Cancer of the Skin is your complete guide to early diagnosis and effective medical and surgical treatment of melanoma and other skin cancers. Thoroughly updated with 11 new chapters, and a new, multi-disciplinary team of contributors and editors comprised of leading experts in this field, this Second Edition offers truly diverse perspectives and worldwide best practices.
1. Cover image - p. cover 2. Title page - p. iii 3. Table of Contents - p. v 4. Copyright - p. iv 5. Foreword - p. viii 6. Preface - p. ix 7. List of Contributors - p. x 8. Dedication & Acknowledgements - p. xv 9. Videos - p. xv 10. Part 1: Basic skin cancer biology and epidemiology - p. 1 11. List of Illustrations - p. 1 12. List of Tables - p. 1 13. Chapter 1: The Biology of Skin Cancer Invasion and Metastasis - p. 1 14. Chapter 2: Genetics of Skin Cancer - p. 12 15. Chapter 3: The Biology of the Melanocyte - p. 23 16. Chapter 4: Skin Cancer: Burden of Disease - p. 40 17. Chapter 5: Epidemiology of Skin Cancer - p. 44 18. Chapter 6: Etiological Factors in Skin Cancers: Environmental and Biological - p. 56 19. Chapter 7: The Importance of Primary and Secondary Prevention Programs for Skin Cancer - p. 66 20. Chapter 8: Chemoprevention of Skin Cancers - p. 73 21. Chapter 9: Current Concepts in Photoprotection - p. 80 22. Part 2: Non-melanoma - p. 89 23. Chapter 10: Actinic Keratoses and Other Precursors of Keratinocytic Cutaneous Malignancies - p. 89 24. Chapter 11: Basal Cell Carcinoma - p. 99 25. Chapter 12: Squamous Cell Carcinoma - p. 124 26. Chapter 13: Adnexal Carcinomas of the Skin - p. 140 27. Chapter 14: Paget’s Disease - p. 150 28. Chapter 15: Sarcomas of the Skin - p. 157 29. Chapter 16: Kaposi’s Sarcoma - p. 168 30. Chapter 17: Merkel Cell Carcinoma - p. 179 31. Chapter 18: Malignant Neoplasms: Vascular Differentiation - p. 186 32. Chapter 19: Cutaneous Neoplastic Disorders Related to HPV and HIV Infection - p. 196 33. Chapter 20: Pseudolymphomas of the Skin - p. 207 34. Chapter 21: Cutaneous T-cell Lymphoma: Mycosis Fungoides and Sézary Syndrome - p. 217 35. Part 3: Melanoma and related melanocytic neoplasms - p. 231 36. Chapter 22: Dysplastic Nevi - p. 231 37. Chapter 23: Congenital Melanocytic Nevi - p. 246 38. Chapter 24: The Many Faces of Melanoma - p. 262 39. Chapter 25: The Importance of Early Detection of Melanoma, Physician and Self-Examination - p. 272 40. Chapter 26: Prognostic Factors and Staging in Melanoma - p. 282 41. Chapter 27: Pathology of Melanoma: Interpretation and New Concepts - p. 295 42. Chapter 28: Management of the Patient with Melanoma - p. 318 43. Chapter 29: Pregnancy and Melanoma - p. 327 44. Chapter 30: Genetic Testing for Melanoma - p. 334 45. Part 4: Other cancers of the skin and related issues - p. 341 46. Chapter 31: Spitz nevus - p. 341 47. Chapter 32: Cutaneous Carcinogenesis Related to Dermatologic Therapy - p. 349 48. Chapter 33: Genetic Disorders Predisposing to Skin Malignancy - p. 357 49. Chapter 34: Dermatologic Manifestations of Internal Malignancy - p. 367 50. Chapter 35: Dermatologic Manifestations of Systemic Oncologic Therapy of Cutaneous Malignancies - p. 379 51. Part 5: New approaches - p. 386 52. Chapter 36: The Dermoscopic Patterns of Melanoma and Non-Melanoma Skin Cancer - p. 386 53. Chapter 37: Computer-Aided Diagnosis for Cutaneous Melanoma - p. 400 54. Chapter 38: Confocal Microscopy in Skin Cancer - p. 407 55. Chapter 39: Clinical Genomics for