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The Year Book of Pulmonary Disease brings you abstracts of the articles that reported the year's breakthrough developments in pulmonary disease carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. Topics such as Asthma and Cystic Fibrosis, Chronic Obstructive Pulmonary Disease, Lung Cancer, Community-Acquired Pneumonia, Lung Transplantation, Sleep Disorders, and Critical Care Medicine are represented highlighting the most current and relevant articles in the field.

1. Invasive Pneumococcal Disease Following the Introduction of 13-Valent Conjugate Vaccine in Children in New York City From 2007 to 2012 - p. 123 2. Effectiveness of 23-Valent Pneumococcal Polysaccharide Vaccine Against Invasive Disease and Hospital-Treated Pneumonia Among People Aged ≥65 Years: A Retrospective Case-Control Study - p. 124 3. Sensitivity, Specificity, and Positivity Predictors of the Pneumococcal Urinary Antigen Test in Community-Acquired Pneumonia - p. 125 4. Pneumonia Pathogen Characterization Is an Independent Determinant of Hospital Readmission - p. 126 5. Association Between Hospitalization With Community-Acquired Laboratory-Confirmed Influenza Pneumonia and Prior Receipt of Influenza Vaccination - p. 127 6. The Effect of Macrolide Resistance on the Presentation and Outcome of Patients Hospitalized for Streptococcus pneumoniae Pneumonia - p. 128 7. Assessment of Risks of Pulmonary Infection During 12 Months Following Immunosuppressive Treatment for Active Connective Tissue Diseases: A Large-scale Prospective Cohort Study - p. 129 8. Risk of Pneumonia in New Users of Cholinesterase Inhibitors for Dementia - p. 130 9. First Human Challenge Testing of a Pneumococcal Vaccine: Double-Blind Randomized Controlled Trial - p. 131 10. 6. Lung Transplantation - p. 132 11. Lung Transplantation With Lungs From Older Donors: Recipient and Surgical Factors Affect Outcomes - p. 133 12. Functional outcomes and quality of life after normothermic ex vivo lung perfusion lung transplantation - p. 134 13. Association Between Prolonged Graft Ischemia and Primary Graft Failure or Survival Following Lung Transplantation - p. 135 14. Lung transplantation from donation after cardiocirculatory death: a systematic review and meta-analysis - p. 136 15. Is There an Age Limit to Lung Transplantation? - p. 137 16. Body Composition and Mortality after Adult Lung Transplantation in the United States - p. 138 17. Determining eligibility for lung transplantation: A nationwide assessment of the cutoff glomerular filtration rate - p. 139 18. Influence of age on survival in adult patients on extracorporeal membrane oxygenation before lung transplantation - p. 140 19. Clinical and demographic factors associated with post–lung transplantation survival in individuals with cystic fibrosis - p. 141 20. Clinical outcomes of lung transplant recipients with telomerase mutations - p. 142 21. The Natural History of Lung Function after Lung Transplantation for α1-Antitrypsin Deficiency - p. 143 22. Longitudinal Forced Vital Capacity Monitoring as a Prognostic Adjunct after Lung Transplantation - p. 144 23. Continued Utility of Single-Lung Transplantation in Select Populations: Chronic Obstructive Pulmonary Disease - p. 145 24. 7. Sleep Disorders - p. 146 25. 7.1 Central Sleep Apnea And Heart Failure - p. 147 26. Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure - p. 148 27. 7.2 Sleep-Disordered Breathing Outcomes - p. 149 28. Association of incident obstructive sleep apnoea with outcomes in a large cohort of US veterans - p. 150 29. Obstructive sleep apnoea in the elderly: role of continuous positive airway pressure treatment - p. 151 30. Perioperative Assessment and Management for Sleep Apnea in the Ambulatory Surgical Patient - p. 152 31. 7.3 Cpap Treatment And Benefits - p. 153 32. Obstructive Sleep Apnea Is Associated with Nonalcoholic Steatohepatitis and Advanced Liver Histology - p. 154 33. A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial - p. 155 34. 7.4 Non-Cpap Treatment of Sleep-Disordered Breathing - p. 156 35. Surgical Management of OSA in Adults - p. 157 36. 7.5 Pediatric Sleep-Disordered Breathing - p. 158 37. Sleep Disordered Breathing and Academic Performance: A Meta-analysis - p. 159 38. 