Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers thorough discussions on preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Chapter contributions from leading bioethicists and clinicians encourage a global, holistic perspective on applied challenges and the moral questions relating the implementation of genetic reproductive technology. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors and graduate and medical students.
As the Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy, this book presents a timely resource.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xiii 6. Chapter 1: Genomic Editing—From Human Health to the “Perfect Child” - p. xiv 7. Chapter 2: Ethics of Mitochondrial Gene Replacement Therapy - p. 30 8. Chapter 3: Reproductive Technologies Used by Same Gender Couples - p. 53 9. Chapter 4: Ethical Issues Raised by Multiparents - p. 79 10. Chapter 5: Revisiting the Nondirective Principle of Genetic Counseling in Prenatal Screening - p. 97 11. Chapter 6: Sex Selection, Gender Selection, and Sexism - p. 111 12. Chapter 7: The Impact of Big Data on Beginning of Life Issues - p. 130 13. Chapter 8: The Moral Status of the Embryo From the Standpoint of Social Perceptions - p. 147 14. Chapter 9: Fetal Reduction - p. 193 15. Chapter 10: Stem Cell Therapies for Neurodegenerative Disorders: An Ethical Analysis - p. 204 16. Chapter 11: Predictive Genetic Testing in Multifactorial Disorders - p. 228 17. Chapter 12: Whole-Genome Sequencing as a Method of Prenatal Genetic Diagnosis - p. 261 18. Chapter 13: Noninvasive Prenatal Genetic Diagnosis - p. 291 19. Chapter 14: Prenatal Testing in Low-Risk Populations: A US Perspective - p. 312 20. Chapter 15: Using Genetics for Enhancement (Liberal Eugenics) - p. 334 21. Chapter 16: Should Incidental Findings Arising From Prenatal Testing be Reported Indiscriminately to Patients? - p. 366 22. Chapter 17: Third Party Sharing of Genetic Information - p. 384 23. Index - p. 407
Clinical Ethics at the Crossroads of Genetic and Reproductive Technologies offers thorough discussions on preconception carrier screening, genetic engineering and the use of CRISPR gene editing, mitochondrial gene replacement therapy, sex selection, predictive testing, secondary findings, embryo reduction and the moral status of the embryo, genetic enhancement, and the sharing of genetic data. Chapter contributions from leading bioethicists and clinicians encourage a global, holistic perspective on applied challenges and the moral questions relating the implementation of genetic reproductive technology. The book is an ideal resource for practitioners, regulators, lawmakers, clinical researchers, genetic counselors and graduate and medical students.
As the Human Genome Project has triggered a technological revolution that has influenced nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, prenatal genetic testing, and gene therapy, this book presents a timely resource.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xiii 6. Chapter 1: Genomic Editing—From Human Health to the “Perfect Child” - p. xiv 7. Chapter 2: Ethics of Mitochondrial Gene Replacement Therapy - p. 30 8. Chapter 3: Reproductive Technologies Used by Same Gender Couples - p. 53 9. Chapter 4: Ethical Issues Raised by Multiparents - p. 79 10. Chapter 5: Revisiting the Nondirective Principle of Genetic Counseling in Prenatal Screening - p. 97 11. Chapter 6: Sex Selection, Gender Selection, and Sexism - p. 111 12. Chapter 7: The Impact of Big Data on Beginning of Life Issues - p. 130 13. Chapter 8: The Moral Status of the Embryo From the Standpoint of Social Perceptions - p. 147 14. Chapter 9: Fetal Reduction - p. 193 15. Chapter 10: Stem Cell Therapies for Neurodegenerative Disorders: An Ethical Analysis - p. 204 16. Chapter 11: Predictive Genetic Testing in Multifactorial Disorders - p. 228 17. Chapter 12: Whole-Genome Sequencing as a Method of Prenatal Genetic Diagnosis - p. 261 18. Chapter 13: Noninvasive Prenatal Genetic Diagnosis - p. 291 19. Chapter 14: Prenatal Testing in Low-Risk Populations: A US Perspective - p. 312 20. Chapter 15: Using Genetics for Enhancement (Liberal Eugenics) - p. 334 21. Chapter 16: Should Incidental Findings Arising From Prenatal Testing be Reported Indiscriminately to Patients? - p. 366 22. Chapter 17: Third Party Sharing of Genetic Information - p. 384 23. Index - p. 407