Melanoma Detection - p. 429 56. Part 6: Therapeutic considerations in the management of patients with cancer of the skin - p. 434 57. Chapter 40: Biopsy Techniques - p. 434 58. Chapter 41: Curettage and Electrodesiccation - p. 443 59. Chapter 42: Cryosurgery - p. 450 60. Chapter 43: Topical Treatment of Skin Cancer - p. 462 61. Chapter 44: Immune Response Modulators in the Treatment of Skin Cancer - p. 477 62. Chapter 45: Photodynamic Therapy in Skin Cancer - p. 497 63. Chapter 46: Surgical Excision for Non-Melanoma Skin Cancer - p. 508 64. Chapter 47: Mohs Surgery - p. 515 65. Chapter 48: Treatment of Disseminated Non-Melanoma Skin Cancers - p. 526 66. Chapter 49: Surgical Excision of Melanoma - p. 532 67. Chapter 50: Regional Lymph Node Surgery in Melanoma Patients - p. 544 68. Chapter 51: Reconstructive Surgery for Skin Cancer - p. 559 69. Chapter 52: Radiation Therapy in the Treatment of Skin Cancers - p. 576 70. Chapter 53: Adjuvant Therapy for Cutaneous Melanoma - p. 589 71. Chapter 54: Vaccine Therapy for Melanoma - p. 606 72. Chapter 55: Targeted Therapy for Melanoma - p. 613 73. Chapter 56: Imaging Work-up of the Patient with Melanoma - p. 623 74. Chapter 57: Treatment of Disseminated Melanoma - p. 629 75. Chapter 58: Management of Skin Cancer in the Immunocompromised Patient - p. 634 76. Part 7: Other aspects of skin cancer - p. 644 77. Chapter 59: Indoor Tanning - p. 644 78. Chapter 60: Vitamin D and UV: Risks and Benefits - p. 650 79. Chapter 61: Photography in Skin Cancer Treatment - p. 657 80. Chapter 62: Psychological Responses and Coping Strategies in Skin Cancer Patients - p. 662 81. Chapter 63: Medical and Legal Aspects of Skin Cancer Patients - p. 668 82. Index - p. 677
Cancer of the Skin is your complete guide to early diagnosis and effective medical and surgical treatment of melanoma and other skin cancers. Thoroughly updated with 11 new chapters, and a new, multi-disciplinary team of contributors and editors comprised of leading experts in this field, this Second Edition offers truly diverse perspectives and worldwide best practices.
1. Cover image - p. cover 2. Title page - p. iii 3. Table of Contents - p. v 4. Copyright - p. iv 5. Foreword - p. viii 6. Preface - p. ix 7. List of Contributors - p. x 8. Dedication & Acknowledgements - p. xv 9. Videos - p. xv 10. Part 1: Basic skin cancer biology and epidemiology - p. 1 11. List of Illustrations - p. 1 12. List of Tables - p. 1 13. Chapter 1: The Biology of Skin Cancer Invasion and Metastasis - p. 1 14. Chapter 2: Genetics of Skin Cancer - p. 12 15. Chapter 3: The Biology of the Melanocyte - p. 23 16. Chapter 4: Skin Cancer: Burden of Disease - p. 40 17. Chapter 5: Epidemiology of Skin Cancer - p. 44 18. Chapter 6: Etiological Factors in Skin Cancers: Environmental and Biological - p. 56 19. Chapter 7: The Importance of Primary and Secondary Prevention Programs for Skin Cancer - p. 66 20. Chapter 8: Chemoprevention of Skin Cancers - p. 73 21. Chapter 9: Current Concepts in Photoprotection - p. 80 22. Part 2: Non-melanoma - p. 89 23. Chapter 10: Actinic Keratoses and Other Precursors of Keratinocytic Cutaneous Malignancies - p. 89 24. Chapter 11: Basal Cell Carcinoma - p. 99 25. Chapter 12: Squamous Cell Carcinoma - p. 124 26. Chapter 13: Adnexal Carcinomas of the Skin - p. 140 27. Chapter 14: Paget’s Disease - p. 150 28. Chapter 15: Sarcomas of the Skin - p. 157 29. Chapter 16: Kaposi’s Sarcoma - p. 168 