7.6 Epidemiology of Sleep-Disordered Breathing - p. 160 39. Racial/Ethnic Differences in Sleep Disturbances: The Multi-Ethnic Study of Atherosclerosis (MESA) - p. 161 40. 7.7 Non-Pulmonary Sleep - p. 162 41. Cognitive Behavioral Therapy for Chronic Insomnia: A Systematic Review and Meta-analysis - p. 163 42. 8. Critical Care Medicine - p. 164 43. 8.1 Acute Respiratory Disorder Syndrome - p. 165 44. Determination of Lung Volume and Hemodynamic Changes During High-Frequency Ventilation Recruitment in Preterm Neonates with Respiratory Distress Syndrome - p. 166 45. Soluble Receptor for Advanced Glycation End-Products Predicts Impaired Alveolar Fluid Clearance in Acute Respiratory Distress Syndrome - p. 167 46. Influenza-Induced Priming and Leak of Human Lung Microvascular Endothelium upon Exposure to Staphylococcus aureus - p. 168 47. Acute respiratory distress syndrome in patients with and without diffuse alveolar damage: an autopsy study - p. 169 48. Estimating Dead-Space Fraction for Secondary Analyses of Acute Respiratory Distress Syndrome Clinical Trials - p. 170 49. 8.2 Acute Respiratory Failure - p. 171 50. CPAP and High-Flow Nasal Cannula Oxygen in Bronchiolitis - p. 172 51. Positive end-expiratory pressure titration at bedside using electrical impedance tomography in post-operative cardiac surgery patients - p. 173 52. Driving Pressure and Survival in the Acute Respiratory Distress Syndrome - p. 174 53. Extravascular Lung Water and Pulmonary Vascular Permeability Index as Markers Predictive of Postoperative Acute Respiratory Distress Syndrome: A Prospective Cohort Investigation - p. 175 54. Veno-venous extracorporeal CO2 removal improves pulmonary hemodynamics in a porcine ARDS model - p. 176 55. Effect of Noninvasive Ventilation vs Oxygen Therapy on Mortality Among Immunocompromised Patients With Acute Respiratory Failure: A Randomized Clinical Trial - p. 177 56. 8.3 Cardiopulmonary Interactions - p. 178 57. Hemodynamic instability in patients undergoing pulmonary embolectomy: institutional experience - p. 179 58. Extracorporeal cardiopulmonary resuscitation in bedside echocardiography–diagnosed massive pulmonary embolism - p. 180 59. Successful use of ECMO as a bridge to surgical embolectomy in Life-Threatening Pulmonary Embolism - p. 181 60. First description of successful weaning from ECMO in a patient with Eisenmenger syndrome after repair of pulmonary artery dissection - p. 182 61. Hemodynamic Deterioration During Extracorporeal Membrane Oxygenation Weaning in a Patient With a Total Artificial Heart - p. 183 62. 8.4 Miscellaneous - p. 184 63. Safety and efficacy of ultrasound-accelerated catheter-directed lytic therapy in acute pulmonary embolism with and without hemodynamic instability - p. 185 64. A new device for the prevention of pulmonary embolism in critically ill patients: Results of the European Angel Catheter Registry - p. 186 65. Failure of Anticoagulant Thromboprophylaxis: Risk Factors in Medical-Surgical Critically Ill Patients - p. 187 66. Pulmonary embolism in the setting of HELLP syndrome - p. 188 67. Respiratory Syncytial Virus Genomic Load and Disease Severity Among Children Hospitalized With Bronchiolitis: Multicenter Cohort Studies in the United States and Finland - p. 189 68. TRPV4 Is Required for Hypoxic Pulmonary Vasoconstriction - p. 190 69. 8.5 Pulmonary Hypertension In the ICU - p. 191 70. Mechanical Support for the Failing Right Ventricle in Patients With Precapillary Pulmonary Hypertension - p. 192 71. Scleroderma and pulmonary hypertension complicating two pregnancies: use of neuraxial anesthesia, general anesthesia, epoprostenol and a multidisciplinary approach for cesarean delivery - p. 193 72. 8.6 Imaging and monitoring in the ICU - p. 194 73. Acute Lung Injury After Bilateral Lung Transplantation Due to Contralateral Pulmonary Arterial Anastomotic Obstruction - p. 195

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The Year Book of Pulmonary Disease brings you abstracts of the articles that reported the year's breakthrough developments in pulmonary disease carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. Topics such as Asthma and Cystic Fibrosis, Chronic Obstructive Pulmonary Disease, Lung Cancer, Community-Acquired Pneumonia, Lung Transplantation, Sleep Disorders, and Critical Care Medicine are represented highlighting the most current and relevant articles in the field.

