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Microneedles in Drug Delivery and Therapeutics details the design, characterization and applications of this novel drug delivery system.Microneedles offer several advantages over traditional oral and parenteral approaches, due to their ability to be fabricated and altered in shape, size and material type, matched to specific treatment needs.This book covers the materials selection, design and fabrication approaches, and clinical translation of microneedles for a range of therapeutic applications, including: cancer therapy, gene and vaccine delivery, wound healing and more. Microneedles in Drug Delivery and Therapeutics is a forward-thinking resource for those working in the development of materials and devices for novel drug delivery.

  • Introduces the reader to skin anatomy and materials development in regard to microneedles as smart carriers for drug delivery, offering an interdisciplinary approach that will appeal to a wide audience
  • Covers a broad range of therapeutic applications, from ocular diseases and photodynamic therapy to sensing and cancer treatment
  • Provides an overview of the materials, design, fabrication, clinical translation, commercial aspects of microneedle development, and their applications in drug delivery

1. Chapter 1 Introduction of anatomy of the skin and microneedles as a smart carrier for drug delivery - p. 1 2. Chapter 2 Nanomedicine's delivery using microneedles - p. 33 3. Chapter 3 Types of microneedles for drug delivery - p. 65 4. Chapter 4 Stimuli-responsive microneedles for drug delivery - p. 89 5. Chapter 5 Silicon microneedles for drug delivery - p. 147 6. Chapter 6 Polymer-coated polymeric (PCP) microneedles for controlled regional drug delivery - p. 175 7. Chapter 7 Microneedles for local and transdermal drug delivery - p. 189 8. Chapter 8 Silicon microneedles for transdermal drug delivery - p. 209 9. Chapter 9 Microneedle for wound healing and dermal application - p. 235 10. Chapter 10 Microneedle for delivery of cosmeceuticals and enhancing skin appearance - p. 255 11. Chapter 11 Designing, characterization, and efficacy of microneedle patches in management and treatment of obesity - p. 285 12. Chapter 12 Microneedles for various ocular diseases - p. 303 13. Chapter 13 Microneedles deliver drugs to ophthalmic tissue - p. 327 14. Chapter 14 Potential of different types of microneedles in diagnosis and treatment of cancer - p. 343 15. Chapter 15 Microneedle-mediated photodynamic/immunotherapy - p. 379 16. Chapter 16 Microneedle-mediated gene delivery: A promising approach for diverse disease treatment - p. 407 17. Chapter 17 Microneedle-mediated vaccine delivery - p. 433 18. Chapter 18 Advancements and applications of 3D-printed microneedles for drug delivery - p. 449 19. Chapter 19 Microneedle-based electrochemical sensors for health monitoring - p. 481 20. Chapter 20 Future perspective, clinical translation, commercial challenges, and industrial success with microneedle-based products - p. 521 21. Index - p. 535

Descripcion
Descripción

Microneedles in Drug Delivery and Therapeutics details the design, characterization and applications of this novel drug delivery system.Microneedles offer several advantages over traditional oral and parenteral approaches, due to their ability to be fabricated and altered in shape, size and material type, matched to specific treatment needs.This book covers the materials selection, design and fabrication approaches, and clinical translation of microneedles for a range of therapeutic applications, including: cancer therapy, gene and vaccine delivery, wound healing and more. Microneedles in Drug Delivery and Therapeutics is a forward-thinking resource for those working in the development of materials and devices for novel drug delivery.

  • Introduces the reader to skin anatomy and materials development in regard to microneedles as smart carriers for drug delivery, offering an interdisciplinary approach that will appeal to a wide audience
  • Covers a broad range of therapeutic applications, from ocular diseases and photodynamic therapy to sensing and cancer treatment
  • Provides an overview of the materials, design, fabrication, clinical translation, commercial aspects of microneedle development, and their applications in drug delivery

1. Chapter 1 Introduction of anatomy of the skin and microneedles as a smart carrier for drug delivery - p. 1 2. Chapter 2 Nanomedicine's delivery using microneedles - p. 33 3. Chapter 3 Types of microneedles for drug delivery - p. 65 4. Chapter 4 Stimuli-responsive microneedles for drug delivery - p. 89 5. Chapter 5 Silicon microneedles for drug delivery - p. 147 6. Chapter 6 Polymer-coated polymeric (PCP) microneedles for controlled regional drug delivery - p. 175 7. Chapter 7 Microneedles for local and transdermal drug delivery - p. 189 8. Chapter 8 Silicon microneedles for transdermal drug delivery - p. 209 9. Chapter 9 Microneedle for wound healing and dermal application - p. 235 10. Chapter 10 Microneedle for delivery of cosmeceuticals and enhancing skin appearance - p. 255 11. Chapter 11 Designing, characterization, and efficacy of microneedle patches in management and treatment of obesity - p. 285 12. Chapter 12 Microneedles for various ocular diseases - p. 303 13. Chapter 13 Microneedles deliver drugs to ophthalmic tissue - p. 327 14. Chapter 14 Potential of different types of microneedles in diagnosis and treatment of cancer - p. 343 15. Chapter 15 Microneedle-mediated photodynamic/immunotherapy - p. 379 16. Chapter 16 Microneedle-mediated gene delivery: A promising approach for diverse disease treatment - p. 407 17. Chapter 17 Microneedle-mediated vaccine delivery - p. 433 18. Chapter 18 Advancements and applications of 3D-printed microneedles for drug delivery - p. 449 19. Chapter 19 Microneedle-based electrochemical sensors for health monitoring - p. 481 20. Chapter 20 Future perspective, clinical translation, commercial challenges, and industrial success with microneedle-based products - p. 521 21. Index - p. 535

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Ficha Técnica