The Year Book of Neurology and Neurosurgery brings you abstracts of the articles that reported the year's breakthrough developments in neurology and neurosurgery, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! Readers will find information on a range of topics, including Movement Disorders, Infectious Diseases of the Nervous System, Neoplastic Disease, Pediatric Neurology and Neurosurgery, Cerebrovascular, Neuro-oncology, and Spine. The Year Book of Neurology and Neurosurgery is published annually in June.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Epilepsy and Other Seizure Disorders - p. 8 5. A rapid course through the five electrographic stages of status epilepticus - p. 9 6. Alcohol and drugs in epilepsy: Pathophysiology, presentation, possibilities, and prevention - p. 10 7. Advanced Treatments for Childhood Epilepsy: Beyond Antiseizure Medications - p. 11 8. Dilemmas in the interpretation of diagnostic accuracy studies on presurgical workup for epilepsy surgery - p. 12 9. Diagnosis and management of the epilepsies in children: a summary of the partial update of the 2012 NICE epilepsy guideline - p. 13 10. Epileptic encephalopathies (including severe epilepsy syndromes) - p. 14 11. Antiepileptic Drugs 2012: Recent Advances and Trends - p. 15 12. Benign childhood focal epilepsies - p. 16 13. Antiglutamic Acid Decarboxylase Antibodies in Children With Encephalitis and Status Epilepticus - p. 17 14. Cardiac autonomic dysfunction in drug naïve hot water epilepsy - p. 18 15. Dramatic weight loss with rufinamide - p. 19 16. A randomized controlled trial of flunarizine as add-on therapy and effect on cognitive outcome in children with infantile spasms - p. 20 17. Acute EEG findings in children with febrile status epilepticus: Results of the FEBSTAT study - p. 21 18. Lamotrigine Serum Concentration in Children With Epilepsy - p. 22 19. Feasibility of antiepileptic drug withdrawal following extratemporal resective epilepsy surgery - p. 23 20. Clinical outcomes, quality of life, and costs associated with implantation of vagus nerve stimulation therapy in pediatric patients with drug-resistant epilepsy - p. 24 21. Aggressive behavior and epilepsy: A multicenter study - p. 25 22. Headache - p. 26 23. Thunderclap headache - p. 27 24. Advances in Drug Development for Acute Migraine - p. 28 25. Improvement in Headaches With Continuous Positive Airway Pressure for Obstructive Sleep Apnea: A Retrospective Analysis - p. 29 26. Treatment of Pediatric Migraine in the Emergency Room - p. 30 27. Resident and Fellow Section - p. 31 28. Unusual Headache Syndromes - p. 32 29. Her versus his migraine: multiple sex differences in brain function and structure - p. 33 30. Bilateral acute angle-closure glaucoma in a migraine patient receiving topiramate: a case report - p. 34 31. Obese children suffer more often from migraine - p. 35 32. Frequency and Burden of Headache-Related Nausea: Results From the American Migraine Prevalence and Prevention (AMPP) Study - p. 36 33. The syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis (HaNDL) as an acute ischemic stroke mimic leading to systemic thrombolysis: A case report - p. 37 34. LASH Syndrome: A Third Reported Case Twelve Years After the First - p. 38 35. Does Health Information Exchange Reduce Unnecessary Neuroimaging and Improve Quality of Headache Care in the Emergency Department? - p. 39 36. Dry Eyes and Migraines: Is There Really a Correlation? - p. 40 37. Pediatric Posttraumatic Headache: Two Cases Using Steroids as Abortive Therapy - p. 41 38. Infectious Diseases of the Nervous System - p. 42 39. Ultrasound study shows nerve atrophy in post herpetic neuralgia - p. 43 40. Case 1-2013: A 63-Year-Old Man with Paresthesias and Difficulty Swallowing - p. 44 41. Varicella-zoster virus encephalitis and vasculopathy in a patient treated with fingolimod - p. 45 42. Steroids and Childhood Encephalitis - p. 46 43. Iatrogenic prion diseases in humans: an update - p. 47 44. Seizures and encephalitis: Clinical features, management, and potential pathophysiologic mechanisms - p. 48 45. The Index Case for the Fungal Meningitis Outbreak in the United States - p. 49 46. Nationwide survey of patients in Japan with Bickerstaff brainstem encephalitis: epidemiological and clinical characteristics - p. 50 47. Locally acquired West Nile encephalitis - p. 51 48. Advances in treatment of bacterial meningitis - p. 52 49. Acute meningitis prognosis using cerebrospinal fluid interleukin-6 levels - p. 53 50. Dilemmas in the diagnosis of acute community-acquired bacterial meningitis - p. 54 51. A comparison of tau and 14-3-3 protein in the diagnosis of Creutzfeldt-Jakob disease - p. 55 52. Extreme delta brush: A unique EEG pattern in adults with anti-NMDA receptor encephalitis - p. 56 53. A Life-Threatening Central Nervous System–Tuberculosis Inflammatory Reaction Nonresponsive to Corticosteroids and Successfully Controlled by Infliximab in a Young Patient With a Variant of Juvenile Idiopathic Arthritis - p. 57 54. Movement Disorders - p. 58 55. Clinical features of dopamine agonist withdrawal syndrome in a movement disorders clinic - p. 59 56. Clinical subtypes of anterocollis in parkinsonian syndromes - p. 60 57. Accuracy of a Panel of 5 Cerebrospinal Fluid Biomarkers in the Differential Diagnosis of Patients With Dementia and/or Parkinsonian Disorders - p. 61 58. Cerebral pathological and compensatory mechanisms in the premotor phase of leucine-rich repeat kinase 2 parkinsonism - p. 62 59. Neurologist-associated reduction in PD-related hospitalizations and health care expenditures - p. 63 60. Risk factors for freezing of gait in Parkinson's disease - p. 64 61. Treatment patterns and associated costs with Parkinson's disease levodopa induced dyskinesia - p. 65 62. Anti-cholinergics for axial symptoms in Parkinson's