 123 15. Chapter 6 Nanostructured magnetic systems in whole-cell biocatalysis - p. 143 16. Chapter 7 Filamentous fungi as biopharmaceutical protein factories - p. 171 17. Chapter 8 Proteomic analysis: Application to the study of signal transduction pathways in Penicillium chrysogenum and Acremonium chrysogenum - p. 193 18. Chapter 9 Fungal lipase obtained by surface adhesion fermentation using magnetic chitosan-coated nanoparticles - p. 209 19. Chapter 10 In vitro plant cultures as a viable biotechnological tool for the biosynthesis of steroidal hormones of clinical interest - p. 221 20. Chapter 11 Whole-cell biocatalysis for large-scale production - p. 271 21. Author Index - p. 301 22. Subject Index - p. 329
