Advances in Tablet Manufacturing Technologies consolidates cutting-edge information on the latest technologies in tablet design and manufacturing, addressing the pressing need for innovation in an increasingly complex global market. The book is structured to provide a thorough understanding of tablet technology, beginning with foundational concepts and progressing through specialized topics. Key sections explore the historical context of tablet development, the significance of pharmaceutical excipients, preformulation aspects, and the physics of tablet compression. Subsequent chapters explore advanced topics, including coated tablets, modified-release formulations, organ-specific tablets, and state-of-the-art innovations like 3D printed tablets.
Each chapter is enriched with practical examples and case studies, ensuring that readers can apply theoretical knowledge to real-world scenarios. With contributions from a diverse group of national and international experts, this book is an invaluable asset for scientists in academia and industry alike. It elucidates preformulation parameters, outlines regulatory frameworks, and discusses recent advances in excipient technology and in-process testing equipment.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xvii 7. About the editors - p. xxi 8. Preface - p. xxiii 9. Section I: Basic fundamentals of tablet technology - p. S1 10. Chapter 1. Concepts of tablet technology - p. 3 11. Chapter 2. Functional pharmaceutical ingredients and tablet manufacturing excipients: regulatory standards with safety guidelines - p. 21 12. Chapter 3. Preformulation aspects for tablet processing - p. 67 13. Chapter 4. Physics of tablet compression - p. 87 14. Chapter 5. Global ‘state of the art’ practices in tablet manufacturing and processing: production methodologies with regulatory aspects - p. 123 15. Chapter 6. Global quality control testing and regulatory standards for tablet dosage forms - p. 181 16. Chapter 7. Standard in vitro dissolution testing criteria and technology for solid dosage forms - p. 197 17. Chapter 8. In vitro–in silico applications for tablet dosage forms - p. 229 18. Chapter 9. Life cycle assessment with stability and environmental impact of tablets from manufacturing process to post-marketing phase - p. 257 19. Section II: Novel renditions in tablet technologies for commercial scalable design - p. S291 20. Chapter 10. Coated tablets technologies - p. 293 21. Chapter 11. Modified-release tablet dosage forms - p. 317 22. Chapter 12. Tablets For oral cavity and upper gastrointestinal tract - p. 343 23. Chapter 13. Gastrointestinal-specific tablet dosage forms - p. 357 24. Chapter 14. Organ-specific mucoadhesive tablet systems - p. 377 25. Chapter 15. Tablets for insertion into body cavities - p. 411 26. Chapter 16. Oral disintegrating tablet dosage forms - p. 447 27. Chapter 17. Pelletized tablet dosage forms - p. 481 28. Chapter 18. Novel tablet technologies - p. 513 29. Chapter 19. Critical aspects and renditions in tablet labeling and packaging technology - p. 553 30. Chapter 20. 3D printed tablets - p. 577 31. Index - p. 611
Advances in Tablet Manufacturing Technologies consolidates cutting-edge information on the latest technologies in tablet design and manufacturing, addressing the pressing need for innovation in an increasingly complex global market. The book is structured to provide a thorough understanding of tablet technology, beginning with foundational concepts and progressing through specialized topics. Key sections explore the historical context of tablet development, the significance of pharmaceutical excipients, preformulation aspects, and the physics of tablet compression. Subsequent chapters explore advanced topics, including coated tablets, modified-release formulations, organ-specific tablets, and state-of-the-art innovations like 3D printed tablets.
Each chapter is enriched with practical examples and case studies, ensuring that readers can apply theoretical knowledge to real-world scenarios. With contributions from a diverse group of national and international experts, this book is an invaluable asset for scientists in academia and industry alike. It elucidates preformulation parameters, outlines regulatory frameworks, and discusses recent advances in excipient technology and in-process testing equipment.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xvii 7. About the editors - p. xxi 8. Preface - p. xxiii 9. Section I: Basic fundamentals of tablet technology - p. S1 10. Chapter 1. Concepts of tablet technology - p. 3 11. Chapter 2. Functional pharmaceutical ingredients and tablet manufacturing excipients: regulatory standards with safety guidelines - p. 21 12. Chapter 3. Preformulation aspects for tablet processing - p. 67 13. Chapter 4. Physics of tablet compression - p. 87 14. Chapter 5. Global ‘state of the art’ practices in tablet manufacturing and processing: production methodologies with regulatory aspects - p. 123 15. Chapter 6. Global quality control testing and regulatory standards for tablet dosage forms - p. 181 16. Chapter 7. Standard in vitro dissolution testing criteria and technology for solid dosage forms - p. 197 17. Chapter 8. In vitro–in silico applications for tablet dosage forms - p. 229 18. Chapter 9. Life cycle assessment with stability and environmental impact of tablets from manufacturing process to post-marketing phase - p. 257 19. Section II: Novel renditions in tablet technologies for commercial scalable design - p. S291 20. Chapter 10. Coated tablets technologies - p. 293 21. Chapter 11. Modified-release tablet dosage forms - p. 317 22. Chapter 12. Tablets For oral cavity and upper gastrointestinal tract - p. 343 23. Chapter 13. Gastrointestinal-specific tablet dosage forms - p. 357 24. Chapter 14. Organ-specific mucoadhesive tablet systems - p. 377 25. Chapter 15. Tablets for insertion into body cavities - p. 411 26. Chapter 16. Oral disintegrating tablet dosage forms - p. 447 27. Chapter 17. Pelletized tablet dosage forms - p. 481 28. Chapter 18. Novel tablet technologies - p. 513 29. Chapter 19. Critical aspects and renditions in tablet labeling and packaging technology - p. 553 30. Chapter 20. 3D printed tablets - p. 577 31. Index - p. 611