disease after subthalamic stimulation - p. 66 63. Musculoskeletal problems as an initial manifestation of Parkinson's disease: A retrospective study - p. 67 64. Randomized clinical trial of fipamezole for dyskinesia in Parkinson disease (FJORD study) - p. 68 65. Comparison of patient rated treatment response with measured improvement in Parkinson's disease - p. 69 66. A randomized, double-blind, placebo-controlled trial of antidepressants in Parkinson disease - p. 70 67. Randomized trial of deep brain stimulation for Parkinson disease: Thirty-six-month outcomes - p. 71 68. Placebo-controlled trial of lubiprostone for constipation associated with Parkinson disease - p. 72 69. Worsening essential tremor following deep brain stimulation: disease progression versus tolerance - p. 73 70. Multiple Sclerosis and Other Demyelinating Diseases - p. 74 71. “Undiagnosing” multiple sclerosis: the challenge of misdiagnosis in MS - p. 75 72. Fatigue in multiple sclerosis – A brief review - p. 76 73. Low vitamin D and elevated immunoreactivity against Epstein–Barr virus before first clinical manifestation of multiple sclerosis - p. 77 74. Disease-modifying drugs for multiple sclerosis in pregnancy: A systematic review - p. 78 75. Distinct lesion morphology at 7-T MRI differentiates neuromyelitis optica from multiple sclerosis - p. 79 76. Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial - p. 80 77. The cervical spinal cord in neuromyelitis optica patients: A comparative study with multiple sclerosis using diffusion tensor imaging - p. 81 78. Decreased Frontal Lobe Gray Matter Perfusion in Cognitively Impaired Patients with Secondary-Progressive Multiple Sclerosis Detected by the Bookend Technique - p. 82 79. Effect of Aquatic Exercise Training on Fatigue and Health-Related Quality of Life in Patients With Multiple Sclerosis - p. 83 80. Heterogeneity of cortical lesions in multiple sclerosis: Clinical and pathologic implications - p. 84 81. Gray Matter Pathology in MS: A 3-Year Longitudinal Study in a Pediatric Population - p. 85 82. Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis - p. 86 83. Cortical lesion load associates with progression of disability in multiple sclerosis - p. 87 84. Impact of Fingolimod Therapy on Magnetic Resonance Imaging Outcomes in Patients With Multiple Sclerosis - p. 88 85. Ginkgo biloba does not improve cognitive function in MS: A randomized placebo-controlled trial - p. 89 86. Neoplastic Disease - p. 90 87. Refractory temporal lobe epilepsy caused by angiocentric glioma complicated with focal cortical dysplasia: a surgical case series - p. 91 88. An experimental study on acute brain radiation injury: Dynamic changes in proton magnetic resonance spectroscopy and the correlation with histopathology - p. 92 89. Differentiation of glioblastoma and primary CNS lymphomas using susceptibility weighted imaging - p. 93 90. Long-term follow-up of vanishing tumors in the brain: How should a lesion mimicking primary CNS lymphoma be managed? - p. 94 91. Diffusion Tensor Imaging Provides an Insight Into the Microstructure of Meningiomas, High-Grade Gliomas, and Peritumoral Edema - p. 95 92. A randomized trial on the efficacy of methylphenidate and modafinil for improving cognitive functioning and symptoms in patients with a primary brain tumor - p. 96 93. Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation - p. 97 94. Risk of ischemia in glioma surgery: comparison of first and repeat procedures - p. 98 95. Differentiation between Brain Glioblastoma Multiforme and Solitary Metastasis: Qualitative and Quantitative Analysis Based on Routine MR Imaging - p. 99 96. Detection of IDH1 mutation in the plasma of patients with glioma - p. 100 97. Correlation between language function and the left arcuate fasciculus detected by diffusion tensor imaging tractography after brain tumor surgery - p. 101 98. Cognitive functioning early after surgery of gliomas in eloquent areas - p. 102 99. Diagnostic performance of whole brain volume perfusion CT in intra-axial brain tumors: Preoperative classification accuracy and histopathologic correlation - p. 103 100. Diffuse brainstem glioma: prognostic factors - p. 104 101. Cranial Irradiation Increases Risk of Stroke in Pediatric Brain Tumor Survivors - p. 105 102. Comparison of a Strategy Favoring Early Surgical Resection vs a Strategy Favoring Watchful Waiting in Low-Grade Gliomas - p. 106 103. Neuromuscular Disease - p. 107 104. Comprehensive analysis of the TRPV4 gene in a large series of inherited neuropathies and controls - p. 108 105. Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice - p. 109 106. Novel mutation in VCP gene causes atypical amyotrophic lateral sclerosis - p. 110 107. GSK3β mediates muscle pathology in myotonic dystrophy - p. 111 108. Dysfunction of the neuromuscular junction in spinal muscular atrophy types 2 and 3 - p. 112 109. Characterization of a Family With c9FTD/ALS Associated With the GGGGCC Repeat Expansion in C9ORF72 - p. 113 110. Myasthenia gravis in the elderly - p. 114 111. Extensive genetics of ALS: A population-based study in Italy - p. 115 112. Reliability and accuracy of skeletal muscle imaging in limb-girdle muscular dystrophies - p. 116 113. Awaji Criteria for the Diagnosis of Amyotrophic Lateral Sclerosis: A Systematic Review - p. 117 114. Neuro-otology - p. 118 115. Recent advances in central acute vestibular syndrome of a vascular cause - p. 119 116. Gamma Knife Treatment of Growing Vestibular Schwannoma in Norway: A Prospective Study - p. 120 117. Current epidemiology and management trends in acoustic neuroma - p. 121 118. Neuroanatomical correlates of tinnitus revealed by cortical thickness analysis and diffusion tensor imaging - p. 122 119. Endolymphatic Space Imaging in Idiopathic Sudden Sensorineural Hearing Loss With Vertigo - p. 123 120. Short-term audiologic effect of intratympanic gadolinium contrast agent application in patients with Ménière's disease - p. 124 121. Audiovestibular Dysfunction Associated with Adoptive Cell Immunotherapy for Melanoma - p. 125 122. Quality of Life of Patients With Bilateral Vestibulopathy - p. 126 123. Traumatic Tympanic Membrane Perforations: Clinical and Audiometric Findings in 198 Patients - p. 127 124. Benign paroxysmal positional vertigo in people with traumatic spinal cord injury: incidence, treatment efficacy and implications - p. 128 125. A Randomized, Double-Blind, Placebo-Controlled Clinical Study to Assess Safety and Clinical Activity of OTO-104 Given as a Single Intratympanic Injection in Patients With Unilateral Ménière's Disease - p. 129 126. Auditory and Vestibular Symptoms and Chronic Subjective Dizziness in Patients With Ménière's Disease, Vestibular Migraine, and Ménière's Disease With Concomitant Vestibular Migraine - p. 130 127. Irreversible Atorvastatin-Associated Hearing Loss - p. 131 128. Tinnitus in Children: Association With Stress and Trait Anxiety - p. 132 129. Risk of Developing Sudden Sensorineural Hearing Loss in Diabetic Patients: A Population-Based Cohort Study - p. 133 130. Pediatric Neurology - p. 134 131. Early-Onset Epileptic Encephalopathies: Ohtahara Syndrome and Early Myoclonic Encephalopathy - p. 135 132. A Randomized, Double-Blind Study of 30 Versus 20 mg Dexmethylphenidate Extended-Release in Children With Attention-Deficit/Hyperactivity Disorder: Late-Day Symptom Control - p. 136 133. Glucose transporter type I deficiency syndrome: Epilepsy phenotypes and outcomes - p. 137 134. Does a Normalizing Electroencephalogram in Benign Childhood Epilepsy with Centrotemporal Spikes Abort Attention Deficit Hyperactivity Disorder? - p. 138 135. Fever and fever-related epilepsies - p. 139 136. Sleep Disorders - p. 140 137. Society for Ambulatory Anesthesia Consensus Statement on Preoperative Selection of Adult Patients With Obstructive Sleep Apnea Scheduled for Ambulatory Surgery - p. 141 138. Characteristics of refractory vs. medically controlled epilepsy patients with obstructive sleep apnea and their response to CPAP treatment - p. 142 139. The impact of epilepsy on sleep architecture during childhood - p. 143 140. Effect of Continuous Positive Airway Pressure on the Incidence of Hypertension and Cardiovascular Events in Nonsleepy Patients With Obstructive Sleep Apnea: A Randomized Controlled Trial - p. 144 141. Association of Sleep-Disordered Breathing With Cognitive Dysfunction in CKD Stages 4-5 - p. 145 142. Effect of Continuous Positive Airway Pressure Therapy on Cardiovascular Risk Factors in Patients with Type 2 Diabetes and Obstructive Sleep Apnea - p. 146 143. Effect of Continuous Positive Airway Pressure on C-reactive Protein Levels in Sleep Apnea: A Meta-analysis - p. 147 144. Sleep-disordered breathing in multiple sclerosis - p. 148 145. Effects of Continuous Positive Airway Pressure on Neurocognitive Function in Obstructive Sleep Apnea Patients: The Apnea Positive Pressure Long-Term Efficacy Study (APPLES) - p. 149 146. Adaptive Servoventilation for Treatment of Sleep-Disordered Breathing in Heart Failure: A Systematic Review and Meta-Analysis - p. 150 147. Cardiovascular Mortality in Obstructive Sleep Apnea in the Elderly: Role of Long-Term Continuous Positive Airway Pressure Treatment: A Prospective Observational Study - p. 151 148. Utility of overnight pulse oximetry and heart rate variability analysis to screen for sleep-disordered breathing in chronic heart failure - p. 152 149. The Associations of Insomnia With Costly Workplace Accidents and Errors: Results From the America Insomnia Survey - p. 153 150. Association of Insomnia and Short Sleep Duration With Atherosclerosis Risk in the Elderly - p. 154 151. Sleep-disordered Breathing and Cancer Mortality: Results from the Wisconsin Sleep Cohort Study - p. 155 152. Association of multiple sclerosis with restless legs syndrome and other sleep disorders in women - p. 156 153. Miscellaneous - p. 157 154. American Medical Society for Sports Medicine Position Statement: Concussion in Sport - p. 158 155. Advances in stem cell therapy for spinal cord injury - p. 159 156. A pilot study of cerebral and haemodynamic physiological changes during sedation with dexmedetomidine or propofol in patients with acute brain injury - p. 160 157. Complex single gene disorders and epilepsy - p. 161 158. Clinical Applications of Hybrid PET/MRI in Neuroimaging - p. 162 159. Comparative stroke risk of antiepileptic drugs in patients with epilepsy - p. 163 160. Brain Tumors - p. 164 161. Endoscopic endonasal surgery for giant pituitary adenomas: advantages and limitations - p. 165 162. Value of endoscopy for maximizing tumor removal in endonasal transsphenoidal pituitary adenoma surgery - p. 166 163. Hearing preservation in patients with vestibular schwannoma treated with Gamma Knife surgery - p. 167 164. Longitudinal analysis of hearing before and after radiosurgery for vestibular schwannoma - p. 168 165. Long-term hearing outcomes following stereotactic radiosurgery for vestibular schwannoma: patterns of hearing loss and variables influencing audiometric decline - p. 169 166. Long-term safety and efficacy of stereotactic radiosurgery for vestibular schwannomas: evaluation of 440 patients more than 10 years after treatment with Gamma Knife surgery - p. 170 167. Gamma Knife surgery in the treatment paradigm for foramen magnum meningiomas - p. 171 168. Giant anterior clinoidal meningiomas: surgical technique and outcomes - p. 172 169. The role of radiotherapy following gross-total resection of atypical meningiomas - p. 173 170. Cerebral revascularization and carotid artery resection at the skull base for treatment of advanced head and neck malignancies - p. 174 171. Chromosomal alterations, prognostic factors, and targeted molecular therapies for malignant meningiomas - p. 175 172. Ten years of experience with microsurgical treatment of large and giant petroclival meningiomas - p. 176 173. Radiation-induced meningiomas after high-dose cranial irradiation - p. 177 174. The role of radiotherapy following gross-total resection of atypical meningiomas - p. 178 175. Single-Fraction Radiosurgery of Benign Intracranial Meningiomas - p. 179 176. The influence of surgery on quality of life in patients with intracranial meningiomas: a prospective study - p. 180 177. Risk for leptomeningeal seeding after resection for brain metastases: Implication of tumor location with mode of resection - p. 181 178. Systematic review of primary intracranial glioblastoma multiforme with symptomatic spinal metastases, with two illustrative patients - p. 182 179. Retrosigmoid Approach to Cerebellopontine Angle Tumor Resection: Surgical Modifications - p. 183 180. Early rehabilitation after surgery improves functional outcome in inpatients with brain tumours - p. 184 181. Chromosomal anomalies and prognostic markers for intracranial and spinal ependymomas - p. 185 182. Imaging modalities in high-grade gliomas: Pseudoprogression, recurrence, or necrosis? - p. 186 183. Frameless robotically targeted stereotactic brain biopsy: feasibility, diagnostic yield, and safety - p. 187 184. Cerebrovascular - p. 188 185. Long-term Results of Gamma Knife Surgery for Partially Embolized Arteriovenous Malformations - p. 189 186. Validation and absolute quantification of MR perfusion compared with CT perfusion in patients with unilateral cerebral arterial stenosis - p. 190 187. Safety and Efficacy of Intraoperative Angiography in Craniotomies for Cerebral Aneurysms and Arteriovenous Malformations: A Review of 1093 Consecutive Cases - p. 191 188. Solitaire flow restoration device versus the Merci Retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial - p. 192 189. Early Postmarket Results After Treatment of Intracranial Aneurysms With the Pipeline Embolization Device: A US Multicenter Experience - p. 193 190. A Comparison of Radiation Exposure between Diagnostic CTA and DSA Examinations of Cerebral and Cervicocerebral Vessels - p. 194 191. Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke - p. 195 192. Does Stent Implantation Improve the Result of Repeat Embolization in Recanalized Aneurysms? - p. 196 193. Distinctive flow pattern of wall shear stress and oscillatory shear index: similarity and dissimilarity in ruptured and unruptured cerebral aneurysm blebs - p. 197 194. Subarachnoid Hemorrhage Incidence in the United States Does Not Vary with Season or Temperature - p. 198 195. Surgical results of the Carotid Occlusion Surgery Study - p. 199 196. Stroke After Carotid Stenting and Endarterectomy in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) - p. 200 197. Pediatric Neurosurgery - p. 201 198. Craniocervical fusions in children - p. 202 199. Image-guided cerebrospinal fluid shunting in children: catheter accuracy and shunt survival - p. 203 200. Optimal timing of autologous cranioplasty after decompressive craniectomy in children - p. 204 201. Treatment of choroid plexus tumors: a 20-year single institutional experience - p. 205 202. Internal cranial expansion surgery for the treatment of refractory idiopathic intracranial hypertension - p. 206 203. Follow-up imaging to detect recurrence of surgically treated pediatric arteriovenous malformations - p. 207 204. Programmable shunt valve affected by exposure to a tablet computer - p. 208 205. Nonprogrammable and programmable cerebrospinal fluid shunt valves: a 5-year study - p. 209 206. The use of abdominal binders to treat over-shunting headaches - p. 210 207. Choroid plexus coagulation for hydrocephalus not due to CSF overproduction: a review - p. 211 208. Shunt survival after failed endoscopic treatment of hydrocephalus - p. 212 209. Second impact syndrome in football: new imaging and insights into a rare and devastating condition - p. 213 210. Spine - p. 214 211. Interrater and Intrarater Reliability of the Kuntz et al New Deformity Classification System - p. 215 212. Cervical decompression and reconstruction without intraoperative neurophysiological monitoring - p. 216 213. Surgical management of unknown primary tumors metastatic to the spine - p. 217 214. Results and complications after 2-level axial lumbar interbody fusion with a minimum 2-year follow-up - p. 218 215. Unilateral surgical approach for lumbar disc herniation with contralateral symptoms - p. 219 216. Outcomes of instrumented fusion in the pediatric cervical spine - p. 220 217. 2012 Young Investigator Award Winner: The Distribution of Body Mass as a Significant Risk Factor for Lumbar Spinal Fusion Postoperative Infections - p. 221 218. An Injectable Nucleus Pulposus Implant Restores Compressive Range of Motion in the Ovine Disc - p. 222 219. Incidental durotomy after spinal surgery: a prospective study in an academic institution: Presented at the 2012 Joint Spine Section Meeting - p. 223 220. Perioperative and delayed complications associated with the surgical treatment of cervical spondylotic myelopathy based on 302 patients from the AOSpine North America Cervical Spondylotic Myelopathy Study: Presented at the 2011 Spine Section Meeting - p. 224 221. Microscope Sterility During Spine Surgery - p. 225 222. C2 Nerve Root Sectioning in Posterior C1-2 Instrumented Fusions - p. 226 223. Surgical Techniques - p. 227 224. Intradural anterior petrosectomy for petroclival meningiomas: a new surgical technique and results in 5 patients - p. 228 225. Validation of the superior interhemispheric approach for tuberculum sellae meningioma - p. 229
