Animal Models of Disease, Part B, Volume 188 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Using C. Elegans as a model for Neurodegenerative disease: Methodology and Evaluation, Modelo Animal de Esclerosis Multiple: Encefalomielitis Autoimmune Experimental (EAE, New mouse model to study aneurysm development, Spinal Nerve Ligation: An Experimental Neuropathic Pain Model in Rats and Mice, Identifying therapeutic compounds for Autosomal Dominant Optic Atrophy (ADOA) through screening in the nematode C. elegans, Eµ-TCL1 adoptive transfer mouse model of chronic lymphocytic leukemia, and much more.
Other chapters cover Purification and characterization of kidney-infiltrating leukocytes in a mouse model of lupus nephritis, Differences in intratumor innate lymphoid cell composition between orthotopic and spontaneous pancreatic mouse models, Assessing motor development and function in mouse models of neurodevelopmental disorders, Analysis of Gut Microbiota profile targeted to multi hypervariable regions of 16S rRNA in hypertensive heart failure rat model, and more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Series Page - p. iii 5. Copyright - p. iii 6. Contributors - p. iii 7. Animal models of disease: Achievements and challenges - p. xv 8. Chapter One: Using C. elegans as a model for neurodegenerative diseases: Methodology and evaluation - p. 1 9. Chapter Two: Animal model of multiple sclerosis: Experimental autoimmune encephalomyelitis - p. 35 10. Chapter Three: A new procedure to induce aortic aneurysms in mice - p. 61 11. Chapter Four: Spinal nerve ligation: An experimental model to study neuropathic pain in rats and mice - p. 73 12. Chapter Five: Identifying therapeutic compounds for autosomal dominant optic atrophy (ADOA) through screening in the nematode C. elegans - p. 89 13. Chapter Six: Eμ-TCL1 adoptive transfer mouse model of chronic lymphocytic leukemia - p. 109 14. Chapter Seven: Purification and analysis of kidney-infiltrating leukocytes in a mouse model of lupus nephritis - p. 131 15. Chapter Eight: Differences in intratumor innate lymphoid cell composition between orthotopic and spontaneous pancreatic mouse models - p. 153 16. Chapter Nine: Assessing motor development and function in mouse models of neurodevelopmental disorders - p. 171 17. Chapter Ten: Analysis of the gut microbiota profile targeted to multiple hypervariable regions of 16S rRNA in a hypertensive heart failure rat model - p. 183 18. Chapter Eleven: Animal models of neglected parasitic diseases: In vivo multimodal imaging of experimental trypanosomatid infections - p. 205 19. Chapter Twelve: Intracranial graft of bioresorbable polymer scaffolds loaded with human Dental Pulp Stem Cells in stab wound murine injury model - p. 237
Animal Models of Disease, Part B, Volume 188 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Using C. Elegans as a model for Neurodegenerative disease: Methodology and Evaluation, Modelo Animal de Esclerosis Multiple: Encefalomielitis Autoimmune Experimental (EAE, New mouse model to study aneurysm development, Spinal Nerve Ligation: An Experimental Neuropathic Pain Model in Rats and Mice, Identifying therapeutic compounds for Autosomal Dominant Optic Atrophy (ADOA) through screening in the nematode C. elegans, Eµ-TCL1 adoptive transfer mouse model of chronic lymphocytic leukemia, and much more.
Other chapters cover Purification and characterization of kidney-infiltrating leukocytes in a mouse model of lupus nephritis, Differences in intratumor innate lymphoid cell composition between orthotopic and spontaneous pancreatic mouse models, Assessing motor development and function in mouse models of neurodevelopmental disorders, Analysis of Gut Microbiota profile targeted to multi hypervariable regions of 16S rRNA in hypertensive heart failure rat model, and more.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Series Page - p. iii 5. Copyright - p. iii 6. Contributors - p. iii 7. Animal models of disease: Achievements and challenges - p. xv 8. Chapter One: Using C. elegans as a model for neurodegenerative diseases: Methodology and evaluation - p. 1 9. Chapter Two: Animal model of multiple sclerosis: Experimental autoimmune encephalomyelitis - p. 35 10. Chapter Three: A new procedure to induce aortic aneurysms in mice - p. 61 11. Chapter Four: Spinal nerve ligation: An experimental model to study neuropathic pain in rats and mice - p. 73 12. Chapter Five: Identifying therapeutic compounds for autosomal dominant optic atrophy (ADOA) through screening in the nematode C. elegans - p. 89 13. Chapter Six: Eμ-TCL1 adoptive transfer mouse model of chronic lymphocytic leukemia - p. 109 14. Chapter Seven: Purification and analysis of kidney-infiltrating leukocytes in a mouse model of lupus nephritis - p. 131 15. Chapter Eight: Differences in intratumor innate lymphoid cell composition between orthotopic and spontaneous pancreatic mouse models - p. 153 16. Chapter Nine: Assessing motor development and function in mouse models of neurodevelopmental disorders - p. 171 17. Chapter Ten: Analysis of the gut microbiota profile targeted to multiple hypervariable regions of 16S rRNA in a hypertensive heart failure rat model - p. 183 18. Chapter Eleven: Animal models of neglected parasitic diseases: In vivo multimodal imaging of experimental trypanosomatid infections - p. 205 19. Chapter Twelve: Intracranial graft of bioresorbable polymer scaffolds loaded with human Dental Pulp Stem Cells in stab wound murine injury model - p. 237
