The Year Book of Neonatal and Perinatal Medicine brings you abstracts of the articles that reported the year's breakthrough developments in neonatal and perinatal medicine, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! Chapters in this annual cover the most current information on all aspects of neonatal and perinatal medicine from genetics to labor and delivery to issues related to many key bodily systems (heart, respiratory, nervous system, etc.) of newborns. Other topics for 2004 include neurology, gastroenterology and nutrition, medical disorders of pregnancy, fetal evaluation, and neonatal behavior.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Fetal Laboratory Medicine: On the Frontier of Maternal–Fetal Medicine - p. 8 5. Reproductive Technologies and the Risk of Birth Defects - p. 9 6. Placental pathology in asphyxiated newborns meeting the criteria for therapeutic hypothermia - p. 10 7. Accuracy of imaging parameters in the prediction of lethal pulmonary hypoplasia secondary to mid-trimester prelabor rupture of fetal membranes: a systematic review and meta-analysis - p. 11 8. Outcome of fetal exomphalos diagnosed at 11–14 weeks of gestation - p. 12 9. Antenatal Corticosteroids Promote Survival of Extremely Preterm Infants Born at 22 to 23 Weeks of Gestation - p. 13 10. Association of Antenatal Corticosteroids With Mortality and Neurodevelopmental Outcomes Among Infants Born at 22 to 25 Weeks’ Gestation - p. 14 11. Association of Antenatal Corticosteroids With Mortality and Neurodevelopmental Outcomes Among Infants Born at 22 to 25 Weeks' Gestation - p. 15 12. Magnesium sulfate therapy for the prevention of cerebral palsy in preterm infants: a decision-analytic and economic analysis - p. 16 13. Improving Quality of Care for Maternal and Newborn Health: Prospective Pilot Study of the WHO Safe Childbirth Checklist Program - p. 17 14. Use of alcohol-free antimicrobial mouth rinse is associated with decreased incidence of preterm birth in a high-risk population - p. 18 15. The Prediction and Cost of Futility in the NICU - p. 19 16. Survival rates in extremely low birthweight infants depend on the denominator: avoiding potential for bias by specifying denominators - p. 20 17. Improving Survival of Extremely Preterm Infants Born Between 22 and 25 Weeks of Gestation - p. 21 18. Effect of Antenatal Corticosteroids on Fetal Growth and Gestational Age at Birth - p. 22 19. Causes of Death Among Stillbirths - p. 23 20. Assessing the Optimal Definition of Oligohydramnios Associated With Adverse Neonatal Outcomes - p. 24 21. Antenatal Steroids for Treatment of Fetal Lung Immaturity After 34 Weeks of Gestation: An Evaluation of Neonatal Outcomes - p. 25 22. Antenatal Steroids for Treatment of Fetal Lung Immaturity After 34 Weeks of Gestation: An Evaluation of Neonatal Outcomes - p. 26 23. Outcome of Extremely Low Birth Weight Infants Who Received Delivery Room Cardiopulmonary Resuscitation - p. 27 24. Gestational Age at Birth and Mortality in Young Adulthood - p. 28 25. Prenatal environmental risk factors for genital malformations in a population of 1442 French male newborns: a nested case–control study - p. 29 26. Brain anomalies in children exposed prenatally to a common organophosphate pesticide - p. 30 27. Complete Screening of 50 Patients with CHARGE Syndrome for Anomalies in the CHD7 Gene Using a Denaturing High-Performance Liquid Chromatography–Based Protocol: New Guidelines and a Proposal for Routine Diagnosis - p. 31 28. Ichthyosis prematurity syndrome: Clinical evaluation of 17 families with a rare disorder of lipid metabolism - p. 32 29. Effectiveness of pulse oximetry versus fetal electrocardiography for the intrapartum evaluation of nonreassuring fetal heart rate - p. 33 30. Diversity of microbes in amniotic fluid - p. 34 31. Neonatal Outcomes After Implementation of Guidelines Limiting Elective Delivery Before 39 Weeks of Gestation - p. 35 32. Maternal and perinatal complications by day of gestation after spontaneous labor at 40–42 weeks of gestation - p. 36 33. Effect of delayed versus early umbilical cord clamping on neonatal outcomes and iron status at 4 months: a randomised controlled trial - p. 37 34. Uterine Rupture With Attempted Vaginal Birth After Cesarean Delivery: Decision-to-Delivery Time and Neonatal Outcome - p. 38 35. Intrapartum Temperature Elevation, Epidural Use, and Adverse Outcome in Term Infants - p. 39 36. Trends and Characteristics of Home Vaginal Birth After Cesarean Delivery in the United States and Selected States - p. 40 37. Changes in labor patterns over 50 years - p. 41 38. Estimating the Probability of Neonatal Early-Onset Infection on the Basis of Maternal Risk Factors - p. 42 39. The Burden of Invasive Early-onset Neonatal Sepsis in the United States, 2005–2008 - p. 43 40. Cytokine screening identifies NICU patients with Gram-negative bacteremia - p. 44 41. Mortality Reduction by Heart Rate Characteristic Monitoring in Very Low Birth Weight Neonates: A Randomized Trial - p. 45 42. Fluconazole Prophylaxis in Extremely Low Birth Weight Infants and Neurodevelopmental Outcomes and Quality of Life at 8 to 10 Years of Age - p. 46 43. Ohio Statewide Quality-Improvement Collaborative to Reduce Late-Onset Sepsis in Preterm Infants - p. 47 44. Prolonged Initial Empirical Antibiotic Treatment is Associated with Adverse Outcomes in Premature Infants - p. 48 45. Relationship Between Maternal and Neonatal Staphylococcus aureus Colonization - p. 49 46. Topical application of chlorhexidine to neonatal umbilical cords for prevention of omphalitis and neonatal mortality in a rural district of Pakistan: a community-based, cluster-randomised trial - p. 50 47. Treatment of Neonatal Sepsis with Intravenous Immune Globulin - p. 51 48. Treatment