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Wound Healing, and the Myofibroblast: A Historical and Biological Perspective is the fruit of an interdisciplinary and international collaboration involving a historian of medicine (Dr. Zampieri), a physician (Dr. Coen), and a researcher (Prof. Gabbiani, world-renowned for his discovery of the myofibroblast). This book aims to draw a concise yet complete description of the conceptual evolution of wound healing, fibrosis and fibrosis-related pathologies from antiquity to present time, as well as commenting on the role of the myofibroblast and the key cell type essential for tissue repair and fibrosis (from its identification in 1971 throughout its 50-years-old history).

By viewing this complex and century-long history from different perspectives, the book's authors aim to draw an exhaustive overview, with the hope of inspiring new and fruitful basic and clinical research.

  • Interdisciplinary collaboration: complementary views from medical historian, a physician and a researcher
  • A concise but detailed history of fibrosis, readers can discover the major scientific breakthroughs along this history
  • Includes the pathophysiology of various fibrotic diseases
  • Explores the role of myofibroblast in fibrosis development

1. Wound Healing, Fibrosis, and the Myofibroblast - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Cover image legend - p. Page v 7. Dedication - p. Page vi 8. Preface I : The value of interdisciplinary collaboration in medicine and biology - p. Page vi 9. Preface II : Myofibroblasts: 50 years and aging well - p. Page x 10. Preface III - p. Page xiv 11. Acknowledgments - p. Page xv 12. List of Illustrations - p. Page xvi 13. Chapter 1 : Fibrous tissue, fibrosis, and the fibroblast - p. Page xvi 14. Chapter 2 : Wound healing and wound contraction - p. Page 12 15. Chapter 3 : Fibrotic diseases - p. Page 25 16. Chapter 4 : The myofibroblast: Role in fibrosis development - p. Page 77 17. Chapter 5 : Conclusions and perspectives - p. Page 96 18. Index - p. Page 100

Descripcion
Descripción

Wound Healing, and the Myofibroblast: A Historical and Biological Perspective is the fruit of an interdisciplinary and international collaboration involving a historian of medicine (Dr. Zampieri), a physician (Dr. Coen), and a researcher (Prof. Gabbiani, world-renowned for his discovery of the myofibroblast). This book aims to draw a concise yet complete description of the conceptual evolution of wound healing, fibrosis and fibrosis-related pathologies from antiquity to present time, as well as commenting on the role of the myofibroblast and the key cell type essential for tissue repair and fibrosis (from its identification in 1971 throughout its 50-years-old history).

By viewing this complex and century-long history from different perspectives, the book's authors aim to draw an exhaustive overview, with the hope of inspiring new and fruitful basic and clinical research.

  • Interdisciplinary collaboration: complementary views from medical historian, a physician and a researcher
  • A concise but detailed history of fibrosis, readers can discover the major scientific breakthroughs along this history
  • Includes the pathophysiology of various fibrotic diseases
  • Explores the role of myofibroblast in fibrosis development

1. Wound Healing, Fibrosis, and the Myofibroblast - p. Page i 2. Cover - p. Page i 3. Front Matter - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iv 6. Cover image legend - p. Page v 7. Dedication - p. Page vi 8. Preface I : The value of interdisciplinary collaboration in medicine and biology - p. Page vi 9. Preface II : Myofibroblasts: 50 years and aging well - p. Page x 10. Preface III - p. Page xiv 11. Acknowledgments - p. Page xv 12. List of Illustrations - p. Page xvi 13. Chapter 1 : Fibrous tissue, fibrosis, and the fibroblast - p. Page xvi 14. Chapter 2 : Wound healing and wound contraction - p. Page 12 15. Chapter 3 : Fibrotic diseases - p. Page 25 16. Chapter 4 : The myofibroblast: Role in fibrosis development - p. Page 77 17. Chapter 5 : Conclusions and perspectives - p. Page 96 18. Index - p. Page 100

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