Through ten outstanding editions, Cecil Essentials of Medicine has been a favorite of students, residents, and instructors for its concise, easy-to-read writing style and comprehensive coverage of this fast-changing field. The fully revised 11th Edition retains a focus on the high-yield, core knowledge of key importance for students on medicine rotation, residents, and practitioners who need quick access to a concise medical reference. Clinically focused and solidly grounded in basic science, it offers strong clinical content ideally suited for today’s more integrated programs.
1. Section I. Introduction to Medicine - p. S1 2. 1. Introduction to Medicine - p. 1 3. Section II. Cardiovascular Disease - p. S2 4. 2. Structure and Function of the Normal Heart and Blood Vessels - p. 3 5. 3. Evaluation of the Patient With Cardiovascular Disease - p. 11 6. 4. Diagnostic Tests and Procedures in the Patient With Cardiovascular Disease - p. 26 7. 5. Heart Failure and Cardiomyopathy - p. 47 8. 6. Congenital Heart Disease - p. 60 9. 7. Valvular Heart Disease - p. 69 10. 8. Coronary Heart Disease - p. 81 11. 9. Cardiac Arrhythmias - p. 102 12. 10. Pericardial and Myocardial Disease - p. 126 13. 11. Other Cardiac Topics - p. 135 14. 12. Vascular Diseases and Hypertension - p. 144 15. Section III. Pulmonary and Critical Care Medicine - p. S3 16. 13. Lung in Health and Disease - p. 167 17. 14. General Approach to Patients With Respiratory Disorders - p. 170 18. 15. Evaluating Lung Structure and Function - p. 174 19. 16. Obstructive Lung Diseases - p. 190 20. 17. Interstitial Lung Diseases - p. 203 21. 18. Pulmonary Vascular Diseases - p. 220 22. 19. Disorders of the Pleura, Mediastinum, and Chest Wall - p. 226 23. 20. Respiratory Failure - p. 232 24. 21. Transitions in Care From Pediatric to Adult Providers for Individuals With Pulmonary Disease - p. 239 25. Section IV. Preoperative and Postoperative Care - p. S4 26. 22. Preoperative and Postoperative Care - p. 246 27. Section V. Kidney Disease - p. S5 28. 23. Kidney Structure and Function - p. 257 29. 24. Approach to the Patient With Kidney Disease - p. 265 30. 25. Fluid and Electrolyte Disorders - p. 276 31. 26. Glomerular Diseases - p. 290 32. 27. Major Nonglomerular Disorders of the Kidney - p. 307 33. 28. Vascular Disorders of the Kidney - p. 321 34. 29. Acute Kidney Injury - p. 333 35. 30. Chronic Kidney Disease - p. 343 36. Section VI. Gastrointestinal Disease - p. S6 37. 31. Common Clinical Manifestations of Gastrointestinal Disease: Abdominal Pain - p. 352 38. 32. Common Clinical Manifestations of Gastrointestinal Disease: Gastrointestinal Hemorrhage - p. 355 39. 33. Common Clinical Manifestations of Gastrointestinal Disease: Malabsorption - p. 359 40. 34. Common Clinical Manifestations of Gastrointestinal Disease: Diarrhea - p. 366 41. 35. Endoscopic and Imaging Procedures - p. 371 42. 36. Esophageal Disorders - p. 379 43. 37. Diseases of the Stomach and Duodenum - p. 388 44. 38. Inflammatory Bowel Disease - p. 400 45. 39. Diseases of the Pancreas - p. 409 46. Section VII. Diseases of the Liver and Biliary System - p. S7 47. 40. Laboratory Tests in Liver Diseases - p. 425 48. 41. Jaundice - p. 428 49. 42. Acute and Chronic Hepatitis - p. 432 50. 43. Acute Liver Failure - p. 440 51. 