The 29th European Symposium on Computer Aided Process Engineering, contains the papers presented at the 29th European Symposium of Computer Aided Process Engineering (ESCAPE) event held in Eindhoven, The Netherlands, from June 16-19, 2019. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students, and consultants for chemical industries.
1. Cover image - p. xxiii 2. Title page - p. xxiii 3. Table of Contents - p. xxiii 4. Copyright - p. xxiii 5. Preface - p. xxiii 6. Organizing & Scientific committees - p. xxv 7. Plenary and Keynotes Lectures - p. xxvii 8. Economic Nonlinear Model Predictive Control of Multi-Product Air Separation Processes - p. 1 9. From Single Process Simulation and Optimization to Decision Making Based on a Multitude of Solutions - p. 7 10. A Framework for the Integration of Holistic Sustainability Assessment in Computer-Aided Molecular Design - p. 13 11. Iterative Medium-Term Production Scheduling of an Industrial Formulation Plant - p. 19 12. Towards Model-Based Optimization for Quality by Design in Biotherapeutics Production - p. 25 13. Review of override control methods - p. 31 14. A comparison of the performance of multi-objective optimization methodologies for solvent design - p. 37 15. Automated open-loop control of directed self-assembly with multiple electrokinetic actuators in microfluidic devices - p. 43 16. Automatic synthesis of distillation processes for the separation of azeotropic multi-component systems - p. 49 17. Design and Planning of Agri-Food Supply Chains - p. 55 18. An Explicit Online Resource-Task Network Scheduling Formulation to Avoid Scheduling Nervousness - p. 61 19. Optimizing Return on Investment in Biomass Conversion Networks under Uncertainty Using Data-Driven Adaptive Robust Optimization - p. 67 20. Towards a systematic framework for the synthesis of operable process intensification systems - application to reactive distillation systems - p. 73 21. Optimisation and control of a distributed energy resource network using Internet-of-Things technologies - p. 79 22. Engineering success: What does it take to get PSE technologies used? - p. 85 23. Component based development of computer-aided tools for different applications - p. 91 24. Predictive LCA - a systems approach to integrate LCA decisions ahead of design - p. 97 25. Energy System Modelling in support of the Energy Transition - p. 103 26. Process Systems Engineering from an industrial and academic perspective - p. 109 27. Process design meets sustainability: overview on the use of modelling tools for process design and sustainability assessment at Corbion - p. 115 28. New MINLP Formulations for Flexibility Analysis for Measured and Unmeasured Uncertain Parameters - p. 121 29. Mathematical process modelling past, present and future – a personal perspective - p. 127 30. Process-product synthesis, design and integration - p. 132 31. Simultaneous design and controllability optimization for the reaction zone for furfural bioproduction - p. 133 32. Design and Optimization of Azeotropic and Extractive Distillation to Purify Furfural Considering Safety, Environmental and Economic Issues. - p. 139 33. Revisiting Classic Acetic Acid Synthesis: Optimal Hydrogen Consumption and Carbon Dioxide Utilization - p. 145 34. Innovative application of statistical analysis for the optimization of CO2 absorption from flue gas with ionic liquid - p. 151 35. Synthesis, Design and Optimization of Schemes to Produce 2, 3-Butanediol Considering Economic, Environmental and Safety issues - p. 157 36. ORC on tour: Integrated design of dynamic ORC processes and working fluids for waste-heat recovery from heavy-duty vehicles - p. 163 37. Optimisation of multi effect distillation based desalination system for minimum production cost for freshwater - p. 169 38. A model-based approach for optimizing petroleum refinery configuration for heavy oil processing - p. 175 39. Performance Evaluation of Reverse Osmosis Brackish Water Desalination Plant with Different Recycled Ratios of Retentate - p. 181 40. Globally Optimal Design of Double Pipe Heat Exchangers using Local Properties and Discretized Models - p. 187 41. Optimization of Biogas to Syngas via Combined Super-Dry and Tri-Reforming. Analysis of Fischer-Tropsch Fuels Production - p. 193 42. Optimising European supply chains for carbon capture, transport and sequestration, including uncertainty on geological storage availability - p. 199 43. Applying a Sustainability Metric in Energy, Water and Food Nexus Applications; A Biomass Utilization Case Study to Improve Investment Decisions - p. 205 44. Technoeconomic MINLP Optimisation of Liquid-Liquid Extraction (LLE) Cascades for Continuous Pharmaceutical Manufacturing (CPM) of Atropine - p. 211 45. Multi-product reactive distillation process for higher acrylates production - p. 217 46. A point estimate method-based back-off approach to robust optimization: application to pharmaceutical processes - p. 223 47. Design and Operation Optimization for Water and Power Cogeneration System by Reverse Osmosis and Renewable Energy Technologies - p. 229 48. Modelling of extractive heterogeneous-azeotropic distillation in dividing wall column - p. 235 49. Optimization of an Integrated First- and Second-Generation Ethanol Production Plant with Focus on Hydrolysis Parameters - p. 241 50. Optimization of seaweed-based biorefinery with zero carbon emissions potential - p. 247 51. Optimal design for integrated macroalgae-based biorefinery via mixed alcohol synthesis - p. 253 52. Global Optimization of Counter Current Gasketed Plate Heat Exchanger - p. 259 53. An optimization model for a biorefinery system based on process design and logistics - p. 265 54. Design of smart liquid-liquid extraction columns for downstream separations of biopharmaceuticals using deep Q-learning algorithm - p. 271 55. Process design and techno-economic analysis of a pineapple wine production plant under the context of the Choco-Colombia region - p. 277 56. Optimisation of Aqueous Two-Phase Systems - p. 283 57. Development of a biorefinery scheme to produce biofuels from waste cooking oil - p. 289 58. A network model-based optimisation analysis for the utilisation of CO2 in Qatar’s chemical industries - p. 295 59. Superstructure Optimization for the Production of Fuels, Fertilizers and Power using Biomass Gasification - p. 301 60. Techno-Economic-Environmental Study for Recovery of Novel Water Source within a Power Plant - Desalination Complex - p. 307 61. Molecular tracking: A novel approach for multicomponent distillation column design - p. 313 62. Development of a Model-Based Quality-by-Control Framework for Crystallization Design - p. 319 63. Towards development of a decision support tool for conceptual design of wastewater treatment plants using stochastic simulation optimization - p. 325 64. Targeting of sustainable chemical processes using data envelopment analysis: application to liquid fuels for transportation - p. 331 65. Production scheduling of semi-continuous milk processing facility - p. 337 66. Fast Bypass Selection Method during the Heat Exchanger Network Synthesis - p. 343 67. Integrating Oil Refineries and Bio-refineries: Upgrading Acetone, Butanol and Ethanol to High-Value Products - p. 349 68. Heat-Integrated Reactive distillation processes to produce Ethyl Levulinate: Design and Optimization including Environmental, Safety and Economics Aspects - p. 355 69. Risk-conscious approach to optimizing bioenergy investments in the Brazilian sugarcane industry - p. 361 70. Production of chemicals from syngas: an enviro-economic model-based investigation - p. 367 71. A new index for chemical process design considering risk analysis and controllability - p. 373 72. An MILP model for safe multi-floor process plant layout - p. 379 73. A Generalized, Nonsmooth Operator for Process Integration - p. 385 74. Analysis of Process Alternatives for Energy-Efficient Bioethanol Downstream Processing - p. 391 75. A Model based analysis in applying Anderson–Schulz–Flory (ASF) equation with CO2 Utilisation on the Fischer Tropsch Gas-to-liquid Process - p. 397 76. Scalable manufacturing of nanostructured materials by atomic layer deposition in fluidized bed reactors - p. 403 77. Effect of Non-Ideal Kinetics on Hybrid Reactive Distillation Models for Selectivity Engineering - p. 409 78. Integrated Design of Solvents and Processes based on Reaction Kinetics from Quantum