Characterization of Polymeric Biomaterials presents a comprehensive introduction on the topic before discussing the morphology and surface characterization of biomedical polymers. The structural, mechanical, and biological characterization is described in detail, followed by invaluable case studies of polymer biomaterial implants.
With comprehensive coverage of both theoretical and experimental information, this title will provide scientists with an essential guide on the topic of these materials which are regularly used for clinical applications, such as implants and drug delivery devices. However, a range of novel polymers and the development and modification of existing medical polymers means that there is an ongoing need to satisfy particular design requirements. This book explains the critical and fundamentals methods to characterize polymer materials for biomedical applications.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. List of contributors - p. xi 6. Preface - p. xiii 7. Part One: Characterization of morphology of polymeric biomaterials - p. xiii 8. 1: Characterization of 2D polymeric biomaterial structures or surfaces - p. xiii 9. 2: Characterization of morphology—3D and porous structure - p. 19 10. Part Two: Surface characterization - p. 53 11. 3: Wettability and contact angle of polymeric biomaterials - p. 53 12. 4: X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (ToF SIMS) - p. 81 13. Part Three: Structure analysis - p. 97 14. 5: Molecular weight of polymers used in biomedical applications - p. 97 15. 6: Characterization of thermal properties and crystallinity of polymer biomaterials - p. 121 16. 7: NMR, FT-IR and raman characterization of biomaterials - p. 146 17. Part Four: Mechanical properties - p. 173 18. 8: Static and uniaxial characterization of polymer biomaterials - p. 173 19. 9: Dynamico-mechanical characterization of polymer biomaterials - p. 202 20. 10: Rheometry of polymeric biomaterials - p. 232 21. 11: Surface mechanical properties - p. 253 22. Part Five: Biological characterization - p. 282 23. 12: In vitro interaction of polymeric biomaterials with cells - p. 282 24. 13: Interaction of polymeric biomaterials with bacteria (static) - p. 315 25. 14: In vitro dynamic culture of cell-biomaterial constructs - p. 337 26. Part Six: Case studies - p. 363 27. 15: “Traditional” polymer medical devices: Ex vivo analysis - p. 363 28. 16: Collagen hydrogel-based scaffolds for vascular tissue regeneration: Mechanical and viscoelastic characterization - p. 396 29. 17: Polymer scaffolds for bone regeneration - p. 439 30. Index - p. 477
Characterization of Polymeric Biomaterials presents a comprehensive introduction on the topic before discussing the morphology and surface characterization of biomedical polymers. The structural, mechanical, and biological characterization is described in detail, followed by invaluable case studies of polymer biomaterial implants.
With comprehensive coverage of both theoretical and experimental information, this title will provide scientists with an essential guide on the topic of these materials which are regularly used for clinical applications, such as implants and drug delivery devices. However, a range of novel polymers and the development and modification of existing medical polymers means that there is an ongoing need to satisfy particular design requirements. This book explains the critical and fundamentals methods to characterize polymer materials for biomedical applications.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. List of contributors - p. xi 6. Preface - p. xiii 7. Part One: Characterization of morphology of polymeric biomaterials - p. xiii 8. 1: Characterization of 2D polymeric biomaterial structures or surfaces - p. xiii 9. 2: Characterization of morphology—3D and porous structure - p. 19 10. Part Two: Surface characterization - p. 53 11. 3: Wettability and contact angle of polymeric biomaterials - p. 53 12. 4: X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (ToF SIMS) - p. 81 13. Part Three: Structure analysis - p. 97 14. 5: Molecular weight of polymers used in biomedical applications - p. 97 15. 6: Characterization of thermal properties and crystallinity of polymer biomaterials - p. 121 16. 7: NMR, FT-IR and raman characterization of biomaterials - p. 146 17. Part Four: Mechanical properties - p. 173 18. 8: Static and uniaxial characterization of polymer biomaterials - p. 173 19. 9: Dynamico-mechanical characterization of polymer biomaterials - p. 202 20. 10: Rheometry of polymeric biomaterials - p. 232 21. 11: Surface mechanical properties - p. 253 22. Part Five: Biological characterization - p. 282 23. 12: In vitro interaction of polymeric biomaterials with cells - p. 282 24. 13: Interaction of polymeric biomaterials with bacteria (static) - p. 315 25. 14: In vitro dynamic culture of cell-biomaterial constructs - p. 337 26. Part Six: Case studies - p. 363 27. 15: “Traditional” polymer medical devices: Ex vivo analysis - p. 363 28. 16: Collagen hydrogel-based scaffolds for vascular tissue regeneration: Mechanical and viscoelastic characterization - p. 396 29. 17: Polymer scaffolds for bone regeneration - p. 439 30. Index - p. 477
