Diabetes in Cardiovascular Disease is a current, expert resource focusing on the complex challenges of providing cardiovascular care to patients with diabetes. Designed as a companion to Braunwald’s Heart Disease, this interdisciplinary medical reference book bridges the gap between the cardiology and endocrinology communities of scientists and care providers, and highlights the emerging scientific and clinical topics that are relevant for cardiologists, diabetologists/endocrinologists, and the extended diabetes care team.
1. Cover image - p. cover 2. Title page - p. cover 3. Table of Contents - p. toc 4. Copyright - p. iv 5. Dedication - p. V 6. Contributors - p. V 7. Foreword - p. xi 8. Preface - p. xiii 9. Acknowledgments - p. xv 10. Updates to the Book - p. xv 11. Part I: Diabetes Mellitus - p. xv 12. 1. Definition and Epidemiology of Type 2 Diabetes Mellitus - p. xv 13. 2. Insulin Resistance: Pathophysiology, Molecular Mechanisms, Genetic Insights - p. 9 14. 3. Type 1 Diabetes: Pathophysiology, Molecular Mechanisms, Genetic Insights - p. 23 15. 4. The Metabolic Syndrome: Prevalence and Controversies in Clinical Context - p. 36 16. 5. Lifestyle Interventions for the Prevention of Type 2 Diabetes Mellitus - p. 43 17. 6. Pharmacologic and Surgical Interventions That Prevent or Worsen Type 2 Diabetes - p. 56 18. Part II: Diabetes and Atherosclerosis - p. 71 19. 7. Epidemiology of Coronary and Peripheral Atherosclerosis in Diabetes - p. 71 20. 8. Pathology of Diabetic Atherosclerosis: Composition, Characteristics, and Distribution - p. 86 21. 9. Vascular Biology of Atherosclerosis in Patients with Diabetes: Hyperglycemia, Insulin Resistance, and Hyperinsulinemia - p. 98 22. 10. Vascular Biology of Atherosclerosis in Patients with Diabetes: Dyslipidemia, Hypercoagulability, Endothelial Dysfunction, and Inflammation - p. 110 23. 11. Type 1 Diabetes and Associated Cardiovascular Risk and Disease - p. 126 24. Part III: Management of Coronary Heart Disease Risk and Disease in Patients with Diabetes - p. 137 25. 12. Effect of Lifestyle Interventions on Coronary Heart Disease Risk in Patients with Diabetes - p. 137 26. 13. Effect of Glucose Management on Coronary Heart Disease Risk in Patients with Diabetes - p. 154 27. 14. Effect of Blood Pressure Management on Coronary Heart Disease Risk in Patients with Type 2 Diabetes - p. 170 28. 15. Effect of Lipid Management on Coronary Heart Disease Risk in Patients with Diabetes - p. 180 29. 16. Effect of Antiplatelet Therapy on Coronary Heart Disease Risk in Patients with Diabetes Mellitus - p. 202 30. 17. Role of Percutaneous Coronary Intervention in Patients with Diabetes - p. 216 31. 18. Role of Coronary Artery Bypass Surgery in Diabetes and Perioperative Glucose Management - p. 227 32. Part IV: Epidemiology and Management of Acute Coronary Syndromes in Patients with Diabetes - p. 238 33. 19. Epidemiology of Acute Coronary Syndromes in Patients with Diabetes - p. 238 34. 20. Hyperglycemia and Acute Coronary Syndromes: Association with Outcomes and Management - p. 250 35. 21. Antiplatelet and Antithrombotic Therapy in Diabetic Patients with Acute Coronary Syndrome - p. 261 36. 22. Role of Primary Invasive Strategy and Revascularization in Diabetic Patients with Acute Coronary Syndromes - p. 270 37. Part V: Heart Failure in Diabetes - p. 280 38. 23. Epidemiology of Heart Failure in Diabetes - p. 280 39. 24. Diabetic Cardiomyopathy: Mediators and Mechanisms - p. 289 40. 25. Prevention of Heart Failure in Patients with Diabetes - p. 301 41. 26. Treatment of Heart Failure in Diabetes: Systolic Dysfunction, Diastolic Dysfunction, and Post-Acute Coronary Syndrome - p. 312 42. Part VI: Other Diabetes-Related Cardiovascular Considerations - p. 327 43. 27. Peripheral Artery Disease in Diabetes - p. 327 44. 28. Cerebrovascular Disease in Patients with Diabetes - p. 340 45. 29. Cardiovascular Autonomic Neuropathy - p. 360 46. 30. Disparities in Diabetes Risk, Cardiovascular Consequences, and Care: Women, Ethnic Minorities, and the Elderly - p. 368 47. 31. The Quality Chasm: Diabetes Mellitus - p. 378 48. Index - p. 385
Diabetes in Cardiovascular Disease is a current, expert resource focusing on the complex challenges of providing cardiovascular care to patients with diabetes. Designed as a companion to Braunwald’s Heart Disease, this interdisciplinary medical reference book bridges the gap between the cardiology and endocrinology communities of scientists and care providers, and highlights the emerging scientific and clinical topics that are relevant for cardiologists, diabetologists/endocrinologists, and the extended diabetes care team.
