Cardiopulmonary Bypass: Advancements in Extracorporeal Life Support provides comprehensive coverage on the technological developments and clinical applications of extracorporeal technologies, including the underlying basic science and the latest clinical advances in the field. Written by experts around the world, this book comprises all characteristics of cardiopulmonary bypass as well as chapters regarding equipment, physiology and pathology, pediatric aspects and clinical applications. Important highlights include the latest updates regarding minimal invasive cardiopulmonary bypass (MICPB), extracorporeal circulatory and respiratory support (ECCRS) in cardiac and non-cardiac patients, ECMO support in COVID-19, and updated guidelines of extracorporeal technologies.
This book is an invaluable resource to clinicians, researchers and medical students in the fields of cardiothoracic surgery, cardiac anesthesiology, intensive care, and perfusion technology.
1. Chapter 1: Introduction to “surgical perspective” - p. lxxxi 2. Chapter 2: Introduction for “perfusional perspective” - p. 4 3. Part II: Artificial circulation and respiration - p. 6 4. Chapter 3: Development of artificial circulation - p. 6 5. Chapter 4: Future artificial surface physiology - p. 20 6. Chapter 5: Evolution of mechanical cardiac support - p. 31 7. Chapter 6: The future of artificial lung - p. 50 8. Chapter 7: Future noninvasive monitoring - p. 61 9. Chapter 8: Three-dimensional printing in cardiopulmonary disease - p. 79 10. Chapter 9: Guidelines for extracorporeal circulation - p. 103 11. Part III: Cardiopulmonary bypass (CPB) - p. 118 12. Chapter 10: Basics of extracorporeal circulation - p. 118 13. Chapter 11: Pathophysiology of cardiopulmonary bypass - p. 131 14. Chapter 12: Microcirculation during cardiopulmonary bypass - p. 151 15. Chapter 13: Perfusion standards and guidelines - p. 161 16. Chapter 14: Mechanical pumps for cardiopulmonary bypass - p. 178 17. Chapter 15: Oxygenators for extracorporeal circulation: theory and practice fundamentals for clinicians - p. 187 18. Chapter 16: Cannulations for cardiopulmonary bypass - p. 218 19. Chapter 17: Anesthesia during cardiopulmonary bypass - p. 234 20. Chapter 18: Monitoring during cardiopulmonary bypass - p. 254 21. Chapter 19: Transesophageal echocardiography and cardiopulmonary bypass - p. 282 22. Chapter 20: Hemostasis during cardiopulmonary bypass - p. 293 23. Chapter 21: Myocardial preservation during cardiopulmonary bypass - p. 307 24. Chapter 22: Cerebral preservation during deep hypothermic circulatory arrest in cardiopulmonary bypass - p. 325 25. Part IV: Special cardiopulmonary bypass - p. 338 26. Chapter 23: Cardiopulmonary bypass in pregnancy - p. 338 27. Chapter 24: Cardiopulmonary bypass in neonates and infants - p. 354 28. Chapter 25: Cardiopulmonary bypass in pediatrics - p. 376 29. Chapter 26: Cardiopulmonary bypass in thoracic aortic surgery - p. 392 30. Chapter 27: Cardiopulmonary bypass in lung transplantation - p. 416 31. Chapter 28: Cardiopulmonary bypass in noncardiac thoracic surgery - p. 431 32. Part V: Special situations for perfusion - p. 445 33. Chapter 29: Perfusion ethics, accreditation, and education - p. 445 34. Chapter 30: Perfusion training - p. 461 35. Chapter 31: Perfusion management - p. 469 36. Chapter 32: Adverse events and complications during cardiopulmonary bypass - p. 478 37. Chapter 33: Perfusion separation challenge - p. 499 38. Chapter 34: Perfusion for hyperthermic intraperitoneal chemotherapy by cardiopulmonary bypass machine - p. 510 39. Part VI: Miniaturizing cardiopulmonary bypass - p. 523 40. Chapter 35: Miniaturizing cardiopulmonary bypass - p. 523 41. Chapter 36: Minimally invasive extracorporeal circulation in cardiac surgery - p. 545 42. Chapter 37: Miniaturized cardiopulmonary bypass in heart valve surgery - p. 557 43. Chapter 38: MICPB in robotic cardiac surgery - p. 564 44. Chapter 39: Minimally invasive cardiopulmonary bypass in pediatrics - p. 574 45. Part VII: Organ injury and protection in cardiopulmonary bypass - p. 582 46. Chapter 40: The metabolic aspects of cardiopulmonary bypass - p. 582 47. Chapter 41: Inflammatory injury in cardiopulmonary bypass - p. 598 48. Chapter 42: Inflammatory protection and immune support for cardiopulmonary bypass - p. 613 49. Chapter 43: Lung injury in cardiopulmonary bypass - p. 623 50. Chapter 44: Pulmonary protection and respiratory support - p. 637 51. Chapter 45: Brain injury in cardiopulmonary bypass - p. 655 52. Chapter 46: Cerebral protection and neurological support - p. 669 53. Chapter 47: Kidney injury in cardiopulmonary bypass - p. 694 54. Chapter 48: Renal protection and nephritic support - p. 716 55. Chapter 49: Splanchnic protection and management in cardiopulmonary bypass - p. 737 56. Chapter 50: Intestinal protection and management in cardiopulmonary bypass - p. 749 57. Chapter 51: Endocrinological protection and management for cardiopulmonary bypass - p. 765 58. Chapter 52: Vessels’ injury in cardiopulmonary bypass - p. 774 59. Chapter 53: Infectional protection and antimicrobial support for cardiopulmonary bypass - p. 784 60. Volume II - p. 803 61. Part VIII: Extra corporeal membranous oxygenation (ECMO) - p. 803 62. Chapter 54: Extracorporeal membrane oxygenation - p. 803 63. Chapter 55: Extracorporeal membrane oxygenation contraindications - p. 831 64. Chapter 56: Hemodynamic evaluation of cannulas for ECMO - p. 843 65. Chapter 57: Electrocardiogram-synchronized pulsatility for ECMO - p. 864 66. Chapter 58: Cardiac protection and management during extracorporeal membrane oxygenation - p. 890 67. Chapter 59: Pulmonary protection and management during extracorporeal membrane oxygenation - p. 908 68. Chapter 60: Hemorraghic protection and management during extracorporeal membrane oxygenation - p. 923 69. Chapter 61: Cerebral protection and management during extracorporeal membrane oxygenation - p. 934 70. Chapter 62: Renal protection and management during extracorporeal membrane oxygenation - p. 946 71. Chapter 63: Gastrointestinal protection and management during extracorporeal membrane oxygenation - p. 962 72. Chapter 64: Vascular complications in extracorporeal membrane oxygenation - p. 968 73. Chapter 65: Infection protection and management during extracorporeal membrane oxygenation - p. 988 74. Chapter 66: Inflammatory protection and management during extracorporeal membrane oxygenation - p. 1000 75. Part IX: Special situations for ECMO - p. 1015 76. Chapter 67: Ethical challenges and quality assurance of extracorporeal membrane oxygenation - p. 1015 77. Chapter 68: Education and training for extracorporeal membrane oxygenation - p. 1030 78. Chapter 69: Nursing care of the patient on extracorporeal membrane oxygenation - p. 1038 79. Chapter 70: Transportation for ECMO - p. 1051 80. Chapter 71: Weaning strategies for ECMO and awake-ECMO - p. 1066 81. Part X: ECMO support in non-cardiac etiology - p. 1079 82. Chapter 72: Extracorporeal membrane oxygenation in neonates and infants - p. 1079 83. Chapter 73: Continuous renal replacement therapy during extracorporeal membrane oxygenation in neonates and infants - p. 1094 84. Chapter 74: Extracorporeal membrane oxygenation in nonsurgical lung conditions - p. 1115 85. Chapter 75: Lung surgery and extracorporeal membrane oxygenation - p. 1128 