Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases.
The book’s final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids.
1. Advancement of Phenolic Acids in Drug Discovery - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. List of Illustrations - p. Page viii 9. List of Tables - p. Page ix 10. Chapter 1 : Phenolic acids: a brief overview* - p. Page ix 11. Chapter 2 : Sources and extraction methods of phenolic acids - p. Page 9 12. Chapter 3 : Role of phenolic acids in plant system - p. Page 38 13. Chapter 4A : Antioxidant methods, in vitro and in vivo studies of phenolic acids - p. Page 54 14. Chapter 4B : Phenolic acids as potent antioxidant agents - p. Page 133 15. Chapter 5 : Progressive approach of phenolic acids toward the advancement of antimicrobial drugs - p. Page 165 16. Chapter 6 : Promising role of phenolic acids as antimalarial and antiviral drugs - p. Page 200 17. Chapter 7 : Development of phenolic acids-based system as anticancer drugs - p. Page 247 18. Chapter 8 : Utility of phenolic acids in neurological disorders - p. Page 280 19. Chapter 9 : Role of Aronia’s phenolic acids in the treatment of diabetes mellitus - p. Page 331 20. Chapter 10 : Role of phenolic acids in treatment and prevention of cardiovascular diseases - p. Page 361 21. Chapter 11 : Development of phenolic acid–based nanoparticles and nanomedicines - p. Page 385 22. Chapter 12 : Valorization of phenolic compounds delivery through lactic acid fermentation of fruit and vegetable juices: innovations, challenges, and gaps - p. Page 424 23. Chapter 13 : Development of metal–phenolic acid network for biomedical usages - p. Page 455 24. Chapter 14 : Grand challenges and opportunities for phenolic acids - p. Page 478 25. Index - p. Page 493
Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases.
The book’s final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids.
1. Advancement of Phenolic Acids in Drug Discovery - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. List of Illustrations - p. Page viii 9. List of Tables - p. Page ix 10. Chapter 1 : Phenolic acids: a brief overview* - p. Page ix 11. Chapter 2 : Sources and extraction methods of phenolic acids - p. Page 9 12. Chapter 3 : Role of phenolic acids in plant system - p. Page 38 13. Chapter 4A : Antioxidant methods, in vitro and in vivo studies of phenolic acids - p. Page 54 14. Chapter 4B : Phenolic acids as potent antioxidant agents - p. Page 133 15. Chapter 5 : Progressive approach of phenolic acids toward the advancement of antimicrobial drugs - p. Page 165 16. Chapter 6 : Promising role of phenolic acids as antimalarial and antiviral drugs - p. Page 200 17. Chapter 7 : Development of phenolic acids-based system as anticancer drugs - p. Page 247 18. Chapter 8 : Utility of phenolic acids in neurological disorders - p. Page 280 19. Chapter 9 : Role of Aronia’s phenolic acids in the treatment of diabetes mellitus - p. Page 331 20. Chapter 10 : Role of phenolic acids in treatment and prevention of cardiovascular diseases - p. Page 361 21. Chapter 11 : Development of phenolic acid–based nanoparticles and nanomedicines - p. Page 385 22. Chapter 12 : Valorization of phenolic compounds delivery through lactic acid fermentation of fruit and vegetable juices: innovations, challenges, and gaps - p. Page 424 23. Chapter 13 : Development of metal–phenolic acid network for biomedical usages - p. Page 455 24. Chapter 14 : Grand challenges and opportunities for phenolic acids - p. Page 478 25. Index - p. Page 493
