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This issue of Anesthesiology Clinics, guest edited by Drs. Ranjit Deshpande and Stanley Rosenbaum, is focused on Anesthesia at the Edge of Life. This issue is one of four each year selected by the series Consulting Editor, Dr. Lee Fleisher. Articles in this issue include but are not limited to: Anesthesia for major surgery in the neonate; Anesthesia for the patient on mechanical circulatory support; Anesthesia for the patient with severe liver failure; Anesthesia for the patient on renal replacement therapy; Anesthesia for neurosurgical emergencies; Anesthesia for obstetrical disasters; Anesthesia for the patient in septic shock; Anesthesia for a patient with extensive trauma; Anesthesia for endocrine emergencies; Anesthetic management in malignant hyperthermia; Anesthesia for electroconvulsive therapy; Anesthesia for the morbidly obese patient; Anesthesia for the frail geriatric patient; Emergency anesthesia in resource-limited areas; and Organ donation and ethics in anesthesiology.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xii 7. Foreword - p. xiii 8. Preface - p. xv 9. Anesthesia for Major Surgery in the Neonate - p. 1 10. Anesthesia at the Edge of Life: Mechanical Circulatory Support - p. 19 11. Anesthesia for the Patient with Severe Liver Failure - p. 35 12. Anesthetic Considerations for Patients on Renal Replacement Therapy - p. 51 13. Anesthesia for Neurosurgical Emergencies - p. 67 14. Anesthesia for Obstetric Disasters - p. 85 15. Perioperative Management of Patients with Sepsis and Septic Shock, Part I: Systematic Approach - p. 107 16. Perioperative Management of Patients with Sepsis and Septic Shock, Part II: Ultrasound Support for Resuscitation - p. 123 17. Anesthesia for Patients with Extensive Trauma - p. 135 18. Anesthesia for Endocrine Emergencies - p. 149 19. Malignant Hyperthermia Update - p. 165 20. Anesthesia for Electroconvulsive Therapy - p. 183 21. Anesthesia for the Morbidly Obese Patient - p. 197 22. Emergency Anesthesia in Resource-Limited Areas - p. 213 23. Ethical Issues in Organ Transplantation at End of Life: Defining Death - p. 231

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This issue of Anesthesiology Clinics, guest edited by Drs. Ranjit Deshpande and Stanley Rosenbaum, is focused on Anesthesia at the Edge of Life. This issue is one of four each year selected by the series Consulting Editor, Dr. Lee Fleisher. Articles in this issue include but are not limited to: Anesthesia for major surgery in the neonate; Anesthesia for the patient on mechanical circulatory support; Anesthesia for the patient with severe liver failure; Anesthesia for the patient on renal replacement therapy; Anesthesia for neurosurgical emergencies; Anesthesia for obstetrical disasters; Anesthesia for the patient in septic shock; Anesthesia for a patient with extensive trauma; Anesthesia for endocrine emergencies; Anesthetic management in malignant hyperthermia; Anesthesia for electroconvulsive therapy; Anesthesia for the morbidly obese patient; Anesthesia for the frail geriatric patient; Emergency anesthesia in resource-limited areas; and Organ donation and ethics in anesthesiology.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xii 7. Foreword - p. xiii 8. Preface - p. xv 9. Anesthesia for Major Surgery in the Neonate - p. 1 10. Anesthesia at the Edge of Life: Mechanical Circulatory Support - p. 19 11. Anesthesia for the Patient with Severe Liver Failure - p. 35 12. Anesthetic Considerations for Patients on Renal Replacement Therapy - p. 51 13. Anesthesia for Neurosurgical Emergencies - p. 67 14. Anesthesia for Obstetric Disasters - p. 85 15. Perioperative Management of Patients with Sepsis and Septic Shock, Part I: Systematic Approach - p. 107 16. Perioperative Management of Patients with Sepsis and Septic Shock, Part II: Ultrasound Support for Resuscitation - p. 123 17. Anesthesia for Patients with Extensive Trauma - p. 135 18. Anesthesia for Endocrine Emergencies - p. 149 19. Malignant Hyperthermia Update - p. 165 20. Anesthesia for Electroconvulsive Therapy - p. 183 21. Anesthesia for the Morbidly Obese Patient - p. 197 22. Emergency Anesthesia in Resource-Limited Areas - p. 213 23. Ethical Issues in Organ Transplantation at End of Life: Defining Death - p. 231

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