44. Cirrhosis of the Liver and Its Complications - p. 443 52. 45. Disorders of the Gallbladder and Biliary Tract - p. 454 53. Section VIII. Hematologic Disease - p. S8 54. 46. Hematopoiesis and Hematopoietic Failure - p. 463 55. 47. Clonal Disorders of the Hematopoietic Stem Cell - p. 476 56. 48. Disorders of Red Blood Cells - p. 494 57. 49. Clinical Disorders of Granulocytes, Monocytes, and Macrophages - p. 506 58. 50. Disorders of Lymphocytes - p. 511 59. 51. Normal Hemostasis - p. 527 60. 52. Disorders of Hemostasis: Bleeding - p. 534 61. 53. Disorders of Hemostasis: Thrombosis - p. 554 62. Section IX. Oncologic Disease - p. S9 63. 54. Cancer Biology - p. 567 64. 55. Cancer Epidemiology - p. 577 65. 56. Principles of Cancer Therapy - p. 582 66. 57. Lung Cancer - p. 589 67. 58. Gastrointestinal Malignancies - p. 596 68. 59. Genitourinary Cancers - p. 602 69. 60. Breast Cancer - p. 609 70. 61. Gynecological Cancer - p. 615 71. 62. OtherSolidTumors(HeadandNeck, Sarcomas, Melanoma, Unknown Primary) - p. 623 72. 63. Complications of Cancer and Cancer Treatment - p. 628 73. Section X. Endocrine Disease and Metabolic Disease - p. S10 74. 64. Hypothalamic-Pituitary Axis - p. 634 75. 65. Thyroid Gland - p. 643 76. 66. Adrenal Gland - p. 653 77. 67. Male Reproductive Endocrinology - p. 665 78. 68. Diabetes Mellitus, Hypoglycemia - p. 670 79. 69. Obesity - p. 686 80. 70. Malnutrition, Nutritional Assessment, and Nutritional Support in Adult Patients - p. 694 81. 71. Disorders of Lipid Metabolism - p. 700 82. Section XI. Women’s, Men’s, and Transgender Health Topics - p. S11 83. 72. Women’s Health Topics - p. 709 84. 73. Men’s Health Topics - p. 724 85. 74. Transgender Medicine - p. 739 86. Section XII. Diseases of Bone and Bone Mineral Metabolism - p. S12 87. 75. Normal Physiology of Bone and Mineral Homeostasis - p. 747 88. 76. Disorders of Serum Minerals - p. 757 89. 77. Metabolic Bone Diseases - p. 766 90. 78. Osteoporosis - p. 775 91. Section XIII. Musculoskeletal and Connective Tissue Disease - p. S13 92. 79. Approach to the Patient With Rheumatic Disease - p. 785 93. 80. Rheumatoid Arthritis - p. 789 94. 81. Spondyloarthritis - p. 795 95. 82. Systemic Lupus Erythematosus - p. 800 96. 83. Systemic Sclerosis - p. 809 97. 84. Systemic Vasculitis - p. 816 98. 85. Crystal Arthropathies - p. 822 99. 86. Osteoarthritis - p. 828 100. 87. Nonarticular Soft Tissue Disorders - p. 831 101. 88. Rheumatic Manifestations of Systemic Disorders and Sjögren’s Syndrome - p. 835 102. Section XIV. Infectious Disease - p. S14 103. 89. Host Defenses Against Infection - p. 847 104. 90. Laboratory Diagnosis of Infectious Diseases - p. 857 105. 91. Fever and Febrile Syndromes - p. 864 106. 92. Bacteremia and Sepsis - p. 874 107. 93. Infections of the Central Nervous System - p. 881 108. 94. Head and Neck Infections - p. 898 109. 95. Infections of the Lower Respiratory Tract and COVID-19 - p. 904 110. 96. Infections of the Heart and Blood Vessels - p. 912 111. 97. Acute Bacterial Skin and Skin Structure Infections - p. 920 112. 98. Intra-abdominal Infections - p. 924 113. 99. Infectious Diarrhea - p. 931 114. 100. Infections Involving Bone and Joints - p. 937 115. 101. Urinary Tract Infections - p. 940 116. 102. Health Care–Associated Infections - p. 944 117. 