Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituitary-adrenal (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.
1. Chapter One: Introduction to neurobiology and pharmacology of stress - p. 1 2. Chapter Two: Mechanisms underlying stress effects on the brain: Basic concepts and clinical implications - p. 21 3. Chapter Three: Early life stress and brain development: Neurobiological and behavioral effects of chronic stress - p. 49 4. Chapter Four: Molecular mechanism underlying stress response and adaptation - p. 81 5. Chapter Five: Effects of stress on cognitive performance - p. 109 6. Chapter Six: Understanding the connection between stress and sleep: From underlying mechanisms to therapeutic solutions - p. 137 7. Chapter Seven: Stress-related psychiatric disorders - p. 161 8. Chapter Eight: Stress and the gut microbiota-brain axis - p. 175 9. Chapter Nine: Epigenetic regulation of stress - p. 205 10. Chapter Ten: Mapping brain neural networks in stress brain connectivity - p. 239 11. Chapter Eleven: Stress-related neurodegenerative diseases: Molecular mechanisms implicated in neurodegeneration and therapeutic strategies - p. 253 12. Chapter Twelve: The stress-immune system axis: Exploring the interplay between stress and immunity - p. 289 13. Chapter Thirteen: Stress and gender differences in brain development - p. 319 14. Chapter Fourteen: Models developed to explain the effects of stress on brain and behavior - p. 339 15. Chapter Fifteen: Stress in specific population: Cognitive decline in aging, occupational challenges, strategies for medical professionals - p. 363 16. Chapter Sixteen: Addiction and stress: Exploring the reward pathways in brain affected by different drugs - p. 381 17. Chapter Seventeen: Stress-induced neurodegeneration and behavioral alterations in Caenorhabditis elegans: Insights into the evolutionary conservation of stress-related pathways and implications for human health - p. 405 18. Chapter Eighteen: The neuroscientific basis of post-traumatic stress disorder (PTSD): From brain to treatment - p. 427 19. Chapter Nineteen: Effect of stress on neuronal cell: Morphological to molecular approach - p. 469
Stress and The Brain: Evidence from Molecular Mechanisms to Interventions and Therapies is a comprehensive exploration of how stress affects the brain at a molecular level and its broader implications for mental and neurological health. The book delves into the mechanisms by which stress triggers changes in brain function, including the activation of the hypothalamic-pituitary-adrenal (HPA) axis, synaptic plasticity alterations, oxidative stress, neuroinflammation, and mitochondrial dysfunction. It examines how these molecular processes contribute to conditions such as neurodegeneration, anxiety, depression, and other stress-related disorders. Furthermore, the book provides an in-depth analysis of current therapeutic interventions, both pharmacological and behavioral, as well as natural antidotes that aim to mitigate the adverse effects of stress on the brain. By synthesizing evidence from cutting-edge research, this book offers valuable insights for scientists, clinicians, and mental health professionals seeking to understand and address the complex interplay between stress and brain health.
1. Chapter One: Introduction to neurobiology and pharmacology of stress - p. 1 2. Chapter Two: Mechanisms underlying stress effects on the brain: Basic concepts and clinical implications - p. 21 3. Chapter Three: Early life stress and brain development: Neurobiological and behavioral effects of chronic stress - p. 49 4. Chapter Four: Molecular mechanism underlying stress response and adaptation - p. 81 5. Chapter Five: Effects of stress on cognitive performance - p. 109 6. Chapter Six: Understanding the connection between stress and sleep: From underlying mechanisms to therapeutic solutions - p. 137 7. Chapter Seven: Stress-related psychiatric disorders - p. 161 8. Chapter Eight: Stress and the gut microbiota-brain axis - p. 175 9. Chapter Nine: Epigenetic regulation of stress - p. 205 10. Chapter Ten: Mapping brain neural networks in stress brain connectivity - p. 239 11. Chapter Eleven: Stress-related neurodegenerative diseases: Molecular mechanisms implicated in neurodegeneration and therapeutic strategies - p. 253 12. Chapter Twelve: The stress-immune system axis: Exploring the interplay between stress and immunity - p. 289 13. Chapter Thirteen: Stress and gender differences in brain development - p. 319 14. Chapter Fourteen: Models developed to explain the effects of stress on brain and behavior - p. 339 15. Chapter Fifteen: Stress in specific population: Cognitive decline in aging, occupational challenges, strategies for medical professionals - p. 363 16. Chapter Sixteen: Addiction and stress: Exploring the reward pathways in brain affected by different drugs - p. 381 17. Chapter Seventeen: Stress-induced neurodegeneration and behavioral alterations in Caenorhabditis elegans: Insights into the evolutionary conservation of stress-related pathways and implications for human health - p. 405 18. Chapter Eighteen: The neuroscientific basis of post-traumatic stress disorder (PTSD): From brain to treatment - p. 427 19. Chapter Nineteen: Effect of stress on neuronal cell: Morphological to molecular approach - p. 469
