This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of head and neck pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Head and Neck is a one-stop reference for accurate, complete pathology reports—ideal as a day-to-day reference or as a reliable teaching resource.
Provides a clear framework for a better understanding of the clinical and histopathologic appearances of more than 325 new or evolving entities of the head and neck and endocrine organs
Features updates on recent changes in the field and current information from the AJCC Cancer Staging Manual, 8th Edition, and the World Health Organization Classification of Head and Neck Tumours, 5th Edition
Covers numerous new diagnostic entities, including intraductal carcinoma, sclerosing polycystic adenoma, microsecretory adenocarcinoma, adamantinoma-like Ewing sarcoma, SMARCB1- and SMARCA4-deficient carcinomas, and HPV-related multiphenotypic sinonasal carcinoma
Contains major updates on sinonasal tract, salivary gland, and odontogenic tumors; oropharyngeal squamous cell carcinoma and its correct classification and staging; the recent significant reclassification of neuroendocrine tumors; and changes in terminology and identification for head and neck soft tissue tumors
Suggests supporting studies in a realistic clinical context, with tables and immunohistochemical charts that assist with management decisions and prognostic outcome predictions
Features more than 3,200 images, including full-color drawings of head and neck anatomy, development pathway drawings, staging protocol illustrations, and genetic pathway graphics; radiologic images, clinical photographs, and gross images; and histology, histochemistry, immunohistochemistry, in situ hybridization, and molecular images; as well as more than 2,600 additional online-only images
Employs consistently templated chapters, bulleted content, key facts, and annotated images for quick, expert reference at the point of care
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedications - p. iii 6. Contributing Author - p. v 7. Preface - p. v 8. Acknowledgments - p. ix 9. Sections - p. xi 10. SECTION 1: NASAL CAVITY AND PARANASAL SINUSES - p. xiii 11. List of Tables - p. xiii 12. Chapter 1: Nose and Paranasal Sinuses - p. xiii 13. CONGENITAL/GENETIC/HEREDITARY - p. 5 14. Chapter 2: Nasal Neuroglial Heterotopia - p. 5 15. Chapter 3: Nasal Dermoid Cyst and Sinus - p. 7 16. INFECTIOUS - p. 9 17. Chapter 4: Allergic Fungal Sinusitis - p. 9 18. Chapter 5: Invasive Fungal Rhinosinusitis - p. 13 19. Chapter 6: Mycetoma - p. 15 20. Chapter 7: Rhinoscleroma - p. 16 21. Chapter 8: Rhinosporidiosis - p. 17 22. Chapter 9: Mycobacterium leprae Infection - p. 19 23. