Concepts and Methodology in Cancer Diagnostics: An Immunological, Biochemical and Molecular Approach provides an exclusive combination of all basics and recent techniques, methodology, and advancements in the field of cancer diagnostics. With a strong focus on the procedures and techniques involved in cancer diagnostics, content also gives insights into the molecular tests required for different tumors for the administration of targeted drugs and precision medicine. In 11 chapters. The book also introduces the methods and technologies based on DNA and RNA based biomarkers, biochemical and immunological markers, genetic signatures, epigenetic changes and exosomes in blood, and tissue and body fluids. Readers will find a compilation of imperative topics and lists of the necessary materials and reagents needed, step-by-step instructions, readily reproducible laboratory protocols, as well as tips on troubleshooting and known pitfalls. This book is a valuable resource for medical professionals and researchers who want to understand the concepts of validated protocols and methodologies in diagnosing cancer, its prognosis, and predictive value.
1. Chapter One : Introduction to tumor diagnostic and prognostic: Differences between conventional and current approaches - p. Page ix 2. Chapter Two : Blood and other body fluid based biomarkers in tumor cells—Methods and protocol - p. Page 12 3. Chapter Three : Immunological markers in different cancers: L aboratory testing protocol and pitfalls - p. Page 29 4. Chapter Four : Cancer biomarkers based on liquid biopsies: Update and challenges - p. Page 39 5. Chapter Five : Oral salivary markers in different cancers: Current scenario in techniques and methodology - p. Page 60 6. Chapter six : Common childhood cancers: Diagnostic and prognosis markers - p. Page 74 7. Chapter seven : Oncometabolites in tumor cells: Current technique and procedure - p. Page 89 8. Chapter Eight : Immunohistochemistry based biomarkers in diagnosis of different types of tumor cells: Techniques, procedures and troubleshooting - p. Page 94 9. Chapter Nine : Currently available immunohistochemical marker for tumor prognosis and therapeutics - p. Page 113 10. Chapter Ten : Molecular markers based on targeted therapy in different tumors - p. Page 121 11. Chapter Eleven : Circulating tumor cell biomarkers and exosomal markers: Advances and laboratory approaches - p. Page 131 12. Index - p. Page 143
Concepts and Methodology in Cancer Diagnostics: An Immunological, Biochemical and Molecular Approach provides an exclusive combination of all basics and recent techniques, methodology, and advancements in the field of cancer diagnostics. With a strong focus on the procedures and techniques involved in cancer diagnostics, content also gives insights into the molecular tests required for different tumors for the administration of targeted drugs and precision medicine. In 11 chapters. The book also introduces the methods and technologies based on DNA and RNA based biomarkers, biochemical and immunological markers, genetic signatures, epigenetic changes and exosomes in blood, and tissue and body fluids. Readers will find a compilation of imperative topics and lists of the necessary materials and reagents needed, step-by-step instructions, readily reproducible laboratory protocols, as well as tips on troubleshooting and known pitfalls. This book is a valuable resource for medical professionals and researchers who want to understand the concepts of validated protocols and methodologies in diagnosing cancer, its prognosis, and predictive value.
1. Chapter One : Introduction to tumor diagnostic and prognostic: Differences between conventional and current approaches - p. Page ix 2. Chapter Two : Blood and other body fluid based biomarkers in tumor cells—Methods and protocol - p. Page 12 3. Chapter Three : Immunological markers in different cancers: L aboratory testing protocol and pitfalls - p. Page 29 4. Chapter Four : Cancer biomarkers based on liquid biopsies: Update and challenges - p. Page 39 5. Chapter Five : Oral salivary markers in different cancers: Current scenario in techniques and methodology - p. Page 60 6. Chapter six : Common childhood cancers: Diagnostic and prognosis markers - p. Page 74 7. Chapter seven : Oncometabolites in tumor cells: Current technique and procedure - p. Page 89 8. Chapter Eight : Immunohistochemistry based biomarkers in diagnosis of different types of tumor cells: Techniques, procedures and troubleshooting - p. Page 94 9. Chapter Nine : Currently available immunohistochemical marker for tumor prognosis and therapeutics - p. Page 113 10. Chapter Ten : Molecular markers based on targeted therapy in different tumors - p. Page 121 11. Chapter Eleven : Circulating tumor cell biomarkers and exosomal markers: Advances and laboratory approaches - p. Page 131 12. Index - p. Page 143
