Biochemical Immunology of Diabetes and Associated Complications offers in-depth coverage of the association of biochemical and immunological aspects of the human body in diabetes. It discusses the suppression and modulation of the immune system and the impact of immunochemicals on the biochemical pathways in diabetes, and associated complications. It enumerates the exigency in knowledge about the immunomodulators as therapeutic targets to cure the syndrome. This book will serve as an important reference for medical practitioners, researchers, medical students, masters and doctoral students of life sciences background. It could also be used as a reference book for science graduates, science teachers and researchers from academia and industry.
1. Introduction - p. Page xiii 2. List of Illustrations - p. Page xvi 3. List of Tables - p. Page xvii 4. Chapter 1 : Types of diabetes mellitus, mechanism of insulin resistance and associated complications - p. Page xvii 5. Chapter 2 : Immune system and diabetes mellitus - p. Page 16 6. Chapter 3 : Type-2 Diabetes Mellitus and its effect on immune system - p. Page 36 7. Chapter 4 : Association of oxidative stress and diabetes mellitus - p. Page 55 8. Chapter 5 : Biochemical pathways involved in diabetes mellitus - p. Page 70 9. Chapter 6 : Immune response and biochemical connection in diabetes mellitus - p. Page 96 10. Chapter 7 : Immunomodulatory therapy in diabetes mellitus: A pharmacological approach - p. Page 115 11. Chapter 8 : Targeting immune system for the treatment of diabetes mellitus - p. Page 136 12. Chapter 9 : GPCRs as therapeutic targets for the treatment of diabetes mellitus - p. Page 147 13. Chapter 10 : Biochemistry and immunology of inflammation-mediated responses in the development of diabetes mellitus - p. Page 165 14. Chapter 11 : Association of diabetes mellitus with stress, neuroinflammation, and other comorbid neuropsychiatric disorders: An immunological perspective - p. Page 192 15. Chapter 12 : Potent inflammatory biomarkers in insulin resistance - p. Page 221 16. Chapter 13 : Eliminating the knowledge gap of overlapped mechanisms of diabetes and neurological disorders - p. Page 243 17. Chapter 14 : Role of symbiotics in the treatment of diabetes mellitus via modification of the immune system - p. Page 281 18. Chapter 15 : Effect of current antidiabetic drugs on inflammation and immune system - p. Page 300 19. Chapter 16 : Lifestyle modifications and nutritional modulation of immune system for prevention and management of diabetes mellitus: Current perspectives - p. Page 309 20. Chapter 17 : Cellular and molecular mechanisms of the antidiabetic drugs under clinical trials - p. Page 325 21. Chapter 18 : Gut microbiota and diabetes: Exploring the intricate connection - p. Page 348 22. Glossary - p. Page 371 23. Index - p. Page 392
Biochemical Immunology of Diabetes and Associated Complications offers in-depth coverage of the association of biochemical and immunological aspects of the human body in diabetes. It discusses the suppression and modulation of the immune system and the impact of immunochemicals on the biochemical pathways in diabetes, and associated complications. It enumerates the exigency in knowledge about the immunomodulators as therapeutic targets to cure the syndrome. This book will serve as an important reference for medical practitioners, researchers, medical students, masters and doctoral students of life sciences background. It could also be used as a reference book for science graduates, science teachers and researchers from academia and industry.
1. Introduction - p. Page xiii 2. List of Illustrations - p. Page xvi 3. List of Tables - p. Page xvii 4. Chapter 1 : Types of diabetes mellitus, mechanism of insulin resistance and associated complications - p. Page xvii 5. Chapter 2 : Immune system and diabetes mellitus - p. Page 16 6. Chapter 3 : Type-2 Diabetes Mellitus and its effect on immune system - p. Page 36 7. Chapter 4 : Association of oxidative stress and diabetes mellitus - p. Page 55 8. Chapter 5 : Biochemical pathways involved in diabetes mellitus - p. Page 70 9. Chapter 6 : Immune response and biochemical connection in diabetes mellitus - p. Page 96 10. Chapter 7 : Immunomodulatory therapy in diabetes mellitus: A pharmacological approach - p. Page 115 11. Chapter 8 : Targeting immune system for the treatment of diabetes mellitus - p. Page 136 12. Chapter 9 : GPCRs as therapeutic targets for the treatment of diabetes mellitus - p. Page 147 13. Chapter 10 : Biochemistry and immunology of inflammation-mediated responses in the development of diabetes mellitus - p. Page 165 14. Chapter 11 : Association of diabetes mellitus with stress, neuroinflammation, and other comorbid neuropsychiatric disorders: An immunological perspective - p. Page 192 15. Chapter 12 : Potent inflammatory biomarkers in insulin resistance - p. Page 221 16. Chapter 13 : Eliminating the knowledge gap of overlapped mechanisms of diabetes and neurological disorders - p. Page 243 17. Chapter 14 : Role of symbiotics in the treatment of diabetes mellitus via modification of the immune system - p. Page 281 18. Chapter 15 : Effect of current antidiabetic drugs on inflammation and immune system - p. Page 300 19. Chapter 16 : Lifestyle modifications and nutritional modulation of immune system for prevention and management of diabetes mellitus: Current perspectives - p. Page 309 20. Chapter 17 : Cellular and molecular mechanisms of the antidiabetic drugs under clinical trials - p. Page 325 21. Chapter 18 : Gut microbiota and diabetes: Exploring the intricate connection - p. Page 348 22. Glossary - p. Page 371 23. Index - p. Page 392