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The Year Book of Neurology and Neurosurgery brings you abstracts of the articles that reported the year's breakthrough developments in neurology and neurosurgery, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed! Readers will find information on a range of topics, including Movement Disorders, Infectious Diseases of the Nervous System, Neoplastic Disease, Pediatric Neurology and Neurosurgery, Cerebrovascular, Neuro-oncology, and Spine. The Year Book of Neurology and Neurosurgery is published annually in June.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Epilepsy and Other Seizure Disorders - p. 8 5. A rapid course through the five electrographic stages of status epilepticus - p. 9 6. Alcohol and drugs in epilepsy: Pathophysiology, presentation, possibilities, and prevention - p. 10 7. Advanced Treatments for Childhood Epilepsy: Beyond Antiseizure Medications - p. 11 8. Dilemmas in the interpretation of diagnostic accuracy studies on presurgical workup for epilepsy surgery - p. 12 9. Diagnosis and management of the epilepsies in children: a summary of the partial update of the 2012 NICE epilepsy guideline - p. 13 10. Epileptic encephalopathies (including severe epilepsy syndromes) - p. 14 11. Antiepileptic Drugs 2012: Recent Advances and Trends - p. 15 12. Benign childhood focal epilepsies - p. 16 13. Antiglutamic Acid Decarboxylase Antibodies in Children With Encephalitis and Status Epilepticus - p. 17 14. Cardiac autonomic dysfunction in drug naïve hot water epilepsy - p. 18 15. Dramatic weight loss with rufinamide - p. 19 16. A randomized controlled trial of flunarizine as add-on therapy and effect on cognitive outcome in children with infantile spasms - p. 20 17. Acute EEG findings in children with febrile status epilepticus: Results of the FEBSTAT study - p. 21 18. Lamotrigine Serum Concentration in Children With Epilepsy - p. 22 19. Feasibility of antiepileptic drug withdrawal following extratemporal resective epilepsy surgery - p. 23 20. Clinical outcomes, quality of life, and costs associated with implantation of vagus nerve stimulation therapy in pediatric patients with drug-resistant epilepsy - p. 24 21. Aggressive behavior and epilepsy: A multicenter study - p. 25 22. Headache - p. 26 23. Thunderclap headache - p. 27 24. Advances in Drug Development for Acute Migraine - p. 28 25. Improvement in Headaches With Continuous Positive Airway Pressure for Obstructive Sleep Apnea: A Retrospective Analysis - p. 29 26. Treatment of Pediatric Migraine in the Emergency Room - p. 30 27. Resident and Fellow Section - p. 31 28. Unusual Headache Syndromes - p. 32 29. Her versus his migraine: multiple sex differences in brain function and structure - p. 33 30. Bilateral acute angle-closure glaucoma in a migraine patient receiving topiramate: a case report - p. 34 31. Obese children suffer more often from migraine - p. 35 32. Frequency and Burden of Headache-Related Nausea: Results From the American Migraine Prevalence and Prevention (AMPP) Study - p. 36 33. The syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis (HaNDL) as an acute ischemic stroke mimic leading to systemic thrombolysis: A case report - p. 37 34. LASH Syndrome: A Third Reported Case Twelve Years After the First - p. 38 35. Does Health Information Exchange Reduce Unnecessary Neuroimaging and Improve Quality of Headache Care in the Emergency Department? - p. 39 36. Dry Eyes and Migraines: Is There Really a Correlation? - p. 40 37. Pediatric Posttraumatic Headache: Two Cases Using Steroids as Abortive Therapy - p. 41 38. Infectious Diseases of the Nervous System - p. 42 39. Ultrasound study shows nerve atrophy in post herpetic neuralgia - p. 43 40. Case 1-2013: A 63-Year-Old Man with Paresthesias and Difficulty Swallowing - p. 44 41. Varicella-zoster virus encephalitis and vasculopathy in a patient treated with fingolimod - p. 45 42. Steroids and Childhood Encephalitis - p. 46 43. Iatrogenic prion diseases in humans: an update - p. 47 44. Seizures and encephalitis: Clinical features, management, and potential pathophysiologic mechanisms - p. 48 45. The Index Case for the Fungal Meningitis Outbreak in the United States - p. 49 46. Nationwide survey of patients in Japan with Bickerstaff brainstem encephalitis: epidemiological and clinical characteristics - p. 50 47. Locally acquired West Nile encephalitis - p. 51 48. Advances in treatment of bacterial meningitis - p. 52 49. Acute meningitis prognosis using cerebrospinal fluid interleukin-6 levels - p. 53 50. Dilemmas in the diagnosis of acute community-acquired bacterial meningitis - p. 54 51. A comparison of tau and 14-3-3 protein in the diagnosis of Creutzfeldt-Jakob disease - p. 55 52. Extreme delta brush: A unique EEG pattern in adults with anti-NMDA receptor encephalitis - p. 56 53. A Life-Threatening Central Nervous System–Tuberculosis Inflammatory Reaction Nonresponsive to Corticosteroids and Successfully Controlled by Infliximab in a Young Patient With a Variant of Juvenile Idiopathic Arthritis - p. 57 54. Movement Disorders - p. 58 55. Clinical features of dopamine agonist withdrawal syndrome in a movement disorders clinic - p. 59 56. Clinical subtypes of anterocollis in parkinsonian syndromes - p. 60 57. Accuracy of a Panel of 5 Cerebrospinal Fluid Biomarkers in the Differential Diagnosis of Patients With Dementia and/or Parkinsonian Disorders - p. 61 58. Cerebral pathological and compensatory mechanisms in the premotor phase of leucine-rich repeat kinase 2 parkinsonism - p. 62 59. Neurologist-associated reduction in PD-related hospitalizations and health care expenditures - p. 63 60. Risk factors for freezing of gait in Parkinson's disease - p. 64 61. Treatment patterns and associated costs with Parkinson's disease levodopa induced dyskinesia - p. 65 62. Anti-cholinergics for axial symptoms in Parkinson's