Biologically Active Peptides: From Basic Science to Applications for Human Health stands as a comprehensive resource on bioactive peptide science and applications. With contributions from more than thirty global experts, topics discussed include bioactive peptide science, structure-activity relationships, best practices for their study and production, and their applications. In the interdisciplinary field of bioactive peptides, this book bridges the gap between basic peptide chemistry and human physiology, while reviewing recent advances in peptide analysis and characterization. Methods and technology-driven chapters offer step-by-step guidance in peptide preparation from different source materials, bioactivity assays, analysis and identification of bioactive peptides, encoding bioactive peptides.
Later, applications across disease areas and medical specialties are examined in-depth, including the use of bioactive peptides in treating obesity, diabetes, osteoporosis, mental health disorders, food allergies, and joint health, among other disorders, as well as bioactive peptides for sensory enhancement, sports and clinical nutrition, lowering cholesterol, improving cardiovascular health, and driving advances in biotechnology.
1. Biologically Active Peptides - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. Preface - p. Page vii 9. List of Illustrations - p. Page x 10. List of Tables - p. Page xi 11. Chapter 1 : Bioactive peptides in health and disease: an overview - p. Page xi 12. Chapter 2 : Enzymatic mechanisms for the generation of bioactive peptides - p. Page 18 13. Chapter 3 : Novel technologies in bioactive peptides production and stability - p. Page 42 14. Chapter 4 : Methodologies for extraction and separation of short-chain bioactive peptides - p. Page 71 15. Chapter 5 : Methodologies for peptidomics: Identification and quantification - p. Page 84 16. Chapter 6 : Methodologies for bioactivity assay: biochemical study - p. Page 101 17. Chapter 7 : Methodologies for bioactivity assay: cell study - p. Page 141 18. Chapter 8 : Methodologies for bioactivity assay: animal study - p. Page 186 19. Chapter 9 : Methodologies for bioavailability assessment of food-derived peptide - p. Page 212 20. Chapter 10 : Methodologies for studying the structure–function relationship of food-derived peptides with biological activities - p. Page 234 21. Chapter 11 : Methodologies for investigating the vasorelaxation action of peptides - p. Page 249 22. Chapter 12 : Methodologies for studying mechanisms of action of bioactive peptides: a multiomic approach - p. Page 273 23. Chapter 13 : CRISPR–Cas systems in bioactive peptide research - p. Page 283 24. Chapter 14 : Databases of bioactive peptides - p. Page 300 25. Chapter 15 : Encapsulation technology for protection and delivery of bioactive peptides - p. Page 325 26. Chapter 16 : Plant sources of bioactive peptides - p. Page 352 27. Chapter 17 : Generation of bioactivities from proteins of animal sources by enzymatic hydrolysis and the Maillard reaction - p. Page 386 28. Chapter 18 : Sustainable, alternative sources of bioactive peptides - p. Page 418 29. Chapter 19 : Application in nutrition: mineral binding - p. Page 445 30. Chapter 20 : Applications in nutrition: clinical nutrition - p. Page 483 31. Chapter 21 : Applications in nutrition: sport nutrition - p. Page 518 32. Chapter 22 : Application in nutrition: cholesterol-lowering activity - p. Page 542 33. Chapter 23 : Applications in nutrition: Peptides as taste enhancers - p. Page 563 34. Chapter 24 : Cardiovascular benefits of food protein-derived bioactive peptides - p. Page 577 35. Chapter 25 : Applications in medicine: hypoglycemic peptides - p. Page 602 36. Chapter 26 : Application in medicine: obesity and satiety control - p. Page 623 37. Chapter 27 : Food-derived osteogenic peptides towards osteoporosis - p. Page 656 38. Chapter 28 : Applications in medicine: mental health - p. Page 682 39. Chapter 29 : Applications in medicine: joint health - p. Page 712 40. Chapter 30 : Applications in food technology: antimicrobial peptides - p. Page 741 41. Index - p. Page 764
Biologically Active Peptides: From Basic Science to Applications for Human Health stands as a comprehensive resource on bioactive peptide science and applications. With contributions from more than thirty global experts, topics discussed include bioactive peptide science, structure-activity relationships, best practices for their study and production, and their applications. In the interdisciplinary field of bioactive peptides, this book bridges the gap between basic peptide chemistry and human physiology, while reviewing recent advances in peptide analysis and characterization. Methods and technology-driven chapters offer step-by-step guidance in peptide preparation from different source materials, bioactivity assays, analysis and identification of bioactive peptides, encoding bioactive peptides.
