Atomic Force Microscopy for Nanoscale Biophysics: From Single Molecules to Living Cells summarizes the applications of atomic force microscopy for the investigation of biomolecules and cells. The book discusses the methodology of AFM-based biomedical detection, diverse biological systems, and the combination of AFM with other complementary techniques. These state-of-the-art chapters empower researchers to address biological issues through the application of atomic force microscopy. Atomic force microscopy (AFM) is a unique, multifunctional tool for investigating the structures and properties of living biological systems under aqueous conditions with unprecedented spatiotemporal resolution.
1. Cover image - p. Cover 2. Title page - p. ii 3. Copyright - p. ii 4. Table of Contents - p. iii 5. About the author - p. iii 6. Preface - p. ix 7. List of Illustrations - p. xii 8. List of Tables - p. xii 9. Chapter 1: Fundamentals and methods of atomic force microscopy for biophysics - p. xii 10. Chapter 2: Imaging and force detection of single deoxyribonucleic acid molecules by atomic force microscopy - p. 35 11. Chapter 3: High-resolution imaging and force spectroscopy of single membrane proteins by atomic force microscopy - p. 68 12. Chapter 4: Characterizing the nanostructures and mechanical properties of hydrogels by atomic force microscopy - p. 99 13. Chapter 5: Detecting the behaviors of single viruses by atomic force microscopy - p. 131 14. Chapter 6: Imaging and mechanical analysis of single native exosomes by atomic force microscopy - p. 156 15. Chapter 7: Nanoscale imaging and force probing of single microbial cells by atomic force microscopy - p. 182 16. Chapter 8: Investigating the structures and mechanics of single animal cells by atomic force microscopy - p. 213 17. Chapter 9: Characterizing the extracellular matrix for regulating cell behaviors by atomic force microscopy - p. 262 18. Chapter 10: Combining atomic force microscopy with complementary techniques for biophysics - p. 285 19. Chapter 11: Future perspectives of atomic force microscopy for biophysics - p. 306 20. Index - p. 313
Atomic Force Microscopy for Nanoscale Biophysics: From Single Molecules to Living Cells summarizes the applications of atomic force microscopy for the investigation of biomolecules and cells. The book discusses the methodology of AFM-based biomedical detection, diverse biological systems, and the combination of AFM with other complementary techniques. These state-of-the-art chapters empower researchers to address biological issues through the application of atomic force microscopy. Atomic force microscopy (AFM) is a unique, multifunctional tool for investigating the structures and properties of living biological systems under aqueous conditions with unprecedented spatiotemporal resolution.
1. Cover image - p. Cover 2. Title page - p. ii 3. Copyright - p. ii 4. Table of Contents - p. iii 5. About the author - p. iii 6. Preface - p. ix 7. List of Illustrations - p. xii 8. List of Tables - p. xii 9. Chapter 1: Fundamentals and methods of atomic force microscopy for biophysics - p. xii 10. Chapter 2: Imaging and force detection of single deoxyribonucleic acid molecules by atomic force microscopy - p. 35 11. Chapter 3: High-resolution imaging and force spectroscopy of single membrane proteins by atomic force microscopy - p. 68 12. Chapter 4: Characterizing the nanostructures and mechanical properties of hydrogels by atomic force microscopy - p. 99 13. Chapter 5: Detecting the behaviors of single viruses by atomic force microscopy - p. 131 14. Chapter 6: Imaging and mechanical analysis of single native exosomes by atomic force microscopy - p. 156 15. Chapter 7: Nanoscale imaging and force probing of single microbial cells by atomic force microscopy - p. 182 16. Chapter 8: Investigating the structures and mechanics of single animal cells by atomic force microscopy - p. 213 17. Chapter 9: Characterizing the extracellular matrix for regulating cell behaviors by atomic force microscopy - p. 262 18. Chapter 10: Combining atomic force microscopy with complementary techniques for biophysics - p. 285 19. Chapter 11: Future perspectives of atomic force microscopy for biophysics - p. 306 20. Index - p. 313