of Neonatal Sepsis with Intravenous Immune Globulin - p. 52 49. Treatment of Neonatal Sepsis with Intravenous Immune Globulin - p. 53 50. Oral Acyclovir Suppression and Neurodevelopment after Neonatal Herpes - p. 54 51. Oral Acyclovir Suppression and Neurodevelopment after Neonatal Herpes - p. 55 52. Long-term outcome in preterm children with human cytomegalovirus infection transmitted via breast milk - p. 56 53. Association of Prenatal and Postnatal Exposure to Lopinavir-Ritonavir and Adrenal Dysfunction Among Uninfected Infants of HIV-Infected Mothers - p. 57 54. Antibiotic Exposure in the Newborn Intensive Care Unit and the Risk of Necrotizing Enterocolitis - p. 58 55. Saliva Polymerase-Chain-Reaction Assay for Cytomegalovirus Screening in Newborns - p. 59 56. Unrecognized Ingestion of Toxoplasma gondii Oocysts Leads to Congenital Toxoplasmosis and Causes Epidemics in North America - p. 60 57. The long quest for neonatal screening for severe combined immunodeficiency - p. 61 58. Effect of a partially hydrolyzed whey infant formula at weaning on risk of allergic disease in high-risk children: A randomized controlled trial - p. 62 59. Birth Prevalence of Congenital Heart Disease Worldwide: A Systematic Review and Meta-Analysis - p. 63 60. Strategies for Implementing Screening for Critical Congenital Heart Disease - p. 64 61. Targeted Neonatal Echocardiography in the Neonatal Intensive Care Unit: Practice Guidelines and Recommendations for Training: Writing group of the American Society of Echocardiography (ASE) in collaboration with the European Association of Echocardiography (EAE) and the Association for European Pediatric Cardiologists (AEPC) - p. 65 62. Cardiac biomarkers in neonatal hypoxic ischaemia - p. 68 63. B-Type Natriuretic Peptide and Rebound during Treatment for Persistent Pulmonary Hypertension - p. 69 64. Effect of persistent patent ductus arteriosus on mortality and morbidity in very low-birthweight infants - p. 70 65. Selective serotonin reuptake inhibitors during pregnancy and risk of persistent pulmonary hypertension in the newborn: population based cohort study from the five Nordic countries - p. 71 66. Isolated Atrioventricular Block in the Fetus: A Retrospective, Multinational, Multicenter Study of 175 Patients - p. 72 67. Early postnatal hypotension and developmental delay at 24 months of age among extremely low gestational age newborns - p. 73 68. The right ventricular systolic to diastolic duration ratio: a simple prognostic marker in congenital diaphragmatic hernia? - p. 74 69. Which inotrope and when in neonatal and paediatric intensive care? - p. 75 70. Very low-birth-weight infants with congenital cardiac lesions: Is there merit in delaying intervention to permit growth and maturation? - p. 77 71. Complications After the Norwood Operation: An Analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database - p. 78 72. Randomized Controlled Trial of Restrictive Fluid Management in Transient Tachypnea of the Newborn - p. 79 73. Surfactant Deficiency in Transient Tachypnea of the Newborn - p. 80 74. Randomized Trial Comparing 3 Approaches to the Initial Respiratory Management of Preterm Neonates - p. 81 75. Randomized Trial Comparing 3 Approaches to the Initial Respiratory Management of Preterm Neonates - p. 82 76. Avoidance of mechanical ventilation by surfactant treatment of spontaneously breathing preterm infants (AMV): an open-label, randomised, controlled trial - p. 83 77. Mortality in preterm infants with respiratory distress syndrome treated with poractant alfa, calfactant or beractant: a retrospective study - p. 84 78. Preliminary evaluation of a new technique of minimally invasive surfactant therapy - p. 85 79. Mortality in preterm infants with respiratory distress syndrome treated with poractant alfa, calfactant or beractant: a retrospective study - p. 86 80. Nasal Continuous Positive Airway Pressure With Heliox in Preterm Infants With Respiratory Distress Syndrome - p. 87 81. Positive effects of early continuous positive airway pressure on pulmonary function in extremely premature infants: results of a subgroup analysis of the COIN trial - p. 88 82. Predictors of early nasal CPAP failure and effects of various intubation criteria on the rate of mechanical ventilation in preterm infants of <29 weeks gestational age - p. 89 83. Early prediction of nasal continuous positive airway pressure failure in preterm infants less than 30 weeks gestation - p. 90 84. Prediction of Bronchopulmonary Dysplasia by Postnatal Age in Extremely Premature Infants - p. 91 85. Clarithromycin in Preventing Bronchopulmonary Dysplasia in Ureaplasma urealyticum–Positive Preterm Infants - p. 92 86. Clarithromycin in Preventing Bronchopulmonary Dysplasia in Ureaplasma urealyticum–Positive Preterm Infants - p. 93 87. Molecular Identification of Bacteria in Tracheal Aspirate Fluid from Mechanically Ventilated Preterm Infants - p. 94 88. A new method for continuous monitoring of chest wall movement to characterize hypoxemic episodes during HFOV - p. 95 89. Airway obstruction and gas leak during mask ventilation of preterm infants in the delivery room - p. 96 90. Mask leak in one-person mask ventilation compared to two-person in newborn infant manikin study - p. 97 91. Hospital Variation in Nitric Oxide Use for Premature Infants - p. 98 92. Inhaled Nitric Oxide in Preterm Infants: An Individual-Patient Data Meta-analysis of Randomized Trials - p. 99 93. Protocolized management of infants with congenital diaphragmatic hernia: effect on survival - p. 100 94. Application of Criteria Developed by the Task Force on Neonatal Encephalopathy and Cerebral Palsy to Acutely Asphyxiated Neonates - p. 101 95. Childhood Outcomes after Hypothermia for Neonatal Encephalopathy - p. 102 96. Childhood Outcomes after Hypothermia for Neonatal Encephalopathy - p. 103 97. Long-term neuroprotective effects of allopurinol after moderate perinatal asphyxia: follow-up of two randomised controlled trials - p. 104 98. Long-term neuroprotective effects of allopurinol after moderate perinatal asphyxia: follow-up of two randomised controlled trials - p. 105 99. Seven- to eight-year follow-up of the CoolCap trial of head cooling for neonatal encephalopathy - p. 106 100. Xenon Augmented Hypothermia Reduces Early Lactate/N-Acetylaspartate and Cell Death in Perinatal Asphyxia - p. 107 101. The effect of whole-body cooling on brain metabolism following perinatal hypoxic–ischemic injury - p. 108 102. Distribution and severity of hypoxic–ischaemic lesions on brain MRI following therapeutic cooling: selective head versus whole body cooling - p. 109 103. Changes of Positron Emission Tomography in Newborn Infants at Different Gestational Ages, and Neonatal Hypoxic-Ischemic Encephalopathy - p. 110 104. Cytokines and Neurodevelopmental Outcomes in Extremely Low Birth Weight Infants - p. 111 105. Dendrimer-Based Postnatal Therapy for Neuroinflammation and Cerebral Palsy in a Rabbit Model - p. 112 106. DTI reveals network injury in perinatal stroke - p. 113 107. Symptomatic Neonatal Arterial Ischemic Stroke: The International Pediatric Stroke Study - p. 114 108. Effects of Prone and Supine Position on Cerebral Blood Flow in Preterm Infants - p. 115 109. Recording conventional and amplitude-integrated EEG in neonatal intensive care unit - p. 116 110. Impact of Amplitude-Integrated Electroencephalograms on Clinical Care for Neonates With Seizures - p. 117 111. Neonatal Seizures: Treatment Practices Among Term and Preterm Infants - p. 118 112. Grade and laterality of intraventricular haemorrhage to predict 18–22 month neurodevelopmental outcomes in extremely low birthweight infants - p. 119 113. Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity - p. 120 114. Neurologic Outcomes in Very Preterm Infants Undergoing Surgery - p. 121 115. Neonatal Intensive Care Unit Stress Is Associated with Brain Development in Preterm Infants - p. 122 116. Infant regulation of intake: the effect of free glutamate content in infant formulas - p. 123 117. Effects of fetal antiepileptic drug exposure: Outcomes at age 4.5 years - p. 124 118. Normal gut microbiota modulates brain development and behavior - p. 125 119. Current Role of Cryotherapy in Retinopathy of Prematurity: A Report by the American Academy of Ophthalmology - p. 126 120. Association of Antenatal Corticosteroids With Mortality and Neurodevelopmental Outcomes Among Infants Born at 22 to 25 Weeks’ Gestation - p. 127 121. Analgesic Effect of Breast Milk Versus Sucrose for Analgesia During Heel Lance in Late Preterm Infants - p. 128 122. Oral Sucrose and “Facilitated Tucking” for Repeated Pain Relief in Preterms: A Randomized Controlled Trial - p. 129 123. Rapid Sequence Induction is Superior to Morphine for Intubation of Preterm Infants: A Randomized Controlled Trial - p. 130 124. Efficacy of tramadol versus fentanyl for postoperative analgesia in neonates - p. 131 125. Enteral feeding practices in very preterm infants: an international survey - p. 132 126. The Effect of the Odor of Breast Milk on the Time Needed for Transition From Gavage to Total Oral Feeding in Preterm Infants - p. 133 127. Enteral feeding practices in very preterm infants: an international survey - p. 134 128. Impact of Early and High Amino Acid Supplementation on ELBW Infants at 2 Years - p. 135 129. Impact of Early and High Amino Acid Supplementation on ELBW Infants at 2 Years - p. 136 130. Impact of Personalized Feeding Program in 100 NICU Infants: Pathophysiology-based Approach for Better Outcomes - p. 137 131. Impact of Personalized Feeding Program in 100 NICU Infants: Pathophysiology-based Approach for Better Outcomes - p. 138 132. Pediatricians’, Obstetricians’, Gynecologists’, and Family Medicine Physicians’ Experiences with and Attitudes about Breast-Feeding - p. 139 133. Should the use of probiotics in the preterm be routine? - p. 140 134. Should the use of probiotics in the preterm be routine? - p. 141 135. Bifidobacterium septicaemia in an extremely low-birthweight infant under probiotic therapy - p. 142 136. The Human Microbiome and Its Potential Importance to Pediatrics - p. 143 137. Incidence and Timing of Presentation of Necrotizing Enterocolitis in Preterm Infants - p. 144 138. Investigation of the early intestinal microflora in premature infants with/without necrotizing enterocolitis using two different methods - p. 145 139. Risk of Intussusception Following Administration of a Pentavalent Rotavirus Vaccine in US Infants - p. 146 140. The early programming of metabolic health: is epigenetic setting the missing link? - p. 147 141. Why Feed Breast Milk From a Bottle? - p. 148 142. Functional Impairments at School Age of Children With Necrotizing Enterocolitis or Spontaneous Intestinal Perforation - p. 149 143. Comparison of the efficacy of serum amyloid A, C-reactive protein, and procalcitonin in the diagnosis and follow-up of necrotizing enterocolitis in premature infants - p. 150 144. Changes in immunomodulatory constituents of human milk in response to active infection in the nursing infant - p. 151 145. Antibiotic Exposure in the Newborn Intensive Care Unit and the Risk of Necrotizing Enterocolitis - p. 152 146. Absence of gastrointestinal pathogens in ileum tissue resected for necrotizing enterocolitis - p. 153 147. Late-type vitamin K deficiency bleeding: experience from 120 patients - p. 154 148. Economic evaluation alongside the Premature Infants in Need of Transfusion randomised controlled trial - p. 155 149. Acute physiological effects