103. Sexually Transmitted Infections - p. 950 118. 104. Human Immunodeficiency Virus Infection - p. 959 119. 105. Infections in the Immunocompromised Host - p. 978 120. 106. Infectious Diseases of Travelers: Protozoal and Helminthic Infections - p. 988 121. Section XV. Neurologic Disease - p. S15 122. 107. Neurologic Evaluation of the Patient - p. 996 123. 108. Disorders of Consciousness - p. 1002 124. 109. Disorders of Sleep - p. 1010 125. 110. Cortical Syndromes - p. 1015 126. 111. Dementia and Memory Disturbances - p. 1020 127. 112. Major Disorders of Mood, Thoughts, and Behavior - p. 1025 128. 113. Autonomic Nervous System Disorders - p. 1033 129. 114. Headache, Neck and Back Pain, and Cranial Neuralgias - p. 1036 130. 115. Disorders of Vision and Hearing - p. 1046 131. 116. Dizziness and Vertigo - p. 1055 132. 117. Disorders of the Motor System - p. 1058 133. 118. Congenital, Developmental, and Neurocutaneous Disorders - p. 1069 134. 119. Cerebrovascular Disease - p. 1077 135. 120. Traumatic Brain and Spinal Cord Injury - p. 1089 136. 121. Epilepsy - p. 1095 137. 122. Central Nervous System Tumors - p. 1109 138. 123. Demyelinating and Inflammatory Disorders - p. 1114 139. 124. Neuromuscular Diseases: Disorders of the Motor Neuron and Plexus and Peripheral Nerve Disease - p. 1124 140. 125. Muscle Diseases - p. 1135 141. 126. Neuromuscular Junction Disease - p. 1147 142. Section XVI. Geriatrics - p. S16 143. 127. The Aging Patient - p. 1151 144. Section XVII. Palliative Care - p. S17 145. 128. Palliative Care - p. 1163 146. Section XVIII. Alcohol and Substance Abuse - p. S18 147. 129. Alcohol and Substance Use - p. 1173 148. Index - p. 1190
Through ten outstanding editions, Cecil Essentials of Medicine has been a favorite of students, residents, and instructors for its concise, easy-to-read writing style and comprehensive coverage of this fast-changing field. The fully revised 11th Edition retains a focus on the high-yield, core knowledge of key importance for students on medicine rotation, residents, and practitioners who need quick access to a concise medical reference. Clinically focused and solidly grounded in basic science, it offers strong clinical content ideally suited for today’s more integrated programs.
1. Section I. Introduction to Medicine - p. S1 2. 1. Introduction to Medicine - p. 1 3. Section II. Cardiovascular Disease - p. S2 4. 2. Structure and Function of the Normal Heart and Blood Vessels - p. 3 5. 3. Evaluation of the Patient With Cardiovascular Disease - p. 11 6. 4. Diagnostic Tests and Procedures in the Patient With Cardiovascular Disease - p. 26 7. 5. Heart Failure and Cardiomyopathy - p. 47 8. 6. Congenital Heart Disease - p. 60 9. 7. Valvular Heart Disease - p. 69 10. 8. Coronary Heart Disease - p. 81 11. 9. Cardiac Arrhythmias - p. 102 12. 10. Pericardial and Myocardial Disease - p. 126 13. 11. Other Cardiac Topics - p. 135 14. 12. Vascular Diseases and Hypertension - p. 144 15. Section III. Pulmonary and Critical Care Medicine - p. S3 16. 13. Lung in Health and Disease - p. 167 17. 14. General Approach to Patients With Respiratory Disorders - p. 170 18. 15. Evaluating Lung Structure and Function - p. 174 19. 16. Obstructive Lung Diseases - p. 190 20. 17. Interstitial Lung Diseases - p. 203 21. 18. Pulmonary Vascular Diseases - p. 220 22. 