De novo Peptide Design: Principles and Applications presents the latest developments in the fields of therapeutic peptides and bio-nanotechnology. The title focuses on the design of peptides, particularly how peptides may be tailored to specific functions. It includes computational and experimental protocols to assist in the design of peptides. Sections cover the basics of protein and peptide structure, modeling and simulation, solid phase peptide synthesis, peptide-based antibiotics, drug delivery, peptide nanomaterials, aromatic interactions directing nano-assembly, protein/peptide aggregation, therapeutic interventions against protein/peptide aggregation diseases, peptide based hydrogels, computational tools and algorithms for peptide design, and experimental protocols in peptide chemistry.
In addition, the book covers key aspects in peptide design, providing a solution for researchers working within the 'peptidic universe' to create new therapeutic agents.
1. De Novo Peptide Design - p. i 2. Cover - p. i 3. Title Page - p. iii 4. Copyright Page - p. iv 5. Dedication - p. v 6. Table of Contents - p. vii 7. List of contributors - p. xiii 8. Chapter 1 Structural organization of peptides - p. 1 9. Chapter 2 Modeling and simulation of peptides - p. 35 10. Chapter 3 Solid phase peptide synthesis - p. 57 11. Chapter 4 Peptide-based Antibiotics - p. 79 12. Chapter 5 Cell-penetrating peptides - p. 105 13. Chapter 6 Peptide-based nanomaterials: applications and challenges - p. 133 14. Chapter 7 Peptide nanocatalysts - p. 173 15. Chapter 8 Bioinspired functional molecular constructs - p. 207 16. Chapter 9 Patents in peptide science - p. 255 17. Index - p. 277
De novo Peptide Design: Principles and Applications presents the latest developments in the fields of therapeutic peptides and bio-nanotechnology. The title focuses on the design of peptides, particularly how peptides may be tailored to specific functions. It includes computational and experimental protocols to assist in the design of peptides. Sections cover the basics of protein and peptide structure, modeling and simulation, solid phase peptide synthesis, peptide-based antibiotics, drug delivery, peptide nanomaterials, aromatic interactions directing nano-assembly, protein/peptide aggregation, therapeutic interventions against protein/peptide aggregation diseases, peptide based hydrogels, computational tools and algorithms for peptide design, and experimental protocols in peptide chemistry.
In addition, the book covers key aspects in peptide design, providing a solution for researchers working within the 'peptidic universe' to create new therapeutic agents.
1. De Novo Peptide Design - p. i 2. Cover - p. i 3. Title Page - p. iii 4. Copyright Page - p. iv 5. Dedication - p. v 6. Table of Contents - p. vii 7. List of contributors - p. xiii 8. Chapter 1 Structural organization of peptides - p. 1 9. Chapter 2 Modeling and simulation of peptides - p. 35 10. Chapter 3 Solid phase peptide synthesis - p. 57 11. Chapter 4 Peptide-based Antibiotics - p. 79 12. Chapter 5 Cell-penetrating peptides - p. 105 13. Chapter 6 Peptide-based nanomaterials: applications and challenges - p. 133 14. Chapter 7 Peptide nanocatalysts - p. 173 15. Chapter 8 Bioinspired functional molecular constructs - p. 207 16. Chapter 9 Patents in peptide science - p. 255 17. Index - p. 277