of packed red blood cell transfusion in preterm infants with different degrees of anaemia - p. 156 150. Furosemide for Packed Red Cell Transfusion in Preterm Infants: A Randomized Controlled Trial - p. 157 151. Understanding and managing breast milk jaundice - p. 158 152. Tight Glycemic Control With Insulin in Hyperglycemic Preterm Babies: A Randomized Controlled Trial - p. 159 153. Tight Glycemic Control With Insulin in Hyperglycemic Preterm Babies: A Randomized Controlled Trial - p. 160 154. Tight Glycemic Control With Insulin in Hyperglycemic Preterm Babies: A Randomized Controlled Trial - p. 161 155. Association Between Hospital Recognition for Nursing Excellence and Outcomes of Very Low-Birth-Weight Infants - p. 162 156. Association Between Hospital Recognition for Nursing Excellence and Outcomes of Very Low-Birth-Weight Infants - p. 163 157. Challenges in Setting Up Pediatric and Neonatal Intensive Care Units in a Resource-Limited Country - p. 164 158. Combining Kangaroo Care and Live Harp Music Therapy in the Neonatal Intensive Care Unit Setting - p. 165 159. Factors associated with rehospitalizations of very low birthweight infants: Impact of a transition home support and education program - p. 166 160. Malpractice Risk According to Physician Specialty - p. 167 161. Mandibular Distraction Osteogenesis in Infants Younger Than 3 Months - p. 168 162. Neonatal Abstinence Syndrome and Associated Health Care Expenditures: United States, 2000-2009 - p. 169 163. Neonatal Abstinence Syndrome and Associated Health Care Expenditures: United States, 2000-2009 - p. 170 164. Neonatal intensive care unit safety culture varies widely - p. 171 165. NICU Care in the Aftermath of Hurricane Katrina: 5 Years of Changes - p. 172 166. Parental psychological well-being and cognitive development of very low birth weight infants at 2 years - p. 174 167. Patient Safety in the Context of Neonatal Intensive Care: Research and Educational Opportunities - p. 175 168. Preterm Birth and Psychiatric Disorders in Young Adult Life - p. 176 169. The effect of music-based listening interventions on the volume, fat content, and caloric content of breast milk-produced by mothers of premature and critically ill infants - p. 177 170. The prognostic value of initial blood lactate concentration measurements in very low birthweight infants and their use in development of a new disease severity scoring system - p. 178 171. The single-patient room in the NICU: maternal and family effects - p. 179 172. When Bad Things Happen: Adverse Event Reporting and Disclosure as Patient Safety and Risk Management Tools in the Neonatal Intensive Care Unit - p. 180 173. Enrollment of Extremely Low Birth Weight Infants in a Clinical Research Study May Not Be Representative - p. 181 174. Enrollment of Extremely Low Birth Weight Infants in a Clinical Research Study May Not Be Representative - p. 182 175. Are Proton Pump Inhibitors Safe during Pregnancy and Lactation? Evidence to Date - p. 183 176. Medication Safety in Neonates - p. 184 177. Ranitidine is Associated With Infections, Necrotizing Enterocolitis, and Fatal Outcome in Newborns - p. 185 178. Ranitidine is Associated With Infections, Necrotizing Enterocolitis, and Fatal Outcome in Newborns - p. 186 179. Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity - p. 187 180. Early Nutrition Mediates the Influence of Severity of Illness on Extremely LBW Infants - p. 188 181. Impact of Delivery Room Resuscitation on Outcomes up to 18 Months in Very Low Birth Weight Infants - p. 189 182. Intraventricular Hemorrhage and Developmental Outcomes at 24 Months of Age in Extremely Preterm Infants - p. 190 183. Early postnatal hypotension and developmental delay at 24 months of age among extremely low gestational age newborns - p. 191 184. Early term and late preterm birth are associated with poorer school performance at age 5 years: a cohort study - p. 192 185. Prediction of outcome at 5 years from assessments at 2 years among extremely preterm children: A Norwegian national cohort study - p. 193 186. Stability of Cognitive Outcome From 2 to 5 Years of Age in Very Low Birth Weight Children - p. 194 187. High Blood Pressure in 2.5-Year-Old Children Born Extremely Preterm - p. 195 188. Outcome of Extremely Low Birth Weight Infants Who Received Delivery Room Cardiopulmonary Resuscitation - p. 196 189. Outcome of Extremely Preterm Infants (<1,000 g) With Congenital Heart Defects From the National Institute of Child Health and Human Development Neonatal Research Network - p. 197 190. Outcomes at 7 years for babies who developed neonatal necrotising enterocolitis: the ORACLE Children Study - p. 198 191. Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity - p. 199 192. Breastfeeding, Long-Chain Polyunsaturated Fatty Acids in Colostrum, and Infant Mental Development - p. 200 193. Does maternal depression predict developmental outcome in 18 month old infants? - p. 201 194. The effects of giving pacifiers to premature infants and making them listen to lullabies on their transition period for total oral feeding and sucking success - p. 202 195. Changing long-term outcomes for infants 500–999 g birth weight in Victoria, 1979–2005 - p. 203 196. Changing long-term outcomes for infants 500–999 g birth weight in Victoria, 1979–2005 - p. 204 197. Aberrant Adiposity and Ectopic Lipid Deposition Characterize the Adult Phenotype of the Preterm Infant - p. 205 198. The ethics of obtaining consent in labour for research - p. 206 199. The Prediction and Cost of Futility in the NICU - p. 207 200. How Infants Die in the Neonatal Intensive Care Unit: Trends From 1999 Through 2008 - p. 208 201. Evidence to Inform Decisions About Maternal–Fetal Surgery: Technical Brief - p. 209
