Congenital Adrenal Hyperplasia: A Comprehensive Guide addresses how hydrocortisone works, what can go wrong, and how to correct it, also explaining why the timing of doses and measurement of cortisol from a dose is extremely important.
The book provides an in-depth analysis of this disorder for pediatric endocrinologists and primary care providers, allowing them to help patients with an updated model of care and appropriate treatment.
Patients and family members will benefit from the trend-forward information that will empower them to approach their healthcare providers with the expectation of receiving individualized care and treatment for this disorder.
1. Introduction - p. xxii 2. Section One: Congenital adrenal hyperplasia—introduction - p. xxv 3. Introduction - p. xxv 4. Chapter 1: Physiology of the Adrenal Glands: How Does It Work? - p. 1 5. Chapter 2: How Males and Females Develop - p. 17 6. Chapter 3: Genetics of Congenital Adrenal Hyperplasia - p. 29 7. Chapter 4: Common Forms of Congenital Adrenal Hyperplasia - p. 39 8. Chapter 5: Other Blocks in the Pathway Causing Congenital Adrenal Hyperplasia - p. 55 9. Chapter 6: Growth - p. 69 10. Chapter 7: Puberty - p. 81 11. Chapter 8: Biochemical Tests Used for Diagnosis - p. 94 12. Section Two: When things go wrong in congenital adrenal hyperplasia - p. 110 13. Introduction - p. 110 14. Chapter 9: Monitoring Long Term Outcomes - p. 111 15. Chapter 10: Growth - p. 119 16. Chapter 11: When Things Go Wrong With Puberty - p. 128 17. Chapter 12: When Things Go Wrong—Weight, Diabetes and Hypertension - p. 138 18. Chapter 13: When Things Go Wrong—Bone Density and Osteoporosis - p. 151 19. Chapter 14: Fertility - p. 159 20. Chapter 15: Sleep and Mood Alterations - p. 172 21. Chapter 16: Abdominal, Skin and Other Problems - p. 184 22. Section Three: Treatment for congenital adrenal hyperplasia - p. 195 23. Introduction - p. 195 24. Chapter 17: History of Steroid Development - p. 197 25. Chapter 18: Glucocorticoid Treatment - p. 210 26. Chapter 19: Glucose and Cortisol - p. 218 27. Chapter 20: Hydrocortisone - p. 230 28. Chapter 21: Dosing and the Circadian Rhythm - p. 249 29. Chapter 22: Cortisol and 17-Hydroxyprogesterone - p. 260 30. Chapter 23: Using Profiles to Assess Cortisol Replacement - p. 271 31. Chapter 24: Monitoring Hydrocortisone Therapy - p. 286 32. Chapter 25: Other Hormones and Their Roles - p. 307 33. Chapter 26: Missing a Dose of Hydrocortisone - p. 325 34. Chapter 27: Intravenous, Intramuscular and Other Forms of Hydrocortisone - p. 342 35. Chapter 28: The Pump Method for Achieving a Normal Circadian Cortisol Replacement - p. 351 36. Chapter 29: Stress Dosing for Sick Days, Surgery, Exams and Exercise - p. 378 37. Chapter 30: Practical Information Emergency Kit and School Information - p. 404 38. Chapter 31: Other Treatments for Congenital Adrenal Hyperplasia—Prednisolone, Dexamethasone and Adrenalectomy - p. 412 39. Chapter 32: Fludrocortisone 9 Alpha-Fludrocortisone - p. 421 40. Chapter 33: Travel and Time Zones - p. 430 41. Chapter 34: Thinking Through Blood Results–A Quiz - p. 436 42. Chapter 35: Discussing the Emotional Aspects of Living With Congenital Adrenal Hyperplasia - p. 454 43. Appendix 1: Converting System International (SI) Blood Measures Into North American Values or Conventional Units - p. 461 44. Appendix 2: List of Abbreviations - p. 463 45. Index - p. 465
Congenital Adrenal Hyperplasia: A Comprehensive Guide addresses how hydrocortisone works, what can go wrong, and how to correct it, also explaining why the timing of doses and measurement of cortisol from a dose is extremely important.