19. Disorders of the Pleura, Mediastinum, and Chest Wall - p. 226 23. 20. Respiratory Failure - p. 232 24. 21. Transitions in Care From Pediatric to Adult Providers for Individuals With Pulmonary Disease - p. 239 25. Section IV. Preoperative and Postoperative Care - p. S4 26. 22. Preoperative and Postoperative Care - p. 246 27. Section V. Kidney Disease - p. S5 28. 23. Kidney Structure and Function - p. 257 29. 24. Approach to the Patient With Kidney Disease - p. 265 30. 25. Fluid and Electrolyte Disorders - p. 276 31. 26. Glomerular Diseases - p. 290 32. 27. Major Nonglomerular Disorders of the Kidney - p. 307 33. 28. Vascular Disorders of the Kidney - p. 321 34. 29. Acute Kidney Injury - p. 333 35. 30. Chronic Kidney Disease - p. 343 36. Section VI. Gastrointestinal Disease - p. S6 37. 31. Common Clinical Manifestations of Gastrointestinal Disease: Abdominal Pain - p. 352 38. 32. Common Clinical Manifestations of Gastrointestinal Disease: Gastrointestinal Hemorrhage - p. 355 39. 33. Common Clinical Manifestations of Gastrointestinal Disease: Malabsorption - p. 359 40. 34. Common Clinical Manifestations of Gastrointestinal Disease: Diarrhea - p. 366 41. 35. Endoscopic and Imaging Procedures - p. 371 42. 36. Esophageal Disorders - p. 379 43. 37. Diseases of the Stomach and Duodenum - p. 388 44. 38. Inflammatory Bowel Disease - p. 400 45. 39. Diseases of the Pancreas - p. 409 46. Section VII. Diseases of the Liver and Biliary System - p. S7 47. 40. Laboratory Tests in Liver Diseases - p. 425 48. 41. Jaundice - p. 428 49. 42. Acute and Chronic Hepatitis - p. 432 50. 43. Acute Liver Failure - p. 440 51. 44. Cirrhosis of the Liver and Its Complications - p. 443 52. 45. Disorders of the Gallbladder and Biliary Tract - p. 454 53. Section VIII. Hematologic Disease - p. S8 54. 46. Hematopoiesis and Hematopoietic Failure - p. 463 55. 47. Clonal Disorders of the Hematopoietic Stem Cell - p. 476 56. 48. Disorders of Red Blood Cells - p. 494 57. 49. Clinical Disorders of Granulocytes, Monocytes, and Macrophages - p. 506 58. 50. Disorders of Lymphocytes - p. 511 59. 51. Normal Hemostasis - p. 527 60. 52. Disorders of Hemostasis: Bleeding - p. 534 61. 53. Disorders of Hemostasis: Thrombosis - p. 554 62. Section IX. Oncologic Disease - p. S9 63. 54. Cancer Biology - p. 567 64. 55. Cancer Epidemiology - p. 577 65. 56. Principles of Cancer Therapy - p. 582 66. 57. Lung Cancer - p. 589 67. 58. Gastrointestinal Malignancies - p. 596 68. 59. Genitourinary Cancers - p. 602 69. 60. Breast Cancer - p. 609 70. 61. Gynecological Cancer - p. 615 71. 62. OtherSolidTumors(HeadandNeck, Sarcomas, Melanoma, Unknown Primary) - p. 623 72. 63. Complications of Cancer and Cancer Treatment - p. 628 73. Section X. Endocrine Disease and Metabolic Disease - p. S10 74. 64. Hypothalamic-Pituitary Axis - p. 634 75. 65. Thyroid Gland - p. 643 76. 66. Adrenal Gland - p. 653 77. 67. Male Reproductive Endocrinology - p. 665 78. 68. Diabetes Mellitus, Hypoglycemia - p. 670 79. 69. Obesity - p. 686 80. 70. Malnutrition, Nutritional Assessment, and Nutritional Support in Adult Patients - p. 694 81. 71. Disorders of Lipid Metabolism - p. 700 82. Section XI. Women’s, Men’s, and Transgender Health Topics - p. S11 83. 72. Women’s Health Topics - p. 709 84. 73. Men’s Health Topics - p. 724 85. 