1. Invasive Pneumococcal Disease Following the Introduction of 13-Valent Conjugate Vaccine in Children in New York City From 2007 to 2012 - p. 123 2. Effectiveness of 23-Valent Pneumococcal Polysaccharide Vaccine Against Invasive Disease and Hospital-Treated Pneumonia Among People Aged ≥65 Years: A Retrospective Case-Control Study - p. 124 3. Sensitivity, Specificity, and Positivity Predictors of the Pneumococcal Urinary Antigen Test in Community-Acquired Pneumonia - p. 125 4. Pneumonia Pathogen Characterization Is an Independent Determinant of Hospital Readmission - p. 126 5. Association Between Hospitalization With Community-Acquired Laboratory-Confirmed Influenza Pneumonia and Prior Receipt of Influenza Vaccination - p. 127 6. The Effect of Macrolide Resistance on the Presentation and Outcome of Patients Hospitalized for Streptococcus pneumoniae Pneumonia - p. 128 7. Assessment of Risks of Pulmonary Infection During 12 Months Following Immunosuppressive Treatment for Active Connective Tissue Diseases: A Large-scale Prospective Cohort Study - p. 129 8. Risk of Pneumonia in New Users of Cholinesterase Inhibitors for Dementia - p. 130 9. First Human Challenge Testing of a Pneumococcal Vaccine: Double-Blind Randomized Controlled Trial - p. 131 10. 6. Lung Transplantation - p. 132 11. Lung Transplantation With Lungs From Older Donors: Recipient and Surgical Factors Affect Outcomes - p. 133 12. Functional outcomes and quality of life after normothermic ex vivo lung perfusion lung transplantation - p. 134 13. Association Between Prolonged Graft Ischemia and Primary Graft Failure or Survival Following Lung Transplantation - p. 135 14. Lung transplantation from donation after cardiocirculatory death: a systematic review and meta-analysis - p. 136 15. Is There an Age Limit to Lung Transplantation? - p. 137 16. Body Composition and Mortality after Adult Lung Transplantation in the United States - p. 138 17. Determining eligibility for lung transplantation: A nationwide assessment of the cutoff glomerular filtration rate - p. 139 18. Influence of age on survival in adult patients on extracorporeal membrane oxygenation before lung transplantation - p. 140 19. Clinical and demographic factors associated with post–lung transplantation survival in individuals with cystic fibrosis - p. 141 20. Clinical outcomes of lung transplant recipients with telomerase mutations - p. 142 21. The Natural History of Lung Function after Lung Transplantation for α1-Antitrypsin Deficiency - p. 143 22. Longitudinal Forced Vital Capacity Monitoring as a Prognostic Adjunct after Lung Transplantation - p. 144 23. Continued Utility of Single-Lung Transplantation in Select Populations: Chronic Obstructive Pulmonary Disease - p. 145 24. 7. Sleep Disorders - p. 146 25. 7.1 Central Sleep Apnea And Heart Failure - p. 147 26. Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure - p. 148 27. 7.2 Sleep-Disordered Breathing Outcomes - p. 149 28. Association of incident obstructive sleep apnoea with outcomes in a large cohort of US veterans - p. 150 29. Obstructive sleep apnoea in the elderly: role of continuous positive airway pressure treatment - p. 151 30. Perioperative Assessment and Management for Sleep Apnea in the Ambulatory Surgical Patient - p. 152 31. 7.3 Cpap Treatment And Benefits - p. 153 32. Obstructive Sleep Apnea Is Associated with Nonalcoholic Steatohepatitis and Advanced Liver Histology - p. 154 33. A Bayesian cost-effectiveness analysis of a telemedicine-based strategy for the management of sleep apnoea: a multicentre randomised controlled trial - p. 155 34. 7.4 Non-Cpap Treatment of Sleep-Disordered Breathing - p. 156 35. Surgical Management of OSA in Adults - p. 157 36. 7.5 Pediatric Sleep-Disordered Breathing - p. 158 37. Sleep Disordered Breathing and Academic Performance: A Meta-analysis - p. 159 38. 