Later, applications across disease areas and medical specialties are examined in-depth, including the use of bioactive peptides in treating obesity, diabetes, osteoporosis, mental health disorders, food allergies, and joint health, among other disorders, as well as bioactive peptides for sensory enhancement, sports and clinical nutrition, lowering cholesterol, improving cardiovascular health, and driving advances in biotechnology.
1. Biologically Active Peptides - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. Preface - p. Page vii 9. List of Illustrations - p. Page x 10. List of Tables - p. Page xi 11. Chapter 1 : Bioactive peptides in health and disease: an overview - p. Page xi 12. Chapter 2 : Enzymatic mechanisms for the generation of bioactive peptides - p. Page 18 13. Chapter 3 : Novel technologies in bioactive peptides production and stability - p. Page 42 14. Chapter 4 : Methodologies for extraction and separation of short-chain bioactive peptides - p. Page 71 15. Chapter 5 : Methodologies for peptidomics: Identification and quantification - p. Page 84 16. Chapter 6 : Methodologies for bioactivity assay: biochemical study - p. Page 101 17. Chapter 7 : Methodologies for bioactivity assay: cell study - p. Page 141 18. Chapter 8 : Methodologies for bioactivity assay: animal study - p. Page 186 19. Chapter 9 : Methodologies for bioavailability assessment of food-derived peptide - p. Page 212 20. Chapter 10 : Methodologies for studying the structure–function relationship of food-derived peptides with biological activities - p. Page 234 21. Chapter 11 : Methodologies for investigating the vasorelaxation action of peptides - p. Page 249 22. Chapter 12 : Methodologies for studying mechanisms of action of bioactive peptides: a multiomic approach - p. Page 273 23. Chapter 13 : CRISPR–Cas systems in bioactive peptide research - p. Page 283 24. Chapter 14 : Databases of bioactive peptides - p. Page 300 25. Chapter 15 : Encapsulation technology for protection and delivery of bioactive peptides - p. Page 325 26. Chapter 16 : Plant sources of bioactive peptides - p. Page 352 27. Chapter 17 : Generation of bioactivities from proteins of animal sources by enzymatic hydrolysis and the Maillard reaction - p. Page 386 28. Chapter 18 : Sustainable, alternative sources of bioactive peptides - p. Page 418 29. Chapter 19 : Application in nutrition: mineral binding - p. Page 445 30. Chapter 20 : Applications in nutrition: clinical nutrition - p. Page 483 31. Chapter 21 : Applications in nutrition: sport nutrition - p. Page 518 32. Chapter 22 : Application in nutrition: cholesterol-lowering activity - p. Page 542 33. Chapter 23 : Applications in nutrition: Peptides as taste enhancers - p. Page 563 34. Chapter 24 : Cardiovascular benefits of food protein-derived bioactive peptides - p. Page 577 35. Chapter 25 : Applications in medicine: hypoglycemic peptides - p. Page 602 36. Chapter 26 : Application in medicine: obesity and satiety control - p. Page 623 37. Chapter 27 : Food-derived osteogenic peptides towards osteoporosis - p. Page 656 38. Chapter 28 : Applications in medicine: mental health - p. Page 682 39. Chapter 29 : Applications in medicine: joint health - p. Page 712 40. Chapter 30 : Applications in food technology: antimicrobial peptides - p. Page 741 41. Index - p. Page 764