Plants are a source of bioactive compounds and specialty chemicals such as ginsenosides; paclitaxel, artemisinin, veregen and nutraceuticals. Biopharmaceuticals are important in human healthcare, and herbal actives are gaining importance all over the world. With natural resources dwindling, in vitro production of secondary compounds on a commercial scale is being more and more required.
The difficulties that are increasingly encountered in procuring ample supply of raw plant material because of drastic decrease in natural resources have prompted the adaptation of in vitro technology for commercial production of substances of medicinal importance. Besides providing an alternative technology to bypass the above difficulties, the plant tissue culture (used in a broad sense to include cell, tissue and organ culture) offers many advantages. In vitro technology also facilitates novel means of conserving the genetic diversity of the germplasm of medicinal plants through cryopreservation, and production of novel compounds through biotransformation, somatic hybridization and selective gene transfer through recombinant DNA technology for enhancing the metabolite production.
Biotechnological production of bioactive phytochemicals of medicinal value covers a broad variety of methods for secondary metabolites production (both pharmaceuticals and cosmeceuticals), compiling state-of-the-art material about the current knowledge of in vitro production for a large number of bioactive phytochemicals.
1. Biotechnological Production of Bioactive Phytochemicals of Medicinal Value - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. Preface - p. Page vii 9. List of Illustrations - p. Page x 10. List of Tables - p. Page xi 11. Chapter 1 : Plants to pharmacy: recapitulation of natural compounds transmuting human health - p. Page xi 12. Chapter 2 : Production of bioactive metabolites in in vitro cultures of saffron (Crocus sativus L.) - p. Page 10 13. Chapter 3 : In vitro production of industrial valued bioactive secondary metabolites from selected medicinal plants of Sri Lanka - p. Page 57 14. Chapter 4 : In vitro production of secondary metabolites by Thymus plants - p. Page 93 15. Chapter 5 : In vitro production of anthocyanins - p. Page 118 16. Chapter 6 : Prospecting phytochemical and biological of seedling extract of Libidibia ferrea (Fabaceae) produced from in vitro propagation - p. Page 141 17. Chapter 7 : Properties, biotechnological production, and applications of rhinacanthins - p. Page 160 18. Chapter 8 : Nanoparticle-mediated elicitation of plant secondary metabolites, in vitro and in vivo - p. Page 187 19. Chapter 9 : Recent trends in in vitro production of alkaloids from Rauvolfia serpentina - p. Page 212 20. Chapter 10 : Experimental strategies to enhance in vitro production of plant secondary metabolites - p. Page 238 21. Chapter 11 : An overview of the in vitro synthesis of anthraquinones in plant cell and organ cultures and elicitation strategies - p. Page 264 22. Chapter 12 : Secondary metabolite production in transgenic cultures: an overview over the last decade - p. Page 300 23. Chapter 13 : In vitro production of phytoecdysteroids in plants - p. Page 325 24. Chapter 14 : Bacosides neurotropic molecules production by tissue cultures of Bacopa monnieri (L.) Wettst. - p. Page 347 25. Chapter 15 : Application of different tissue culture techniques for in vitro production of gymnemic acid: factors, approaches, and challenges to achieve higher yield - p. Page 368 26. Chapter 16 : Adoption of biotechnologies for Withania somnifera (L.) Dunal for sustainable utilization - p. Page 386 27. Chapter 17 : In vitro cultures of some Asclepiadaceae members: a source for the production of secondary metabolites - p. Page 408 28. Chapter 18 : In vitro studies and hairy root development with reference to secondary metabolite production in medicinally important Solanum erianthum D. Don - p. Page 435 29. Chapter 19 : A nonsteroidal antiinflammatory drug boswellic acid from Boswellia serrata Roxb. - p. Page 452 30. Chapter 20 : Accumulation of anticancer compounds in cultured cells and hairy roots - p. Page 468 31. Chapter 21 : Applications of radiations and mutagenesis for the enhancement of plant secondary metabolites - p. Page 498 32. Chapter 22 : In vitro hepatoprotective lignan production from Phyllanthus species - p. Page 522 33. Chapter 23 : Cardiotonic glycosides production in Digitalis: application of in vitro culture and transgenic approaches - p. Page 549 34. Chapter 24 : Production of bioactive compounds from cell and organ cultures of Centella asiatica - p. Page 579 35. Index - p. Page 600
Plants are a source of bioactive compounds and specialty chemicals such as ginsenosides; paclitaxel, artemisinin, veregen and nutraceuticals. Biopharmaceuticals are important in human healthcare, and herbal actives are gaining importance all over the world. With natural resources dwindling, in vitro production of secondary compounds on a commercial scale is being more and more required.
