Advances in Genetics, Volume 108 provides the latest information on genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, with this new release including chapters on Clinical applications of cancer genetics and genomics, Epigenetic mutations in childhood tumors- the paradigm of Wilms tumor, Preventive population genomics-the model of BRCA related cancers, Recent advances of PARP inhibitors in medical oncology, Role of single cell and liquid biopsy in cancer research and clinical applications.
Other chapters cover Recent advances and clinical utility of prostate cancer genomics, Recent advances in lung cancer genomics- applications in targeted therapy, and more.
1. 1 Introduction - p. 202 2. 2 Oncogene addiction - p. 203 3. 3 One disease model to molecular classification - p. 204 4. 4 Ethnic variations in genomic profile - p. 207 5. 5 Intra-tumoral heterogeneity - p. 208 6. 6 Clinical implications of genomic understanding of lung cancer - p. 208 7. 7 Biomarker testing in lung cancer - p. 209 8. 8 Methods of biomarker testing - p. 210 9. 9 Therapeutic landscape of genomics directed treatments in NSCLC - p. 222 10. 10 Immunotherapy and genomics - p. 249 11. 11 Small cell lung cancer - p. 248 12. 12 Conclusion - p. 250 13. References - p. 252 14. Chapter Six: Nutrigenetics and nutrigenomics—A personalized approach to nutrition - p. 297 15. Chapter Seven: Next-generation microbial drugs developed from microbiome's natural products - p. 356
Advances in Genetics, Volume 108 provides the latest information on genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, with this new release including chapters on Clinical applications of cancer genetics and genomics, Epigenetic mutations in childhood tumors- the paradigm of Wilms tumor, Preventive population genomics-the model of BRCA related cancers, Recent advances of PARP inhibitors in medical oncology, Role of single cell and liquid biopsy in cancer research and clinical applications.
Other chapters cover Recent advances and clinical utility of prostate cancer genomics, Recent advances in lung cancer genomics- applications in targeted therapy, and more.
1. 1 Introduction - p. 202 2. 2 Oncogene addiction - p. 203 3. 3 One disease model to molecular classification - p. 204 4. 4 Ethnic variations in genomic profile - p. 207 5. 5 Intra-tumoral heterogeneity - p. 208 6. 6 Clinical implications of genomic understanding of lung cancer - p. 208 7. 7 Biomarker testing in lung cancer - p. 209 8. 8 Methods of biomarker testing - p. 210 9. 9 Therapeutic landscape of genomics directed treatments in NSCLC - p. 222 10. 10 Immunotherapy and genomics - p. 249 11. 11 Small cell lung cancer - p. 248 12. 12 Conclusion - p. 250 13. References - p. 252 14. Chapter Six: Nutrigenetics and nutrigenomics—A personalized approach to nutrition - p. 297 15. Chapter Seven: Next-generation microbial drugs developed from microbiome's natural products - p. 356
