Despite being a relatively straightforward clinical diagnosis, recognition of hidradenitis suppurativa (HS) is highly variable, and clinical management is challenging and complex. Written by the world’s leading experts in HS, A Comprehensive Guide to Hidradenitis Suppurativa brings together up-to-date scientific evidence on the diagnosis, patho-mechanisms, comorbidities, and multi-faceted medical and surgical interventions for this debilitating condition—in one convenient reference.
Covers every aspect of this complex skin disorder: etiology, pathophysiology, epidemiology, medical, alternative therapies, a range of surgical options, laser treatments, and comorbidities.
Discusses specific patient populations such as children, women of childbearing potential, and pregnant and breastfeeding women. Because HS has higher prevalence in people of skin of color, this patient population is well-documented in the text.
Offers insights into multi-disciplinary care, patient support and education, patients at risk for rapid disease progression, and clinical and translational research.
Features procedural videos covering laser therapies, de-roofing procedures, excisions and closure techniques, cryoinsufflation techniques, and special wound care material selection and techniques.
Includes recent FDA-approved drugs as well as those drugs and therapies that show future promise.
Identifies evidence gaps that provide a springboard to the future innovations in HS care to come.
Edited and authored by global experts who have co-authored 2019 U.S. and Canadian guidelines on hidradenitis suppurativa.
1. Section 1: Introduction to Hidradenitis Suppurativa - p. page_xxi 2. 1: Historical Perspective on Hidradenitis Suppurativa - p. page_3 3. 2: Hidradenitis Suppurativa Epidemiology - p. page_10 4. 3: Clinical Manifestation and Phenotypes of Hidradenitis Suppurativa - p. page_18 5. 4: Hidradenitis Suppurativa Differential Diagnosis and Mimickers - p. page_27 6. 5: Histopathology of the Pilosebaceous Unit and Interstitium of Hidradenitis Suppurativa - p. page_37 7. 6: Imaging Techniques in Hidradenitis Suppurativa and Comorbidities - p. page_45 8. 7: Clinical Evaluation - p. page_62 9. 8: Comorbidities and Systemic Associations - p. page_69 10. 9: Disease Complications - p. page_77 11. Section 2: Pathogenesis - p. page_86 12. 10: Follicular Occlusion and Inflammation - p. page_89 13. 11: Microbiota Perturbations in Hidradenitis Suppurativa - p. page_100 14. 12: Genetics and Epigenetics of Hidradenitis Suppurativa - p. page_105 15. Section 3: Clinician’s Corner - p. page_116 16. 13: Disease Evaluation and Outcome Measures - p. page_121 17. 14: Overview and Comparison of Hidradenitis Suppurativa Management Guidelines - p. page_130 18. 15: Topical Therapeutics - p. page_145 19. 16: Systemic Antibiotics in Hidradenitis Suppurativa - p. page_155 20. 17: Non-Antibiotic and Non-Biologic Systemic Therapeutics - p. page_167 21. 18: Targeted Therapeutics: Biologics, Small Molecules - p. page_182 22. 19: Pain and Itch Control - p. page_191 23. 20: Dressings and Wound Care Supplies for Hidradenitis Suppurativa - p. page_201 24. 21: Quality of Life - p. page_208 25. 22: Office-Based Non-Excision Procedures - p. page_215 26. 23: Operative Techniques for Hidradenitis Suppurativa - p. page_226 27. 24: Office-Based Excision for Hidradenitis Suppurativa: A Surgeon’s Decades-Long Experience - p. page_233 28. 25: Laser and Light Treatments for Hidradenitis Suppurativa - p. page_248 29. 26: Hidradenitis Suppurativa—Other Procedural Treatments - p. page_254 30. 27: Lifestyle Modifications - p. page_264 31. 28: Complementary and Alternative Medicine - p. page_273 32. Section 4: Special Populations - p. page_282 33. 29: Pediatric Hidradenitis Suppurativa - p. page_285 34. 30: Skin of Color - p. page_290 35. 31: Hidradenitis Suppurativa in Women - p. page_296 36. Section 5: Combined Approach - p. page_306 37. 32: Building a Multidisciplinary Hidradenitis Suppurativa Clinic - p. page_309 38. 33: Support Groups in Hidradenitis Suppurativa—Building a Community - p. page_314 39. Section 6: On the Horizon - p. page_318 40. 34: Pipeline Therapeutics - p. page_321 41. 35: The Future - p. page_332 42. Index - p. page_337
Despite being a relatively straightforward clinical diagnosis, recognition of hidradenitis suppurativa (HS) is highly variable, and clinical management is challenging and complex. Written by the world’s leading experts in HS, A Comprehensive Guide to Hidradenitis Suppurativa brings together up-to-date scientific evidence on the diagnosis, patho-mechanisms, comorbidities, and multi-faceted medical and surgical interventions for this debilitating condition—in one convenient reference.