Chemical Prediction Methods - p. 415 79. Novel refrigeration cycle configurations for performance improvements in LNG processes at small scale - p. 421 80. Involving the Water-Energy-Food Nexus in Integrating Low-Income and Isolated Communities - p. 427 81. Integration of Consumer Preferences and Heuristic Knowledge in the Design of Formulated Products: Application to a Cosmetic Emulsion - p. 433 82. Economic Study of the Urea Alcoholysis Process for Dimethyl Carbonate Production - p. 439 83. Effect of Ambient Conditions on Boil Off Gas Generation in LNG regasification terminals - p. 445 84. An MPCC Reactive Distillation Optimization Model for Multi-Objective Fischer–Tropsch Synthesis - p. 451 85. Techno-economic analysis of alternative reactive purification technologies in the lactic acid production process. - p. 457 86. Optimal design of post combustion CO2 capture processes based on phase-change solvents - p. 463 87. Optimization of a hydroformulation process in a thermomorphic solvent system using a commercial steady-state process simulator and a memetic algorithm - p. 469 88. Exergy analysis for energy integration in a bioethanol production process to determine heat exchanger networks feasibility - p. 475 89. ProCAFD: Computer-aided Tool for Sustainable Process Synthesis, Intensification and Hybrid solutions - p. 481 90. A multi-objective multi-period optimization of carbon integration networks in industrial parks - p. 487 91. Improved problem constraints modeling based using classification - p. 493 92. Bioethanol Production with Cyanobacteria by a Two-Stage Fermentation Strategy - p. 499 93. Application of plate heat exchangers into heat exchanger networks retrofit with fixed structure - p. 505 94. Clustering alternative product formulations using graphs - p. 511 95. Analysis of the Tri-Reforming of Methane in a Membrane Reactor - p. 517 96. Design of a novel sour water stripping unit - p. 523 97. Techno-economic Assessment of Future Generation IGCC Processes with Control on Greenhouse Gas Emissions - p. 529 98. Synthesis of Solar Heat Network for Preheating of Industrial Process Streams - p. 535 99. Methods, models and computational tools for PSE - p. 540 100. On the implementation of generalized polynomial chaos in dynamic optimization under stochastic uncertainty: a user perspective - p. 541 101. Optimal dose administration of renally excreted drugs - p. 547 102. Automating HAZOP studies using D-higraphs - p. 553 103. A Novel Optimizable Inherent Safety Index Based on Fuzzy Logic - p. 559 104. Optimization under uncertainty of melatonin dosing for critically ill patients - p. 565 105. Optimization of a shell-and-tube heat exchanger using the grey wolf algorithm - p. 571 106. Optimization Under Uncertainty Based on a Data-driven Model for a Chloralkali Electrolyzer Cell - p. 577 107. Parameter Estimation for Thermodynamic Models Using an Identifiability Analysis and Subset Selection - p. 583 108. Evaluation of Discretization Methods for Modeling the Chloralkali Membrane Process - p. 589 109. A steady-state and dynamic simulation tool for solid oxide fuel cell operation applications - p. 595 110. Thermal conductivity prediction of molten salt-based nanofluids for energy storage applications - p. 601 111. Nanoparticle behaviour in multiphase turbulent channel flow - p. 607 112. Multi-objective optimisation of chemical processes via improved genetic algorithms: A novel trade-off and termination criterion - p. 613 113. DyOS - A Framework for Optimization of Large-Scale Differential Algebraic Equation Systems - p. 619 114. Rate-based modelling and simulation of pilot scale distillation column - p. 625 115. Computer-Assisted Experiments for the Identification of the Two-Phase Viscosity of Fluids - p. 631 116. Increasing the Reliability of Parameter Estimates by Iterative Model-based Design of Experiments Using a Flowsheet-Simulator - p. 637 117. Estimating mixture properties from batch distillation using semi-rigorous and rigorous models - p. 643 118. An MILP Approach for Short-term Scheduling of Batch Operations - p. 649 119. Synthesis and optimization of refinery hydrogen network using surrogate models - p. 655 120. Real-time design space description in pharmaceutical manufacturing - p. 661 121. Flexibility Assessment of a Distillation Train: Nominal vs Perturbated Conditions Optimal Design - p. 667 122. Dynamic Modelling and Simulation of Chinese Hamster Ovary (CHO) Cell Fermentation for Advanced Biopharmaceutical Manufacturing - p. 673 123. Statistical diagnosis of process-model mismatch by means of the Lagrange multiplier test - p. 679 124. Optimal design of experiments for the identification of kinetic models of 5-hydroxymethylfurfural hydrogenation - p. 685 125. On the Solution of the Smoluchowski Coagulation Equation Using a Conservative Discretization Approach (CDA) - p. 691 126. Coordination of multiple production and utility systems in a multi-leader multi-follower Stackelberg game - p. 697 127. From peak power prices to seasonal storage: Long-term operational optimization of energy systems by time-series decomposition - p. 703 128. Scale-up Modeling of a Pharmaceutical Antisolvent Crystallization via a Hybrid Method of Computational Fluid Dynamics and Compartmental Modeling - p. 709 129. Modelling of bubble column hydrodynamics using CFD and SQMOM as a population balance solver - p. 715 130. Single-shooting optimization of an industrial process through co-simulation of a modularized Aspen Plus Dynamics model - p. 721 131. A Discrete-time MILP Formulation for the Optimal Scheduling of Maintenance Tasks on Oil and Gas Wells and Surface Facilities - p. 727 132. Optimal design of multi-stage depressurization systems using dynamic modelling - p. 733 133. Innovative mapping method for screening reactive distillation designs - p. 739 134. Integrated Process and Controller Design Software Tool – ProCACD - p. 745 135. Computational Fluid Dynamics of Rectangular Monolith Reactor vs. Packed-Bed Column for Sorption-Enhanced Water-Gas Shift - p. 751 136. A novel process monitoring approach based on Feature Points Distance Dynamic Autoencoder - p. 757 137. A Framework for Multi-level Life Cycle Analysis of the Energy System - p. 763 138. Nonlinear dynamic analysis of chemical engineering processes described by differential-algebraic equations systems - p. 769 139. Parameter Estimation for Thermal Runaway of Li-ion cells: a Gaussian Process approach - p. 775 140. Improved Design of Experiments for Identification of MIMO Systems - p. 781 141. Machine Learning of Molecular Classification and Quantum Mechanical Calculations - p. 787 142. Comparative CFD analysis of thermal energy storage materials in photovoltaic/thermal panels - p. 793 143. DEM Study of a Mixer for Core Manufacturing System - p. 799 144. Global Uncertainty and Sensitivity Analysis for Robust Design of a Rotary Kiln Process - p. 805 145. A novel scenario aggregation framework based on network community detection methods - p. 811 146. A Fuzzy Analytic Hierarchy Process (FAHP) Approach to Multi-Objective Optimisation of Oil Palm Value Chains - p. 817 147. Numerical Simulation of Forced Convection in a Microchannel with Realistic Roughness of 3D Printed Surface - p. 823 148. Optimization of a large-scale biorefinery problem by decomposition - p. 829 149. Planning of Supply Chains Threatened by Extreme Events: Novel Heuristic and Application to Industry Case Studies - p. 835 150. Turbulent flow modeling in continuous oscillatory flow baffled reactor using STAR CCM + - p. 841 151. Overpotentials in Water Electrolysis: In-Silico Comparison of PEM-cell and GAP-cell performance - p. 847 152. Study on the formation of chemical wave patterns for the Belousov–Zhabotinsky reaction system - p. 853 153. Efficient design of intensified extractive distillation processes based on a hybrid optimization approach - p. 859 154. Flux Balance Analysis Incorporating a Coarse-grained Proteome Constraint for Predicting Overflow Metabolism in Escherichia Coli - p. 865 155. Adjoint system method in shape optimization of some typical fluid flow patterns - p. 871 156. Integrated white-box models for designing freezing processes of human induced pluripotent stem cells considering diversity within a container - p. 877 157. Improving the prediction of multi-component tablet properties from pure component parameters - p. 883 158. Total Organic Carbon Prediction with