Apprentices to Genius: A tribute to Solomon H. Snyder, a volume in the Advances in Pharmacology series, presents a tribute to Dr. Solomon H. Snyder, highlighting chapters submitted from a broad range of his students. It covers many different areas of neuroscience and pharmacology, with this volume exploring how receptor binding and drug discovery, the emerging role of glutamate in the pathophysiology of mental illness, nitric oxide signaling in neurodegeneration and cell death, carboxypeptidase E and the identification of novel neuropeptides as potential therapeutic targets, the regulation of mitochondrial functions by TSPO, clozapine and its translational investigation, and more.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Preface - p. xix 7. Foreword - p. xxi 8. Chapter One: Multiple Pathways Mediate MicroRNA Degradation: Focus on the Translin/Trax RNase Complex - p. xxii 9. Chapter Two: Receptor Binding Assays and Drug Discovery - p. 20 10. Chapter Three: The Role of Serine Racemase in the Pathophysiology of Brain Disorders - p. 34 11. Chapter Four: Nitric Oxide Signaling in Neurodegeneration and Cell Death - p. 56 12. Chapter Five: Carboxypeptidase E and the Identification of Novel Neuropeptides as Potential Therapeutic Targets - p. 83 13. Chapter Six: Regulation of Mitochondrial, Cellular, and Organismal Functions by TSPO - p. 102 14. Chapter Seven: Unique Effects of Clozapine: A Pharmacological Perspective - p. 136 15. Chapter Eight: Imaging Translocator Protein as a Biomarker of Neuroinflammation in Dementia - p. 162 16. Chapter Nine: RNA-Based Fluorescent Biosensors for Detecting Metabolites in vitro and in Living Cells - p. 185 17. Chapter Ten: Phosphorylation of the Amino Terminus of the Dopamine Transporter: Regulatory Mechanisms and Implications for Amphetamine Action - p. 203 18. Chapter Eleven: Anti-NMDA Receptor Encephalitis: Clinical Features and Basic Mechanisms - p. 234 19. Chapter Twelve: Mu Opioid Pharmacology: 40 Years to the Promised Land - p. 260 20. Chapter Thirteen: Synaptotoxic Signaling by Amyloid Beta Oligomers in Alzheimer's Disease Through Prion Protein and mGluR5 - p. 291 21. Chapter Fourteen: The Neurobiology of d-Serine Signaling - p. 323
Apprentices to Genius: A tribute to Solomon H. Snyder, a volume in the Advances in Pharmacology series, presents a tribute to Dr. Solomon H. Snyder, highlighting chapters submitted from a broad range of his students. It covers many different areas of neuroscience and pharmacology, with this volume exploring how receptor binding and drug discovery, the emerging role of glutamate in the pathophysiology of mental illness, nitric oxide signaling in neurodegeneration and cell death, carboxypeptidase E and the identification of novel neuropeptides as potential therapeutic targets, the regulation of mitochondrial functions by TSPO, clozapine and its translational investigation, and more.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xi 6. Preface - p. xix 7. Foreword - p. xxi 8. Chapter One: Multiple Pathways Mediate MicroRNA Degradation: Focus on the Translin/Trax RNase Complex - p. xxii 9. Chapter Two: Receptor Binding Assays and Drug Discovery - p. 20 10. Chapter Three: The Role of Serine Racemase in the Pathophysiology of Brain Disorders - p. 34 11. Chapter Four: Nitric Oxide Signaling in Neurodegeneration and Cell Death - p. 56 12. Chapter Five: Carboxypeptidase E and the Identification of Novel Neuropeptides as Potential Therapeutic Targets - p. 83 13. Chapter Six: Regulation of Mitochondrial, Cellular, and Organismal Functions by TSPO - p. 102 14. Chapter Seven: Unique Effects of Clozapine: A Pharmacological Perspective - p. 136 15. Chapter Eight: Imaging Translocator Protein as a Biomarker of Neuroinflammation in Dementia - p. 162 16. Chapter Nine: RNA-Based Fluorescent Biosensors for Detecting Metabolites in vitro and in Living Cells - p. 185 17. Chapter Ten: Phosphorylation of the Amino Terminus of the Dopamine Transporter: Regulatory Mechanisms and Implications for Amphetamine Action - p. 203 18. Chapter Eleven: Anti-NMDA Receptor Encephalitis: Clinical Features and Basic Mechanisms - p. 234 19. Chapter Twelve: Mu Opioid Pharmacology: 40 Years to the Promised Land - p. 260 20. Chapter Thirteen: Synaptotoxic Signaling by Amyloid Beta Oligomers in Alzheimer's Disease Through Prion Protein and mGluR5 - p. 291 21. Chapter Fourteen: The Neurobiology of d-Serine Signaling - p. 323
