Intracranial arachnoid cysts are congenital malformations with a predilection for the middle cranial fossa and an estimated prevalence in the general population as high as 1.7%. The common assumption is that these cysts are incidental findings and the symptoms associated with them are not caused by the cyst and consequently, that surgical intervention will not benefit the patient. However, there is now a growing understanding reflected in the international literature among neurologists and neurosurgeons that arachnoid cysts do harm and that the patients’ complaints can be relieved by surgical treatment.
Arachnoid Cysts: Epidemiology, Biology, and Neuroimaging gives a broad and updated presentation of the condition, including epidemiology, etiology, biology (including genetics and molecular biology), and neuroimaging of same. This book is written for researchers, residents, and clinical practitioners in clinical neuroscience, neurology, neurosurgery, neuroradiology, and pediatrics.
1. Part I: Introduction - p. xvi 2. Chapter 1. Arachnoid Cysts—Historical Perspectives and Controversial Aspects - p. 3 3. Part II: Biological Aspects - p. 15 4. Chapter 2. Arachnoid Cysts—Intracranial Locations, Gender, and Sidedness - p. 19 5. Chapter 3. Molecular Biology and Genetics: Gene Expression, Twin Studies and Familial Occurrence, and Syndromes Associated With AC - p. 27 6. Chapter 4. Arachnoid Cysts in Glutaric Aciduria Type I (GA-I) - p. 39 7. Chapter 5. Ultrastructure of Arachnoid Cysts - p. 57 8. Chapter 6. Pathophysiology of Intracranial Arachnoid Cysts: Hypoperfusion of Adjacent Cortex - p. 67 9. Chapter 7. Biochemistry—Composition of and Possible Mechanisms for Production of Arachnoid Cyst Fluid - p. 75 10. Chapter 8. The “Valve Mechanism” - p. 85 11. Part III: Prevalence and Natural History of Arachnoid Cysts - p. 92 12. Chapter 9. The Prevalence of Intracranial Arachnoid Cysts - p. 95 13. Chapter 10. Classification and Location of Arachnoid Cysts - p. 101 14. Chapter 11. Growth and Disappearance of Arachnoid Cysts - p. 111 15. Chapter 12. Arachnoid Cysts and Subdural and Intracystic Hematomas - p. 125 16. Chapter 13. Hydrocephalus Associated With Arachnoid Cysts - p. 139 17. Part IV: Neuroimaging - p. 166 18. Chapter 14. Radiological Workup, CT, MRI - p. 173 19. Chapter 15. Arachnoid Cyst—Prenatal Detection, Management, and Perinatal Outcome - p. 187 20. Chapter 16. SPECT Studies in Patients With Arachnoid Cysts - p. 199 21. Index - p. 215
Intracranial arachnoid cysts are congenital malformations with a predilection for the middle cranial fossa and an estimated prevalence in the general population as high as 1.7%. The common assumption is that these cysts are incidental findings and the symptoms associated with them are not caused by the cyst and consequently, that surgical intervention will not benefit the patient. However, there is now a growing understanding reflected in the international literature among neurologists and neurosurgeons that arachnoid cysts do harm and that the patients’ complaints can be relieved by surgical treatment.
Arachnoid Cysts: Epidemiology, Biology, and Neuroimaging gives a broad and updated presentation of the condition, including epidemiology, etiology, biology (including genetics and molecular biology), and neuroimaging of same. This book is written for researchers, residents, and clinical practitioners in clinical neuroscience, neurology, neurosurgery, neuroradiology, and pediatrics.
1. Part I: Introduction - p. xvi 2. Chapter 1. Arachnoid Cysts—Historical Perspectives and Controversial Aspects - p. 3 3. Part II: Biological Aspects - p. 15 4. Chapter 2. Arachnoid Cysts—Intracranial Locations, Gender, and Sidedness - p. 19 5. Chapter 3. Molecular Biology and Genetics: Gene Expression, Twin Studies and Familial Occurrence, and Syndromes Associated With AC - p. 27 6. Chapter 4. Arachnoid Cysts in Glutaric Aciduria Type I (GA-I) - p. 39 7. Chapter 5. Ultrastructure of Arachnoid Cysts - p. 57 8. Chapter 6. Pathophysiology of Intracranial Arachnoid Cysts: Hypoperfusion of Adjacent Cortex - p. 67 9. Chapter 7. Biochemistry—Composition of and Possible Mechanisms for Production of Arachnoid Cyst Fluid - p. 75 10. Chapter 8. The “Valve Mechanism” - p. 85 11. Part III: Prevalence and Natural History of Arachnoid Cysts - p. 92 12. Chapter 9. The Prevalence of Intracranial Arachnoid Cysts - p. 95 13. Chapter 10. Classification and Location of Arachnoid Cysts - p. 101 14. Chapter 11. Growth and Disappearance of Arachnoid Cysts - p. 111 15. Chapter 12. Arachnoid Cysts and Subdural and Intracystic Hematomas - p. 125 16. Chapter 13. Hydrocephalus Associated With Arachnoid Cysts - p. 139 17. Part IV: Neuroimaging - p. 166 18. Chapter 14. Radiological Workup, CT, MRI - p. 173 19. Chapter 15. Arachnoid Cyst—Prenatal Detection, Management, and Perinatal Outcome - p. 187 20. Chapter 16. SPECT Studies in Patients With Arachnoid Cysts - p. 199 21. Index - p. 215
