Biosensors for Single-Cell Analysis explores a wide range of biosensor technologies and their applications in single-cell characterization and analysis. Sections cover key biophysical and chemical single-cell properties that consider proteomic, metabolic, electrical, mechanical and optical properties. Each chapter features key definitions and case studies, providing detailed guidance for researchers who want to replicate covered solutions in their work. Tutorial sections, evaluations of the current state-of-the-field and future developments are also included. Microfluidic approaches to characterization, such as microfluidic impedance flow cytometry and microfluidic flow cytometry are considered alongside more conventional approaches, such as mass spectroscopy, fluorescent and mass flow cytometry.
Additionally, key types of biosensors are covered, including atomic force microscopy, micropipette aspiration, optical tweezers, microfluidic hydrodynamic stretchers, microfluidic constriction channel and microfluidic optical stretchers.
1. Chapter 1 Introduction to biosensors for single-cell analysis with historical developments highlighted - p. 1 2. Chapter 2 Biosensors for single-cell proteomic characterization - p. 7 3. Chapter 3 Biosensors for single-cell metabolomic characterization - p. 37 4. Chapter 4 Single-cell electrical characterization - p. 71 5. Chapter 5 Biosensors for single-cell mechanical characterization - p. 101 6. Chapter 6 Single-cell analysis by evanescent wave sensing and hyperspectral microscopy - p. 125 7. Chapter 7 Future directions of biosensors for single-cell analysis from the perspective of instrument developments - p. 159 8. Index - p. 165
Biosensors for Single-Cell Analysis explores a wide range of biosensor technologies and their applications in single-cell characterization and analysis. Sections cover key biophysical and chemical single-cell properties that consider proteomic, metabolic, electrical, mechanical and optical properties. Each chapter features key definitions and case studies, providing detailed guidance for researchers who want to replicate covered solutions in their work. Tutorial sections, evaluations of the current state-of-the-field and future developments are also included. Microfluidic approaches to characterization, such as microfluidic impedance flow cytometry and microfluidic flow cytometry are considered alongside more conventional approaches, such as mass spectroscopy, fluorescent and mass flow cytometry.
Additionally, key types of biosensors are covered, including atomic force microscopy, micropipette aspiration, optical tweezers, microfluidic hydrodynamic stretchers, microfluidic constriction channel and microfluidic optical stretchers.
1. Chapter 1 Introduction to biosensors for single-cell analysis with historical developments highlighted - p. 1 2. Chapter 2 Biosensors for single-cell proteomic characterization - p. 7 3. Chapter 3 Biosensors for single-cell metabolomic characterization - p. 37 4. Chapter 4 Single-cell electrical characterization - p. 71 5. Chapter 5 Biosensors for single-cell mechanical characterization - p. 101 6. Chapter 6 Single-cell analysis by evanescent wave sensing and hyperspectral microscopy - p. 125 7. Chapter 7 Future directions of biosensors for single-cell analysis from the perspective of instrument developments - p. 159 8. Index - p. 165
