Combination Drug Delivery Approach as an Effective Therapy for Various Diseases explores the use of bioengineering tools in combination drug delivery approaches to control various diseases at different clinical stages of synergistic action, varying mechanisms of action, and during the suppression of drug resistance. The book presents fundamental knowledge on the experiential and experimental aspects of drug combination approaches in order to equip rational applications in preventing the emergence of resistance during the treatment of various diseases. It provides a holistic understanding of the principles behind formation, characterization, applications, regulations, toxicity, challenges and future perspectives of combination drug delivery approaches.
It will be of interest to researchers and advanced graduate students in pharmaceutical science, chemistry, biology and medicine, as well as pharmaceutical companies and scientific organizations.
1. Combination Drug Delivery Approach as an Effective Therapy for Various Diseases - p. i 2. Cover - p. i 3. Title Page - p. i 4. Copyright Page - p. iv 5. Table of Contents - p. iv 6. Dedication - p. v 7. List of contributors - p. xv 8. Preface - p. xxi 9. Acknowledgments - p. xxiii 10. Chapter 1 Overcoming cancer drug resistance via nanomedicine-based combined drug delivery - p. 3 11. Chapter 2 Overcoming the challenges of drug resistance through combination drug delivery approach - p. 31 12. Chapter 3 Combination drug delivery approaches in ophthalmology - p. 47 13. Chapter 4 Combination drug delivery system to enhance the transdermal drug delivery of bioactive molecules - p. 65 14. Chapter 5 Combination drug delivery approaches in rheumatoid arthritis - p. 81 15. Chapter 6 Aptamer-mediated drug delivery system for cardiovascular diseases - p. 107 16. Chapter 7 Combination drug delivery approaches for viral infections - p. 129 17. Chapter 8 Approaches and molecular tools for targeted drug delivery in malaria infected red blood cells - p. 149 18. Chapter 9 Combination drug delivery approaches for tuberculosis - p. 173 19. Chapter 10 Combination drug delivery approaches for cancer therapy - p. 213 20. Chapter 11 Prodrug-based drug delivery approaches in cancer combination therapy - p. 239 21. Chapter 12 Combination of anticancer drugs with microRNA as cancer therapeutics - p. 273 22. Chapter 13 Nanotechnology-mediated combinational drug delivery approach for cancer therapy - p. 297 23. Chapter 14 Premarket review and postmarket regulation of combination drug products - p. 331 24. Chapter 15 Concluding remarks and future perspective of combination drug delivery systems - p. 353 25. Index - p. 397
Combination Drug Delivery Approach as an Effective Therapy for Various Diseases explores the use of bioengineering tools in combination drug delivery approaches to control various diseases at different clinical stages of synergistic action, varying mechanisms of action, and during the suppression of drug resistance. The book presents fundamental knowledge on the experiential and experimental aspects of drug combination approaches in order to equip rational applications in preventing the emergence of resistance during the treatment of various diseases. It provides a holistic understanding of the principles behind formation, characterization, applications, regulations, toxicity, challenges and future perspectives of combination drug delivery approaches.
It will be of interest to researchers and advanced graduate students in pharmaceutical science, chemistry, biology and medicine, as well as pharmaceutical companies and scientific organizations.
1. Combination Drug Delivery Approach as an Effective Therapy for Various Diseases - p. i 2. Cover - p. i 3. Title Page - p. i 4. Copyright Page - p. iv 5. Table of Contents - p. iv 6. Dedication - p. v 7. List of contributors - p. xv 8. Preface - p. xxi 9. Acknowledgments - p. xxiii 10. Chapter 1 Overcoming cancer drug resistance via nanomedicine-based combined drug delivery - p. 3 11. Chapter 2 Overcoming the challenges of drug resistance through combination drug delivery approach - p. 31 12. Chapter 3 Combination drug delivery approaches in ophthalmology - p. 47 13. Chapter 4 Combination drug delivery system to enhance the transdermal drug delivery of bioactive molecules - p. 65 14. Chapter 5 Combination drug delivery approaches in rheumatoid arthritis - p. 81 15. Chapter 6 Aptamer-mediated drug delivery system for cardiovascular diseases - p. 107 16. Chapter 7 Combination drug delivery approaches for viral infections - p. 129 17. Chapter 8 Approaches and molecular tools for targeted drug delivery in malaria infected red blood cells - p. 149 18. Chapter 9 Combination drug delivery approaches for tuberculosis - p. 173 19. Chapter 10 Combination drug delivery approaches for cancer therapy - p. 213 20. Chapter 11 Prodrug-based drug delivery approaches in cancer combination therapy - p. 239 21. Chapter 12 Combination of anticancer drugs with microRNA as cancer therapeutics - p. 273 22. Chapter 13 Nanotechnology-mediated combinational drug delivery approach for cancer therapy - p. 297 23. Chapter 14 Premarket review and postmarket regulation of combination drug products - p. 331 24. Chapter 15 Concluding remarks and future perspective of combination drug delivery systems - p. 353 25. Index - p. 397