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 21 24. Chapter 10: Chronic Rhinosinusitis - p. 21 25. Chapter 11: Granulomatosis With Polyangiitis - p. 25 26. Chapter 12: Eosinophilic Angiocentric Fibrosis - p. 31 27. REACTIVE AND HAMARTOMAS - p. 35 28. Chapter 13: Sinonasal Inflammatory Polyp - p. 35 29. Chapter 14: Antrochoanal Polyp - p. 39 30. Chapter 15: Mucocele of Paranasal Sinus - p. 41 31. Chapter 16: Sinonasal Hamartoma - p. 43 32. Chapter 17: Nasal Chondromesenchymal Hamartoma - p. 49 33. Chapter 18: Extranodal Sinus Histiocytosis With Massive Lymphadenopathy - p. 51 34. Chapter 19: Myospherulosis - p. 55 35. BENIGN NEOPLASM - p. 57 36. Chapter 20: Sinonasal Papilloma - p. 57 37. Chapter 21: Pleomorphic Adenoma, Sinonasal Tract - p. 65 38. Chapter 22: Meningioma, Sinonasal Tract - p. 67 39. Chapter 23: Ameloblastoma, Sinonasal Tract - p. 71 40. Chapter 24: Ectopic Pituitary Neuroendocrine Tumor - p. 73 41. Chapter 25: Lobular Capillary Hemangioma (Pyogenic Granuloma) - p. 79 42. Chapter 26: Sinonasal Tract Angiofibroma - p. 83 43. Chapter 27: Schwannoma/Neurofibroma, Sinonasal Tract - p. 87 44. Chapter 28: Leiomyoma and Smooth Muscle Tumors of Uncertain Malignant Potential - p. 91 45. Chapter 29: Fibromatosis/Desmoid-Type Fibromatosis - p. 95 46. Chapter 30: Solitary Fibrous Tumor, Sinonasal Tract - p. 97 47. BORDERLINE NEOPLASM - p. 101 48. Chapter 31: Glomangiopericytoma - p. 101 49. MALIGNANT NEOPLASM - p. 105 50. Chapter 32: Squamous Cell Carcinoma, Sinonasal Tract - p. 105 51. Chapter 33: NUT Carcinoma - p. 113 52. Chapter 34: SWI/SNF Complex-Deficient Sinonasal Carcinomas - p. 115 53. Chapter 35: Lymphoepithelial Carcinoma, Sinonasal Tract - p. 119 54. Chapter 36: Sinonasal Undifferentiated Carcinoma - p. 121 55. Chapter 37: Teratocarcinosarcoma - p. 127 56. Chapter 38: HPV-Related Multiphenotypic Sinonasal Carcinoma - p. 132 57. Chapter 39: Sinonasal Adenocarcinoma, Intestinal Type - p. 137 58. Chapter 40: Sinonasal Nonintestinal-Nonsalivary Adenocarcinoma - p. 143 59. Chapter 41: Sinonasal Renal Cell-Like Adenocarcinoma - p. 151 60. Chapter 42: Olfactory Neuroblastoma - p. 153 61. Chapter 43: Sinonasal Neuroendocrine Carcinoma - p. 163 62. Chapter 44: Mucosal Melanoma, Sinonasal Tract - p. 169 63. Chapter 45: Alveolar Rhabdomyosarcoma, Sinonasal Tract - p. 175 64. Chapter 46: Ewing Sarcoma, Including Sinonasal Adamantinoma-Like - p. 181 65. Chapter 47: Biphenotypic Sinonasal Sarcoma - p. 187 66. Chapter 48: Leiomyosarcoma, Sinonasal Tract - p. 191 67. Chapter 49: Malignant Peripheral Nerve Sheath Tumor, Sinonasal Tract - p. 197 68. Chapter 50: Fibrosarcoma, Sinonasal Tract - p. 201 69. Chapter 51: Angiosarcoma, Sinonasal Tract - p. 205 70. Chapter 52: Mesenchymal Chondrosarcoma, Sinonasal Tract - p. 209 71. Chapter 53: Undifferentiated Pleomorphic Sarcoma, Sinonasal Tract - p. 211 72. Chapter 54: Extranodal NK-/T-Cell Lymphoma, Nasal Type - p. 215 73. Chapter 55: Metastatic/Secondary Tumors, Sinonasal Tract - p. 221 74. SPECIMEN EXAMINATION, NASAL CAVITY & PARANASAL SINUSES - p. 223 75. Chapter 56: Specimen Examination and Staging Tools, Oropharynx - p. 223 76. Chapter 57: Specimen Examination and Staging Tools, Nasopharynx - p. 227 77. SECTION 2: PHARYNX (NASAL, HYPO-) - p. 231 78. Chapter 58: Pharynx - p. 231 79. CONGENITAL/GENETIC/HEREDITARY - p. 235 80. Chapter 59: Tornwaldt Cyst - p. 235 81. Chapter 60: Rathke Cleft Cyst - p. 236 82. BENIGN NEOPLASM - p. 237 83. Chapter 61: Dermoid - p. 237 84. MALIGNANT NEOPLASM - p. 239 85. Chapter 62: Low-Grade Nasopharyngeal Papillary Adenocarcinoma - p. 239 86. Chapter 