The Year Book of Neonatal and Perinatal Medicine brings you abstracts of the articles that reported the year's breakthrough developments in neonatal and perinatal medicine, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! Chapters in this annual cover the most current information on all aspects of neonatal and perinatal medicine from genetics to labor and delivery to issues related to many key bodily systems (heart, respiratory, nervous system, etc.) of newborns. Other topics for 2004 include neurology, gastroenterology and nutrition, medical disorders of pregnancy, fetal evaluation, and neonatal behavior.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Fetal Laboratory Medicine: On the Frontier of Maternal–Fetal Medicine - p. 8 5. Reproductive Technologies and the Risk of Birth Defects - p. 9 6. Placental pathology in asphyxiated newborns meeting the criteria for therapeutic hypothermia - p. 10 7. Accuracy of imaging parameters in the prediction of lethal pulmonary hypoplasia secondary to mid-trimester prelabor rupture of fetal membranes: a systematic review and meta-analysis - p. 11 8. Outcome of fetal exomphalos diagnosed at 11–14 weeks of gestation - p. 12 9. Antenatal Corticosteroids Promote Survival of Extremely Preterm Infants Born at 22 to 23 Weeks of Gestation - p. 13 10. Association of Antenatal Corticosteroids With Mortality and Neurodevelopmental Outcomes Among Infants Born at 22 to 25 Weeks’ Gestation - p. 14 11. Association of Antenatal Corticosteroids With Mortality and Neurodevelopmental Outcomes Among Infants Born at 22 to 25 Weeks' Gestation - p. 15 12. Magnesium sulfate therapy for the prevention of cerebral palsy in preterm infants: a decision-analytic and economic analysis - p. 16 13. Improving Quality of Care for Maternal and Newborn Health: Prospective Pilot Study of the WHO Safe Childbirth Checklist Program - p. 17 14. Use of alcohol-free antimicrobial mouth rinse is associated with decreased incidence of preterm birth in a high-risk population - p. 18 15. The Prediction and Cost of Futility in the NICU - p. 19 16. Survival rates in extremely low birthweight infants depend on the denominator: avoiding potential for bias by specifying denominators - p. 20 17. Improving Survival of Extremely Preterm Infants Born Between 22 and 25 Weeks of Gestation - p. 21 18. Effect of Antenatal Corticosteroids on Fetal Growth and Gestational Age at Birth - p. 22 19. Causes of Death Among Stillbirths - p. 23 20. Assessing the Optimal Definition of Oligohydramnios Associated With Adverse Neonatal Outcomes - p. 24 21. Antenatal Steroids for Treatment of Fetal Lung Immaturity After 34 Weeks of Gestation: An Evaluation of Neonatal Outcomes - p. 25 22. Antenatal Steroids for Treatment of Fetal Lung Immaturity After 34 Weeks of Gestation: An Evaluation of Neonatal Outcomes - p. 26 23. Outcome of Extremely Low Birth Weight Infants Who Received Delivery Room Cardiopulmonary Resuscitation - p. 27 24. Gestational Age at Birth and Mortality in Young Adulthood - p. 28 25. Prenatal environmental risk factors for genital malformations in a population of 1442 French male newborns: a nested case–control study - p. 29 26. Brain anomalies in children exposed prenatally to a common organophosphate pesticide - p. 30 27. Complete Screening of 50 Patients with CHARGE Syndrome for Anomalies in the CHD7 Gene Using a Denaturing High-Performance Liquid Chromatography–Based Protocol: New Guidelines and a Proposal for Routine Diagnosis - p. 31 28. Ichthyosis prematurity syndrome: Clinical evaluation of 17 families with a rare disorder of lipid metabolism - p. 32 29. Effectiveness of pulse oximetry versus fetal electrocardiography for the intrapartum evaluation of nonreassuring fetal heart rate - p. 33 30. Diversity of microbes in amniotic fluid - p. 34 31. Neonatal Outcomes After Implementation of Guidelines Limiting Elective Delivery Before 39 Weeks of Gestation - p. 35 32. Maternal and perinatal complications by day of gestation after spontaneous labor at 40–42 weeks of gestation - p. 36 33. Effect of delayed versus early umbilical cord clamping on neonatal outcomes and iron status at 4 months: a randomised controlled trial - p. 37 34. Uterine Rupture With Attempted Vaginal Birth After Cesarean Delivery: Decision-to-Delivery Time and Neonatal Outcome - p. 38 35. Intrapartum Temperature Elevation, Epidural Use, and Adverse Outcome in Term Infants - p. 39 36. Trends and Characteristics of Home Vaginal Birth After Cesarean Delivery in the United States and Selected States - p. 40 37. Changes in labor patterns over 50 years - p. 41 38. Estimating the Probability of Neonatal Early-Onset Infection on the Basis of Maternal Risk Factors - p. 42 39. The Burden of Invasive Early-onset Neonatal Sepsis in the United States, 2005–2008 - p. 43 40. Cytokine screening identifies NICU patients with Gram-negative bacteremia - p. 44 41. Mortality Reduction by Heart Rate Characteristic Monitoring in Very Low Birth Weight Neonates: A Randomized Trial - p. 45 42. Fluconazole Prophylaxis in Extremely Low Birth Weight Infants and Neurodevelopmental Outcomes and Quality of Life at 8 to 10 Years of Age - p. 46 43. Ohio Statewide Quality-Improvement Collaborative to Reduce Late-Onset Sepsis in Preterm Infants - p. 47 44. Prolonged Initial Empirical Antibiotic Treatment is Associated with Adverse Outcomes in Premature Infants - p. 48 45. Relationship Between Maternal and Neonatal Staphylococcus aureus Colonization - p. 49 46. Topical application of chlorhexidine to neonatal umbilical cords for prevention of omphalitis and neonatal mortality in a rural district of Pakistan: a community-based, cluster-randomised trial - p. 50 47. Treatment of Neonatal Sepsis with Intravenous Immune Globulin - p. 51 48. Treatment of Neonatal Sepsis