Artificial Intelligence Techniques - p. 889 159. On the Design and Implementation of a Process Modelling Language for Uncertainty - p. 895 160. Simulation of Food Waste Pyrolysis for the Production of Biochar: A Qatar Case Study - p. 901 161. The robust pooling problem - p. 907 162. A model identification approach for the evaluation of plant efficiency - p. 913 163. Reinforcement Learning for Batch-to-Batch Bioprocess Optimisation - p. 919 164. A primal bounding approach for multistage stochastic programs of resource-constrained planning and scheduling with stochastic task success - p. 925 165. Rigorous Bayesian Inference VS New Approximate Strategies for Estimation of the Probability Distribution of the Parameters of DAE Models - p. 931 166. Deterministic Global Process Optimization: Flash Calculations via Artificial Neural Networks - p. 937 167. An Efficient MILP-Based Decomposition Strategy for Solving Large-Scale Scheduling Problems in the Offshore Oil and Gas Industry - p. 943 168. Computer-aided Design of Solvent Blends for the Cooling and Anti-solvent Crystallisation of Ibuprofen - p. 949 169. Process model validation and analysis for intensification of an industrial scale process - p. 955 170. BIOPRO-Sim: A benchmark simulation model for bio-manufacturing processes - p. 961 171. Development of the Texas A&M Superfund Research Program Computational Platform for Data Integration, Visualization, and Analysis - p. 967 172. Modelling Paraffin Wax Deposition Using Aspen HYSYS and MATLAB - p. 973 173. Optimal distributed load allocation and resource utilisation in evaporation plants - p. 979 174. Modelling and optimal operation of a natural gas fired natural draft heater - p. 985 175. Molecular Modelling of Co-processing Biomass Pyrolysis Oil with Vacuum Gasoil in an Oil Refinery Fluid Catalytic Cracking Unit - p. 991 176. A Chance-Constrained Nonlinear Programming Approach for Equipment Design Under Uncertainty - p. 997 177. Sustainable Strategic Planning for a National Natural Gas Energy System Accounting for Unconventional Sources - p. 1003 178. Modelling Full Cycles of Carbonation-Calcination for Calcium Looping Process Simulation - p. 1009 179. Determination of the optimal distribution of active centers in a multifunctional catalyst pellet using global searching combined with reduced-order modeling approach - p. 1015 180. Sequential and Simultaneous Optimization Strategies for Increased Production of Monoclonal Antibodies - p. 1021 181. Operating regime model based multi-objective sensor placement for data reconciliation - p. 1027 182. Fouling Modelling in Crude Oil Heat Exchanger Networks using Data Reconciliation and Estimation of Unmeasured Process Variables - p. 1033 183. Reduced model-based global optimisation of large-scale steady state nonlinear systems - p. 1039 184. Advanced Model Design Based on Intelligent System Characterization And Problem Definition - p. 1045 185. Probabilistic Design Space - p. 1051 186. Modeling Impacts of Tracking on Greenhouse Gas Emissions from Photovoltaic Power - p. 1057 187. Recent Advances in Graph-Based Abstractions for Modeling and Simulating Complex Systems - p. 1063 188. Spatio-Temporal Control of Nutrient Pollution from Organic Waste - p. 1069 189. Optimal design and planning multi resource-based energy integration in process industries - p. 1075 190. Heat-integrated water allocation network design: a novel hyperstructure and sequential solution strategy for industrial applications - p. 1081 191. Describing CO2-Absorbent Propertiesin AspenPlus® - p. 1087 192. Immune system modelling in case of a septic shock - p. 1093 193. More power to the individual modeller using ontologies - p. 1099 194. Relative Optimality Index for Evaluation of the Approximate Methods for Synthesis of Flexible Processes under Uncertainty - p. 1105 195. Time Resolved Sensitivity & Identifiability Analysis for Directed Parametrization of Highly Dynamic Models - p. 1111 196. On Robustness of Mixed-Integer reformulations of Generalized Disjunctive Programs - p. 1117 197. A Comparison of Data Reconciliation Tools for Modelling Heat Recovery - p. 1123 198. Assessment of the dominant factors during hydroprocessing stabilization - p. 1129 199. Copyright - p. iv 200. Process control and operations - p. iv 201. Fuzzy Control Applied to Combustion in Sugarcane Bagasse Boilers - p. 1135 202. Dynamics and Control of a Fully Heat-Integrated Complex Distillation Column - p. 1141 203. The impact of sustainable supply chain on waste-to-energy operations - p. 1147 204. Automating a shuttle-conveyor for multi-stockpile level control - p. 1153 205. A simple modeling approach to control emulsion layers in gravity separators - p. 1159 206. Improving Waste Water Treatment Plant Operation by Ammonia Based Aeration and Return Activated Sludge Control - p. 1165 207. Combining the Advantages of Discrete- and Continuous-time MIP Scheduling Models - p. 1171 208. Decision-making of online rescheduling procedures using neuroevolution of augmenting topologies - p. 1177 209. Optimal short-term Scheduling of Industrial Packing Facilities - p. 1183 210. Deciphering Latent Uncertainty Sources with Principal Component Analysis for Adaptive Robust Optimization - p. 1189 211. Incipient Fault Detection, Diagnosis, and Prognosis using Canonical Variate Dissimilarity Analysis - p. 1195 212. One-point temperature control of reactive distillation: A thermodynamics-based assessment - p. 1201 213. The Effect of Indirect GHG Emissions Costs on the Optimal Water and Energy Supply Systems - p. 1207 214. Short-term Scheduling of a Multipurpose Batch Plant Considering Degradation Effects - p. 1213 215. Real-time determination of optimal switching times for a H2 production process with CO2 capture using Gaussian Process Regression models - p. 1219 216. An Advanced Data-Centric Multi-Granularity Platform for Industrial Data Analysis - p. 1225 217. Optimal Operation and Control of Fluidized Bed Membrane Reactors for Steam Methane Reforming - p. 1231 218. Stochastic nonlinear model predictive control of a batch fermentation process - p. 1237 219. Control structure designfora CO 2 -refrigeration system with heat recovery - p. 1243 220. Real-Time Optimisation of Closed-Loop Processes Using Transient Measurements - p. 1249 221. Process Dynamic Analysis and Control Strategy for COGEN option Used for Flare Utilization - p. 1255 222. Efficient robust nonlinear model predictive control via approximate multi-stage programming: A neural networks based approach - p. 1261 223. Filter-based Constraints to Easier Plant Feasibility in Modifier Adaptation Schemes - p. 1267 224. Real-time feasible model-based crystal size and shape control of crystallization processes - p. 1273 225. Integration of Max-Plus-Linear Scheduling and Control - p. 1279 226. Nonlinear Model Predictive Control of Haemodialysis - p. 1285 227. Development of Guidelines for Optimal Operation of a Cogeneration System - p. 1291 228. On the Optimization of Production Scheduling in Industrial Food Processing Facilities - p. 1297 229. A Stacked Auto-Encoder Based Fault Diagnosis Model for Chemical Process - p. 1303 230. Multi-objective optimization approach to design and planning hydrogen supply chain under uncertainty: A Portugal study case - p. 1309 231. Morris screening for FMECA of valve failure modes on offshore gas reinjection - p. 1315 232. Optimal Maintenance Scheduling for Washing of Compressors to Increase Operational Efficiency - p. 1321 233. A Quality-by-Control Approach in Pharmaceutical Continuous Manufacturing of Oral Solid Dosage via Direct Compaction - p. 1327 234. Dynamic transitions in a reactive distillation column for the production of silicon precursors - p. 1333 235. Dynamics and control of a heat pump assisted azeotropic dividing-wall column (HP-A-DWC) for biobutanol purification - p. 1339 236. Closed-loop dynamic real-time optimization of a batch graft polymerization reactor - p. 1345 237. Application of cyclic operation to acetic / water separation - p. 1351 238. Control analysis of batch reactive distillation column with intermittent fed - p. 1357 239. New Methodology for Bias Identification and Estimation – Application to Nuclear Fuel Recycling Process - p. 1363 240. A Blockchain Framework for Containerized Food Supply Chains - p. 1369 241. Data-Based Robust Model Predictive Control Under Conditional Uncertainty - p. 1375 242. Centralised versus