86. Chapter 76: Intracranial surgery and extracorporeal membrane oxygenation - p. 1146 87. Chapter 77: ECMO in controlled reperfusion of whole body (CARL) - p. 1170 88. Chapter 78: Extracorporeal life support in accidental hypothermia - p. 1183 89. Chapter 79: Extracorporeal membrane oxygenation in trauma - p. 1194 90. Chapter 80: Extracorporeal life support in pandemics - p. 1202 91. Chapter 81: ECMO in COVID–ARDS - p. 1212 92. Part XI: ECMO support in non-surgical cardiac etiology - p. 1229 93. Chapter 82: Extracorporeal membrane oxygenation for challenging percutaneous intervention - p. 1229 94. Chapter 83: Extracorporeal membrane oxygenation for end-stage heart failure - p. 1238 95. Chapter 84: Extracorporeal membrane oxygenation for cardiogenic shock - p. 1250 96. Chapter 85: ECMO for cardiopulmonary arrest (ECPR) - p. 1264 97. Part XII: ECMO support in surgical cardiac etiology - p. 1274 98. Chapter 86: Extracorporeal membrane oxygenation for postcardiotomy syndrome in adults - p. 1274 99. Chapter 87: ECMO for postcardiotomy syndrome in pediatric patients - p. 1288 100. Chapter 88: ECMO for post-LVAD right ventricular failure - p. 1297 101. Chapter 89: ECMO in thoracic transplantation - p. 1302 102. Part XIII: Non-ECMO artificial life support - p. 1326 103. Chapter 90: Non-extracorporeal membrane oxygenation artificial circulatory support devices - p. 1326 104. Chapter 91: Nonextracorporeal membrane oxygenation artificial respiratory support devices - p. 1345 105. Chapter 92: Non-extracorporeal membrane oxygenation artificial circulatory support for postcardiotomy syndrome - p. 1356 106. Chapter 93: Non-ECMO artificial circulatory support for percutaneous interventions - p. 1367 107. Chapter 94: Non-ECMO artificial life support for thoracic transplantation - p. 1378 108. Epilogue - p. 1390 109. Index - p. 1393
Cardiopulmonary Bypass: Advancements in Extracorporeal Life Support provides comprehensive coverage on the technological developments and clinical applications of extracorporeal technologies, including the underlying basic science and the latest clinical advances in the field. Written by experts around the world, this book comprises all characteristics of cardiopulmonary bypass as well as chapters regarding equipment, physiology and pathology, pediatric aspects and clinical applications. Important highlights include the latest updates regarding minimal invasive cardiopulmonary bypass (MICPB), extracorporeal circulatory and respiratory support (ECCRS) in cardiac and non-cardiac patients, ECMO support in COVID-19, and updated guidelines of extracorporeal technologies.
This book is an invaluable resource to clinicians, researchers and medical students in the fields of cardiothoracic surgery, cardiac anesthesiology, intensive care, and perfusion technology.
1. Chapter 1: Introduction to “surgical perspective” - p. lxxxi 2. Chapter 2: Introduction for “perfusional perspective” - p. 4 3. Part II: Artificial circulation and respiration - p. 6 4. Chapter 3: Development of artificial circulation - p. 6 5. Chapter 4: Future artificial surface physiology - p. 20 6. Chapter 5: Evolution of mechanical cardiac support - p. 31 7. Chapter 6: The future of artificial lung - p. 50 8. Chapter 7: Future noninvasive monitoring - p. 61 9. Chapter 8: Three-dimensional printing in cardiopulmonary disease - p. 79 10. Chapter 9: Guidelines for extracorporeal circulation - p. 103 11. Part III: Cardiopulmonary bypass (CPB) - p. 118 12. Chapter 10: Basics of extracorporeal circulation - p. 118 13. Chapter 11: Pathophysiology of cardiopulmonary bypass - p. 131 14. Chapter 12: Microcirculation during cardiopulmonary bypass - p. 151 15. Chapter 