with Intravenous Immune Globulin - p. 52 49. Treatment of Neonatal Sepsis with Intravenous Immune Globulin - p. 53 50. Oral Acyclovir Suppression and Neurodevelopment after Neonatal Herpes - p. 54 51. Oral Acyclovir Suppression and Neurodevelopment after Neonatal Herpes - p. 55 52. Long-term outcome in preterm children with human cytomegalovirus infection transmitted via breast milk - p. 56 53. Association of Prenatal and Postnatal Exposure to Lopinavir-Ritonavir and Adrenal Dysfunction Among Uninfected Infants of HIV-Infected Mothers - p. 57 54. Antibiotic Exposure in the Newborn Intensive Care Unit and the Risk of Necrotizing Enterocolitis - p. 58 55. Saliva Polymerase-Chain-Reaction Assay for Cytomegalovirus Screening in Newborns - p. 59 56. Unrecognized Ingestion of Toxoplasma gondii Oocysts Leads to Congenital Toxoplasmosis and Causes Epidemics in North America - p. 60 57. The long quest for neonatal screening for severe combined immunodeficiency - p. 61 58. Effect of a partially hydrolyzed whey infant formula at weaning on risk of allergic disease in high-risk children: A randomized controlled trial - p. 62 59. Birth Prevalence of Congenital Heart Disease Worldwide: A Systematic Review and Meta-Analysis - p. 63 60. Strategies for Implementing Screening for Critical Congenital Heart Disease - p. 64 61. Targeted Neonatal Echocardiography in the Neonatal Intensive Care Unit: Practice Guidelines and Recommendations for Training: Writing group of the American Society of Echocardiography (ASE) in collaboration with the European Association of Echocardiography (EAE) and the Association for European Pediatric Cardiologists (AEPC) - p. 65 62. Cardiac biomarkers in neonatal hypoxic ischaemia - p. 68 63. B-Type Natriuretic Peptide and Rebound during Treatment for Persistent Pulmonary Hypertension - p. 69 64. Effect of persistent patent ductus arteriosus on mortality and morbidity in very low-birthweight infants - p. 70 65. Selective serotonin reuptake inhibitors during pregnancy and risk of persistent pulmonary hypertension in the newborn: population based cohort study from the five Nordic countries - p. 71 66. Isolated Atrioventricular Block in the Fetus: A Retrospective, Multinational, Multicenter Study of 175 Patients - p. 72 67. Early postnatal hypotension and developmental delay at 24 months of age among extremely low gestational age newborns - p. 73 68. The right ventricular systolic to diastolic duration ratio: a simple prognostic marker in congenital diaphragmatic hernia? - p. 74 69. Which inotrope and when in neonatal and paediatric intensive care? - p. 75 70. Very low-birth-weight infants with congenital cardiac lesions: Is there merit in delaying intervention to permit growth and maturation? - p. 77 71. Complications After the Norwood Operation: An Analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database - p. 78 72. Randomized Controlled Trial of Restrictive Fluid Management in Transient Tachypnea of the Newborn - p. 79 73. Surfactant Deficiency in Transient Tachypnea of the Newborn - p. 80 74. Randomized Trial Comparing 3 Approaches to the Initial Respiratory Management of Preterm Neonates - p. 81 75. Randomized Trial Comparing 3 Approaches to the Initial Respiratory Management of Preterm Neonates - p. 82 76. Avoidance of mechanical ventilation by surfactant treatment of spontaneously breathing preterm infants (AMV): an open-label, randomised, controlled trial - p. 83 77. Mortality in preterm infants with respiratory distress syndrome treated with poractant alfa, calfactant or beractant: a retrospective study - p. 84 78. Preliminary evaluation of a new technique of minimally invasive surfactant therapy - p. 85 79. Mortality in preterm infants with respiratory distress syndrome treated with poractant alfa, calfactant or beractant: a retrospective study - p. 86 80. Nasal Continuous Positive Airway Pressure With Heliox in Preterm Infants With Respiratory Distress Syndrome - p. 87 81. Positive effects of early continuous positive airway pressure on pulmonary function in extremely premature infants: results of a subgroup analysis of the COIN trial - p. 88 82. Predictors of early nasal CPAP failure and effects of various intubation criteria on the rate of mechanical ventilation in preterm infants of <29 weeks gestational age - p. 89 83. Early prediction of nasal continuous positive airway pressure failure in preterm infants less than 30 weeks gestation - p. 90 84. Prediction of Bronchopulmonary Dysplasia by Postnatal Age in Extremely Premature Infants - p. 91 85. Clarithromycin in Preventing Bronchopulmonary Dysplasia in Ureaplasma urealyticum–Positive Preterm Infants - p. 92 86. Clarithromycin in Preventing Bronchopulmonary Dysplasia in Ureaplasma urealyticum–Positive Preterm Infants - p. 93 87. Molecular Identification of Bacteria in Tracheal Aspirate Fluid from Mechanically Ventilated Preterm Infants - p. 94 88. A new method for continuous monitoring of chest wall movement to characterize hypoxemic episodes during HFOV - p. 95 89. Airway obstruction and gas leak during mask ventilation of preterm infants in the delivery room - p. 96 90. Mask leak in one-person mask ventilation compared to two-person in newborn infant manikin study - p. 97 91. Hospital Variation in Nitric Oxide Use for Premature Infants - p. 98 92. Inhaled Nitric Oxide in Preterm Infants: An Individual-Patient Data Meta-analysis of Randomized Trials - p. 99 93. Protocolized management of infants with congenital diaphragmatic hernia: effect on survival - p. 100 94. Application of Criteria Developed by the Task Force on Neonatal Encephalopathy and Cerebral Palsy to Acutely Asphyxiated Neonates - p. 101 95. Childhood Outcomes after Hypothermia for Neonatal Encephalopathy - p. 102 96. Childhood