localised supply chain management using a flow configuration model - p. 1381 243. An improved approach to scheduling multipurpose batch processes with conditional sequencing - p. 1387 244. Electroencephalogram based Biomarkers for Tracking the Cognitive Workload of Operators in Process Industries - p. 1393 245. A Data-Driven Robust Optimization Approach to Operational Optimization of Industrial Steam Systems under Uncertainty - p. 1399 246. Synthesis technology for failure analysis and corrective actions in process systems engineering - p. 1405 247. Challenges in Decision-Making Modelling for New Product Development in the Pharmaceutical Industry - p. 1411 248. Extension of a Particle Filter for Bioprocess State Estimation using Invasive and Non-Invasive IR Measurements - p. 1417 249. Design of Multi Model Fractional Controllers for Nonlinear Systems: An Experimental Investigation - p. 1423 250. Optimal Operation and Control of Heat-to-Power Cycles: a New Perspective using a Systematic Plantwide Control Approach - p. 1429 251. Novel strategies for predictive particle monitoring and control using advanced image analysis - p. 1435 252. Integrating Simulation and Optimization for Process Planning and Scheduling Problems - p. 1441 253. CAPE-PSE in sustainable development and food industry - p. 1446 254. A Neural Network-Based Framework to Predict Process-Specific Environmental Impacts - p. 1447 255. Multi-objective spatio-temporal optimisation for simultaneous planning, design and operation of sustainable and efficient value chains for rice crop - p. 1453 256. Dynamic Optimisation and Visualisation of Industrial Beer Fermentation with Explicit Heat Transfer Dynamics - p. 1459 257. Statistical Modelling for Optimisation of Mash Separation Efficiency in Industrial Beer Production - p. 1465 258. End-of-Pipe Zero Liquid Discharge Networks for different brine water qualities - p. 1471 259. A PLSR Model for Consumer Preference Prediction of Yoghurt from Sensory Attributes Profiles - p. 1477 260. Fouling and Cleaning of Plate Heat Exchangers for Milk Pasteurisation: A Moving Boundary Model - p. 1483 261. Satellite based Vegetation Indices variables for Crop Water Footprint Assessment - p. 1489 262. Life Cycle Assessment of Petroleum Coke Gasification to Fischer-Tropsch Diesel - p. 1495 263. A Systematic Parameter Study on Film Freeze Concentration - p. 1501 264. Simulation-based reinforcement learning for delivery fleet optimisation in CO2 fertilisation networks to enhance food production systems - p. 1507 265. Systematic decision-support methodology for identifying promising platform technologies towards circular economy - p. 1513 266. A systemic approach for agile biorefineries - p. 1519 267. Targeting material exchanges in industrial symbiosis networks - p. 1525 268. Modeling and Multi-Objective Optimization of Syngas Fermentation in a Bubble Column Reactor - p. 1531 269. Modeling of multi-effect desalination process operated with thermosolar energy applied to the northeastern Brazil - p. 1537 270. A stochastic environmental model to deal with uncertainty in life cycle impact assessment - p. 1543 271. Green Supply Chain: Integrating Financial Risk Measures while Monetizing Environmental Impacts - p. 1549 272. Life cycle assessment of Jatropha jet biodiesel production in China conditions - p. 1555 273. Life-Cycle Environmental Impact Assessment of the Alternate Subsurface Intake Designs for Seawater Reverse Osmosis Desalination - p. 1561 274. Optimization of biofuel supply chain design via a water-energy-food nexus framework - p. 1567 275. A multiscale model approach for cell growth for lipids and pigments production by Haematococcus pluvialis under different environmental conditions. - p. 1573 276. Ecosystem Services Valuation and Ecohydrological Management in Salt Lakes with Advanced Dynamic Optimisation Strategies - p. 1579 277. Life cycle design of indoor hydroponic horticulture considering energy-water-food nexus - p. 1585 278. Giving added value to products from biomass: the role of mathematical programming in the product-driven process synthesis framework - p. 1591 279. Bottom-up method for potential estimation of energy saving measures - p. 1597 280. Generating Efficient Wastewater Treatment Networks: an integrated approach comprising of contaminant properties, technology suitability, plant design, and process optimization - p. 1603 281. A process systems engineering approach to designing a solar/biomass hybrid energy system for dairy farms in Argentina - p. 1609 282. Modelling and Simulation of Supercritical CO2 Oil Extraction from Biomass - p. 1615 283. Optimisation of the integrated water – energy systems: a review with a focus in Process Systems Engineering - p. 1621 284. CAPE-PSE in energy transition - p. 1626 285. On the role of H2 storage and conversion for wind power production in the Netherlands - p. 1627 286. An MPEC model for Strategic Offers in a Jointly Cleared Energy and Reserve Market under Stochastic Production - p. 1633 287. Model-Based Bidding Strategies for Simultaneous Optimal Participation in Different Balancing Markets - p. 1639 288. Optimal CSP-waste based polygeneration coupling for constant power production - p. 1645 289. A Multiperiod Optimisation Approach to Enhance Oil Field Productivity during Secondary Petroleum Production - p. 1651 290. Fast Fourier Transforms for Microgrid Climate Computing - p. 1657 291. A Financial Accounting based Model of Carbon Footprinting: Built Environment Example - p. 1663 292. Population Balance Equation Applied to Microalgae Filtration - p. 1669 293. Contract Settlements for Exchanging Utilities through Automated Negotiations between Prosumers in Eco-Industrial Parks using Reinforcement Learning - p. 1675 294. Exergoeconomic Analysis for a Flexible Dry Reforming Power Plant with Carbon Capture for Improved Energy Efficiency - p. 1681 295. Variations of the shrinking core model for effective kinetics modeling of the gas hydrate-based CO2 capture process - p. 1687 296. Optimization of semi-permeable membrane systems for biogas upgrading - p. 1693 297. System-Level Optimisation of Combined Power and Desalting Plants - p. 1699 298. Consequential Life Cycle Analysis for Food-Water- Energy-Waste Nexus - p. 1705 299. The Optimization of Heliostat Canting in a Solar Power Tower Plant - p. 1711 300. On-grid Hybrid Power System and Utility Network planning to supply an Eco-Industrial Park with dynamic data - p. 1717 301. Evaluating the Benefits of LNG Procurement through Spot Market Purchase - p. 1723 302. Optimal design of biomass supply chains with integrated process design - p. 1729 303. Optimisation of the integrated water – energy systems in small group of islands communities - p. 1735 304. Novel Methodology for Cogeneration Targeting with Optimum Steam Level Placement - p. 1741 305. From renewable energy to ship fuel: ammonia as an energy vector and mean for energy storage - p. 1747 306. Are renewables really that expensive? The impact of uncertainty on the cost of the energy transition - p. 1753 307. Comparative analysis of gasification and reforming technologies for the syngas production - p. 1759 308. Model-based decision-support for waste-to-energy pathways in New South Wales, Australia - p. 1765 309. Optimal Oversizing and Operation of the Switchable Chlor-Alkali Electrolyzer for Demand Side Management - p. 1771 310. The use of optimization tools for the Hydrogen Circular Economy - p. 1777 311. CAPE-PSE in hi-tech micro, nano-devices and processes - p. 1782 312. A dynamic model for automated control of directed self-assembly of colloidal particles at low densities - p. 1783 313. Structured millichannel multiphase reactors - p. 1789 314. Design of Microreactor Systems with Minimization of Flow Pulsation - p. 1795 315. Process Intensification and Miniaturization of Chemical and Biochemical Processes - p. 1801 316. Modelling of Microfluidic Devices for Analysis of Radionuclides - p. 1807 317. Education in CAPE-PSE and knowledge transfer - p. 1812 318. High-quality blend scheduling solution for sizing, selecting, sequencing, slotting and spotting in the processing industries - p. 1813 319. Flexible and efficient solution for control problems of chemical laboratories - p. 1819 320. Facilitating learning by failure through a pedagogical model-based tool for bioprocesses - p. 1825 321. Author Index - p. 1831
