Thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology, DeGroot’s Endocrinology, 8th Edition, remains the comprehensive, international reference of choice for today’s endocrinologists and fellows. A full peer review of the previous edition, conducted by a largely new group of renowned editors, was used to update this trusted, two-volume resource. In-depth coverage of both basic and clinical aspects of endocrinology and up-to-date information on the treatment and management of endocrine disorders are provided by a diverse group of expert contributors from six continents. A full-color format and helpful algorithms summarize clinical decision-making and practical approaches to patient management.
Organizes content by all the glands that regulate the endocrine system while integrating basic science and clinical presentations of disease.
Includes new chapters: Anatomy and Physiology of the Hypothalmus and Pituitary, Differentiated Thyroid Cancer, Medullary Thyroid Cancer, Drugs that Affect Thyroid Function, Genetic Disorders of the Adrenal Cortex, Adrenal Pathology, Primary Aldosteronism, Transgender Healthcare, Erectile Dysfunction, Prevalence and Causes of Male Infertility, Sexual Dysfunction in the Female, Glucose Toxicity and Oxidative Stress.
Emphasizes basic science and evidence-based practice throughout.
Features extensive updates to content on thyroid and adrenal disfunction, endocrine-disrupting chemicals and human disease, clinical management of diabetes, and advances in genetics.
Includes algorithms to outline effective treatment protocols.
Contains new emphasis boxes that highlight key points in each chapter.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. List of Tables - p. iii 8. Volume 1 - p. iii 9. Part 1: Principles of Endocrinology and Hormone Signaling - p. iii 10. Chapter 1: Principles of Endocrinology - p. iii 11. Chapter 2: Principles of Endocrine Measurements - p. g13 12. Chapter 3: Endocrine Rhythms, the Sleep-Wake Cycle, and Biological Clocks - p. g31 13. Part 2: Neuroendocrinology and Pituitary Disease - p. g42 14. Chapter 4: Prolactinomas and Disorders of Prolactin Secretion - p. g42 15. Chapter 5: Hypopituitarism Including Growth Hormone Deficiency - p. g62 16. Chapter 6: Acromegaly - p. g78 17. Chapter 7: Cushing Disease - p. g95 18. Chapter 8: Clinically Nonfunctioning Sellar Masses - p. g128 19. Chapter 9: Thyroid-Stimulating Hormone–Producing Pituitary Tumors - p. g142 20. Chapter 10: Pituitary Surgery - p. g153 21. Chapter 11: Craniopharyngiomas and Parasellar Masses - p. g167 22. Chapter 12: Disorders of Sodium, Diabetes Insipidus and Hyponatremia - p. g178 23. Chapter 13: Anatomy and Physiology of the Hypothalamus and Pituitary - p. g196 24. Chapter 14: Genetic Disorders of the Pituitary - p. g210 25. Chapter 15: Aggressive Pituitary Tumors - p. g221 26. Chapter 16: Radiotherapy in Pituitary Tumors - p. g233 27. Chapter 17: Somatic Growth and Maturation: Growth Hormone and Other Growth Factors - p. g246 28. Chapter 18: Growth Hormone Deficiency in Children - p. g273 29. Part 3: Obesity and Nutrition - p. g300 30. Chapter 19: Basic and Clinical Appetite Regulation and Energy Expenditure - p. g300 31. Chapter 20: Obesity: Risk, Risk Factors, and Medical Management - p. g318 32. Chapter 21: Genetic Syndromes Associated With Obesity - p. g330 33. Chapter 22: Regulation of Intermediary Metabolism During Fasting, Feeding, and Exercise - p. g340 34. Chapter 23: Adipose Tissue Function: Metabolic and Endocrine - p. g360 35. Chapter 24: Lipodystrophy Syndromes - p. g376 36. Chapter 25: Lipoprotein Metabolism and the Treatment of Lipid Disorders - p. g395 37. Chapter 26: Metabolic Syndrome - p. g420 38. Chapter 27: Bariatric Procedures and Operations - p. g443 39. Part 4: Diabetes Mellitus - p. g467 40. Chapter 28: Development of the Endocrine Pancreas - p. g467 41. Chapter 29: Regulation of Islet Hormone Synthesis and Secretion - p. g482 42. Chapter 30: Mechanisms of Insulin Action - p. g495 43. Chapter 31: Classification and Diagnosis of Diabetes Mellitus - p. g516 44. Chapter 32: Autoimmune (Type 1) Diabetes Mellitus: Etiology, Pathogenesis, Prediction, and Prevention - p. g534 45. Chapter 33: Type 2 Diabetes Mellitus: Etiology, Pathogenesis, and Natural History - p. g551 46. Chapter 34: Diabetes Mellitus and Pregnancy - p. g551 47. Chapter 35: Hyperglycemia Secondary to Non-Traditional Diabetic Conditions - p. g605 48. Chapter 36: β Cell Glucose Toxicity and Oxidative Stress - p. g627 49. Chapter 37: Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State - p. g638 50. Chapter 38: Hypoglycemia and Hypoglycemic Syndromes - p. g650 51. Chapter 39: Treatment of Type 1 Diabetes Mellitus in Adults - p. g650 52. Chapter 40: Clinical Management of Type 2 Diabetes Mellitus - p. g686 53. Chapter 41: Pancreas and Islet Transplantation - p. g686 54. Chapter 42: Diabetes and Long-Term Complications - p. g724 55. Chapter 43: Diabetic Eye Disease - p. g738 56. Chapter 44: Diabetic Neuropathy - p. g752 57. Chapter 45: Diabetic Kidney Disease - p. g767 58. Chapter 46: Diabetic Foot and Vascular Complications - p. g785 59. Part 5: Parathyroid Gland, Calciotropic Hormones, and Bone Metabolism - p. g798 60. Chapter 47: Parathyroid Hormone and the Parathyroid Hormone Receptor Type 1 in the Regulation of Calcium and Phosphate Homeostasis and Bone Metabolism - p. g798 61. Chapter 48: Parathyroid Hormone-Related Protein - p. g816 62. Chapter 49: Calcitonin - p. g831 63. Chapter 50: Vitamin D: From Photosynthesis, Metabolism, and Action to Clinical Applications - p. g846 64. Chapter 51: Bone Development and Remodeling - p. g866 65. Chapter 52: Regulation of Calcium Homeostasis and Genetic Disorders That Affect Calcium Metabolism - p. g886 66. Chapter 53: Genetic Disorders of Phosphate Homeostasis - p. g905 67. Chapter 54: Primary Hyperparathyroidism - p. g919 68. Chapter 55: Malignancy-Associated Hypercalcemia - p. g939 69. Chapter 56: Surgical Management of Hyperparathyroidism - p. g951 70. Chapter 57: Pseudohypoparathyroidism, Albright’s Hereditary Osteodystrophy, and Progressive Osseous Heteroplasia: Disorders Caused byGNAS Mutations That Reduce Gsα Activity - p. g970 71. Chapter 58: Genetic Defects in Vitamin D Metabolism and Action - p. g986 72. Chapter 59: Hereditary Disorders of the Skeleton - p. g1004 73. Chapter 60: Osteoporosis - p. g1019 74. Chapter 61: CKD-MBD Syndrome: Chronic Kidney Disease Produced Disorders in Skeletal, Vascular, and Cardiac Tissues and Mineral Metabolism - p. g1037 75. Chapter 62: Disorders of Mineralization - p. g1037 76. Chapter 63: Paget Disease of Bone - p. g1063 77. Volume 2 - p. g1075 