Biointegration of Medical Implant Materials, Second Edition, provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. New sections discuss soft tissue integration, with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, and vascular grafts. Other sections review tissue regeneration, inorganic nanoparticles for targeted drug delivery, alginate based drug delivery devices, and design considerations, with coverage of the biocompatibility of materials and their relevance to drug delivery and tissue engineering. With its distinguished editor and team of international contributors, this book is ideal for medical materials scientists and engineers in industry and academia.
1. 1. Biointegration: an introduction - p. 1 2. Part One. Soft tissue biointegration - p. 16 3. 2. Interface biology of stem cell–driven tissue engineering: concepts, concerns, and approaches - p. 19 4. 3. Replacement materials for facial reconstruction at the soft tissue–bone interface - p. 45 5. 4. Tissue engineering of small-diameter vascular grafts - p. 79 6. 5. Clinical applications of mesenchymal stem cells - p. 101 7. Part Two. Tissue regeneration - p. 116 8. 6. Cardiac regeneration - p. 119 9. 7. Tissue-based products - p. 145 10. 8. Tendon Regeneration - p. 187 11. 9. Integration of dental implants: molecular interplay and microbial transit at tissue–material interface - p. 221 12. 10. Biointegration of bone graft substiutes from osteointegration to osteotranduction - p. 245 13. 11. Stem cell–based therapeutic approaches toward corneal regeneration - p. 263 14. Part Three. Drug delivery - p. 294 15. 12. Biocompatibility of materials and its relevance to drug delivery and tissue engineering - p. 297 16. 13. Inorganic nanoparticles for targeted drug delivery - p. 333 17. 14. Applications of alginate biopolymer in drug delivery - p. 375 18. Part Four. Design considerations - p. 403 19. 15. Failure mechanisms of medical implants and their effects on outcomes - p. 407 20. 16. Biointegration of three-dimensional–printed biomaterials and biomedical devices - p. 433 21. Index - p. 483
Biointegration of Medical Implant Materials, Second Edition, provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. New sections discuss soft tissue integration, with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, and vascular grafts. Other sections review tissue regeneration, inorganic nanoparticles for targeted drug delivery, alginate based drug delivery devices, and design considerations, with coverage of the biocompatibility of materials and their relevance to drug delivery and tissue engineering. With its distinguished editor and team of international contributors, this book is ideal for medical materials scientists and engineers in industry and academia.
1. 1. Biointegration: an introduction - p. 1 2. Part One. Soft tissue biointegration - p. 16 3. 2. Interface biology of stem cell–driven tissue engineering: concepts, concerns, and approaches - p. 19 4. 3. Replacement materials for facial reconstruction at the soft tissue–bone interface - p. 45 5. 4. Tissue engineering of small-diameter vascular grafts - p. 79 6. 5. Clinical applications of mesenchymal stem cells - p. 101 7. Part Two. Tissue regeneration - p. 116 8. 6. Cardiac regeneration - p. 119 9. 7. Tissue-based products - p. 145 10. 8. Tendon Regeneration - p. 187 11. 9. Integration of dental implants: molecular interplay and microbial transit at tissue–material interface - p. 221 12. 10. Biointegration of bone graft substiutes from osteointegration to osteotranduction - p. 245 13. 11. Stem cell–based therapeutic approaches toward corneal regeneration - p. 263 14. Part Three. Drug delivery - p. 294 15. 12. Biocompatibility of materials and its relevance to drug delivery and tissue engineering - p. 297 16. 13. Inorganic nanoparticles for targeted drug delivery - p. 333 17. 14. Applications of alginate biopolymer in drug delivery - p. 375 18. Part Four. Design considerations - p. 403 19. 15. Failure mechanisms of medical implants and their effects on outcomes - p. 407 20. 16. Biointegration of three-dimensional–printed biomaterials and biomedical devices - p. 433 21. Index - p. 483