The 29th European Symposium on Computer Aided Process Engineering, contains the papers presented at the 29th European Symposium of Computer Aided Process Engineering (ESCAPE) event held in Eindhoven, The Netherlands, from June 16-19, 2019. It is a valuable resource for chemical engineers, chemical process engineers, researchers in industry and academia, students, and consultants for chemical industries.
1. Cover image - p. xxiii 2. Title page - p. xxiii 3. Table of Contents - p. xxiii 4. Copyright - p. xxiii 5. Preface - p. xxiii 6. Organizing & Scientific committees - p. xxv 7. Plenary and Keynotes Lectures - p. xxvii 8. Economic Nonlinear Model Predictive Control of Multi-Product Air Separation Processes - p. 1 9. From Single Process Simulation and Optimization to Decision Making Based on a Multitude of Solutions - p. 7 10. A Framework for the Integration of Holistic Sustainability Assessment in Computer-Aided Molecular Design - p. 13 11. Iterative Medium-Term Production Scheduling of an Industrial Formulation Plant - p. 19 12. Towards Model-Based Optimization for Quality by Design in Biotherapeutics Production - p. 25 13. Review of override control methods - p. 31 14. A comparison of the performance of multi-objective optimization methodologies for solvent design - p. 37 15. Automated open-loop control of directed self-assembly with multiple electrokinetic actuators in microfluidic devices - p. 43 16. Automatic synthesis of distillation processes for the separation of azeotropic multi-component systems - p. 49 17. Design and Planning of Agri-Food Supply Chains - p. 55 18. An Explicit Online Resource-Task Network Scheduling Formulation to Avoid Scheduling Nervousness - p. 61 19. Optimizing Return on Investment in Biomass Conversion Networks under Uncertainty Using Data-Driven Adaptive Robust Optimization - p. 67 20. Towards a systematic framework for the synthesis of operable process intensification systems - application to reactive distillation systems - p. 73 21. Optimisation and control of a distributed energy resource network using Internet-of-Things technologies - p. 79 22. Engineering success: What does it take to get PSE technologies used? - p. 85 23. Component based development of computer-aided tools for different applications - p. 91 24. Predictive LCA - a systems approach to integrate LCA decisions ahead of design - p. 97 25. Energy System Modelling in support of the Energy Transition - p. 103 26. Process Systems Engineering from an industrial and academic perspective - p. 109 27. Process design meets sustainability: overview on the use of modelling tools for process design and sustainability assessment at Corbion - p. 115 28. New MINLP Formulations for Flexibility Analysis for Measured and Unmeasured Uncertain Parameters - p. 121 29. Mathematical process modelling past, present and future – a personal perspective - p. 127 30. Process-product synthesis, design and integration - p. 132 31. Simultaneous design and controllability optimization for the reaction zone for furfural bioproduction - p. 133 32. Design and Optimization of Azeotropic and Extractive Distillation to Purify Furfural Considering Safety, Environmental and Economic Issues. - p. 139 33. Revisiting Classic Acetic Acid Synthesis: Optimal Hydrogen Consumption and Carbon Dioxide Utilization - p. 145 34. Innovative application of statistical analysis for the optimization of CO2 absorption from flue gas with ionic liquid - p. 151 35. Synthesis, Design and Optimization of Schemes to Produce 2, 3-Butanediol Considering Economic, Environmental and Safety issues - p. 157 36. ORC on tour: Integrated design of dynamic ORC processes and working fluids for waste-heat recovery from heavy-duty vehicles - p. 163 37. Optimisation of multi effect distillation based desalination system for minimum production cost for freshwater - p. 169 38. A model-based approach for optimizing petroleum refinery configuration for heavy oil processing - p. 175 39. Performance Evaluation of Reverse Osmosis Brackish Water Desalination Plant with Different Recycled Ratios of Retentate - p. 181 40. Globally Optimal Design of Double Pipe Heat Exchangers using Local Properties and Discretized Models - p. 187 41. Optimization of Biogas to Syngas via Combined Super-Dry and Tri-Reforming. Analysis of Fischer-Tropsch Fuels Production - p. 193 42. Optimising European supply chains for carbon capture, transport and sequestration, including uncertainty on geological storage availability - p. 199 43. Applying a Sustainability Metric in Energy, Water and Food Nexus Applications; A Biomass Utilization Case Study to Improve Investment Decisions - p. 205 44. Technoeconomic MINLP Optimisation of Liquid-Liquid Extraction (LLE) Cascades for Continuous Pharmaceutical Manufacturing (CPM) of Atropine - p. 211 45. Multi-product reactive distillation process for higher acrylates production - p. 217 46. A point estimate method-based back-off approach to robust optimization: application to pharmaceutical processes - p. 223 47. Design and Operation Optimization for Water and Power Cogeneration System by Reverse Osmosis and Renewable Energy Technologies - p. 229 48. Modelling of extractive heterogeneous-azeotropic distillation in dividing wall column - p. 235 49. Optimization of an Integrated First- and Second-Generation Ethanol Production Plant with Focus on Hydrolysis Parameters - p. 241 50. Optimization of seaweed-based biorefinery with zero carbon emissions potential - p. 247 51. Optimal design for integrated macroalgae-based biorefinery via mixed alcohol synthesis - p. 253 52. Global Optimization of Counter Current Gasketed Plate Heat Exchanger - p. 259 53. An optimization model for a biorefinery system based on process design and logistics - p. 265 54. Design of smart liquid-liquid extraction columns for downstream separations of biopharmaceuticals using deep Q-learning algorithm - p. 271 55. Process design and techno-economic analysis of a pineapple wine production plant under the context of the Choco-Colombia region - p. 277 56. Optimisation of Aqueous Two-Phase Systems - p. 283 57. Development of a biorefinery scheme to produce biofuels from waste cooking oil - p. 289 58. A network model-based optimisation analysis for the utilisation of CO2 in Qatar’s chemical industries - p. 295 59. Superstructure Optimization for the Production of Fuels, Fertilizers and Power using Biomass Gasification - p. 301 60. Techno-Economic-Environmental Study for Recovery of Novel Water Source within a Power Plant - Desalination Complex - p. 307 61. Molecular tracking: A novel approach for multicomponent distillation column design - p. 313 62. Development of a Model-Based Quality-by-Control Framework for Crystallization Design - p. 319 63. Towards development of a decision support tool for conceptual design of wastewater treatment plants using stochastic simulation optimization - p. 325 64. Targeting of sustainable chemical processes using data envelopment analysis: application to liquid fuels for transportation - p. 331 65. Production scheduling of semi-continuous milk processing facility - p. 337 66. Fast Bypass Selection Method during the Heat Exchanger Network Synthesis - p. 343 67. Integrating Oil Refineries and Bio-refineries: Upgrading Acetone, Butanol and Ethanol to High-Value Products - p. 349 68. Heat-Integrated Reactive distillation processes to produce Ethyl Levulinate: Design and Optimization including Environmental, Safety and Economics Aspects - p. 355 69. Risk-conscious approach to optimizing bioenergy investments in the Brazilian sugarcane industry - p. 361 70. Production of chemicals from syngas: an enviro-economic model-based investigation - p. 367 71. A new index for chemical process design considering risk analysis and controllability - p. 373 72. An MILP model for safe multi-floor process plant layout - p. 379 73. A Generalized, Nonsmooth Operator for Process Integration - p. 385 74. Analysis of Process Alternatives for Energy-Efficient Bioethanol Downstream Processing - p. 391 75. A Model based analysis in applying Anderson–Schulz–Flory (ASF) equation with CO2 Utilisation on the Fischer Tropsch Gas-to-liquid Process - p. 397 76. Scalable manufacturing of nanostructured materials by atomic layer deposition in fluidized bed reactors - p. 403 77. Effect of Non-Ideal Kinetics on Hybrid Reactive Distillation Models for Selectivity Engineering - p. 409 78. Integrated Design of Solvents and Processes based on