13: Perfusion standards and guidelines - p. 161 16. Chapter 14: Mechanical pumps for cardiopulmonary bypass - p. 178 17. Chapter 15: Oxygenators for extracorporeal circulation: theory and practice fundamentals for clinicians - p. 187 18. Chapter 16: Cannulations for cardiopulmonary bypass - p. 218 19. Chapter 17: Anesthesia during cardiopulmonary bypass - p. 234 20. Chapter 18: Monitoring during cardiopulmonary bypass - p. 254 21. Chapter 19: Transesophageal echocardiography and cardiopulmonary bypass - p. 282 22. Chapter 20: Hemostasis during cardiopulmonary bypass - p. 293 23. Chapter 21: Myocardial preservation during cardiopulmonary bypass - p. 307 24. Chapter 22: Cerebral preservation during deep hypothermic circulatory arrest in cardiopulmonary bypass - p. 325 25. Part IV: Special cardiopulmonary bypass - p. 338 26. Chapter 23: Cardiopulmonary bypass in pregnancy - p. 338 27. Chapter 24: Cardiopulmonary bypass in neonates and infants - p. 354 28. Chapter 25: Cardiopulmonary bypass in pediatrics - p. 376 29. Chapter 26: Cardiopulmonary bypass in thoracic aortic surgery - p. 392 30. Chapter 27: Cardiopulmonary bypass in lung transplantation - p. 416 31. Chapter 28: Cardiopulmonary bypass in noncardiac thoracic surgery - p. 431 32. Part V: Special situations for perfusion - p. 445 33. Chapter 29: Perfusion ethics, accreditation, and education - p. 445 34. Chapter 30: Perfusion training - p. 461 35. Chapter 31: Perfusion management - p. 469 36. Chapter 32: Adverse events and complications during cardiopulmonary bypass - p. 478 37. Chapter 33: Perfusion separation challenge - p. 499 38. Chapter 34: Perfusion for hyperthermic intraperitoneal chemotherapy by cardiopulmonary bypass machine - p. 510 39. Part VI: Miniaturizing cardiopulmonary bypass - p. 523 40. Chapter 35: Miniaturizing cardiopulmonary bypass - p. 523 41. Chapter 36: Minimally invasive extracorporeal circulation in cardiac surgery - p. 545 42. Chapter 37: Miniaturized cardiopulmonary bypass in heart valve surgery - p. 557 43. Chapter 38: MICPB in robotic cardiac surgery - p. 564 44. Chapter 39: Minimally invasive cardiopulmonary bypass in pediatrics - p. 574 45. Part VII: Organ injury and protection in cardiopulmonary bypass - p. 582 46. Chapter 40: The metabolic aspects of cardiopulmonary bypass - p. 582 47. Chapter 41: Inflammatory injury in cardiopulmonary bypass - p. 598 48. Chapter 42: Inflammatory protection and immune support for cardiopulmonary bypass - p. 613 49. Chapter 43: Lung injury in cardiopulmonary bypass - p. 623 50. Chapter 44: Pulmonary protection and respiratory support - p. 637 51. Chapter 45: Brain injury in cardiopulmonary bypass - p. 655 52. Chapter 46: Cerebral protection and neurological support - p. 669 53. Chapter 47: Kidney injury in cardiopulmonary bypass - p. 694 54. Chapter 48: Renal protection and nephritic support - p. 716 55. Chapter 49: Splanchnic protection and management in cardiopulmonary bypass - p. 737 56. Chapter 50: Intestinal protection and management in cardiopulmonary bypass - p. 749 57. Chapter 51: Endocrinological protection and management for cardiopulmonary bypass - p. 765 58. Chapter 52: Vessels’ injury in cardiopulmonary bypass - p. 774 59. Chapter 53: Infectional protection and antimicrobial support for cardiopulmonary bypass - p. 784 60. Volume II - p. 803 61. Part VIII: Extra corporeal membranous oxygenation (ECMO) - p. 803 62. Chapter 54: Extracorporeal membrane oxygenation - p. 803 63. Chapter 55: Extracorporeal membrane oxygenation contraindications - p. 831 64. Chapter 56: Hemodynamic evaluation of cannulas for ECMO - p. 843 65. Chapter 57: Electrocardiogram-synchronized pulsatility for ECMO - p. 864 66. Chapter 58: Cardiac protection and management during extracorporeal membrane oxygenation - p. 890 67. Chapter 59: Pulmonary protection and management during extracorporeal membrane oxygenation - p. 908 68. Chapter 60: Hemorraghic protection and management during extracorporeal membrane oxygenation - p. 923 69. Chapter 61: Cerebral protection and management during extracorporeal membrane oxygenation - p. 934 70. Chapter 62: Renal protection and management during extracorporeal membrane oxygenation - p. 946 71. Chapter 63: Gastrointestinal protection and management during extracorporeal membrane oxygenation - p. 962 72. Chapter 64: Vascular complications in extracorporeal membrane oxygenation - p. 968 73. Chapter 65: Infection protection and management during extracorporeal membrane oxygenation - p. 988 74. Chapter 66: Inflammatory protection and management during extracorporeal membrane oxygenation - p. 1000 75. Part IX: Special situations for ECMO - p. 1015 76. Chapter 67: Ethical challenges and quality assurance of extracorporeal membrane oxygenation - p. 1015 77. Chapter 68: Education and training for extracorporeal membrane oxygenation - p. 1030 78. Chapter 69: Nursing care of the patient on extracorporeal membrane oxygenation - p. 1038 79. Chapter 70: Transportation for ECMO - p. 1051 80. Chapter 71: Weaning strategies for ECMO and awake-ECMO - p. 1066 81. Part X: ECMO support in non-cardiac etiology - p. 1079 82. Chapter 72: Extracorporeal membrane oxygenation in neonates and infants - p. 1079 83. Chapter 73: Continuous renal replacement therapy during extracorporeal membrane oxygenation in neonates and infants - p. 1094 84. Chapter 74: Extracorporeal membrane oxygenation in nonsurgical lung conditions - p. 1115 85. Chapter 75: Lung surgery and extracorporeal membrane oxygenation - p. 1128 86. Chapter 76: Intracranial surgery and extracorporeal membrane oxygenation - p. 1146 87. Chapter 77: ECMO in controlled reperfusion of whole body (CARL) - p. 1170 88. Chapter 78: Extracorporeal life support in accidental hypothermia - p. 1183 89. Chapter 79: Extracorporeal membrane oxygenation in trauma - p. 1194 90. Chapter 80: Extracorporeal life support in pandemics - p. 1202 91. Chapter 81: ECMO in COVID–ARDS - p. 1212 92. Part XI: ECMO support in non-surgical cardiac etiology - p. 1229 93. Chapter 82: Extracorporeal membrane oxygenation for challenging percutaneous intervention - p. 1229 94. Chapter 83: Extracorporeal membrane oxygenation for end-stage heart failure - p. 1238 95. Chapter 84: Extracorporeal membrane oxygenation for cardiogenic shock - p. 1250 96. Chapter 85: ECMO for cardiopulmonary arrest (ECPR) - p. 1264 97. Part XII: ECMO support in surgical cardiac etiology - p. 1274 98. Chapter 86: Extracorporeal membrane oxygenation for postcardiotomy syndrome in adults - p. 1274 99. Chapter 87: ECMO for postcardiotomy syndrome in pediatric patients - p. 1288 100. Chapter 88: ECMO for post-LVAD right ventricular failure - p. 1297 101. Chapter 89: ECMO in thoracic transplantation - p. 1302 102. Part XIII: Non-ECMO artificial life support - p. 1326 103. Chapter 90: Non-extracorporeal membrane oxygenation artificial circulatory support devices - p. 1326 104. Chapter 91: Nonextracorporeal membrane oxygenation artificial respiratory support devices - p. 1345 105. Chapter 92: Non-extracorporeal membrane oxygenation artificial circulatory support for postcardiotomy syndrome - p. 1356 106. Chapter 93: Non-ECMO artificial circulatory support for percutaneous interventions - p. 1367 107. Chapter 94: Non-ECMO artificial life support for thoracic transplantation - p. 1378 108. Epilogue - p. 1390 109. Index - p. 1393