78. Part 6: Thyroid - p. g1075 79. Chapter 64: Anatomy and Development of the Thyroid - p. g1075 80. Chapter 65: Thyroid-Stimulating Hormone and TSH Receptor - p. g1075 81. Chapter 66: Thyroid Hormone Transporters and Metabolism - p. g1075 82. Chapter 67: Thyroid Hormone Action - p. g1125 83. Chapter 68: Thyroid Function Testing (Thyrotropin, Triiodothyronine, and Thyroxine) - p. g1139 84. Chapter 69: Thyroid Imaging - p. g1149 85. Chapter 70: Pathology of the Thyroid Gland - p. g1163 86. Chapter 71: Graves Disease - p. g1174 87. Chapter 72: Graves’ Orbitopathy - p. g1190 88. Chapter 73: Thyroiditis - p. g1211 89. Chapter 74: Hypothyroidism - p. g1231 90. Chapter 75: Thyroid and Pregnancy - p. g1248 91. Chapter 76: Iodine Nutrition and the Thyroid - p. g1263 92. Chapter 77: Euthyroid and Hyperthyroid Nodules and Goiter - p. g1274 93. Chapter 78: Differentiated Thyroid Cancer – Streamlining Diagnosis And Optimizing Management - p. g1294 94. Chapter 79: Medullary Thyroid Cancer - p. g1312 95. Chapter 80: Anaplastic (Undifferentiated) Thyroid Carcinoma - p. g1324 96. Chapter 81: Resistance to Thyroid Hormone and Genetic Defects of the Thyroid - p. g1335 97. Chapter 82: Surgical Management of Thyroid Disease - p. g1354 98. Chapter 83: Nonthyroidal Illness Syndrome - p. g1372 99. Chapter 84: Drugs and Thyroid - p. g1385 100. Part 7: Adrenal - p. g1404 101. Chapter 85: Adrenal Development and Homeostasis - p. g1404 102. Chapter 86: Genetic Disorders of the Adrenal Cortex - p. g1424 103. Chapter 87: Enzymes and Pathways of Human Steroidogenesis - p. g1443 104. Chapter 88: Mineralocorticoids: Physiology, Metabolism, Receptors, and Resistance - p. g1469 105. Chapter 89: Glucocorticoid Receptors: Mechanisms of Action in Health and Disease - p. g1481 106. Chapter 90: Adrenal Androgens, Adrenarche, and Adrenopause - p. g1493 107. Chapter 91: Adrenal Pathology - p. g1505 108. Chapter 92: Adrenal Gland Imaging - p. g1527 109. Chapter 93: Adrenal Insufficiency - p. g1548 110. Chapter 94: Defects of Adrenal Steroidogenesis - p. g1565 111. Chapter 95: Adrenal Genomics II: Familial and Sporadic Neoplasia - p. g1586 112. Chapter 96: Primary Aldosteronism - p. g1597 113. Chapter 97: Adrenocorticotropic Hormone–Independent Cushing Syndrome - p. g1610 114. Chapter 98: Adrenocortical Carcinoma - p. g1628 115. Chapter 99: Pheochromocytoma - p. g1639 116. Chapter 100: Adrenal Surgery - p. g1657 117. Part 8: Reproductive Endocrinology and Sexual Function - p. g1681 118. Chapter 101: Differences of Sex Development - p. g1681 119. Chapter 102: Endocrinology of Sexual Maturation and Puberty - p. g1712 120. Chapter 103: Endocrinology of Pubertal Disorders - p. g1728 121. Chapter 104: Transgender Healthcare - p. g1748 122. Part 9: Male Reproduction - p. g1756 123. Chapter 105: Gonadotropin Regulation and Androgen and Estrogen Physiology - p. g1756 124. Chapter 106: Hypogonadism: Pathogenesis, Diagnosis, and Treatment - p. g1777 125. Chapter 107: Testosterone Deficiency: Aging and Chronic Disease - p. g1801 126. Chapter 108: Gynecomastia - p. g1809 127. Chapter 109: Erectile Dysfunction - p. g1809 128. Chapter 110: Misuse and Abuse of Anabolic Hormones - p. g1842 129. Chapter 111: Regulation of Spermatogenesis - p. g1857 130. Chapter 112: Prevalence and Causes of Male Infertility - p. g1874 131. Chapter 113: Clinical Management of Male Infertility - p. g1888 132. Chapter 114: Male Contraception - p. g1903 133. Chapter 115: Testicular Dysgenesis Syndrome and Testicular Tumors - p. g1915 134. Chapter 116: Benign Prostatic Hyperplasia and Prostate Cancer - p. g1932 135. Part 10: Female Reproduction - p. g1946 136. Chapter 117: The Menstrual Cycle and Disorders of Ovulation - p. g1946 137. Chapter 118: Folliculogenesis, Ovulation, and Luteogenesis - p. g1968 138. Chapter 119: Ovarian Hormone Synthesis - p. g1984 139. Chapter 120: Estrogen and Progesterone Action - p. g2000 140. Chapter 121: Contraception - p. g2017 141. Chapter 122: Menopause and Perimenopause - p. g2027 142. Chapter 123: Female Infertility: Evaluation and Management - p. g2042 143. Chapter 124: Androgen Excess Disorders in Women - p. g2057 144. Chapter 125: Endometriosis - p. g2076 145. Chapter 126: Uterine Fibroids and Adenomyosis - p. g2089 146. Chapter 127: Hormonal Control of the Breast - p. g2101 147. Chapter 128: Sexual Dysfunction in the Female - p. g2120 148. Chapter 129: Hormonal Control of Human Pregnancy and Parturition - p. g2132 149. Chapter 130: Fetal and Neonatal Endocrinology - p. g2147 150. Chapter 131: Hormonal Changes and Pregnancy Testing - p. g2186 151. Part 11: Multisystem Endocrine Disorders - p. g2215 152. Chapter 132: Autoimmune Polyglandular Syndromes - p. g2215 153. Chapter 133: Multiple Endocrine Neoplasia Type 1 - p. g2234 154. Chapter 134: Multiple Endocrine Neoplasia Types 2 and 3, and Medullary Thyroid Carcinoma - p. g2253 155. Chapter 135: Neuroendocrine Tumor Syndromes - p. g2270 156. Chapter 136: Ectopic Hormone Syndromes - p. g2287 157. Chapter 137: Endocrine-Disrupting Chemicals and Human Health - p. g2300 158. Index - p. g2318
Thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology, DeGroot’s Endocrinology, 8th Edition, remains the comprehensive, international reference of choice for today’s endocrinologists and fellows. A full peer review of the previous edition, conducted by a largely new group of renowned editors, was used to update this trusted, two-volume resource. In-depth coverage of both basic and clinical aspects of endocrinology and up-to-date information on the treatment and management of endocrine disorders are provided by a diverse group of expert contributors from six continents. A full-color format and helpful algorithms summarize clinical decision-making and practical approaches to patient management.
Organizes content by all the glands that regulate the endocrine system while integrating basic science and clinical presentations of disease.
Includes new chapters: Anatomy and Physiology of the Hypothalmus and Pituitary, Differentiated Thyroid Cancer, Medullary Thyroid Cancer, Drugs that Affect Thyroid Function, Genetic Disorders of the Adrenal Cortex, Adrenal Pathology, Primary Aldosteronism, Transgender Healthcare, Erectile Dysfunction, Prevalence and Causes of Male Infertility, Sexual Dysfunction in the Female, Glucose Toxicity and Oxidative Stress.
Emphasizes basic science and evidence-based practice throughout.
Features extensive updates to content on thyroid and adrenal disfunction, endocrine-disrupting chemicals and human disease, clinical management of diabetes, and advances in genetics.
Includes algorithms to outline effective treatment protocols.
