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Cerebellum Development and Disease, Volume 167 offers a comprehensive overview of the intricate processes underlying the formation, maturation, and function of the cerebellum, as well as the wide spectrum of disorders that can affect this essential brain region. Chapters in this new release cover Olivocerebellar circuit development as a substrate for dystonia pathogenesis, Simply complex – that structure of the cerebellar neuronal lineage, Ontogenesis and diversification of cerebellar glia: a developmental perspective, Purkinje cell diversification: a blueprint for cerebellar development, patterning, and evolution, On the Emergence of Folding in the Cerebellum, Scaling and regeneration in the developing cerebellum, ASTN2 in ASD and Neurodevelopmental Disorders, and much more.

Additional sections focus on Stem cell-derived in vitro models of human cerebellar development, Development of Spinocerebellar System within the Precerebellar Network, and Cerebellum evo-devo. The book brings together leading experts in neurodevelopment, neurobiology, genetics, and clinical neurosciences to explore the molecular and cellular mechanisms guiding cerebellar development, from embryogenesis to adulthood.

  • Covers the molecular, genetic, and cellular mechanisms underlying the development of the cerebellum from embryogenesis to adulthood
  • Bridges fundamental neurobiological insights with clinical perspectives on cerebellar disorders
  • Explores critical signaling pathways, transcription factors, and gene networks involved in cerebellar patterning, growth, and maturation

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Series Page - p. iii 6. Copyright - p. iv 7. Contributors - p. xiii 8. Chapter One: Simply complex – the structure of the cerebellar neuronal lineage - p. 1 9. Chapter Two: Purkinje cell diversification: A blueprint for cerebellar development, patterning, and evolution - p. 33 10. Chapter Three: Ontogenesis and diversification of cerebellar glia: A developmental perspective - p. 67 11. Chapter Four: On the emergence of folding in the cerebellum - p. 107 12. Chapter Five: Cerebellar nuclei output pathways regulate motor and non-motor behaviors through forebrain circuits - p. 135 13. Chapter Six: Development of the spinocerebellar system within the precerebellar network - p. 177 14. Chapter Seven: Evolutionary perspectives on the development of the mammalian cerebellum: From cellular diversity to gene regulatory programs - p. 229 15. Chapter Eight: Scaling and regeneration in the developing cerebellum - p. 267 16. Chapter Nine: Stem cell-derived in vitro models of human cerebellar development - p. 301 17. Chapter Ten: Lessons from human neuroimaging on the developing cerebellum in health and disease - p. 335 18. Chapter Eleven: Olivocerebellar circuit development as a substrate for dystonia pathogenesis - p. 379 19. Chapter Twelve: Developmental roots of cerebellar degeneration in spinocerebellar ataxia - p. 413 20. Chapter Thirteen: ASTN2 in ASD and neurodevelopmental disorders - p. 429

Descripcion
Descripción

Cerebellum Development and Disease, Volume 167 offers a comprehensive overview of the intricate processes underlying the formation, maturation, and function of the cerebellum, as well as the wide spectrum of disorders that can affect this essential brain region. Chapters in this new release cover Olivocerebellar circuit development as a substrate for dystonia pathogenesis, Simply complex – that structure of the cerebellar neuronal lineage, Ontogenesis and diversification of cerebellar glia: a developmental perspective, Purkinje cell diversification: a blueprint for cerebellar development, patterning, and evolution, On the Emergence of Folding in the Cerebellum, Scaling and regeneration in the developing cerebellum, ASTN2 in ASD and Neurodevelopmental Disorders, and much more.

Additional sections focus on Stem cell-derived in vitro models of human cerebellar development, Development of Spinocerebellar System within the Precerebellar Network, and Cerebellum evo-devo. The book brings together leading experts in neurodevelopment, neurobiology, genetics, and clinical neurosciences to explore the molecular and cellular mechanisms guiding cerebellar development, from embryogenesis to adulthood.

  • Covers the molecular, genetic, and cellular mechanisms underlying the development of the cerebellum from embryogenesis to adulthood
  • Bridges fundamental neurobiological insights with clinical perspectives on cerebellar disorders
  • Explores critical signaling pathways, transcription factors, and gene networks involved in cerebellar patterning, growth, and maturation

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Series Page - p. iii 6. Copyright - p. iv 7. Contributors - p. xiii 8. Chapter One: Simply complex – the structure of the cerebellar neuronal lineage - p. 1 9. Chapter Two: Purkinje cell diversification: A blueprint for cerebellar development, patterning, and evolution - p. 33 10. Chapter Three: Ontogenesis and diversification of cerebellar glia: A developmental perspective - p. 67 11. Chapter Four: On the emergence of folding in the cerebellum - p. 107 12. Chapter Five: Cerebellar nuclei output pathways regulate motor and non-motor behaviors through forebrain circuits - p. 135 13. Chapter Six: Development of the spinocerebellar system within the precerebellar network - p. 177 14. Chapter Seven: Evolutionary perspectives on the development of the mammalian cerebellum: From cellular diversity to gene regulatory programs - p. 229 15. Chapter Eight: Scaling and regeneration in the developing cerebellum - p. 267 16. Chapter Nine: Stem cell-derived in vitro models of human cerebellar development - p. 301 17. Chapter Ten: Lessons from human neuroimaging on the developing cerebellum in health and disease - p. 335 18. Chapter Eleven: Olivocerebellar circuit development as a substrate for dystonia pathogenesis - p. 379 19. Chapter Twelve: Developmental roots of cerebellar degeneration in spinocerebellar ataxia - p. 413 20. Chapter Thirteen: ASTN2 in ASD and neurodevelopmental disorders - p. 429

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