Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin is a comprehensive reference on techniques to enhance the bioavailability of curcumin, while also covering sustainability aspects across its production cycle. This book focuses on the information needs of pharmaceutical scientists aiming at developing drug delivery systems and formulations that can maximize the therapeutic impact of curcumin drugs. After an introduction to curcumin therapeutic properties, the authors delve into the bioavailability challenges confronted by curcumin, discussing influencing factors, pharmacokinetic pathways, and formulations to augment its bioaccessibility. Chapter 3 explores innovative formulation paradigms, encompassing nanoparticle-based delivery systems and lipidic matrices, tailored to overcome solubility limitations and increase absorptive efficacy. Chapter 4 covers delivery systems, encompassing prodrug strategies, encapsulation modalities, and nanocarrier technologies. Chapter 5 investigates sustainable sourcing and production, raising awareness to ethical cultivation practices, eco-friendly extraction methodologies, and proficient waste management techniques within curcumin production processes. In Chapter 6 discusses balancing bioavailability augmentation with sustainability principles including case studies. Chapter 7 navigates the domain of pharmacokinetic studies and clinical trials, providing an overview of bioaccessibility and bioavailable formulations. Chapter 8 explores safety profiles, regulatory requirements, and quality benchmarks, encompassing product labeling and claims concerning curcumin's bioavailability and sustainability. Chapter 9 casts a future view contemplating nascent technologies for bioavailability and sustainability optimization. The final chapter concludes the book with the author's observations on its central themes. Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin provides practical strategies to be explored by pharmaceutical scientists in increasing bioavailability of curcumin formulations. Research physicians and nutritionists may also benefit from the evidence-based information on curcumin's therapeutic activities provided across the book.
1. Chapter 1 Introduction to curcumin as a therapeutic agent - p. 1 2. Chapter 2 Bioavailability challenges of curcumin - p. 37 3. Chapter 3 Formulation approaches for enhancing curcumin bioavailability - p. 57 4. Chapter 4 Novel delivery systems for curcumin - p. 87 5. Chapter 5 Sustainable sourcing and production of curcumin - p. 121 6. Chapter 6 Bioavailability and sustainability considerations in formulation development - p. 153 7. Chapter 7 Pharmacokinetic studies and clinical trials - p. 181 8. Chapter 8 Safety and regulatory considerations - p. 213 9. Chapter 9 Future directions and challenges - p. 227 10. Chapter 10 Conclusion and closing remarks - p. 235 11. Index - p. 241
Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin is a comprehensive reference on techniques to enhance the bioavailability of curcumin, while also covering sustainability aspects across its production cycle. This book focuses on the information needs of pharmaceutical scientists aiming at developing drug delivery systems and formulations that can maximize the therapeutic impact of curcumin drugs. After an introduction to curcumin therapeutic properties, the authors delve into the bioavailability challenges confronted by curcumin, discussing influencing factors, pharmacokinetic pathways, and formulations to augment its bioaccessibility. Chapter 3 explores innovative formulation paradigms, encompassing nanoparticle-based delivery systems and lipidic matrices, tailored to overcome solubility limitations and increase absorptive efficacy. Chapter 4 covers delivery systems, encompassing prodrug strategies, encapsulation modalities, and nanocarrier technologies. Chapter 5 investigates sustainable sourcing and production, raising awareness to ethical cultivation practices, eco-friendly extraction methodologies, and proficient waste management techniques within curcumin production processes. In Chapter 6 discusses balancing bioavailability augmentation with sustainability principles including case studies. Chapter 7 navigates the domain of pharmacokinetic studies and clinical trials, providing an overview of bioaccessibility and bioavailable formulations. Chapter 8 explores safety profiles, regulatory requirements, and quality benchmarks, encompassing product labeling and claims concerning curcumin's bioavailability and sustainability. Chapter 9 casts a future view contemplating nascent technologies for bioavailability and sustainability optimization. The final chapter concludes the book with the author's observations on its central themes. Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin provides practical strategies to be explored by pharmaceutical scientists in increasing bioavailability of curcumin formulations. Research physicians and nutritionists may also benefit from the evidence-based information on curcumin's therapeutic activities provided across the book.
1. Chapter 1 Introduction to curcumin as a therapeutic agent - p. 1 2. Chapter 2 Bioavailability challenges of curcumin - p. 37 3. Chapter 3 Formulation approaches for enhancing curcumin bioavailability - p. 57 4. Chapter 4 Novel delivery systems for curcumin - p. 87 5. Chapter 5 Sustainable sourcing and production of curcumin - p. 121 6. Chapter 6 Bioavailability and sustainability considerations in formulation development - p. 153 7. Chapter 7 Pharmacokinetic studies and clinical trials - p. 181 8. Chapter 8 Safety and regulatory considerations - p. 213 9. Chapter 9 Future directions and challenges - p. 227 10. Chapter 10 Conclusion and closing remarks - p. 235 11. Index - p. 241
