Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease.
In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Contributors - p. xv 8. Foreword - p. xvii 9. Preface - p. xix 10. Chapter 1. Apolipoprotein E (ApoE): Structural insights, functionality, and genetic variability - p. 1 11. Chapter 2. Apolipoprotein E and cardiovascular pathophysiology: A comprehensive exploration - p. 13 12. Chapter 3. Apolipoprotein E in Alzheimer’s disease: Genetic predisposition and mechanistic implications - p. 21 13. Chapter 4. Apolipoprotein E and neurological disorders beyond Alzheimer's disease - p. 37 14. Chapter 5. Apolipoprotein E's impact on metabolic syndrome: A systematic analysis - p. 49 15. Chapter 6. Apolipoprotein E and liver health: Implications in lipid metabolism and diseases - p. 61 16. Chapter 7. Apolipoprotein E and its role in cancer: Insight into carcinogenic associations - p. 73 17. Chapter 8. Apolipoprotein E's immune mediation: Implications in inflammatory disorders - p. 89 18. Chapter 9. Apoprotein E: Structural insights functionality and genetic variability - p. 105 19. Chapter 10. Apolipoprotein E as a therapeutic target in Alzheimer's disease: A review of basic research and clinical evidence - p. 119 20. Chapter 11. Apolipoprotein E and infectious diseases: A framework for therapeutic developments - p. 141 21. Chapter 12. Apolipoprotein E in drug delivery systems—targeted pharmacotherapeutics - p. 155 22. Chapter 13. Apolipoprotein E and precision medicine: Individualized disease management approaches - p. 189 23. Chapter 14. Apolipoprotein E and autoimmune disorders: Therapeutic frontier - p. 217 24. Chapter 15. Apolipoprotein E in aging and resilience: A genotype-based view of longevity - p. 233 25. Chapter 16. ApoE as a biomarker and therapeutic target in atherosclerotic cardiovascular disease - p. 249 26. Chapter 17. The diagnostic and therapeutic significance of apolipoprotein E in personalized medicine - p. 279 27. Index - p. 303
Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease.
In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Contributors - p. xv 8. Foreword - p. xvii 9. Preface - p. xix 10. Chapter 1. Apolipoprotein E (ApoE): Structural insights, functionality, and genetic variability - p. 1 11. Chapter 2. Apolipoprotein E and cardiovascular pathophysiology: A comprehensive exploration - p. 13 12. Chapter 3. Apolipoprotein E in Alzheimer’s disease: Genetic predisposition and mechanistic implications - p. 21 13. Chapter 4. Apolipoprotein E and neurological disorders beyond Alzheimer's disease - p. 37 14. Chapter 5. Apolipoprotein E's impact on metabolic syndrome: A systematic analysis - p. 49 15. Chapter 6. Apolipoprotein E and liver health: Implications in lipid metabolism and diseases - p. 61 16. Chapter 7. Apolipoprotein E and its role in cancer: Insight into carcinogenic associations - p. 73 17. Chapter 8. Apolipoprotein E's immune mediation: Implications in inflammatory disorders - p. 89 18. Chapter 9. Apoprotein E: Structural insights functionality and genetic variability - p. 105 19. Chapter 10. Apolipoprotein E as a therapeutic target in Alzheimer's disease: A review of basic research and clinical evidence - p. 119 20. Chapter 11. Apolipoprotein E and infectious diseases: A framework for therapeutic developments - p. 141 21. Chapter 12. Apolipoprotein E in drug delivery systems—targeted pharmacotherapeutics - p. 155 22. Chapter 13. Apolipoprotein E and precision medicine: Individualized disease management approaches - p. 189 23. Chapter 14. Apolipoprotein E and autoimmune disorders: Therapeutic frontier - p. 217 24. Chapter 15. Apolipoprotein E in aging and resilience: A genotype-based view of longevity - p. 233 25. Chapter 16. ApoE as a biomarker and therapeutic target in atherosclerotic cardiovascular disease - p. 249 26. Chapter 17. The diagnostic and therapeutic significance of apolipoprotein E in personalized medicine - p. 279 27. Index - p. 303