Covers every aspect of this complex skin disorder: etiology, pathophysiology, epidemiology, medical, alternative therapies, a range of surgical options, laser treatments, and comorbidities.
Discusses specific patient populations such as children, women of childbearing potential, and pregnant and breastfeeding women. Because HS has higher prevalence in people of skin of color, this patient population is well-documented in the text.
Offers insights into multi-disciplinary care, patient support and education, patients at risk for rapid disease progression, and clinical and translational research.
Features procedural videos covering laser therapies, de-roofing procedures, excisions and closure techniques, cryoinsufflation techniques, and special wound care material selection and techniques.
Includes recent FDA-approved drugs as well as those drugs and therapies that show future promise.
Identifies evidence gaps that provide a springboard to the future innovations in HS care to come.
Edited and authored by global experts who have co-authored 2019 U.S. and Canadian guidelines on hidradenitis suppurativa.
1. Section 1: Introduction to Hidradenitis Suppurativa - p. page_xxi 2. 1: Historical Perspective on Hidradenitis Suppurativa - p. page_3 3. 2: Hidradenitis Suppurativa Epidemiology - p. page_10 4. 3: Clinical Manifestation and Phenotypes of Hidradenitis Suppurativa - p. page_18 5. 4: Hidradenitis Suppurativa Differential Diagnosis and Mimickers - p. page_27 6. 5: Histopathology of the Pilosebaceous Unit and Interstitium of Hidradenitis Suppurativa - p. page_37 7. 6: Imaging Techniques in Hidradenitis Suppurativa and Comorbidities - p. page_45 8. 7: Clinical Evaluation - p. page_62 9. 8: Comorbidities and Systemic Associations - p. page_69 10. 9: Disease Complications - p. page_77 11. Section 2: Pathogenesis - p. page_86 12. 10: Follicular Occlusion and Inflammation - p. page_89 13. 11: Microbiota Perturbations in Hidradenitis Suppurativa - p. page_100 14. 12: Genetics and Epigenetics of Hidradenitis Suppurativa - p. page_105 15. Section 3: Clinician’s Corner - p. page_116 16. 13: Disease Evaluation and Outcome Measures - p. page_121 17. 14: Overview and Comparison of Hidradenitis Suppurativa Management Guidelines - p. page_130 18. 15: Topical Therapeutics - p. page_145 19. 16: Systemic Antibiotics in Hidradenitis Suppurativa - p. page_155 20. 17: Non-Antibiotic and Non-Biologic Systemic Therapeutics - p. page_167 21. 18: Targeted Therapeutics: Biologics, Small Molecules - p. page_182 22. 19: Pain and Itch Control - p. page_191 23. 20: Dressings and Wound Care Supplies for Hidradenitis Suppurativa - p. page_201 24. 21: Quality of Life - p. page_208 25. 22: Office-Based Non-Excision Procedures - p. page_215 26. 23: Operative Techniques for Hidradenitis Suppurativa - p. page_226 27. 24: Office-Based Excision for Hidradenitis Suppurativa: A Surgeon’s Decades-Long Experience - p. page_233 28. 25: Laser and Light Treatments for Hidradenitis Suppurativa - p. page_248 29. 26: Hidradenitis Suppurativa—Other Procedural Treatments - p. page_254 30. 27: Lifestyle Modifications - p. page_264 31. 28: Complementary and Alternative Medicine - p. page_273 32. Section 4: Special Populations - p. page_282 33. 29: Pediatric Hidradenitis Suppurativa - p. page_285 34. 30: Skin of Color - p. page_290 35. 31: Hidradenitis Suppurativa in Women - p. page_296 36. Section 5: Combined Approach - p. page_306 37. 32: Building a Multidisciplinary Hidradenitis Suppurativa Clinic - p. page_309 38. 33: Support Groups in Hidradenitis Suppurativa—Building a Community - p. page_314 39. Section 6: On the Horizon - p. page_318 40. 34: Pipeline Therapeutics - p. page_321 41. 35: The Future - p. page_332 42. Index - p. page_337
