Coronary Artery Disease: From Biology to Clinical Practice links the most important basic concepts of atherosclerosis pathophysiology to treatment management of coronary artery disease. Comprehensive coverage starts with the basic pathophysiologic mechanisms of the disease, including molecular and genetic mechanisms, cells interaction and inflammation. In addition, sections on novel anti-atherosclerotic therapies and a thorough understanding of the recent trends in clinical management round out this comprehensive tome that is ideal for practitioners and researchers.
By summarizing this novel knowledge and changes in diagnostic algorithm and treatment options, this is the perfect reference for cardiology researchers who want a volume with the most up-to-date experimental trends in the field of atherosclerosis, for cardiologists and physicians who manage patients with atherosclerotic risk factors and established coronary artery disease, and medical students who want to learn the basic concepts of atherosclerosis.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. xiii 6. Preface by Filippo Crea - p. xvii 7. Preface by Juan Carlos Kaski - p. xix 8. Preface by Emmanouil S. Brilakis - p. xxi 9. Chapter 1. Pathophysiology of Atherosclerosis - p. xxi 10. Chapter 1.1. Biology of the Vessel Wall - p. 3 11. Chapter 1.2. Endothelial Function - p. 13 12. Chapter 1.3. Atherosclerotic Plaque - p. 31 13. Chapter 1.4. Risk Factors of Atherosclerosis: Pathophysiological Mechanisms - p. 43 14. Chapter 1.5. The Role of Inflammation - p. 67 15. Chapter 1.6. The Role of Oxidative Stress - p. 95 16. Chapter 1.7. Genetics of Atherosclerosis - p. 101 17. Chapter 2. Coronary Artery Circulation: Basic Principles - p. 118 18. Chapter 2.1. Functional Anatomy - p. 121 19. Chapter 2.2. Myocardial Oxygen Consumption - p. 127 20. Chapter 2.3. Regulation of Oxygen Transport and Coronary Blood Flow - p. 137 21. Chapter 2.4. Stable Angina Pectoris - p. 157 22. Chapter 2.5. Acute Coronary Syndromes - p. 201 23. Chapter 3. Novel and Experimental Therapies in Advance Atherosclerosis - p. 233 24. Chapter 3.1. Anti-Inflammatory Treatment - p. 237 25. Chapter 3.2. Anti-Oxidant Treatment - p. 273 26. Chapter 3.3. Gene Therapy - p. 301 27. Chapter 3.4. Stem-Cell Therapy - p. 319 28. Chapter 3.5. Diagnostic Strategies-Novel Imaging Modalities-Multimodalities and Hybrid Techniques - p. 333 29. Chapter 3.5.1. Non-invasive Imaging Techniques in Coronary Artery Disease - p. 337 30. Chapter 3.5.2. Invasive Imaging Techniques - p. 359 31. Chapter 3.5.3. Functional Assessment of Coronary Lesions in the Cath Lab - p. 377 32. Chapter 3.6. Novel Antiplatelet Agents - p. 391 33. Chapter 3.7. Primary Percutaneous Coronary Intervention - p. 417 34. Chapter 3.8. Novel Developments in Interventional Strategies - p. 443 35. Index - p. 465
Coronary Artery Disease: From Biology to Clinical Practice links the most important basic concepts of atherosclerosis pathophysiology to treatment management of coronary artery disease. Comprehensive coverage starts with the basic pathophysiologic mechanisms of the disease, including molecular and genetic mechanisms, cells interaction and inflammation. In addition, sections on novel anti-atherosclerotic therapies and a thorough understanding of the recent trends in clinical management round out this comprehensive tome that is ideal for practitioners and researchers.
By summarizing this novel knowledge and changes in diagnostic algorithm and treatment options, this is the perfect reference for cardiology researchers who want a volume with the most up-to-date experimental trends in the field of atherosclerosis, for cardiologists and physicians who manage patients with atherosclerotic risk factors and established coronary artery disease, and medical students who want to learn the basic concepts of atherosclerosis.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Contributors - p. xiii 6. Preface by Filippo Crea - p. xvii 7. Preface by Juan Carlos Kaski - p. xix 8. Preface by Emmanouil S. Brilakis - p. xxi 9. Chapter 1. Pathophysiology of Atherosclerosis - p. xxi 10. Chapter 1.1. Biology of the Vessel Wall - p. 3 11. Chapter 1.2. Endothelial Function - p. 13 12. Chapter 1.3. Atherosclerotic Plaque - p. 31 13. Chapter 1.4. Risk Factors of Atherosclerosis: Pathophysiological Mechanisms - p. 43 14. Chapter 1.5. The Role of Inflammation - p. 67 15. Chapter 1.6. The Role of Oxidative Stress - p. 95 16. Chapter 1.7. Genetics of Atherosclerosis - p. 101 17. Chapter 2. Coronary Artery Circulation: Basic Principles - p. 118 18. Chapter 2.1. Functional Anatomy - p. 121 19. Chapter 2.2. Myocardial Oxygen Consumption - p. 127 20. Chapter 2.3. Regulation of Oxygen Transport and Coronary Blood Flow - p. 137 21. Chapter 2.4. Stable Angina Pectoris - p. 157 22. Chapter 2.5. Acute Coronary Syndromes - p. 201 23. Chapter 3. Novel and Experimental Therapies in Advance Atherosclerosis - p. 233 24. Chapter 3.1. Anti-Inflammatory Treatment - p. 237 25. Chapter 3.2. Anti-Oxidant Treatment - p. 273 26. Chapter 3.3. Gene Therapy - p. 301 27. Chapter 3.4. Stem-Cell Therapy - p. 319 28. Chapter 3.5. Diagnostic Strategies-Novel Imaging Modalities-Multimodalities and Hybrid Techniques - p. 333 29. Chapter 3.5.1. Non-invasive Imaging Techniques in Coronary Artery Disease - p. 337 30. Chapter 3.5.2. Invasive Imaging Techniques - p. 359 31. Chapter 3.5.3. Functional Assessment of Coronary Lesions in the Cath Lab - p. 377 32. Chapter 3.6. Novel Antiplatelet Agents - p. 391 33. Chapter 3.7. Primary Percutaneous Coronary Intervention - p. 417 34. Chapter 3.8. Novel Developments in Interventional Strategies - p. 443 35. Index - p. 465
