Congenital and Acquired Bone Marrow Failure is a comprehensive guide to congenital and acquired bone marrow failure in adult and pediatric patients. Chapters are divided into two sections, acquired aplastic anemia and inherited bone marrow failure syndromes. Content ranges from the basic, to the translational, and from the epidemiology of acquired aplastic anemia and telomere biology, to the management, treatment, and supportive care of pediatric, adult, and geriatric patients.
Contributors are world leading experts in the field of bone marrow failure. The book is required reading for residents, fellows, clinicians, and researchers across hematology, oncology, pathology, bone marrow transplantation, pediatrics, and internal medicine.
1. Introduction - p. x 2. Chapter 1: Epidemiology of Acquired Bone Marrow Failure - p. xii 3. Chapter 2: Pathophysiology of Acquired Bone Marrow Failure - p. 11 4. Chapter 3: Diagnosis of Acquired Aplastic Anemia - p. 33 5. Chapter 4: Acquired Overlap Bone Marrow Failure Disorders - p. 50 6. Chapter 5: Supportive Care in Aplastic Anemia - p. 56 7. Chapter 6: Immunosuppressive Therapy for Aplastic Anemia - p. 71 8. Chapter 7: Identical Sibling Donor Transplantation - p. 89 9. Chapter 8: Unrelated Donor Transplants for Acquired Aplastic Anemia - p. 99 10. Chapter 9: Umbilical Cord Blood Transplantation for Patients With Acquired and Inherited Bone Marrow Failure Syndromes on Behalf of Eurocord - p. 110 11. Chapter 10: Haploidentical Transplantation - p. 119 12. Chapter 11: Management of Acquired Aplastic Anemia in Children - p. 125 13. Chapter 12: Treatment of Elderly Patients With Aplastic Anemia - p. 139 14. Chapter 13: Emerging New Therapies for Acquired Bone Marrow Failure Disorders - p. 151 15. Chapter 14: Bone Marrow Failure in Paroxysmal Nocturnal Hemoglobinuria - p. 167 16. Chapter 15: Telomere Biology and Disease - p. 180 17. Chapter 16: Fanconi Anemia - p. 194 18. Chapter 17: Ribosomopathies and the Quality Control of Ribosome Assembly - p. 201 19. Chapter 18: Dyskeratosis Congenita - p. 224 20. Chapter 19: Amegakaryocytic Thrombocytopenia - p. 233 21. Chapter 20: Severe Congenital Neutropenias and Other Rare Inherited Disorders With Marrow Failure - p. 240 22. Chapter 21: Bone Marrow Failure Syndromes in Children - p. 253 23. Index - p. 267
Congenital and Acquired Bone Marrow Failure is a comprehensive guide to congenital and acquired bone marrow failure in adult and pediatric patients. Chapters are divided into two sections, acquired aplastic anemia and inherited bone marrow failure syndromes. Content ranges from the basic, to the translational, and from the epidemiology of acquired aplastic anemia and telomere biology, to the management, treatment, and supportive care of pediatric, adult, and geriatric patients.
Contributors are world leading experts in the field of bone marrow failure. The book is required reading for residents, fellows, clinicians, and researchers across hematology, oncology, pathology, bone marrow transplantation, pediatrics, and internal medicine.
1. Introduction - p. x 2. Chapter 1: Epidemiology of Acquired Bone Marrow Failure - p. xii 3. Chapter 2: Pathophysiology of Acquired Bone Marrow Failure - p. 11 4. Chapter 3: Diagnosis of Acquired Aplastic Anemia - p. 33 5. Chapter 4: Acquired Overlap Bone Marrow Failure Disorders - p. 50 6. Chapter 5: Supportive Care in Aplastic Anemia - p. 56 7. Chapter 6: Immunosuppressive Therapy for Aplastic Anemia - p. 71 8. Chapter 7: Identical Sibling Donor Transplantation - p. 89 9. Chapter 8: Unrelated Donor Transplants for Acquired Aplastic Anemia - p. 99 10. Chapter 9: Umbilical Cord Blood Transplantation for Patients With Acquired and Inherited Bone Marrow Failure Syndromes on Behalf of Eurocord - p. 110 11. Chapter 10: Haploidentical Transplantation - p. 119 12. Chapter 11: Management of Acquired Aplastic Anemia in Children - p. 125 13. Chapter 12: Treatment of Elderly Patients With Aplastic Anemia - p. 139 14. Chapter 13: Emerging New Therapies for Acquired Bone Marrow Failure Disorders - p. 151 15. Chapter 14: Bone Marrow Failure in Paroxysmal Nocturnal Hemoglobinuria - p. 167 16. Chapter 15: Telomere Biology and Disease - p. 180 17. Chapter 16: Fanconi Anemia - p. 194 18. Chapter 17: Ribosomopathies and the Quality Control of Ribosome Assembly - p. 201 19. Chapter 18: Dyskeratosis Congenita - p. 224 20. Chapter 19: Amegakaryocytic Thrombocytopenia - p. 233 21. Chapter 20: Severe Congenital Neutropenias and Other Rare Inherited Disorders With Marrow Failure - p. 240 22. Chapter 21: Bone Marrow Failure Syndromes in Children - p. 253 23. Index - p. 267