Reaction Kinetics from Quantum Chemical Prediction Methods - p. 415 79. Novel refrigeration cycle configurations for performance improvements in LNG processes at small scale - p. 421 80. Involving the Water-Energy-Food Nexus in Integrating Low-Income and Isolated Communities - p. 427 81. Integration of Consumer Preferences and Heuristic Knowledge in the Design of Formulated Products: Application to a Cosmetic Emulsion - p. 433 82. Economic Study of the Urea Alcoholysis Process for Dimethyl Carbonate Production - p. 439 83. Effect of Ambient Conditions on Boil Off Gas Generation in LNG regasification terminals - p. 445 84. An MPCC Reactive Distillation Optimization Model for Multi-Objective Fischer–Tropsch Synthesis - p. 451 85. Techno-economic analysis of alternative reactive purification technologies in the lactic acid production process. - p. 457 86. Optimal design of post combustion CO2 capture processes based on phase-change solvents - p. 463 87. Optimization of a hydroformulation process in a thermomorphic solvent system using a commercial steady-state process simulator and a memetic algorithm - p. 469 88. Exergy analysis for energy integration in a bioethanol production process to determine heat exchanger networks feasibility - p. 475 89. ProCAFD: Computer-aided Tool for Sustainable Process Synthesis, Intensification and Hybrid solutions - p. 481 90. A multi-objective multi-period optimization of carbon integration networks in industrial parks - p. 487 91. Improved problem constraints modeling based using classification - p. 493 92. Bioethanol Production with Cyanobacteria by a Two-Stage Fermentation Strategy - p. 499 93. Application of plate heat exchangers into heat exchanger networks retrofit with fixed structure - p. 505 94. Clustering alternative product formulations using graphs - p. 511 95. Analysis of the Tri-Reforming of Methane in a Membrane Reactor - p. 517 96. Design of a novel sour water stripping unit - p. 523 97. Techno-economic Assessment of Future Generation IGCC Processes with Control on Greenhouse Gas Emissions - p. 529 98. Synthesis of Solar Heat Network for Preheating of Industrial Process Streams - p. 535 99. Methods, models and computational tools for PSE - p. 540 100. On the implementation of generalized polynomial chaos in dynamic optimization under stochastic uncertainty: a user perspective - p. 541 101. Optimal dose administration of renally excreted drugs - p. 547 102. Automating HAZOP studies using D-higraphs - p. 553 103. A Novel Optimizable Inherent Safety Index Based on Fuzzy Logic - p. 559 104. Optimization under uncertainty of melatonin dosing for critically ill patients - p. 565 105. Optimization of a shell-and-tube heat exchanger using the grey wolf algorithm - p. 571 106. Optimization Under Uncertainty Based on a Data-driven Model for a Chloralkali Electrolyzer Cell - p. 577 107. Parameter Estimation for Thermodynamic Models Using an Identifiability Analysis and Subset Selection - p. 583 108. Evaluation of Discretization Methods for Modeling the Chloralkali Membrane Process - p. 589 109. A steady-state and dynamic simulation tool for solid oxide fuel cell operation applications - p. 595 110. Thermal conductivity prediction of molten salt-based nanofluids for energy storage applications - p. 601 111. Nanoparticle behaviour in multiphase turbulent channel flow - p. 607 112. Multi-objective optimisation of chemical processes via improved genetic algorithms: A novel trade-off and termination criterion - p. 613 113. DyOS - A Framework for Optimization of Large-Scale Differential Algebraic Equation Systems - p. 619 114. Rate-based modelling and simulation of pilot scale distillation column - p. 625 115. Computer-Assisted Experiments for the Identification of the Two-Phase Viscosity of Fluids - p. 631 116. Increasing the Reliability of Parameter Estimates by Iterative Model-based Design of Experiments Using a Flowsheet-Simulator - p. 637 117. Estimating mixture properties from batch distillation using semi-rigorous and rigorous models - p. 643 118. An MILP Approach for Short-term Scheduling of Batch Operations - p. 649 119. Synthesis and optimization of refinery hydrogen network using surrogate models - p. 655 120. Real-time design space description in pharmaceutical manufacturing - p. 661 121. Flexibility Assessment of a Distillation Train: Nominal vs Perturbated Conditions Optimal Design - p. 667 122. Dynamic Modelling and Simulation of Chinese Hamster Ovary (CHO) Cell Fermentation for Advanced Biopharmaceutical Manufacturing - p. 673 123. Statistical diagnosis of process-model mismatch by means of the Lagrange multiplier test - p. 679 124. Optimal design of experiments for the identification of kinetic models of 5-hydroxymethylfurfural hydrogenation - p. 685 125. On the Solution of the Smoluchowski Coagulation Equation Using a Conservative Discretization Approach (CDA) - p. 691 126. Coordination of multiple production and utility systems in a multi-leader multi-follower Stackelberg game - p. 697 127. From peak power prices to seasonal storage: Long-term operational optimization of energy systems by time-series decomposition - p. 703 128. Scale-up Modeling of a Pharmaceutical Antisolvent Crystallization via a Hybrid Method of Computational Fluid Dynamics and Compartmental Modeling - p. 709 129. Modelling of bubble column hydrodynamics using CFD and SQMOM as a population balance solver - p. 715 130. Single-shooting optimization of an industrial process through co-simulation of a modularized Aspen Plus Dynamics model - p. 721 131. A Discrete-time MILP Formulation for the Optimal Scheduling of Maintenance Tasks on Oil and Gas Wells and Surface Facilities - p. 727 132. Optimal design of multi-stage depressurization systems using dynamic modelling - p. 733 133. Innovative mapping method for screening reactive distillation designs - p. 739 134. Integrated Process and Controller Design Software Tool – ProCACD - p. 745 135. Computational Fluid Dynamics of Rectangular Monolith Reactor vs. Packed-Bed Column for Sorption-Enhanced Water-Gas Shift - p. 751 136. A novel process monitoring approach based on Feature Points Distance Dynamic Autoencoder - p. 757 137. A Framework for Multi-level Life Cycle Analysis of the Energy System - p. 763 138. Nonlinear dynamic analysis of chemical engineering processes described by differential-algebraic equations systems - p. 769 139. Parameter Estimation for Thermal Runaway of Li-ion cells: a Gaussian Process approach - p. 775 140. Improved Design of Experiments for Identification of MIMO Systems - p. 781 141. Machine Learning of Molecular Classification and Quantum Mechanical Calculations - p. 787 142. Comparative CFD analysis of thermal energy storage materials in photovoltaic/thermal panels - p. 793 143. DEM Study of a Mixer for Core Manufacturing System - p. 799 144. Global Uncertainty and Sensitivity Analysis for Robust Design of a Rotary Kiln Process - p. 805 145. A novel scenario aggregation framework based on network community detection methods - p. 811 146. A Fuzzy Analytic Hierarchy Process (FAHP) Approach to Multi-Objective Optimisation of Oil Palm Value Chains - p. 817 147. Numerical Simulation of Forced Convection in a Microchannel with Realistic Roughness of 3D Printed Surface - p. 823 148. Optimization of a large-scale biorefinery problem by decomposition - p. 829 149. Planning of Supply Chains Threatened by Extreme Events: Novel Heuristic and Application to Industry Case Studies - p. 835 150. Turbulent flow modeling in continuous oscillatory flow baffled reactor using STAR CCM + - p. 841 151. Overpotentials in Water Electrolysis: In-Silico Comparison of PEM-cell and GAP-cell performance - p. 847 152. Study on the formation of chemical wave patterns for the Belousov–Zhabotinsky reaction system - p. 853 153. Efficient design of intensified extractive distillation processes based on a hybrid optimization approach - p. 859 154. Flux Balance Analysis Incorporating a Coarse-grained Proteome Constraint for Predicting Overflow Metabolism in Escherichia Coli - p. 865 155. Adjoint system method in shape optimization of some typical fluid flow patterns - p. 871 156. Integrated white-box models for designing freezing processes of human induced pluripotent stem cells considering diversity within a container - p. 877 157. Improving the prediction of multi-component tablet properties from pure component parameters - p. 883 158. Total