Antidiabetic Drug Discovery from Natural Products provides up-to-date and in-depth information, practical understanding, and guidance in a comprehensive, systematic and easy-to-understand manner to scientists, researchers, and graduate students on important and emerging biochemical topics related to current antidiabetic drug discovery research. This book analyzes and studies natural active substances and their medicinal chemistry in preventing and treating diabetes and its complications. It covers a wide range of critical issues to assist chemists in the discovery and development of safer, more affordable treatments, from identifying promising leads from medicinal plants to the extraction and synthesis of bioactive compounds.
Following an introduction to bioactive chemical compounds from plants with antidiabetic effects, the book describes the discovery and extraction of antidiabetic drugs and antioxidants from natural sources. It also examines antidiabetic plants before delving deeper into the chemistry behind major medicinal substances and their derivatives like Mangiferin and Resveratrol, discussing both current and prospective uses.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Copyright - p. iv 5. List of contributors - p. xi 6. Section 1: Putative antidiabetic drugs - p. 1 7. 1. Natural products in antidiabetic drug discovery: a historical perspective - p. 3 8. 2. Natural products in antidiabetic drug discovery: advances and opportunities - p. 39 9. Section 2: Plant bioactives and their antidiabetic potential - p. 51 10. 3. Antidiabetic flavonoids from plant sources - p. 53 11. 4. Natural terpenoids: exploring their antidiabetic potential and mechanism of action - p. 109 12. 5. Antidiabetic potential of plant alkaloids - p. 153 13. 6. Antidiabetic carbohydrates from natural sources - p. 189 14. 7. Antidiabetic potential of glycosides - p. 225 15. 8. Potentials of tannins in diabetes: an update - p. 263 16. 9. Biological macromolecules as antidiabetic agents - p. 281 17. 10. Antidiabetic drugs from fungi - p. 327 18. 11. Exploring marine metabolites for diabetes management: new horizons in diabetes treatment - p. 369 19. Section 3: Pharmacological mechanism - p. 417 20. 12. Exploring in vitro techniques as new frontiers in antidiabetic drug screening - p. 419 21. 13. Animal models used in screening antidiabetic drugs from natural sources - p. 457 22. 14. Molecular mechanisms of secondary metabolites as antidiabetic agents - p. 477 23. 15. Network pharmacology approach for antidiabetic drugs from natural sources - p. 505 24. Section 4: Natural antidiabetics: nature to clinic and market - p. 529 25. 16. Recent advances in natural antidiabetics - p. 531 26. 17. Antidiabetic drugs and marketed formulations from natural products - p. 569 27. 18. Antidiabetic drugs: patent case studies - p. 615 28. 19. Natural antidiabetic herbs and interactions - p. 643 29. Index - p. 681
Antidiabetic Drug Discovery from Natural Products provides up-to-date and in-depth information, practical understanding, and guidance in a comprehensive, systematic and easy-to-understand manner to scientists, researchers, and graduate students on important and emerging biochemical topics related to current antidiabetic drug discovery research. This book analyzes and studies natural active substances and their medicinal chemistry in preventing and treating diabetes and its complications. It covers a wide range of critical issues to assist chemists in the discovery and development of safer, more affordable treatments, from identifying promising leads from medicinal plants to the extraction and synthesis of bioactive compounds.
Following an introduction to bioactive chemical compounds from plants with antidiabetic effects, the book describes the discovery and extraction of antidiabetic drugs and antioxidants from natural sources. It also examines antidiabetic plants before delving deeper into the chemistry behind major medicinal substances and their derivatives like Mangiferin and Resveratrol, discussing both current and prospective uses.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Copyright - p. iv 5. List of contributors - p. xi 6. Section 1: Putative antidiabetic drugs - p. 1 7. 1. Natural products in antidiabetic drug discovery: a historical perspective - p. 3 8. 2. Natural products in antidiabetic drug discovery: advances and opportunities - p. 39 9. Section 2: Plant bioactives and their antidiabetic potential - p. 51 10. 3. Antidiabetic flavonoids from plant sources - p. 53 11. 4. Natural terpenoids: exploring their antidiabetic potential and mechanism of action - p. 109 12. 5. Antidiabetic potential of plant alkaloids - p. 153 13. 6. Antidiabetic carbohydrates from natural sources - p. 189 14. 7. Antidiabetic potential of glycosides - p. 225 15. 8. Potentials of tannins in diabetes: an update - p. 263 16. 9. Biological macromolecules as antidiabetic agents - p. 281 17. 10. Antidiabetic drugs from fungi - p. 327 18. 11. Exploring marine metabolites for diabetes management: new horizons in diabetes treatment - p. 369 19. Section 3: Pharmacological mechanism - p. 417 20. 12. Exploring in vitro techniques as new frontiers in antidiabetic drug screening - p. 419 21. 13. Animal models used in screening antidiabetic drugs from natural sources - p. 457 22. 14. Molecular mechanisms of secondary metabolites as antidiabetic agents - p. 477 23. 15. Network pharmacology approach for antidiabetic drugs from natural sources - p. 505 24. Section 4: Natural antidiabetics: nature to clinic and market - p. 529 25. 16. Recent advances in natural antidiabetics - p. 531 26. 17. Antidiabetic drugs and marketed formulations from natural products - p. 569 27. 18. Antidiabetic drugs: patent case studies - p. 615 28. 19. Natural antidiabetic herbs and interactions - p. 643 29. Index - p. 681