The difficulties that are increasingly encountered in procuring ample supply of raw plant material because of drastic decrease in natural resources have prompted the adaptation of in vitro technology for commercial production of substances of medicinal importance. Besides providing an alternative technology to bypass the above difficulties, the plant tissue culture (used in a broad sense to include cell, tissue and organ culture) offers many advantages. In vitro technology also facilitates novel means of conserving the genetic diversity of the germplasm of medicinal plants through cryopreservation, and production of novel compounds through biotransformation, somatic hybridization and selective gene transfer through recombinant DNA technology for enhancing the metabolite production.
Biotechnological production of bioactive phytochemicals of medicinal value covers a broad variety of methods for secondary metabolites production (both pharmaceuticals and cosmeceuticals), compiling state-of-the-art material about the current knowledge of in vitro production for a large number of bioactive phytochemicals.
1. Biotechnological Production of Bioactive Phytochemicals of Medicinal Value - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. Preface - p. Page vii 9. List of Illustrations - p. Page x 10. List of Tables - p. Page xi 11. Chapter 1 : Plants to pharmacy: recapitulation of natural compounds transmuting human health - p. Page xi 12. Chapter 2 : Production of bioactive metabolites in in vitro cultures of saffron (Crocus sativus L.) - p. Page 10 13. Chapter 3 : In vitro production of industrial valued bioactive secondary metabolites from selected medicinal plants of Sri Lanka - p. Page 57 14. Chapter 4 : In vitro production of secondary metabolites by Thymus plants - p. Page 93 15. Chapter 5 : In vitro production of anthocyanins - p. Page 118 16. Chapter 6 : Prospecting phytochemical and biological of seedling extract of Libidibia ferrea (Fabaceae) produced from in vitro propagation - p. Page 141 17. Chapter 7 : Properties, biotechnological production, and applications of rhinacanthins - p. Page 160 18. Chapter 8 : Nanoparticle-mediated elicitation of plant secondary metabolites, in vitro and in vivo - p. Page 187 19. Chapter 9 : Recent trends in in vitro production of alkaloids from Rauvolfia serpentina - p. Page 212 20. Chapter 10 : Experimental strategies to enhance in vitro production of plant secondary metabolites - p. Page 238 21. Chapter 11 : An overview of the in vitro synthesis of anthraquinones in plant cell and organ cultures and elicitation strategies - p. Page 264 22. Chapter 12 : Secondary metabolite production in transgenic cultures: an overview over the last decade - p. Page 300 23. Chapter 13 : In vitro production of phytoecdysteroids in plants - p. Page 325 24. Chapter 14 : Bacosides neurotropic molecules production by tissue cultures of Bacopa monnieri (L.) Wettst. - p. Page 347 25. Chapter 15 : Application of different tissue culture techniques for in vitro production of gymnemic acid: factors, approaches, and challenges to achieve higher yield - p. Page 368 26. Chapter 16 : Adoption of biotechnologies for Withania somnifera (L.) Dunal for sustainable utilization - p. Page 386 27. Chapter 17 : In vitro cultures of some Asclepiadaceae members: a source for the production of secondary metabolites - p. Page 408 28. Chapter 18 : In vitro studies and hairy root development with reference to secondary metabolite production in medicinally important Solanum erianthum D. Don - p. Page 435 29. Chapter 19 : A nonsteroidal antiinflammatory drug boswellic acid from Boswellia serrata Roxb. - p. Page 452 30. Chapter 20 : Accumulation of anticancer compounds in cultured cells and hairy roots - p. Page 468 31. Chapter 21 : Applications of radiations and mutagenesis for the enhancement of plant secondary metabolites - p. Page 498 32. Chapter 22 : In vitro hepatoprotective lignan production from Phyllanthus species - p. Page 522 33. Chapter 23 : Cardiotonic glycosides production in Digitalis: application of in vitro culture and transgenic approaches - p. Page 549 34. Chapter 24 : Production of bioactive compounds from cell and organ cultures of Centella asiatica - p. Page 579 35. Index - p. Page 600