30. Chapter 17: Merkel Cell Carcinoma - p. 179 31. Chapter 18: Malignant Neoplasms: Vascular Differentiation - p. 186 32. Chapter 19: Cutaneous Neoplastic Disorders Related to HPV and HIV Infection - p. 196 33. Chapter 20: Pseudolymphomas of the Skin - p. 207 34. Chapter 21: Cutaneous T-cell Lymphoma: Mycosis Fungoides and Sézary Syndrome - p. 217 35. Part 3: Melanoma and related melanocytic neoplasms - p. 231 36. Chapter 22: Dysplastic Nevi - p. 231 37. Chapter 23: Congenital Melanocytic Nevi - p. 246 38. Chapter 24: The Many Faces of Melanoma - p. 262 39. Chapter 25: The Importance of Early Detection of Melanoma, Physician and Self-Examination - p. 272 40. Chapter 26: Prognostic Factors and Staging in Melanoma - p. 282 41. Chapter 27: Pathology of Melanoma: Interpretation and New Concepts - p. 295 42. Chapter 28: Management of the Patient with Melanoma - p. 318 43. Chapter 29: Pregnancy and Melanoma - p. 327 44. Chapter 30: Genetic Testing for Melanoma - p. 334 45. Part 4: Other cancers of the skin and related issues - p. 341 46. Chapter 31: Spitz nevus - p. 341 47. Chapter 32: Cutaneous Carcinogenesis Related to Dermatologic Therapy - p. 349 48. Chapter 33: Genetic Disorders Predisposing to Skin Malignancy - p. 357 49. Chapter 34: Dermatologic Manifestations of Internal Malignancy - p. 367 50. Chapter 35: Dermatologic Manifestations of Systemic Oncologic Therapy of Cutaneous Malignancies - p. 379 51. Part 5: New approaches - p. 386 52. Chapter 36: The Dermoscopic Patterns of Melanoma and Non-Melanoma Skin Cancer - p. 386 53. Chapter 37: Computer-Aided Diagnosis for Cutaneous Melanoma - p. 400 54. Chapter 38: Confocal Microscopy in Skin Cancer - p. 407 55. Chapter 39: Clinical Genomics for Melanoma Detection - p. 429 56. Part 6: Therapeutic considerations in the management of patients with cancer of the skin - p. 434 57. Chapter 40: Biopsy Techniques - p. 434 58. Chapter 41: Curettage and Electrodesiccation - p. 443 59. Chapter 42: Cryosurgery - p. 450 60. Chapter 43: Topical Treatment of Skin Cancer - p. 462 61. Chapter 44: Immune Response Modulators in the Treatment of Skin Cancer - p. 477 62. Chapter 45: Photodynamic Therapy in Skin Cancer - p. 497 63. Chapter 46: Surgical Excision for Non-Melanoma Skin Cancer - p. 508 64. Chapter 47: Mohs Surgery - p. 515 65. Chapter 48: Treatment of Disseminated Non-Melanoma Skin Cancers - p. 526 66. Chapter 49: Surgical Excision of Melanoma - p. 532 67. Chapter 50: Regional Lymph Node Surgery in Melanoma Patients - p. 544 68. Chapter 51: Reconstructive Surgery for Skin Cancer - p. 559 69. Chapter 52: Radiation Therapy in the Treatment of Skin Cancers - p. 576 70. Chapter 53: Adjuvant Therapy for Cutaneous Melanoma - p. 589 71. Chapter 54: Vaccine Therapy for Melanoma - p. 606 72. Chapter 55: Targeted Therapy for Melanoma - p. 613 73. Chapter 56: Imaging Work-up of the Patient with Melanoma - p. 623 74. Chapter 57: Treatment of Disseminated Melanoma - p. 629 75. Chapter 58: Management of Skin Cancer in the Immunocompromised Patient - p. 634 76. Part 7: Other aspects of skin cancer - p. 644 77. Chapter 59: Indoor Tanning - p. 644 78. Chapter 60: Vitamin D and UV: Risks and Benefits - p. 650 79. Chapter 61: Photography in Skin Cancer Treatment - p. 657 80. Chapter 62: Psychological Responses and Coping Strategies in Skin Cancer Patients - p. 662 81. Chapter 63: Medical and Legal Aspects of Skin Cancer Patients - p. 668 82. Index - p. 677