disease after subthalamic stimulation - p. 66 63. Musculoskeletal problems as an initial manifestation of Parkinson's disease: A retrospective study - p. 67 64. Randomized clinical trial of fipamezole for dyskinesia in Parkinson disease (FJORD study) - p. 68 65. Comparison of patient rated treatment response with measured improvement in Parkinson's disease - p. 69 66. A randomized, double-blind, placebo-controlled trial of antidepressants in Parkinson disease - p. 70 67. Randomized trial of deep brain stimulation for Parkinson disease: Thirty-six-month outcomes - p. 71 68. Placebo-controlled trial of lubiprostone for constipation associated with Parkinson disease - p. 72 69. Worsening essential tremor following deep brain stimulation: disease progression versus tolerance - p. 73 70. Multiple Sclerosis and Other Demyelinating Diseases - p. 74 71. “Undiagnosing” multiple sclerosis: the challenge of misdiagnosis in MS - p. 75 72. Fatigue in multiple sclerosis – A brief review - p. 76 73. Low vitamin D and elevated immunoreactivity against Epstein–Barr virus before first clinical manifestation of multiple sclerosis - p. 77 74. Disease-modifying drugs for multiple sclerosis in pregnancy: A systematic review - p. 78 75. Distinct lesion morphology at 7-T MRI differentiates neuromyelitis optica from multiple sclerosis - p. 79 76. Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial - p. 80 77. The cervical spinal cord in neuromyelitis optica patients: A comparative study with multiple sclerosis using diffusion tensor imaging - p. 81 78. Decreased Frontal Lobe Gray Matter Perfusion in Cognitively Impaired Patients with Secondary-Progressive Multiple Sclerosis Detected by the Bookend Technique - p. 82 79. Effect of Aquatic Exercise Training on Fatigue and Health-Related Quality of Life in Patients With Multiple Sclerosis - p. 83 80. Heterogeneity of cortical lesions in multiple sclerosis: Clinical and pathologic implications - p. 84 81. Gray Matter Pathology in MS: A 3-Year Longitudinal Study in a Pediatric Population - p. 85 82. Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis - p. 86 83. Cortical lesion load associates with progression of disability in multiple sclerosis - p. 87 84. Impact of Fingolimod Therapy on Magnetic Resonance Imaging Outcomes in Patients With Multiple Sclerosis - p. 88 85. Ginkgo biloba does not improve cognitive function in MS: A randomized placebo-controlled trial - p. 89 86. Neoplastic Disease - p. 90 87. Refractory temporal lobe epilepsy caused by angiocentric glioma complicated with focal cortical dysplasia: a surgical case series - p. 91 88. An experimental study on acute brain radiation injury: Dynamic changes in proton magnetic resonance spectroscopy and the correlation with histopathology - p. 92 89. Differentiation of glioblastoma and primary CNS lymphomas using susceptibility weighted imaging - p. 93 90. Long-term follow-up of vanishing tumors in the brain: How should a lesion mimicking primary CNS lymphoma be managed? - p. 94 91. Diffusion Tensor Imaging Provides an Insight Into the Microstructure of Meningiomas, High-Grade Gliomas, and Peritumoral Edema - p. 95 92. A randomized trial on the efficacy of methylphenidate and modafinil for improving cognitive functioning and symptoms in patients with a primary brain tumor - p. 96 93. Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation - p. 97 94. Risk of ischemia in glioma surgery: comparison of first and repeat procedures - p. 98 95. Differentiation between Brain Glioblastoma Multiforme and Solitary Metastasis: Qualitative and Quantitative Analysis Based on Routine MR Imaging - p. 99 96. Detection of IDH1 mutation in the plasma of patients with glioma - p. 100 97. Correlation between language function and the left arcuate fasciculus detected by diffusion tensor imaging tractography after brain tumor surgery - p. 101 98. Cognitive functioning early after surgery of gliomas in eloquent areas - p. 102 99. Diagnostic performance of whole brain volume perfusion CT in intra-axial brain tumors: Preoperative classification accuracy and histopathologic correlation - p. 103 100. Diffuse brainstem glioma: prognostic factors - p. 104 101. Cranial Irradiation Increases Risk of Stroke in Pediatric Brain Tumor Survivors - p. 105 102. Comparison of a Strategy Favoring Early Surgical Resection vs a Strategy Favoring Watchful Waiting in Low-Grade Gliomas - p. 106 103. Neuromuscular Disease - p. 107 104. Comprehensive analysis of the TRPV4 gene in a large series of inherited neuropathies and controls - p. 108 105. Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice - p. 109 106. Novel mutation in VCP gene causes atypical amyotrophic lateral sclerosis - p. 110 107. GSK3β mediates muscle pathology in myotonic dystrophy - p. 111 108. Dysfunction of the neuromuscular junction in spinal muscular atrophy types 2 and 3 - p. 112 109. Characterization of a Family With c9FTD/ALS Associated With the GGGGCC Repeat Expansion in C9ORF72 - p. 113 110. Myasthenia gravis in the elderly - p. 114 111. Extensive genetics of ALS: A population-based study in Italy - p. 115 112. Reliability and accuracy of skeletal muscle imaging in limb-girdle muscular dystrophies - p. 116 113. Awaji Criteria for the Diagnosis of Amyotrophic Lateral Sclerosis: A Systematic Review - p. 117 114. Neuro-otology - p. 118 115. Recent advances in central acute vestibular syndrome of a vascular cause - p. 119 116. Gamma Knife Treatment of Growing Vestibular Schwannoma in Norway: A Prospective Study - p. 120 117. Current epidemiology and management trends in acoustic neuroma - p. 121 118. Neuroanatomical correlates of tinnitus revealed by cortical thickness analysis and diffusion tensor imaging - p. 122 119. Endolymphatic Space Imaging in Idiopathic Sudden Sensorineural Hearing Loss With Vertigo - p. 123 120. Short-term audiologic effect of intratympanic gadolinium contrast agent application in patients with Ménière's disease - p. 124 121. Audiovestibular Dysfunction Associated with Adoptive Cell Immunotherapy for Melanoma - p. 125 122. Quality of Life of Patients With Bilateral Vestibulopathy - p. 126 123. Traumatic Tympanic Membrane Perforations: Clinical and Audiometric Findings in 198 Patients - p. 127 124. Benign paroxysmal positional vertigo in people with traumatic spinal cord injury: incidence, treatment efficacy and implications - p. 128 125. A Randomized, Double-Blind, Placebo-Controlled Clinical Study to Assess Safety and Clinical Activity of OTO-104 Given as a Single Intratympanic Injection in Patients With Unilateral Ménière's Disease - p. 129 126. Auditory and Vestibular Symptoms and Chronic Subjective Dizziness in Patients With Ménière's Disease, Vestibular Migraine, and Ménière's Disease With Concomitant Vestibular Migraine - p. 130 127. Irreversible Atorvastatin-Associated Hearing Loss - p. 131 128. Tinnitus in Children: Association With Stress and Trait Anxiety - p. 132 129. Risk of Developing Sudden Sensorineural Hearing Loss in Diabetic Patients: A Population-Based Cohort Study - p. 133 130. Pediatric Neurology - p. 134 131. Early-Onset Epileptic Encephalopathies: Ohtahara Syndrome and Early Myoclonic Encephalopathy - p. 135 132. A Randomized, Double-Blind Study of 30 Versus 20 mg Dexmethylphenidate Extended-Release in Children With Attention-Deficit/Hyperactivity Disorder: Late-Day Symptom Control - p. 136 133. Glucose transporter type I deficiency syndrome: Epilepsy phenotypes and outcomes - p. 137 134. Does a Normalizing Electroencephalogram in Benign Childhood Epilepsy with Centrotemporal Spikes Abort Attention Deficit Hyperactivity Disorder? - p. 138 135. Fever and fever-related epilepsies - p. 139 136. Sleep Disorders - p. 140 137. Society for Ambulatory Anesthesia Consensus Statement on Preoperative Selection of Adult Patients With Obstructive Sleep Apnea Scheduled for Ambulatory Surgery - p. 141 138. Characteristics of refractory vs. medically controlled epilepsy patients with obstructive sleep apnea and their response to CPAP treatment - p. 142 139. The impact of epilepsy on sleep architecture during childhood - p. 143 140. Effect of Continuous Positive Airway Pressure on the Incidence of Hypertension and Cardiovascular Events in Nonsleepy Patients With Obstructive Sleep Apnea: A Randomized Controlled Trial - p. 144 141. Association of Sleep-Disordered Breathing With Cognitive Dysfunction in CKD Stages 4-5 - p. 145 142. Effect of Continuous Positive Airway Pressure Therapy on Cardiovascular Risk Factors in Patients with Type 2 Diabetes and Obstructive Sleep Apnea - p. 146 143. Effect of Continuous Positive Airway Pressure on C-reactive Protein Levels in Sleep Apnea: A Meta-analysis - p. 147 144. Sleep-disordered breathing in multiple sclerosis - p. 148 145. Effects of Continuous Positive Airway Pressure on Neurocognitive Function in Obstructive Sleep Apnea Patients: The Apnea Positive Pressure Long-Term Efficacy Study (APPLES) - p. 149 146. Adaptive Servoventilation for Treatment of Sleep-Disordered Breathing in Heart Failure: A Systematic Review and Meta-Analysis - p. 150 147. Cardiovascular Mortality in Obstructive Sleep Apnea in the Elderly: Role of Long-Term Continuous Positive Airway Pressure Treatment: A Prospective Observational Study - p. 151 148. Utility of overnight pulse oximetry and heart rate variability analysis to screen for sleep-disordered breathing in chronic heart failure - p. 152 149. The Associations of Insomnia With Costly Workplace Accidents and Errors: Results From the America Insomnia Survey - p. 153 150. Association of Insomnia and Short Sleep Duration With Atherosclerosis Risk in the Elderly - p. 154 151. Sleep-disordered Breathing and Cancer Mortality: Results from the Wisconsin Sleep Cohort Study - p. 155 152. Association of multiple sclerosis with restless legs syndrome and other sleep disorders in women - p. 156 153. Miscellaneous - p. 157 154. American Medical Society for Sports Medicine Position Statement: Concussion in Sport - p. 158 155. Advances in stem cell therapy for spinal cord injury - p. 159 156. A pilot study of cerebral and haemodynamic physiological changes during sedation with dexmedetomidine or propofol in patients with acute brain injury - p. 160 157. Complex single gene disorders and epilepsy - p. 161 158. Clinical Applications of Hybrid PET/MRI in Neuroimaging - p. 162 159. Comparative stroke risk of antiepileptic drugs in patients with epilepsy - p. 163 160. Brain Tumors - p. 164 161. Endoscopic endonasal surgery for giant pituitary adenomas: advantages and limitations - p. 165 162. Value of endoscopy for maximizing tumor removal in endonasal transsphenoidal pituitary adenoma surgery - p. 166 163. Hearing preservation in patients with vestibular schwannoma treated with Gamma Knife surgery - p. 167 164. Longitudinal analysis of hearing before and after radiosurgery for vestibular schwannoma - p. 168 165. Long-term hearing outcomes following stereotactic radiosurgery for vestibular schwannoma: patterns of hearing loss and variables influencing audiometric decline - p. 169 166. Long-term safety and efficacy of stereotactic radiosurgery for vestibular schwannomas: evaluation of 440 patients more than 10 years after treatment with Gamma Knife surgery - p. 170 167. Gamma Knife surgery in the treatment paradigm for foramen magnum meningiomas - p. 171 168. Giant anterior clinoidal meningiomas: surgical technique and outcomes - p. 172 169. The role of radiotherapy following gross-total resection of atypical meningiomas - p. 173 170. Cerebral revascularization and carotid artery resection at the skull base for treatment of advanced head and neck malignancies - p. 174 171. Chromosomal alterations, prognostic factors, and targeted molecular therapies for malignant meningiomas - p. 175 172. Ten years of experience with microsurgical treatment of large and giant petroclival meningiomas - p. 176 173. Radiation-induced meningiomas after high-dose cranial irradiation - p. 177 174. The role of radiotherapy following gross-total resection of atypical meningiomas - p. 178 175. Single-Fraction Radiosurgery of Benign Intracranial Meningiomas - p. 179 176. The influence of surgery on quality of life in patients with intracranial meningiomas: a prospective study - p. 180 177. Risk for leptomeningeal seeding after resection for brain metastases: Implication of tumor location with mode of resection - p. 181 178. Systematic review of primary intracranial glioblastoma multiforme with symptomatic spinal metastases, with two illustrative patients - p. 182 179. Retrosigmoid Approach to Cerebellopontine Angle Tumor Resection: Surgical Modifications - p. 183 180. Early rehabilitation after surgery improves functional outcome in inpatients with brain tumours - p. 184 181. Chromosomal anomalies and prognostic markers for intracranial and spinal ependymomas - p. 185 182. Imaging modalities in high-grade gliomas: Pseudoprogression, recurrence, or necrosis? - p. 186 183. Frameless robotically targeted stereotactic brain biopsy: feasibility, diagnostic yield, and safety - p. 187 184. Cerebrovascular - p. 188 185. Long-term Results of Gamma Knife Surgery for Partially Embolized Arteriovenous Malformations - p. 189 186. Validation and absolute quantification of MR perfusion compared with CT perfusion in patients with unilateral cerebral arterial stenosis - p. 190 187. Safety and Efficacy of Intraoperative Angiography in Craniotomies for Cerebral Aneurysms and Arteriovenous Malformations: A Review of 1093 Consecutive Cases - p. 191 188. Solitaire flow restoration device versus the Merci Retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial - p. 192 189. Early Postmarket Results After Treatment of Intracranial Aneurysms With the Pipeline Embolization Device: A US Multicenter Experience - p. 193 190. A Comparison of Radiation Exposure between Diagnostic CTA and DSA Examinations of Cerebral and Cervicocerebral Vessels - p. 194 191. Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke - p. 195 192. Does Stent Implantation Improve the Result of Repeat Embolization in Recanalized Aneurysms? - p. 196 193. Distinctive flow pattern of wall shear stress and oscillatory shear index: similarity and dissimilarity in ruptured and unruptured cerebral aneurysm blebs - p. 197 194. Subarachnoid Hemorrhage Incidence in the United States Does Not Vary with Season or Temperature - p. 198 195. Surgical results of the Carotid Occlusion Surgery Study - p. 199 196. Stroke After Carotid Stenting and Endarterectomy in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST) - p. 200 197. Pediatric Neurosurgery - p. 201 198. Craniocervical fusions in children - p. 202 199. Image-guided cerebrospinal fluid shunting in children: catheter accuracy and shunt survival - p. 203 200. Optimal timing of autologous cranioplasty after decompressive craniectomy in children - p. 204 201. Treatment of choroid plexus tumors: a 20-year single institutional experience - p. 205 202. Internal cranial expansion surgery for the treatment of refractory idiopathic intracranial hypertension - p. 206 203. Follow-up imaging to detect recurrence of surgically treated pediatric arteriovenous malformations - p. 207 204. Programmable shunt valve affected by exposure to a tablet computer - p. 208 205. Nonprogrammable and programmable cerebrospinal fluid shunt valves: a 5-year study - p. 209 206. The use of abdominal binders to treat over-shunting headaches - p. 210 207. Choroid plexus coagulation for hydrocephalus not due to CSF overproduction: a review - p. 211 208. Shunt survival after failed endoscopic treatment of hydrocephalus - p. 212 209. Second impact syndrome in football: new imaging and insights into a rare and devastating condition - p. 213 210. Spine - p. 214 211. Interrater and Intrarater Reliability of the Kuntz et al New Deformity Classification System - p. 215 212. Cervical decompression and reconstruction without intraoperative neurophysiological monitoring - p. 216 213. Surgical management of unknown primary tumors metastatic to the spine - p. 217 214. Results and complications after 2-level axial lumbar interbody fusion with a minimum 2-year follow-up - p. 218 215. Unilateral surgical approach for lumbar disc herniation with contralateral symptoms - p. 219 216. Outcomes of instrumented fusion in the pediatric cervical spine - p. 220 217. 2012 Young Investigator Award Winner: The Distribution of Body Mass as a Significant Risk Factor for Lumbar Spinal Fusion Postoperative Infections - p. 221 218. An Injectable Nucleus Pulposus Implant Restores Compressive Range of Motion in the Ovine Disc - p. 222 219. Incidental durotomy after spinal surgery: a prospective study in an academic institution: Presented at the 2012 Joint Spine Section Meeting - p. 223 220. Perioperative and delayed complications associated with the surgical treatment of cervical spondylotic myelopathy based on 302 patients from the AOSpine North America Cervical Spondylotic Myelopathy Study: Presented at the 2011 Spine Section Meeting - p. 224 221. Microscope Sterility During Spine Surgery - p. 225 222. C2 Nerve Root Sectioning in Posterior C1-2 Instrumented Fusions - p. 226 223. Surgical Techniques - p. 227 224. Intradural anterior petrosectomy for petroclival meningiomas: a new surgical technique and results in 5 patients - p. 228 225. Validation of the superior interhemispheric approach for tuberculum sellae meningioma - p. 229
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