Chalcone is a highly versatile scaffold with a broad range of applications. Serving as a precursor for various organic molecules and natural flavonoids, it exhibits significant biological activities and unique physical properties, including semiconductor behavior, non-linear optical effects, fluorescence, and electronic characteristics. Chalcones have attracted considerable research interest due to their pharmacological potential and the ease with which their biological activity and other properties can be modified through subtle structural changes along the α,β-unsaturated backbone. Beyond their medicinal value, chalcones are utilized in the food and cosmetic industries as additives, owing to their UV-protective qualities. Additionally, they serve as chemosensors and probes in analytical applications. The book Chalcones and Their Derivatives: From Synthesis to Applications explores this remarkable molecule, detailing various synthetic methods, its biological significance, and its diverse applications across multiple fields. Serving as both a comprehensive reference for researchers and an essential guide for postgraduate students, this work provides valuable insights into the development and utilization of chalcone-based molecules for a wide array of purposes.
1. Cover image - p. c 2. Title page - p. i 3. Copyright - p. iv 4. Contents - p. v 5. Contributors - p. xiii 6. Preface - p. xvii 7. Chapter 1 Chalcone as a versatile scaffold: An overview - p. 1 8. Chapter 2 Naturally occurring chalcones and their biological activities - p. 19 9. Chapter 3 Chalcones in drug discovery and medicinal chemistry - p. 69 10. Chapter 4 Chalcones: Synthesis strategies and structural modifications - p. 125 11. Chapter 5 Exploring the anticancer potential of chalcones: Mechanistic insights and therapeutic prospects - p. 149 12. Chapter 6 Chalcones and their derivatives in food industry - p. 181 13. Chapter 7 Developing hybrid molecules from chalcones: Bridging structures for enhanced properties - p. 203 14. Chapter 8 Chalcone incorporating metal complexes and their biomedical applications - p. 227 15. Chapter 9 Chalcones: Structural modification in the synthesis of metal complexes and their applications - p. 251 16. Chapter 10 Chalcones and their derivatives as antioxidants: Mechanism and Applications - p. 293 17. Chapter 11 Chalcone hybrid molecules: Combining structures for enhanced properties - p. 325 18. Chapter 12 Chalcones in drug development: Synthesis, properties, and molecular docking insights into drug targets and biological activity - p. 347 19. Chapter 13 Chalcones as molecular probes in chemical biology and bioimaging - p. 371 20. Chapter 14 Photophysical behavior of chalcone derivatives: Insights and applications - p. 405 21. Chapter 15 Chalcone derivatives in photodynamic therapy: Illuminating new treatment approaches - p. 431 22. Chapter 16 The medicinal chemistry of chalcones as potential agents against neglected tropical diseases - p. 445 23. Chapter 17 Chalcones and their derivatives as anticancer agents: Mechanisms and applications - p. 489 24. Chapter 18 Exploring the antidiabetic potential of chalcones through modulation of PTP1B and PPARγ - p. 513 25. Chapter 19 Chalcone-based nanomaterials: Synthesis, characterization, and applications - p. 535 26. Chapter 20 Chalcones as fluorescence chemo-sensors for detection of metal ions - p. 557 27. Chapter 21 Chalcones as versatile probes for metal ion detection - p. 581 28. Chapter 22 Fluorometric and colorimetric sensor properties of chalcone derivatives for detection of metal ions by UV-spectra/emission spectra - p. 611 29. Chapter 23 Chalcone-based nanomaterials: Synthesis, characterization, and applications - p. 633 30. Chapter 24 Future perspective and emerging trends in chalcone research - p. 659 31. Index - p. 673
Chalcone is a highly versatile scaffold with a broad range of applications. Serving as a precursor for various organic molecules and natural flavonoids, it exhibits significant biological activities and unique physical properties, including semiconductor behavior, non-linear optical effects, fluorescence, and electronic characteristics. Chalcones have attracted considerable research interest due to their pharmacological potential and the ease with which their biological activity and other properties can be modified through subtle structural changes along the α,β-unsaturated backbone. Beyond their medicinal value, chalcones are utilized in the food and cosmetic industries as additives, owing to their UV-protective qualities. Additionally, they serve as chemosensors and probes in analytical applications. The book Chalcones and Their Derivatives: From Synthesis to Applications explores this remarkable molecule, detailing various synthetic methods, its biological significance, and its diverse applications across multiple fields. Serving as both a comprehensive reference for researchers and an essential guide for postgraduate students, this work provides valuable insights into the development and utilization of chalcone-based molecules for a wide array of purposes.
1. Cover image - p. c 2. Title page - p. i 3. Copyright - p. iv 4. Contents - p. v 5. Contributors - p. xiii 6. Preface - p. xvii 7. Chapter 1 Chalcone as a versatile scaffold: An overview - p. 1 8. Chapter 2 Naturally occurring chalcones and their biological activities - p. 19 9. Chapter 3 Chalcones in drug discovery and medicinal chemistry - p. 69 10. Chapter 4 Chalcones: Synthesis strategies and structural modifications - p. 125 11. Chapter 5 Exploring the anticancer potential of chalcones: Mechanistic insights and therapeutic prospects - p. 149 12. Chapter 6 Chalcones and their derivatives in food industry - p. 181 13. Chapter 7 Developing hybrid molecules from chalcones: Bridging structures for enhanced properties - p. 203 14. Chapter 8 Chalcone incorporating metal complexes and their biomedical applications - p. 227 15. Chapter 9 Chalcones: Structural modification in the synthesis of metal complexes and their applications - p. 251 16. Chapter 10 Chalcones and their derivatives as antioxidants: Mechanism and Applications - p. 293 17. Chapter 11 Chalcone hybrid molecules: Combining structures for enhanced properties - p. 325 18. Chapter 12 Chalcones in drug development: Synthesis, properties, and molecular docking insights into drug targets and biological activity - p. 347 19. Chapter 13 Chalcones as molecular probes in chemical biology and bioimaging - p. 371 20. Chapter 14 Photophysical behavior of chalcone derivatives: Insights and applications - p. 405 21. Chapter 15 Chalcone derivatives in photodynamic therapy: Illuminating new treatment approaches - p. 431 22. Chapter 16 The medicinal chemistry of chalcones as potential agents against neglected tropical diseases - p. 445 23. Chapter 17 Chalcones and their derivatives as anticancer agents: Mechanisms and applications - p. 489 24. Chapter 18 Exploring the antidiabetic potential of chalcones through modulation of PTP1B and PPARγ - p. 513 25. Chapter 19 Chalcone-based nanomaterials: Synthesis, characterization, and applications - p. 535 26. Chapter 20 Chalcones as fluorescence chemo-sensors for detection of metal ions - p. 557 27. Chapter 21 Chalcones as versatile probes for metal ion detection - p. 581 28. Chapter 22 Fluorometric and colorimetric sensor properties of chalcone derivatives for detection of metal ions by UV-spectra/emission spectra - p. 611 29. Chapter 23 Chalcone-based nanomaterials: Synthesis, characterization, and applications - p. 633 30. Chapter 24 Future perspective and emerging trends in chalcone research - p. 659 31. Index - p. 673