7.6 Epidemiology of Sleep-Disordered Breathing - p. 160 39. Racial/Ethnic Differences in Sleep Disturbances: The Multi-Ethnic Study of Atherosclerosis (MESA) - p. 161 40. 7.7 Non-Pulmonary Sleep - p. 162 41. Cognitive Behavioral Therapy for Chronic Insomnia: A Systematic Review and Meta-analysis - p. 163 42. 8. Critical Care Medicine - p. 164 43. 8.1 Acute Respiratory Disorder Syndrome - p. 165 44. Determination of Lung Volume and Hemodynamic Changes During High-Frequency Ventilation Recruitment in Preterm Neonates with Respiratory Distress Syndrome - p. 166 45. Soluble Receptor for Advanced Glycation End-Products Predicts Impaired Alveolar Fluid Clearance in Acute Respiratory Distress Syndrome - p. 167 46. Influenza-Induced Priming and Leak of Human Lung Microvascular Endothelium upon Exposure to Staphylococcus aureus - p. 168 47. Acute respiratory distress syndrome in patients with and without diffuse alveolar damage: an autopsy study - p. 169 48. Estimating Dead-Space Fraction for Secondary Analyses of Acute Respiratory Distress Syndrome Clinical Trials - p. 170 49. 8.2 Acute Respiratory Failure - p. 171 50. CPAP and High-Flow Nasal Cannula Oxygen in Bronchiolitis - p. 172 51. Positive end-expiratory pressure titration at bedside using electrical impedance tomography in post-operative cardiac surgery patients - p. 173 52. Driving Pressure and Survival in the Acute Respiratory Distress Syndrome - p. 174 53. Extravascular Lung Water and Pulmonary Vascular Permeability Index as Markers Predictive of Postoperative Acute Respiratory Distress Syndrome: A Prospective Cohort Investigation - p. 175 54. Veno-venous extracorporeal CO2 removal improves pulmonary hemodynamics in a porcine ARDS model - p. 176 55. Effect of Noninvasive Ventilation vs Oxygen Therapy on Mortality Among Immunocompromised Patients With Acute Respiratory Failure: A Randomized Clinical Trial - p. 177 56. 8.3 Cardiopulmonary Interactions - p. 178 57. Hemodynamic instability in patients undergoing pulmonary embolectomy: institutional experience - p. 179 58. Extracorporeal cardiopulmonary resuscitation in bedside echocardiography–diagnosed massive pulmonary embolism - p. 180 59. Successful use of ECMO as a bridge to surgical embolectomy in Life-Threatening Pulmonary Embolism - p. 181 60. First description of successful weaning from ECMO in a patient with Eisenmenger syndrome after repair of pulmonary artery dissection - p. 182 61. Hemodynamic Deterioration During Extracorporeal Membrane Oxygenation Weaning in a Patient With a Total Artificial Heart - p. 183 62. 8.4 Miscellaneous - p. 184 63. Safety and efficacy of ultrasound-accelerated catheter-directed lytic therapy in acute pulmonary embolism with and without hemodynamic instability - p. 185 64. A new device for the prevention of pulmonary embolism in critically ill patients: Results of the European Angel Catheter Registry - p. 186 65. Failure of Anticoagulant Thromboprophylaxis: Risk Factors in Medical-Surgical Critically Ill Patients - p. 187 66. Pulmonary embolism in the setting of HELLP syndrome - p. 188 67. Respiratory Syncytial Virus Genomic Load and Disease Severity Among Children Hospitalized With Bronchiolitis: Multicenter Cohort Studies in the United States and Finland - p. 189 68. TRPV4 Is Required for Hypoxic Pulmonary Vasoconstriction - p. 190 69. 8.5 Pulmonary Hypertension In the ICU - p. 191 70. Mechanical Support for the Failing Right Ventricle in Patients With Precapillary Pulmonary Hypertension - p. 192 71. Scleroderma and pulmonary hypertension complicating two pregnancies: use of neuraxial anesthesia, general anesthesia, epoprostenol and a multidisciplinary approach for cesarean delivery - p. 193 72. 8.6 Imaging and monitoring in the ICU - p. 194 73. Acute Lung Injury After Bilateral Lung Transplantation Due to Contralateral Pulmonary Arterial Anastomotic Obstruction - p. 195

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