1. Cover image - p. cover 2. Title page - p. cover 3. Table of Contents - p. toc 4. Copyright - p. iv 5. Dedication - p. V 6. Contributors - p. V 7. Foreword - p. xi 8. Preface - p. xiii 9. Acknowledgments - p. xv 10. Updates to the Book - p. xv 11. Part I: Diabetes Mellitus - p. xv 12. 1. Definition and Epidemiology of Type 2 Diabetes Mellitus - p. xv 13. 2. Insulin Resistance: Pathophysiology, Molecular Mechanisms, Genetic Insights - p. 9 14. 3. Type 1 Diabetes: Pathophysiology, Molecular Mechanisms, Genetic Insights - p. 23 15. 4. The Metabolic Syndrome: Prevalence and Controversies in Clinical Context - p. 36 16. 5. Lifestyle Interventions for the Prevention of Type 2 Diabetes Mellitus - p. 43 17. 6. Pharmacologic and Surgical Interventions That Prevent or Worsen Type 2 Diabetes - p. 56 18. Part II: Diabetes and Atherosclerosis - p. 71 19. 7. Epidemiology of Coronary and Peripheral Atherosclerosis in Diabetes - p. 71 20. 8. Pathology of Diabetic Atherosclerosis: Composition, Characteristics, and Distribution - p. 86 21. 9. Vascular Biology of Atherosclerosis in Patients with Diabetes: Hyperglycemia, Insulin Resistance, and Hyperinsulinemia - p. 98 22. 10. Vascular Biology of Atherosclerosis in Patients with Diabetes: Dyslipidemia, Hypercoagulability, Endothelial Dysfunction, and Inflammation - p. 110 23. 11. Type 1 Diabetes and Associated Cardiovascular Risk and Disease - p. 126 24. Part III: Management of Coronary Heart Disease Risk and Disease in Patients with Diabetes - p. 137 25. 12. Effect of Lifestyle Interventions on Coronary Heart Disease Risk in Patients with Diabetes - p. 137 26. 13. Effect of Glucose Management on Coronary Heart Disease Risk in Patients with Diabetes - p. 154 27. 14. Effect of Blood Pressure Management on Coronary Heart Disease Risk in Patients with Type 2 Diabetes - p. 170 28. 15. Effect of Lipid Management on Coronary Heart Disease Risk in Patients with Diabetes - p. 180 29. 16. Effect of Antiplatelet Therapy on Coronary Heart Disease Risk in Patients with Diabetes Mellitus - p. 202 30. 17. Role of Percutaneous Coronary Intervention in Patients with Diabetes - p. 216 31. 18. Role of Coronary Artery Bypass Surgery in Diabetes and Perioperative Glucose Management - p. 227 32. Part IV: Epidemiology and Management of Acute Coronary Syndromes in Patients with Diabetes - p. 238 33. 19. Epidemiology of Acute Coronary Syndromes in Patients with Diabetes - p. 238 34. 20. Hyperglycemia and Acute Coronary Syndromes: Association with Outcomes and Management - p. 250 35. 21. Antiplatelet and Antithrombotic Therapy in Diabetic Patients with Acute Coronary Syndrome - p. 261 36. 22. Role of Primary Invasive Strategy and Revascularization in Diabetic Patients with Acute Coronary Syndromes - p. 270 37. Part V: Heart Failure in Diabetes - p. 280 38. 23. Epidemiology of Heart Failure in Diabetes - p. 280 39. 24. Diabetic Cardiomyopathy: Mediators and Mechanisms - p. 289 40. 25. Prevention of Heart Failure in Patients with Diabetes - p. 301 41. 26. Treatment of Heart Failure in Diabetes: Systolic Dysfunction, Diastolic Dysfunction, and Post-Acute Coronary Syndrome - p. 312 42. Part VI: Other Diabetes-Related Cardiovascular Considerations - p. 327 43. 27. Peripheral Artery Disease in Diabetes - p. 327 44. 28. Cerebrovascular Disease in Patients with Diabetes - p. 340 45. 29. Cardiovascular Autonomic Neuropathy - p. 360 46. 30. Disparities in Diabetes Risk, Cardiovascular Consequences, and Care: Women, Ethnic Minorities, and the Elderly - p. 368 47. 31. The Quality Chasm: Diabetes Mellitus - p. 378 48. Index - p. 385