74. Transgender Medicine - p. 739 86. Section XII. Diseases of Bone and Bone Mineral Metabolism - p. S12 87. 75. Normal Physiology of Bone and Mineral Homeostasis - p. 747 88. 76. Disorders of Serum Minerals - p. 757 89. 77. Metabolic Bone Diseases - p. 766 90. 78. Osteoporosis - p. 775 91. Section XIII. Musculoskeletal and Connective Tissue Disease - p. S13 92. 79. Approach to the Patient With Rheumatic Disease - p. 785 93. 80. Rheumatoid Arthritis - p. 789 94. 81. Spondyloarthritis - p. 795 95. 82. Systemic Lupus Erythematosus - p. 800 96. 83. Systemic Sclerosis - p. 809 97. 84. Systemic Vasculitis - p. 816 98. 85. Crystal Arthropathies - p. 822 99. 86. Osteoarthritis - p. 828 100. 87. Nonarticular Soft Tissue Disorders - p. 831 101. 88. Rheumatic Manifestations of Systemic Disorders and Sjögren’s Syndrome - p. 835 102. Section XIV. Infectious Disease - p. S14 103. 89. Host Defenses Against Infection - p. 847 104. 90. Laboratory Diagnosis of Infectious Diseases - p. 857 105. 91. Fever and Febrile Syndromes - p. 864 106. 92. Bacteremia and Sepsis - p. 874 107. 93. Infections of the Central Nervous System - p. 881 108. 94. Head and Neck Infections - p. 898 109. 95. Infections of the Lower Respiratory Tract and COVID-19 - p. 904 110. 96. Infections of the Heart and Blood Vessels - p. 912 111. 97. Acute Bacterial Skin and Skin Structure Infections - p. 920 112. 98. Intra-abdominal Infections - p. 924 113. 99. Infectious Diarrhea - p. 931 114. 100. Infections Involving Bone and Joints - p. 937 115. 101. Urinary Tract Infections - p. 940 116. 102. Health Care–Associated Infections - p. 944 117. 103. Sexually Transmitted Infections - p. 950 118. 104. Human Immunodeficiency Virus Infection - p. 959 119. 105. Infections in the Immunocompromised Host - p. 978 120. 106. Infectious Diseases of Travelers: Protozoal and Helminthic Infections - p. 988 121. Section XV. Neurologic Disease - p. S15 122. 107. Neurologic Evaluation of the Patient - p. 996 123. 108. Disorders of Consciousness - p. 1002 124. 109. Disorders of Sleep - p. 1010 125. 110. Cortical Syndromes - p. 1015 126. 111. Dementia and Memory Disturbances - p. 1020 127. 112. Major Disorders of Mood, Thoughts, and Behavior - p. 1025 128. 113. Autonomic Nervous System Disorders - p. 1033 129. 114. Headache, Neck and Back Pain, and Cranial Neuralgias - p. 1036 130. 115. Disorders of Vision and Hearing - p. 1046 131. 116. Dizziness and Vertigo - p. 1055 132. 117. Disorders of the Motor System - p. 1058 133. 118. Congenital, Developmental, and Neurocutaneous Disorders - p. 1069 134. 119. Cerebrovascular Disease - p. 1077 135. 120. Traumatic Brain and Spinal Cord Injury - p. 1089 136. 121. Epilepsy - p. 1095 137. 122. Central Nervous System Tumors - p. 1109 138. 123. Demyelinating and Inflammatory Disorders - p. 1114 139. 124. Neuromuscular Diseases: Disorders of the Motor Neuron and Plexus and Peripheral Nerve Disease - p. 1124 140. 125. Muscle Diseases - p. 1135 141. 126. Neuromuscular Junction Disease - p. 1147 142. Section XVI. Geriatrics - p. S16 143. 127. The Aging Patient - p. 1151 144. Section XVII. Palliative Care - p. S17 145. 128. Palliative Care - p. 1163 146. Section XVIII. Alcohol and Substance Abuse - p. S18 147. 129. Alcohol and Substance Use - p. 1173 148. Index - p. 1190