Outcomes after Hypothermia for Neonatal Encephalopathy - p. 103 97. Long-term neuroprotective effects of allopurinol after moderate perinatal asphyxia: follow-up of two randomised controlled trials - p. 104 98. Long-term neuroprotective effects of allopurinol after moderate perinatal asphyxia: follow-up of two randomised controlled trials - p. 105 99. Seven- to eight-year follow-up of the CoolCap trial of head cooling for neonatal encephalopathy - p. 106 100. Xenon Augmented Hypothermia Reduces Early Lactate/N-Acetylaspartate and Cell Death in Perinatal Asphyxia - p. 107 101. The effect of whole-body cooling on brain metabolism following perinatal hypoxic–ischemic injury - p. 108 102. Distribution and severity of hypoxic–ischaemic lesions on brain MRI following therapeutic cooling: selective head versus whole body cooling - p. 109 103. Changes of Positron Emission Tomography in Newborn Infants at Different Gestational Ages, and Neonatal Hypoxic-Ischemic Encephalopathy - p. 110 104. Cytokines and Neurodevelopmental Outcomes in Extremely Low Birth Weight Infants - p. 111 105. Dendrimer-Based Postnatal Therapy for Neuroinflammation and Cerebral Palsy in a Rabbit Model - p. 112 106. DTI reveals network injury in perinatal stroke - p. 113 107. Symptomatic Neonatal Arterial Ischemic Stroke: The International Pediatric Stroke Study - p. 114 108. Effects of Prone and Supine Position on Cerebral Blood Flow in Preterm Infants - p. 115 109. Recording conventional and amplitude-integrated EEG in neonatal intensive care unit - p. 116 110. Impact of Amplitude-Integrated Electroencephalograms on Clinical Care for Neonates With Seizures - p. 117 111. Neonatal Seizures: Treatment Practices Among Term and Preterm Infants - p. 118 112. Grade and laterality of intraventricular haemorrhage to predict 18–22 month neurodevelopmental outcomes in extremely low birthweight infants - p. 119 113. Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity - p. 120 114. Neurologic Outcomes in Very Preterm Infants Undergoing Surgery - p. 121 115. Neonatal Intensive Care Unit Stress Is Associated with Brain Development in Preterm Infants - p. 122 116. Infant regulation of intake: the effect of free glutamate content in infant formulas - p. 123 117. Effects of fetal antiepileptic drug exposure: Outcomes at age 4.5 years - p. 124 118. Normal gut microbiota modulates brain development and behavior - p. 125 119. Current Role of Cryotherapy in Retinopathy of Prematurity: A Report by the American Academy of Ophthalmology - p. 126 120. Association of Antenatal Corticosteroids With Mortality and Neurodevelopmental Outcomes Among Infants Born at 22 to 25 Weeks’ Gestation - p. 127 121. Analgesic Effect of Breast Milk Versus Sucrose for Analgesia During Heel Lance in Late Preterm Infants - p. 128 122. Oral Sucrose and “Facilitated Tucking” for Repeated Pain Relief in Preterms: A Randomized Controlled Trial - p. 129 123. Rapid Sequence Induction is Superior to Morphine for Intubation of Preterm Infants: A Randomized Controlled Trial - p. 130 124. Efficacy of tramadol versus fentanyl for postoperative analgesia in neonates - p. 131 125. Enteral feeding practices in very preterm infants: an international survey - p. 132 126. The Effect of the Odor of Breast Milk on the Time Needed for Transition From Gavage to Total Oral Feeding in Preterm Infants - p. 133 127. Enteral feeding practices in very preterm infants: an international survey - p. 134 128. Impact of Early and High Amino Acid Supplementation on ELBW Infants at 2 Years - p. 135 129. Impact of Early and High Amino Acid Supplementation on ELBW Infants at 2 Years - p. 136 130. Impact of Personalized Feeding Program in 100 NICU Infants: Pathophysiology-based Approach for Better Outcomes - p. 137 131. Impact of Personalized Feeding Program in 100 NICU Infants: Pathophysiology-based Approach for Better Outcomes - p. 138 132. Pediatricians’, Obstetricians’, Gynecologists’, and Family Medicine Physicians’ Experiences with and Attitudes about Breast-Feeding - p. 139 133. Should the use of probiotics in the preterm be routine? - p. 140 134. Should the use of probiotics in the preterm be routine? - p. 141 135. Bifidobacterium septicaemia in an extremely low-birthweight infant under probiotic therapy - p. 142 136. The Human Microbiome and Its Potential Importance to Pediatrics - p. 143 137. Incidence and Timing of Presentation of Necrotizing Enterocolitis in Preterm Infants - p. 144 138. Investigation of the early intestinal microflora in premature infants with/without necrotizing enterocolitis using two different methods - p. 145 139. Risk of Intussusception Following Administration of a Pentavalent Rotavirus Vaccine in US Infants - p. 146 140. The early programming of metabolic health: is epigenetic setting the missing link? - p. 147 141. Why Feed Breast Milk From a Bottle? - p. 148 142. Functional Impairments at School Age of Children With Necrotizing Enterocolitis or Spontaneous Intestinal Perforation - p. 149 143. Comparison of the efficacy of serum amyloid A, C-reactive protein, and procalcitonin in the diagnosis and follow-up of necrotizing enterocolitis in premature infants - p. 150 144. Changes in immunomodulatory constituents of human milk in response to active infection in the nursing infant - p. 151 145. Antibiotic Exposure in the Newborn Intensive Care Unit and the Risk of Necrotizing Enterocolitis - p. 152 146. Absence of gastrointestinal pathogens in ileum tissue resected for necrotizing enterocolitis - p. 153 147. Late-type vitamin K deficiency bleeding: experience from 120 patients - p. 154 148. Economic evaluation alongside the Premature Infants in Need of Transfusion randomised controlled trial - p. 155 149. Acute physiological effects of packed red blood