Advances in Clinical Chemistry, Volume 121, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists.
1. 1 Introduction - p. 2 2. 2 Blood-brain barrier: overview - p. 4 3. 3 Blood-brain barrier in aging - p. 11 4. 4 Biomarkers: a brief introduction - p. 16 5. 5 Biomarkers for blood-brain barrier integrity - p. 19 6. 6 Cellular biomarkers of the BBB - p. 23 7. 7 Protein markers of the BBB - p. 29 8. 8 Imaging Markers of the BBB - p. 35 9. 9 Blood-brain barrier markers in neurodegenerative disease - p. 39 10. 10 Blood-brain barrier biomarkers for cerebrovascular diseases - p. 45 11. 11 Blood-brain barrier biomarkers for neuroinflammatory diseases - p. 48 12. 12 Blood-brain barrier biomarkers in neuropsychiatric conditions - p. 51 13. 13 Challenges in BBB biomarker research - p. 54 14. 14 Emerging trends in BBB biomarker research and future perspectives - p. 55 15. 15 Conclusions - p. 55 16. Acknowledgements - p. 56 17. References - p. 86 18. Chapter Two: suPAR in cardiovascular disease - p. 90 19. Chapter Three: Pleiotropic functions and clinical importance of circulating HDL-PON1 complex - p. 134 20. Chapter Four: Adipokines in pregnancy - p. 175 21. Abstract - p. 175 22. Abbreviations - p. 175 23. 1 Introduction - p. 176 24. 2 Characteristics of adipokines and their receptors - p. 187 25. 3 Plasma levels and placental expression of adipokines during pregnancy - p. 204 26. 4 Effect of adipokines on placenta function - p. 214 27. 5 Levels of adipokines in plasma and placental in pregnancy pathologies - p. 223 28. 6 Summary and future perspectives - p. 239 29. References - p. 270 30. Chapter Five: Proteostasis in neurodegenerative diseases - p. 273 31. Chapter Six: Mitochondria: A source of potential biomarkers for non-communicable diseases - p. 337 32. Index - p. 366
Advances in Clinical Chemistry, Volume 121, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists.
1. 1 Introduction - p. 2 2. 2 Blood-brain barrier: overview - p. 4 3. 3 Blood-brain barrier in aging - p. 11 4. 4 Biomarkers: a brief introduction - p. 16 5. 5 Biomarkers for blood-brain barrier integrity - p. 19 6. 6 Cellular biomarkers of the BBB - p. 23 7. 7 Protein markers of the BBB - p. 29 8. 8 Imaging Markers of the BBB - p. 35 9. 9 Blood-brain barrier markers in neurodegenerative disease - p. 39 10. 10 Blood-brain barrier biomarkers for cerebrovascular diseases - p. 45 11. 11 Blood-brain barrier biomarkers for neuroinflammatory diseases - p. 48 12. 12 Blood-brain barrier biomarkers in neuropsychiatric conditions - p. 51 13. 13 Challenges in BBB biomarker research - p. 54 14. 14 Emerging trends in BBB biomarker research and future perspectives - p. 55 15. 15 Conclusions - p. 55 16. Acknowledgements - p. 56 17. References - p. 86 18. Chapter Two: suPAR in cardiovascular disease - p. 90 19. Chapter Three: Pleiotropic functions and clinical importance of circulating HDL-PON1 complex - p. 134 20. Chapter Four: Adipokines in pregnancy - p. 175 21. Abstract - p. 175 22. Abbreviations - p. 175 23. 1 Introduction - p. 176 24. 2 Characteristics of adipokines and their receptors - p. 187 25. 3 Plasma levels and placental expression of adipokines during pregnancy - p. 204 26. 4 Effect of adipokines on placenta function - p. 214 27. 5 Levels of adipokines in plasma and placental in pregnancy pathologies - p. 223 28. 6 Summary and future perspectives - p. 239 29. References - p. 270 30. Chapter Five: Proteostasis in neurodegenerative diseases - p. 273 31. Chapter Six: Mitochondria: A source of potential biomarkers for non-communicable diseases - p. 337 32. Index - p. 366