Contains new emphasis boxes that highlight key points in each chapter.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. iii 7. List of Tables - p. iii 8. Volume 1 - p. iii 9. Part 1: Principles of Endocrinology and Hormone Signaling - p. iii 10. Chapter 1: Principles of Endocrinology - p. iii 11. Chapter 2: Principles of Endocrine Measurements - p. g13 12. Chapter 3: Endocrine Rhythms, the Sleep-Wake Cycle, and Biological Clocks - p. g31 13. Part 2: Neuroendocrinology and Pituitary Disease - p. g42 14. Chapter 4: Prolactinomas and Disorders of Prolactin Secretion - p. g42 15. Chapter 5: Hypopituitarism Including Growth Hormone Deficiency - p. g62 16. Chapter 6: Acromegaly - p. g78 17. Chapter 7: Cushing Disease - p. g95 18. Chapter 8: Clinically Nonfunctioning Sellar Masses - p. g128 19. Chapter 9: Thyroid-Stimulating Hormone–Producing Pituitary Tumors - p. g142 20. Chapter 10: Pituitary Surgery - p. g153 21. Chapter 11: Craniopharyngiomas and Parasellar Masses - p. g167 22. Chapter 12: Disorders of Sodium, Diabetes Insipidus and Hyponatremia - p. g178 23. Chapter 13: Anatomy and Physiology of the Hypothalamus and Pituitary - p. g196 24. Chapter 14: Genetic Disorders of the Pituitary - p. g210 25. Chapter 15: Aggressive Pituitary Tumors - p. g221 26. Chapter 16: Radiotherapy in Pituitary Tumors - p. g233 27. Chapter 17: Somatic Growth and Maturation: Growth Hormone and Other Growth Factors - p. g246 28. Chapter 18: Growth Hormone Deficiency in Children - p. g273 29. Part 3: Obesity and Nutrition - p. g300 30. Chapter 19: Basic and Clinical Appetite Regulation and Energy Expenditure - p. g300 31. Chapter 20: Obesity: Risk, Risk Factors, and Medical Management - p. g318 32. Chapter 21: Genetic Syndromes Associated With Obesity - p. g330 33. Chapter 22: Regulation of Intermediary Metabolism During Fasting, Feeding, and Exercise - p. g340 34. Chapter 23: Adipose Tissue Function: Metabolic and Endocrine - p. g360 35. Chapter 24: Lipodystrophy Syndromes - p. g376 36. Chapter 25: Lipoprotein Metabolism and the Treatment of Lipid Disorders - p. g395 37. Chapter 26: Metabolic Syndrome - p. g420 38. Chapter 27: Bariatric Procedures and Operations - p. g443 39. Part 4: Diabetes Mellitus - p. g467 40. Chapter 28: Development of the Endocrine Pancreas - p. g467 41. Chapter 29: Regulation of Islet Hormone Synthesis and Secretion - p. g482 42. Chapter 30: Mechanisms of Insulin Action - p. g495 43. Chapter 31: Classification and Diagnosis of Diabetes Mellitus - p. g516 44. Chapter 32: Autoimmune (Type 1) Diabetes Mellitus: Etiology, Pathogenesis, Prediction, and Prevention - p. g534 45. Chapter 33: Type 2 Diabetes Mellitus: Etiology, Pathogenesis, and Natural History - p. g551 46. Chapter 34: Diabetes Mellitus and Pregnancy - p. g551 47. Chapter 35: Hyperglycemia Secondary to Non-Traditional Diabetic Conditions - p. g605 48. Chapter 36: β Cell Glucose Toxicity and Oxidative Stress - p. g627 49. Chapter 37: Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State - p. g638 50. Chapter 38: Hypoglycemia and Hypoglycemic Syndromes - p. g650 51. Chapter 39: Treatment of Type 1 Diabetes Mellitus in Adults - p. g650 52. Chapter 40: Clinical Management of Type 2 Diabetes Mellitus - p. g686 53. Chapter 41: Pancreas and Islet Transplantation - p. g686 54. Chapter 42: Diabetes and Long-Term Complications - p. g724 55. Chapter 43: Diabetic Eye Disease - p. g738 56. Chapter 44: Diabetic Neuropathy - p. g752 57. Chapter 45: Diabetic Kidney Disease - p. g767 58. Chapter 46: Diabetic Foot and Vascular Complications - p. g785 59. Part 5: Parathyroid Gland, Calciotropic Hormones, and Bone Metabolism - p. g798 60. Chapter 47: Parathyroid Hormone and the Parathyroid Hormone Receptor Type 1 in the Regulation of Calcium and Phosphate Homeostasis and Bone Metabolism - p. g798 61. Chapter 48: Parathyroid Hormone-Related Protein - p. g816 62. Chapter 49: Calcitonin - p. g831 63. Chapter 50: Vitamin D: From Photosynthesis, Metabolism, and Action to Clinical Applications - p. g846 64. Chapter 51: Bone Development and Remodeling - p. g866 65. Chapter 52: Regulation of Calcium Homeostasis and Genetic Disorders That Affect Calcium Metabolism - p. g886 66. Chapter 53: Genetic Disorders of Phosphate Homeostasis - p. g905 67. Chapter 54: Primary Hyperparathyroidism - p. g919 68. Chapter 55: Malignancy-Associated Hypercalcemia - p. g939 69. Chapter 56: Surgical Management of Hyperparathyroidism - p. g951 70. Chapter 57: Pseudohypoparathyroidism, Albright’s Hereditary Osteodystrophy, and Progressive Osseous Heteroplasia: Disorders Caused byGNAS Mutations That Reduce Gsα Activity - p. g970 71. Chapter 58: Genetic Defects in Vitamin D Metabolism and Action - p. g986 72. Chapter 59: Hereditary Disorders of the Skeleton - p. g1004 73. Chapter 60: Osteoporosis - p. g1019 74. Chapter 61: CKD-MBD Syndrome: Chronic Kidney Disease Produced Disorders in Skeletal, Vascular, and Cardiac Tissues and Mineral Metabolism - p. g1037 75. Chapter 62: Disorders of Mineralization - p. g1037 76. Chapter 63: Paget Disease of Bone - p. g1063 77. Volume 2 - p. g1075 78. Part 6: Thyroid - p. g1075 79. Chapter 64: Anatomy and Development of the Thyroid - p. g1075 80. Chapter 65: Thyroid-Stimulating Hormone and TSH Receptor - p. g1075 81. Chapter 66: Thyroid Hormone Transporters and Metabolism - p. g1075 82. Chapter 67: Thyroid Hormone Action - p. g1125 83. Chapter 68: Thyroid Function Testing (Thyrotropin, Triiodothyronine, and Thyroxine) - p. g1139 84. Chapter 69: Thyroid Imaging - p. g1149 85. Chapter 70: Pathology of the Thyroid Gland - p. g1163 86. Chapter 71: Graves Disease - p. g1174 87. Chapter 72: Graves’ Orbitopathy - p. g1190 88. Chapter 73: Thyroiditis - p. g1211 89. Chapter 74: Hypothyroidism - p. g1231 90. Chapter 75: Thyroid and Pregnancy - p. g1248 91. Chapter 76: Iodine Nutrition and the Thyroid - p. g1263 92. Chapter 77: Euthyroid and Hyperthyroid Nodules and Goiter - p. g1274 93. Chapter 78: Differentiated Thyroid Cancer – Streamlining Diagnosis And Optimizing Management - p. g1294 94. Chapter 79: Medullary Thyroid Cancer - p. g1312 95. Chapter 80: Anaplastic (Undifferentiated) Thyroid Carcinoma - p. g1324 96. Chapter 81: Resistance to Thyroid Hormone and Genetic Defects of the Thyroid - p. g1335 97. Chapter 82: Surgical Management of Thyroid Disease - p. g1354 98. Chapter 83: Nonthyroidal Illness Syndrome - p. g1372 99. Chapter 84: Drugs and Thyroid - p. g1385 100. Part 7: Adrenal - p. g1404 101. Chapter 85: Adrenal Development and Homeostasis - p. g1404 102. Chapter 86: Genetic Disorders of the Adrenal Cortex - p. g1424 103. Chapter 87: Enzymes and Pathways of Human Steroidogenesis - p. g1443 104. Chapter 88: Mineralocorticoids: Physiology, Metabolism, Receptors, and Resistance - p. g1469 105. Chapter 89: