Diabetic Neuropathy identifies the most accurate early biomarkers of nerve damage to better understand pathophysiology and diagnose diabetic neuropathy in the clinical care of patients, and in particular, permit an accurate evaluation of future therapies in clinical trials. This succinct reference focuses on the current data and research on diabetic neuropathy and is essential reading for researchers in endocrinology, neurology and pharmacology, along with clinicians that need to better understand the novel pathogenetic pathways leading to diabetic neuropathy and the treatments.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. List of contributors - p. xiii 8. About the editor - p. xvii 9. Foreword - p. xix 10. Preface - p. xxi 11. Acknowledgments - p. xxiii 12. Chapter 1. Classification, risk factors, and clinical presentation diabetic neuropathy - p. 1 13. Chapter 2. Pathologic basis for diabetic neuropathy in humans - p. 11 14. Chapter 3. Electrodiagnostic evaluation in diabetic neuropathy - p. 35 15. Chapter 4. Advances in screening, early diagnosis, and accurate staging of diabetic neuropathy - p. 47 16. Chapter 5. Skin biopsy analysis in diabetic neuropathy - p. 79 17. Chapter 6. Central nervous system involvement in diabetic peripheral neuropathy - p. 91 18. Chapter 7. Spinal cord involvement in diabetic neuropathy and neuropathic pain - p. 103 19. Chapter 8. The conundrum and enigma of painful and painless neuropathy - p. 123 20. Chapter 9. Motor dysfunction in diabetes - p. 135 21. Chapter 10. Diabetic autonomic neuropathy, measurement and management; part 1: measurement - p. 163 22. Chapter 11. Diabetic neuropathy in children and youth - p. 185 23. Chapter 12. Treatment-induced painful diabetic neuropathy - p. 201 24. Chapter 13. Health economics of diabetic foot disease: costs of diabetic neuropathy and diabetic foot - p. 211 25. Chapter 14. Diabetic foot - p. 223 26. Chapter 15. Management of diabetic foot disease - p. 235 27. Chapter 16. Strategies for the prevention or reversal of neuropathy - p. 259 28. Chapter 17. Treatment of diabetic peripheral neuropathy: technologies, exercise, and alternative treatments - p. 283 29. Chapter 18. Treatment of diabetic polyneuropathy - p. 299 30. Chapter 19. Diabetic autonomic neuropathy, measurement and management; part II: management - p. 313 31. Chapter 20. Translating a treatment for diabetic peripheral neuropathy from rodents to humans: can a case be made for fish oil and salsalate? - p. 337 32. Chapter 21. Bedside clinical features and translational snapshots of diabetic polyneuropathy - p. 349 33. Index - p. 367
Diabetic Neuropathy identifies the most accurate early biomarkers of nerve damage to better understand pathophysiology and diagnose diabetic neuropathy in the clinical care of patients, and in particular, permit an accurate evaluation of future therapies in clinical trials. This succinct reference focuses on the current data and research on diabetic neuropathy and is essential reading for researchers in endocrinology, neurology and pharmacology, along with clinicians that need to better understand the novel pathogenetic pathways leading to diabetic neuropathy and the treatments.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. List of contributors - p. xiii 8. About the editor - p. xvii 9. Foreword - p. xix 10. Preface - p. xxi 11. Acknowledgments - p. xxiii 12. Chapter 1. Classification, risk factors, and clinical presentation diabetic neuropathy - p. 1 13. Chapter 2. Pathologic basis for diabetic neuropathy in humans - p. 11 14. Chapter 3. Electrodiagnostic evaluation in diabetic neuropathy - p. 35 15. Chapter 4. Advances in screening, early diagnosis, and accurate staging of diabetic neuropathy - p. 47 16. Chapter 5. Skin biopsy analysis in diabetic neuropathy - p. 79 17. Chapter 6. Central nervous system involvement in diabetic peripheral neuropathy - p. 91 18. Chapter 7. Spinal cord involvement in diabetic neuropathy and neuropathic pain - p. 103 19. Chapter 8. The conundrum and enigma of painful and painless neuropathy - p. 123 20. Chapter 9. Motor dysfunction in diabetes - p. 135 21. Chapter 10. Diabetic autonomic neuropathy, measurement and management; part 1: measurement - p. 163 22. Chapter 11. Diabetic neuropathy in children and youth - p. 185 23. Chapter 12. Treatment-induced painful diabetic neuropathy - p. 201 24. Chapter 13. Health economics of diabetic foot disease: costs of diabetic neuropathy and diabetic foot - p. 211 25. Chapter 14. Diabetic foot - p. 223 26. Chapter 15. Management of diabetic foot disease - p. 235 27. Chapter 16. Strategies for the prevention or reversal of neuropathy - p. 259 28. Chapter 17. Treatment of diabetic peripheral neuropathy: technologies, exercise, and alternative treatments - p. 283 29. Chapter 18. Treatment of diabetic polyneuropathy - p. 299 30. Chapter 19. Diabetic autonomic neuropathy, measurement and management; part II: management - p. 313 31. Chapter 20. Translating a treatment for diabetic peripheral neuropathy from rodents to humans: can a case be made for fish oil and salsalate? - p. 337 32. Chapter 21. Bedside clinical features and translational snapshots of diabetic polyneuropathy - p. 349 33. Index - p. 367