cell transfusion in preterm infants with different degrees of anaemia - p. 156 150. Furosemide for Packed Red Cell Transfusion in Preterm Infants: A Randomized Controlled Trial - p. 157 151. Understanding and managing breast milk jaundice - p. 158 152. Tight Glycemic Control With Insulin in Hyperglycemic Preterm Babies: A Randomized Controlled Trial - p. 159 153. Tight Glycemic Control With Insulin in Hyperglycemic Preterm Babies: A Randomized Controlled Trial - p. 160 154. Tight Glycemic Control With Insulin in Hyperglycemic Preterm Babies: A Randomized Controlled Trial - p. 161 155. Association Between Hospital Recognition for Nursing Excellence and Outcomes of Very Low-Birth-Weight Infants - p. 162 156. Association Between Hospital Recognition for Nursing Excellence and Outcomes of Very Low-Birth-Weight Infants - p. 163 157. Challenges in Setting Up Pediatric and Neonatal Intensive Care Units in a Resource-Limited Country - p. 164 158. Combining Kangaroo Care and Live Harp Music Therapy in the Neonatal Intensive Care Unit Setting - p. 165 159. Factors associated with rehospitalizations of very low birthweight infants: Impact of a transition home support and education program - p. 166 160. Malpractice Risk According to Physician Specialty - p. 167 161. Mandibular Distraction Osteogenesis in Infants Younger Than 3 Months - p. 168 162. Neonatal Abstinence Syndrome and Associated Health Care Expenditures: United States, 2000-2009 - p. 169 163. Neonatal Abstinence Syndrome and Associated Health Care Expenditures: United States, 2000-2009 - p. 170 164. Neonatal intensive care unit safety culture varies widely - p. 171 165. NICU Care in the Aftermath of Hurricane Katrina: 5 Years of Changes - p. 172 166. Parental psychological well-being and cognitive development of very low birth weight infants at 2 years - p. 174 167. Patient Safety in the Context of Neonatal Intensive Care: Research and Educational Opportunities - p. 175 168. Preterm Birth and Psychiatric Disorders in Young Adult Life - p. 176 169. The effect of music-based listening interventions on the volume, fat content, and caloric content of breast milk-produced by mothers of premature and critically ill infants - p. 177 170. The prognostic value of initial blood lactate concentration measurements in very low birthweight infants and their use in development of a new disease severity scoring system - p. 178 171. The single-patient room in the NICU: maternal and family effects - p. 179 172. When Bad Things Happen: Adverse Event Reporting and Disclosure as Patient Safety and Risk Management Tools in the Neonatal Intensive Care Unit - p. 180 173. Enrollment of Extremely Low Birth Weight Infants in a Clinical Research Study May Not Be Representative - p. 181 174. Enrollment of Extremely Low Birth Weight Infants in a Clinical Research Study May Not Be Representative - p. 182 175. Are Proton Pump Inhibitors Safe during Pregnancy and Lactation? Evidence to Date - p. 183 176. Medication Safety in Neonates - p. 184 177. Ranitidine is Associated With Infections, Necrotizing Enterocolitis, and Fatal Outcome in Newborns - p. 185 178. Ranitidine is Associated With Infections, Necrotizing Enterocolitis, and Fatal Outcome in Newborns - p. 186 179. Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity - p. 187 180. Early Nutrition Mediates the Influence of Severity of Illness on Extremely LBW Infants - p. 188 181. Impact of Delivery Room Resuscitation on Outcomes up to 18 Months in Very Low Birth Weight Infants - p. 189 182. Intraventricular Hemorrhage and Developmental Outcomes at 24 Months of Age in Extremely Preterm Infants - p. 190 183. Early postnatal hypotension and developmental delay at 24 months of age among extremely low gestational age newborns - p. 191 184. Early term and late preterm birth are associated with poorer school performance at age 5 years: a cohort study - p. 192 185. Prediction of outcome at 5 years from assessments at 2 years among extremely preterm children: A Norwegian national cohort study - p. 193 186. Stability of Cognitive Outcome From 2 to 5 Years of Age in Very Low Birth Weight Children - p. 194 187. High Blood Pressure in 2.5-Year-Old Children Born Extremely Preterm - p. 195 188. Outcome of Extremely Low Birth Weight Infants Who Received Delivery Room Cardiopulmonary Resuscitation - p. 196 189. Outcome of Extremely Preterm Infants (<1,000 g) With Congenital Heart Defects From the National Institute of Child Health and Human Development Neonatal Research Network - p. 197 190. Outcomes at 7 years for babies who developed neonatal necrotising enterocolitis: the ORACLE Children Study - p. 198 191. Survival Without Disability to Age 5 Years After Neonatal Caffeine Therapy for Apnea of Prematurity - p. 199 192. Breastfeeding, Long-Chain Polyunsaturated Fatty Acids in Colostrum, and Infant Mental Development - p. 200 193. Does maternal depression predict developmental outcome in 18 month old infants? - p. 201 194. The effects of giving pacifiers to premature infants and making them listen to lullabies on their transition period for total oral feeding and sucking success - p. 202 195. Changing long-term outcomes for infants 500–999 g birth weight in Victoria, 1979–2005 - p. 203 196. Changing long-term outcomes for infants 500–999 g birth weight in Victoria, 1979–2005 - p. 204 197. Aberrant Adiposity and Ectopic Lipid Deposition Characterize the Adult Phenotype of the Preterm Infant - p. 205 198. The ethics of obtaining consent in labour for research - p. 206 199. The Prediction and Cost of Futility in the NICU - p. 207 200. How Infants Die in the Neonatal Intensive Care Unit: Trends From 1999 Through 2008 - p. 208 201. Evidence to Inform Decisions About Maternal–Fetal Surgery: Technical Brief - p. 209