Glucocorticoid Receptors: Mechanisms of Action in Health and Disease - p. g1481 106. Chapter 90: Adrenal Androgens, Adrenarche, and Adrenopause - p. g1493 107. Chapter 91: Adrenal Pathology - p. g1505 108. Chapter 92: Adrenal Gland Imaging - p. g1527 109. Chapter 93: Adrenal Insufficiency - p. g1548 110. Chapter 94: Defects of Adrenal Steroidogenesis - p. g1565 111. Chapter 95: Adrenal Genomics II: Familial and Sporadic Neoplasia - p. g1586 112. Chapter 96: Primary Aldosteronism - p. g1597 113. Chapter 97: Adrenocorticotropic Hormone–Independent Cushing Syndrome - p. g1610 114. Chapter 98: Adrenocortical Carcinoma - p. g1628 115. Chapter 99: Pheochromocytoma - p. g1639 116. Chapter 100: Adrenal Surgery - p. g1657 117. Part 8: Reproductive Endocrinology and Sexual Function - p. g1681 118. Chapter 101: Differences of Sex Development - p. g1681 119. Chapter 102: Endocrinology of Sexual Maturation and Puberty - p. g1712 120. Chapter 103: Endocrinology of Pubertal Disorders - p. g1728 121. Chapter 104: Transgender Healthcare - p. g1748 122. Part 9: Male Reproduction - p. g1756 123. Chapter 105: Gonadotropin Regulation and Androgen and Estrogen Physiology - p. g1756 124. Chapter 106: Hypogonadism: Pathogenesis, Diagnosis, and Treatment - p. g1777 125. Chapter 107: Testosterone Deficiency: Aging and Chronic Disease - p. g1801 126. Chapter 108: Gynecomastia - p. g1809 127. Chapter 109: Erectile Dysfunction - p. g1809 128. Chapter 110: Misuse and Abuse of Anabolic Hormones - p. g1842 129. Chapter 111: Regulation of Spermatogenesis - p. g1857 130. Chapter 112: Prevalence and Causes of Male Infertility - p. g1874 131. Chapter 113: Clinical Management of Male Infertility - p. g1888 132. Chapter 114: Male Contraception - p. g1903 133. Chapter 115: Testicular Dysgenesis Syndrome and Testicular Tumors - p. g1915 134. Chapter 116: Benign Prostatic Hyperplasia and Prostate Cancer - p. g1932 135. Part 10: Female Reproduction - p. g1946 136. Chapter 117: The Menstrual Cycle and Disorders of Ovulation - p. g1946 137. Chapter 118: Folliculogenesis, Ovulation, and Luteogenesis - p. g1968 138. Chapter 119: Ovarian Hormone Synthesis - p. g1984 139. Chapter 120: Estrogen and Progesterone Action - p. g2000 140. Chapter 121: Contraception - p. g2017 141. Chapter 122: Menopause and Perimenopause - p. g2027 142. Chapter 123: Female Infertility: Evaluation and Management - p. g2042 143. Chapter 124: Androgen Excess Disorders in Women - p. g2057 144. Chapter 125: Endometriosis - p. g2076 145. Chapter 126: Uterine Fibroids and Adenomyosis - p. g2089 146. Chapter 127: Hormonal Control of the Breast - p. g2101 147. Chapter 128: Sexual Dysfunction in the Female - p. g2120 148. Chapter 129: Hormonal Control of Human Pregnancy and Parturition - p. g2132 149. Chapter 130: Fetal and Neonatal Endocrinology - p. g2147 150. Chapter 131: Hormonal Changes and Pregnancy Testing - p. g2186 151. Part 11: Multisystem Endocrine Disorders - p. g2215 152. Chapter 132: Autoimmune Polyglandular Syndromes - p. g2215 153. Chapter 133: Multiple Endocrine Neoplasia Type 1 - p. g2234 154. Chapter 134: Multiple Endocrine Neoplasia Types 2 and 3, and Medullary Thyroid Carcinoma - p. g2253 155. Chapter 135: Neuroendocrine Tumor Syndromes - p. g2270 156. Chapter 136: Ectopic Hormone Syndromes - p. g2287 157. Chapter 137: Endocrine-Disrupting Chemicals and Human Health - p. g2300 158. Index - p. g2318