The book provides an in-depth analysis of this disorder for pediatric endocrinologists and primary care providers, allowing them to help patients with an updated model of care and appropriate treatment.
Patients and family members will benefit from the trend-forward information that will empower them to approach their healthcare providers with the expectation of receiving individualized care and treatment for this disorder.
1. Introduction - p. xxii 2. Section One: Congenital adrenal hyperplasia—introduction - p. xxv 3. Introduction - p. xxv 4. Chapter 1: Physiology of the Adrenal Glands: How Does It Work? - p. 1 5. Chapter 2: How Males and Females Develop - p. 17 6. Chapter 3: Genetics of Congenital Adrenal Hyperplasia - p. 29 7. Chapter 4: Common Forms of Congenital Adrenal Hyperplasia - p. 39 8. Chapter 5: Other Blocks in the Pathway Causing Congenital Adrenal Hyperplasia - p. 55 9. Chapter 6: Growth - p. 69 10. Chapter 7: Puberty - p. 81 11. Chapter 8: Biochemical Tests Used for Diagnosis - p. 94 12. Section Two: When things go wrong in congenital adrenal hyperplasia - p. 110 13. Introduction - p. 110 14. Chapter 9: Monitoring Long Term Outcomes - p. 111 15. Chapter 10: Growth - p. 119 16. Chapter 11: When Things Go Wrong With Puberty - p. 128 17. Chapter 12: When Things Go Wrong—Weight, Diabetes and Hypertension - p. 138 18. Chapter 13: When Things Go Wrong—Bone Density and Osteoporosis - p. 151 19. Chapter 14: Fertility - p. 159 20. Chapter 15: Sleep and Mood Alterations - p. 172 21. Chapter 16: Abdominal, Skin and Other Problems - p. 184 22. Section Three: Treatment for congenital adrenal hyperplasia - p. 195 23. Introduction - p. 195 24. Chapter 17: History of Steroid Development - p. 197 25. Chapter 18: Glucocorticoid Treatment - p. 210 26. Chapter 19: Glucose and Cortisol - p. 218 27. Chapter 20: Hydrocortisone - p. 230 28. Chapter 21: Dosing and the Circadian Rhythm - p. 249 29. Chapter 22: Cortisol and 17-Hydroxyprogesterone - p. 260 30. Chapter 23: Using Profiles to Assess Cortisol Replacement - p. 271 31. Chapter 24: Monitoring Hydrocortisone Therapy - p. 286 32. Chapter 25: Other Hormones and Their Roles - p. 307 33. Chapter 26: Missing a Dose of Hydrocortisone - p. 325 34. Chapter 27: Intravenous, Intramuscular and Other Forms of Hydrocortisone - p. 342 35. Chapter 28: The Pump Method for Achieving a Normal Circadian Cortisol Replacement - p. 351 36. Chapter 29: Stress Dosing for Sick Days, Surgery, Exams and Exercise - p. 378 37. Chapter 30: Practical Information Emergency Kit and School Information - p. 404 38. Chapter 31: Other Treatments for Congenital Adrenal Hyperplasia—Prednisolone, Dexamethasone and Adrenalectomy - p. 412 39. Chapter 32: Fludrocortisone 9 Alpha-Fludrocortisone - p. 421 40. Chapter 33: Travel and Time Zones - p. 430 41. Chapter 34: Thinking Through Blood Results–A Quiz - p. 436 42. Chapter 35: Discussing the Emotional Aspects of Living With Congenital Adrenal Hyperplasia - p. 454 43. Appendix 1: Converting System International (SI) Blood Measures Into North American Values or Conventional Units - p. 461 44. Appendix 2: List of Abbreviations - p. 463 45. Index - p. 465