Organic Carbon Prediction with Artificial Intelligence Techniques - p. 889 159. On the Design and Implementation of a Process Modelling Language for Uncertainty - p. 895 160. Simulation of Food Waste Pyrolysis for the Production of Biochar: A Qatar Case Study - p. 901 161. The robust pooling problem - p. 907 162. A model identification approach for the evaluation of plant efficiency - p. 913 163. Reinforcement Learning for Batch-to-Batch Bioprocess Optimisation - p. 919 164. A primal bounding approach for multistage stochastic programs of resource-constrained planning and scheduling with stochastic task success - p. 925 165. Rigorous Bayesian Inference VS New Approximate Strategies for Estimation of the Probability Distribution of the Parameters of DAE Models - p. 931 166. Deterministic Global Process Optimization: Flash Calculations via Artificial Neural Networks - p. 937 167. An Efficient MILP-Based Decomposition Strategy for Solving Large-Scale Scheduling Problems in the Offshore Oil and Gas Industry - p. 943 168. Computer-aided Design of Solvent Blends for the Cooling and Anti-solvent Crystallisation of Ibuprofen - p. 949 169. Process model validation and analysis for intensification of an industrial scale process - p. 955 170. BIOPRO-Sim: A benchmark simulation model for bio-manufacturing processes - p. 961 171. Development of the Texas A&M Superfund Research Program Computational Platform for Data Integration, Visualization, and Analysis - p. 967 172. Modelling Paraffin Wax Deposition Using Aspen HYSYS and MATLAB - p. 973 173. Optimal distributed load allocation and resource utilisation in evaporation plants - p. 979 174. Modelling and optimal operation of a natural gas fired natural draft heater - p. 985 175. Molecular Modelling of Co-processing Biomass Pyrolysis Oil with Vacuum Gasoil in an Oil Refinery Fluid Catalytic Cracking Unit - p. 991 176. A Chance-Constrained Nonlinear Programming Approach for Equipment Design Under Uncertainty - p. 997 177. Sustainable Strategic Planning for a National Natural Gas Energy System Accounting for Unconventional Sources - p. 1003 178. Modelling Full Cycles of Carbonation-Calcination for Calcium Looping Process Simulation - p. 1009 179. Determination of the optimal distribution of active centers in a multifunctional catalyst pellet using global searching combined with reduced-order modeling approach - p. 1015 180. Sequential and Simultaneous Optimization Strategies for Increased Production of Monoclonal Antibodies - p. 1021 181. Operating regime model based multi-objective sensor placement for data reconciliation - p. 1027 182. Fouling Modelling in Crude Oil Heat Exchanger Networks using Data Reconciliation and Estimation of Unmeasured Process Variables - p. 1033 183. Reduced model-based global optimisation of large-scale steady state nonlinear systems - p. 1039 184. Advanced Model Design Based on Intelligent System Characterization And Problem Definition - p. 1045 185. Probabilistic Design Space - p. 1051 186. Modeling Impacts of Tracking on Greenhouse Gas Emissions from Photovoltaic Power - p. 1057 187. Recent Advances in Graph-Based Abstractions for Modeling and Simulating Complex Systems - p. 1063 188. Spatio-Temporal Control of Nutrient Pollution from Organic Waste - p. 1069 189. Optimal design and planning multi resource-based energy integration in process industries - p. 1075 190. Heat-integrated water allocation network design: a novel hyperstructure and sequential solution strategy for industrial applications - p. 1081 191. Describing CO2-Absorbent Propertiesin AspenPlus® - p. 1087 192. Immune system modelling in case of a septic shock - p. 1093 193. More power to the individual modeller using ontologies - p. 1099 194. Relative Optimality Index for Evaluation of the Approximate Methods for Synthesis of Flexible Processes under Uncertainty - p. 1105 195. Time Resolved Sensitivity & Identifiability Analysis for Directed Parametrization of Highly Dynamic Models - p. 1111 196. On Robustness of Mixed-Integer reformulations of Generalized Disjunctive Programs - p. 1117 197. A Comparison of Data Reconciliation Tools for Modelling Heat Recovery - p. 1123 198. Assessment of the dominant factors during hydroprocessing stabilization - p. 1129 199. Copyright - p. iv 200. Process control and operations - p. iv 201. Fuzzy Control Applied to Combustion in Sugarcane Bagasse Boilers - p. 1135 202. Dynamics and Control of a Fully Heat-Integrated Complex Distillation Column - p. 1141 203. The impact of sustainable supply chain on waste-to-energy operations - p. 1147 204. Automating a shuttle-conveyor for multi-stockpile level control - p. 1153 205. A simple modeling approach to control emulsion layers in gravity separators - p. 1159 206. Improving Waste Water Treatment Plant Operation by Ammonia Based Aeration and Return Activated Sludge Control - p. 1165 207. Combining the Advantages of Discrete- and Continuous-time MIP Scheduling Models - p. 1171 208. Decision-making of online rescheduling procedures using neuroevolution of augmenting topologies - p. 1177 209. Optimal short-term Scheduling of Industrial Packing Facilities - p. 1183 210. Deciphering Latent Uncertainty Sources with Principal Component Analysis for Adaptive Robust Optimization - p. 1189 211. Incipient Fault Detection, Diagnosis, and Prognosis using Canonical Variate Dissimilarity Analysis - p. 1195 212. One-point temperature control of reactive distillation: A thermodynamics-based assessment - p. 1201 213. The Effect of Indirect GHG Emissions Costs on the Optimal Water and Energy Supply Systems - p. 1207 214. Short-term Scheduling of a Multipurpose Batch Plant Considering Degradation Effects - p. 1213 215. Real-time determination of optimal switching times for a H2 production process with CO2 capture using Gaussian Process Regression models - p. 1219 216. An Advanced Data-Centric Multi-Granularity Platform for Industrial Data Analysis - p. 1225 217. Optimal Operation and Control of Fluidized Bed Membrane Reactors for Steam Methane Reforming - p. 1231 218. Stochastic nonlinear model predictive control of a batch fermentation process - p. 1237 219. Control structure designfora CO 2 -refrigeration system with heat recovery - p. 1243 220. Real-Time Optimisation of Closed-Loop Processes Using Transient Measurements - p. 1249 221. Process Dynamic Analysis and Control Strategy for COGEN option Used for Flare Utilization - p. 1255 222. Efficient robust nonlinear model predictive control via approximate multi-stage programming: A neural networks based approach - p. 1261 223. Filter-based Constraints to Easier Plant Feasibility in Modifier Adaptation Schemes - p. 1267 224. Real-time feasible model-based crystal size and shape control of crystallization processes - p. 1273 225. Integration of Max-Plus-Linear Scheduling and Control - p. 1279 226. Nonlinear Model Predictive Control of Haemodialysis - p. 1285 227. Development of Guidelines for Optimal Operation of a Cogeneration System - p. 1291 228. On the Optimization of Production Scheduling in Industrial Food Processing Facilities - p. 1297 229. A Stacked Auto-Encoder Based Fault Diagnosis Model for Chemical Process - p. 1303 230. Multi-objective optimization approach to design and planning hydrogen supply chain under uncertainty: A Portugal study case - p. 1309 231. Morris screening for FMECA of valve failure modes on offshore gas reinjection - p. 1315 232. Optimal Maintenance Scheduling for Washing of Compressors to Increase Operational Efficiency - p. 1321 233. A Quality-by-Control Approach in Pharmaceutical Continuous Manufacturing of Oral Solid Dosage via Direct Compaction - p. 1327 234. Dynamic transitions in a reactive distillation column for the production of silicon precursors - p. 1333 235. Dynamics and control of a heat pump assisted azeotropic dividing-wall column (HP-A-DWC) for biobutanol purification - p. 1339 236. Closed-loop dynamic real-time optimization of a batch graft polymerization reactor - p. 1345 237. Application of cyclic operation to acetic / water separation - p. 1351 238. Control analysis of batch reactive distillation column with intermittent fed - p. 1357 239. New Methodology for Bias Identification and Estimation – Application to Nuclear Fuel Recycling Process - p. 1363 240. A Blockchain Framework for Containerized Food Supply Chains - p. 1369 241. Data-Based Robust Model Predictive Control Under Conditional Uncertainty - p. 1375 242. Centralised versus localised supply chain management using a flow configuration model - p. 1381 243. An improved approach to scheduling multipurpose batch processes with conditional sequencing - p. 1387 244. Electroencephalogram based Biomarkers for Tracking the Cognitive Workload of Operators in Process Industries - p. 1393 245. A Data-Driven Robust Optimization Approach to Operational Optimization of Industrial Steam Systems under Uncertainty - p. 1399 246. Synthesis technology for failure analysis and corrective actions in process systems engineering - p. 1405 247. Challenges in Decision-Making Modelling for New Product Development in the Pharmaceutical Industry - p. 1411 248. Extension of a Particle Filter for Bioprocess State Estimation using Invasive and Non-Invasive IR Measurements - p. 1417 249. Design of Multi Model Fractional Controllers for Nonlinear Systems: An Experimental Investigation - p. 1423 250. Optimal Operation and Control of Heat-to-Power Cycles: a New Perspective using a Systematic Plantwide Control Approach - p. 1429 251. Novel strategies for predictive particle monitoring and control using advanced image analysis - p. 1435 252. Integrating Simulation and Optimization for Process Planning and Scheduling Problems - p. 1441 253. CAPE-PSE in sustainable development and food industry - p. 1446 254. A Neural Network-Based Framework to Predict Process-Specific Environmental Impacts - p. 1447 255. Multi-objective spatio-temporal optimisation for simultaneous planning, design and operation of sustainable and efficient value chains for rice crop - p. 1453 256. Dynamic Optimisation and Visualisation of Industrial Beer Fermentation with Explicit Heat Transfer Dynamics - p. 1459 257. Statistical Modelling for Optimisation of Mash Separation Efficiency in Industrial Beer Production - p. 1465 258. End-of-Pipe Zero Liquid Discharge Networks for different brine water qualities - p. 1471 259. A PLSR Model for Consumer Preference Prediction of Yoghurt from Sensory Attributes Profiles - p. 1477 260. Fouling and Cleaning of Plate Heat Exchangers for Milk Pasteurisation: A Moving Boundary Model - p. 1483 261. Satellite based Vegetation Indices variables for Crop Water Footprint Assessment - p. 1489 262. Life Cycle Assessment of Petroleum Coke Gasification to Fischer-Tropsch Diesel - p. 1495 263. A Systematic Parameter Study on Film Freeze Concentration - p. 1501 264. Simulation-based reinforcement learning for delivery fleet optimisation in CO2 fertilisation networks to enhance food production systems - p. 1507 265. Systematic decision-support methodology for identifying promising platform technologies towards circular economy - p. 1513 266. A systemic approach for agile biorefineries - p. 1519 267. Targeting material exchanges in industrial symbiosis networks - p. 1525 268. Modeling and Multi-Objective Optimization of Syngas Fermentation in a Bubble Column Reactor - p. 1531 269. Modeling of multi-effect desalination process operated with thermosolar energy applied to the northeastern Brazil - p. 1537 270. A stochastic environmental model to deal with uncertainty in life cycle impact assessment - p. 1543 271. Green Supply Chain: Integrating Financial Risk Measures while Monetizing Environmental Impacts - p. 1549 272. Life cycle assessment of Jatropha jet biodiesel production in China conditions - p. 1555 273. Life-Cycle Environmental Impact Assessment of the Alternate Subsurface Intake Designs for Seawater Reverse Osmosis Desalination - p. 1561 274. Optimization of biofuel supply chain design via a water-energy-food nexus framework - p. 1567 275. A multiscale model approach for cell growth for lipids and pigments production by Haematococcus pluvialis under different environmental conditions. - p. 1573 276. Ecosystem Services Valuation and Ecohydrological Management in Salt Lakes with Advanced Dynamic Optimisation Strategies - p. 1579 277. Life cycle design of indoor hydroponic horticulture considering energy-water-food nexus - p. 1585 278. Giving added value to products from biomass: the role of mathematical programming in the product-driven process synthesis framework - p. 1591 279. Bottom-up method for potential estimation of energy saving measures - p. 1597 280. Generating Efficient Wastewater Treatment Networks: an integrated approach comprising of contaminant properties, technology suitability, plant design, and process optimization - p. 1603 281. A process systems engineering approach to designing a solar/biomass hybrid energy system for dairy farms in Argentina - p. 1609 282. Modelling and Simulation of Supercritical CO2 Oil Extraction from Biomass - p. 1615 283. Optimisation of the integrated water – energy systems: a review with a focus in Process Systems Engineering - p. 1621 284. CAPE-PSE in energy transition - p. 1626 285. On the role of H2 storage and conversion for wind power production in the Netherlands - p. 1627 286. An MPEC model for Strategic Offers in a Jointly Cleared Energy and Reserve Market under Stochastic Production - p. 1633 287. Model-Based Bidding Strategies for Simultaneous Optimal Participation in Different Balancing Markets - p. 1639 288. Optimal CSP-waste based polygeneration coupling for constant power production - p. 1645 289. A Multiperiod Optimisation Approach to Enhance Oil Field Productivity during Secondary Petroleum Production - p. 1651 290. Fast Fourier Transforms for Microgrid Climate Computing - p. 1657 291. A Financial Accounting based Model of Carbon Footprinting: Built Environment Example - p. 1663 292. Population Balance Equation Applied to Microalgae Filtration - p. 1669 293. Contract Settlements for Exchanging Utilities through Automated Negotiations between Prosumers in Eco-Industrial Parks using Reinforcement Learning - p. 1675 294. Exergoeconomic Analysis for a Flexible Dry Reforming Power Plant with Carbon Capture for Improved Energy Efficiency - p. 1681 295. Variations of the shrinking core model for effective kinetics modeling of the gas hydrate-based CO2 capture process - p. 1687 296. Optimization of semi-permeable membrane systems for biogas upgrading - p. 1693 297. System-Level Optimisation of Combined Power and Desalting Plants - p. 1699 298. Consequential Life Cycle Analysis for Food-Water- Energy-Waste Nexus - p. 1705 299. The Optimization of Heliostat Canting in a Solar Power Tower Plant - p. 1711 300. On-grid Hybrid Power System and Utility Network planning to supply an Eco-Industrial Park with dynamic data - p. 1717 301. Evaluating the Benefits of LNG Procurement through Spot Market Purchase - p. 1723 302. Optimal design of biomass supply chains with integrated process design - p. 1729 303. Optimisation of the integrated water – energy systems in small group of islands communities - p. 1735 304. Novel Methodology for Cogeneration Targeting with Optimum Steam Level Placement - p. 1741 305. From renewable energy to ship fuel: ammonia as an energy vector and mean for energy storage - p. 1747 306. Are renewables really that expensive? The impact of uncertainty on the cost of the energy transition - p. 1753 307. Comparative analysis of gasification and reforming technologies for the syngas production - p. 1759 308. Model-based decision-support for waste-to-energy pathways in New South Wales, Australia - p. 1765 309. Optimal Oversizing and Operation of the Switchable Chlor-Alkali Electrolyzer for Demand Side Management - p. 1771 310. The use of optimization tools for the Hydrogen Circular Economy - p. 1777 311. CAPE-PSE in hi-tech micro, nano-devices and processes - p. 1782 312. A dynamic model for automated control of directed self-assembly of colloidal particles at low densities - p. 1783 313. Structured millichannel multiphase reactors - p. 1789 314. Design of Microreactor Systems with Minimization of Flow Pulsation - p. 1795 315. Process Intensification and Miniaturization of Chemical and Biochemical Processes - p. 1801 316. Modelling of Microfluidic Devices for Analysis of Radionuclides - p. 1807 317. Education in CAPE-PSE and knowledge transfer - p. 1812 318. High-quality blend scheduling solution for sizing, selecting, sequencing, slotting and spotting in the processing industries - p. 1813 319. Flexible and efficient solution for control problems of chemical laboratories - p. 1819 320. Facilitating learning by failure through a pedagogical model-based tool for bioprocesses - p. 1825 321. Author Index - p. 1831