Cell Transplantation and Gene Therapy in Neurodegenerative Disease, Volume 166 in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors who cover Challenges in translating a cell therapy to GMP, The challenges in developing a cell therapy for Huntington’s disease, Challenges of cell therapies for retinal diseases, Challenges of gene therapy in Huntington’s Disease, Technological advances and barriers to gene therapy, Considerations in the development of cell therapy modulation for spinal cord injury treatment, Challenges of developing glial cell therapy for ALS, and more.
Other chapters in this comprehensive release include Exploring cell and gene therapy in current animal models of Parkinson’s and Huntington’s disease, Considerations for the use of biomaterials to support cell therapy in degenerative disease, Neurosurgical challenges/innovations in cell and gene therapy delivery, Neuroimaging: the challenge of harnessing imaging tools to facilitate cell and gene therapy in neurodegenerative diseases/The contribution and challenges for imaging in advanced therapies of movement disorders, Considerations for clinical trial design for novel advanced therapeutics in neurodegenerative disease, and More than a trial participant: The role of the patient in ATMP development and trials for neurodegenerative disease.
1. 1 Introduction - p. 82 2. 2 Transplantation for spinal cord repair - p. 83 3. 3 Pro-regenerative transplants: Bridging for spinal cord repair - p. 92 4. 4 Building novel neuronal pathways: Neuronal relays for repair - p. 113 5. 5 Cell transplantation for neuroimmune modulation and neuroprotection - p. 124 6. 6 Considerations for contraindications and adverse effects - p. 127 7. 7 Closing remarks - p. 127 8. References - p. 129 9. Further reading - p. 158 10. Chapter Four: Investigating cell therapies in animal models of Parkinson's and Huntington's disease: Current challenges and considerations - p. 159 11. Chapter Five: Considerations for the use of biomaterials to support cell therapy in neurodegenerative disease - p. 191 12. Chapter Six: Challenges of translating a cell therapy to GMP - p. 207 13. Chapter Seven: Considerations for clinical trial design and conduct in the evaluation of novel advanced therapeutics in neurodegenerative disease - p. 235 14. Chapter Eight: More than a participant in trials of cell and gene therapy: Hearing the voices of people living with neurodegenerative diseases - p. 281
Cell Transplantation and Gene Therapy in Neurodegenerative Disease, Volume 166 in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors who cover Challenges in translating a cell therapy to GMP, The challenges in developing a cell therapy for Huntington’s disease, Challenges of cell therapies for retinal diseases, Challenges of gene therapy in Huntington’s Disease, Technological advances and barriers to gene therapy, Considerations in the development of cell therapy modulation for spinal cord injury treatment, Challenges of developing glial cell therapy for ALS, and more.
Other chapters in this comprehensive release include Exploring cell and gene therapy in current animal models of Parkinson’s and Huntington’s disease, Considerations for the use of biomaterials to support cell therapy in degenerative disease, Neurosurgical challenges/innovations in cell and gene therapy delivery, Neuroimaging: the challenge of harnessing imaging tools to facilitate cell and gene therapy in neurodegenerative diseases/The contribution and challenges for imaging in advanced therapies of movement disorders, Considerations for clinical trial design for novel advanced therapeutics in neurodegenerative disease, and More than a trial participant: The role of the patient in ATMP development and trials for neurodegenerative disease.
1. 1 Introduction - p. 82 2. 2 Transplantation for spinal cord repair - p. 83 3. 3 Pro-regenerative transplants: Bridging for spinal cord repair - p. 92 4. 4 Building novel neuronal pathways: Neuronal relays for repair - p. 113 5. 5 Cell transplantation for neuroimmune modulation and neuroprotection - p. 124 6. 6 Considerations for contraindications and adverse effects - p. 127 7. 7 Closing remarks - p. 127 8. References - p. 129 9. Further reading - p. 158 10. Chapter Four: Investigating cell therapies in animal models of Parkinson's and Huntington's disease: Current challenges and considerations - p. 159 11. Chapter Five: Considerations for the use of biomaterials to support cell therapy in neurodegenerative disease - p. 191 12. Chapter Six: Challenges of translating a cell therapy to GMP - p. 207 13. Chapter Seven: Considerations for clinical trial design and conduct in the evaluation of novel advanced therapeutics in neurodegenerative disease - p. 235 14. Chapter Eight: More than a participant in trials of cell and gene therapy: Hearing the voices of people living with neurodegenerative diseases - p. 281