63: Nasopharyngeal Carcinoma, Nonkeratinizing Types - p. 243 87. Chapter 64: Nasopharyngeal Carcinoma, Keratinizing Type - p. 253 88. Chapter 65: Nasopharyngeal Carcinoma, Basaloid Squamous Cell Carcinoma - p. 255 89. Chapter 66: Diffuse Large B-Cell Lymphoma NOS - p. 259 90. SECTION 3: LARYNX AND TRACHEA - p. 263 91. Chapter 67: Larynx - p. 263 92. CONGENITAL/GENETIC/HEREDITARY - p. 267 93. Chapter 68: Laryngocele and Laryngeal Cysts - p. 267 94. Chapter 69: Tracheopathia Osteoplastica - p. 269 95. INFECTIOUS - p. 271 96. Chapter 70: Laryngitis: Viral, Bacterial, Fungal - p. 271 97. REACTIVE - p. 275 98. Chapter 71: Vocal Cord Nodules and Polyps - p. 275 99. Chapter 72: Reactive Epithelial Changes - p. 279 100. Chapter 73: Contact Ulcer - p. 283 101. Chapter 74: Amyloid (Amyloidoma) - p. 285 102. BENIGN NEOPLASM - p. 287 103. Chapter 75: Squamous Papilloma - p. 287 104. Chapter 76: Granular Cell Tumor, Larynx - p. 291 105. Chapter 77: Adult Rhabdomyoma - p. 293 106. Chapter 78: Inflammatory Myofibroblastic Tumor - p. 295 107. Chapter 79: Paraganglioma, Larynx - p. 299 108. Chapter 80: Chondroma - p. 301 109. BORDERLINE NEOPLASM - p. 303 110. Chapter 81: EBV-Associated Smooth Muscle Tumor - p. 303 111. MALIGNANT NEOPLASM - p. 305 112. Chapter 82: Keratinizing Dysplasia and Carcinoma In Situ - p. 305 113. Chapter 83: Conventional Squamous Cell Carcinoma - p. 313 114. Chapter 84: Verrucous Carcinoma - p. 321 115. Chapter 85: Spindle Cell Squamous Cell Carcinoma - p. 325 116. Chapter 86: Papillary Squamous Cell Carcinoma - p. 331 117. Chapter 87: Basaloid Squamous Cell Carcinoma - p. 335 118. Chapter 88: Adenosquamous Carcinoma - p. 339 119. Chapter 89: Neuroendocrine Neoplasms, Larynx - p. 343 120. Chapter 90: Chondrosarcoma - p. 353 121. Chapter 91: Metastatic/Secondary Tumors, Larynx and Trachea - p. 357 122. SPECIMEN EXAMINATION, LARYNX - p. 359 123. Chapter 92: Specimen Examination and Staging Tools, Larynx and Trachea - p. 359 124. SECTION 4: ORAL CAVITY - p. 361 125. Chapter 93: Tongue - p. 361 126. Chapter 94: Oral Mucosae - p. 365 127. CONGENITAL/GENETIC/HEREDITARY - p. 367 128. Chapter 95: Ectopic (Lingual) Thyroid - p. 367 129. Chapter 96: White Sponge Nevus - p. 369 130. INFECTIOUS - p. 371 131. Chapter 97: Multifocal Epithelial Hyperplasia (Heck Disease) - p. 371 132. Chapter 98: Oral Hairy Leukoplakia - p. 373 133. Chapter 99: Oral Infections - p. 375 134. Chapter 100: Oral Syphilis - p. 379 135. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 383 136. Chapter 101: Aphthous Stomatitis - p. 383 137. Chapter 102: Pemphigus Vulgaris - p. 389 138. Chapter 103: Mucous Membrane Pemphigoid - p. 391 139. Chapter 104: Oral Lichen Planus - p. 393 140. Chapter 105: Erythema Multiforme - p. 397 141. Chapter 106: Lupus Erythematosus - p. 399 142. REACTIVE - p. 403 143. Chapter 107: Frictional Hyperkeratosis - p. 403 144. Chapter 108: Pseudoepitheliomatous Hyperplasia - p. 404 145. Chapter 109: Necrotizing Sialometaplasia - p. 405 146. Chapter 110: Traumatic Ulcerative Granuloma With Stromal Eosinophilia - p. 407 147. Chapter 111: Giant Cell Fibroma - p. 409 148. Chapter 112: Amalgam Tattoo - p. 410 149. Chapter 113: Tobacco Changes - p. 411 150. Chapter 114: Parulis - p. 413 151. NONNEOPLASTIC LESIONS - p. 414 152. Chapter 115: Fordyce Granules - p. 414 153. Chapter 116: Mucocele and Ranula - p. 415 154. Chapter 117: Verruciform Xanthoma - p. 417 155. Chapter 118: Hairy Tongue - p. 418 156. Chapter 119: Geographic Tongue - p. 419 157. Chapter 120: Juxtaoral Organ of Chievitz - p. 421 158. Chapter 121: Heterotopic Salivary Glands - p. 422 159. BENIGN NEOPLASM - p. 423 160. Chapter 122: Squamous Papilloma (Including Verruca and Condyloma) - p. 423 161. Chapter 123: Fibroma, Oral Cavity - p. 427 162. Chapter 124: Pyogenic Granuloma - p. 429 163. Chapter 125: Peripheral Giant Cell Granuloma - p. 431 164. Chapter 126: Peripheral Ossifying Fibroma - p. 433 165. Chapter 127: Mucosal Neuroma - p. 435 166. Chapter 128: Solitary Circumscribed Neuroma - p. 437 167. Chapter 129: Acquired Melanocytic Nevus - p. 439 168. Chapter 130: Melanoacanthoma - p. 443 169. Chapter 131: Oral Lymphangioma - p. 444 170. Chapter 132: Teratoma, Oral Cavity - p. 445 171. BORDERLINE NEOPLASM - p. 447 172. Chapter 133: Congenital Granular Cell Epulis - p. 447 173. Chapter 134: Granular Cell Tumor, Oral Cavity - p. 449 174. Chapter 135: Melanotic Neuroectodermal Tumor of Infancy - p. 453 175. Chapter 136: Ectomesenchymal Chondromyxoid Tumor - p. 455 176. Chapter 137: GLI1-Altered Soft Tissue Tumor - p. 459 177. MALIGNANT NEOPLASM - p. 461 178. Chapter 138: Dysplasia and Carcinoma In Situ - p. 461 179. Chapter 139: Proliferative Verrucous Leukoplakia - p. 467 180. Chapter 140: Squamous Cell Carcinoma, Oral Cavity - p. 469 181. Chapter 141: Mucosal Melanoma, Oral Cavity - p. 475 182. Chapter 142: Extraskeletal Myxoid Chondrosarcoma - p. 479 183. Chapter 143: Angiosarcoma, Oral Cavity - p. 481 184. Chapter 144: Kaposi Sarcoma, Oral Cavity - p. 483 185. Chapter 145: Metastatic/Secondary Tumors: Oral Cavity; Jaw - p. 485 186. SPECIMEN EXAMINATION, LIP AND ORAL CAVITY - p. 487 187. Chapter 146: Specimen Examination and Staging Tools, Lip and Oral Cavity - p. 487 188. SECTION 5: OROPHARYNX - p. 489 189. INFECTIOUS - p. 489 190. Chapter 147: Infectious Mononucleosis - p. 489 191. Chapter 148: HIV Infection of Tonsils and Adenoids - p. 495 192. REACTIVE - p. 499 193. Chapter 149: Lymphangiomatous Polyp - p. 499 194. MALIGNANT NEOPLASM - p. 501 195. Chapter 150: Oropharyngeal Carcinoma - p. 501 196. SECTION 6: SALIVARY GLANDS - p. 505 197. Chapter 151: Major Salivary Glands - p. 505 198. INFECTIOUS - p. 509 199. Chapter 152: HIV Salivary Gland Disease - p. 509 200. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 511 201. Chapter 153: Benign Lymphoepithelial Cyst - p. 511 202. Chapter 154: Benign Lymphoepithelial Lesion - p. 513 203. Chapter 155: Sjögren Syndrome - p. 515 204. Chapter 156: IgG4-Related Salivary Gland Disease - p. 519 205. REACTIVE - p. 523 206. Chapter 157: Oncocytosis (Oncocytic Hyperplasia) - p. 523 207. Chapter 158: Sialolithiasis - p. 524 208. BENIGN NEOPLASM - p. 525 209. Chapter 159: Pleomorphic Adenoma - p. 525 210. Chapter 160: Basal Cell Adenoma - p. 535 211. Chapter 161: Myoepithelioma - p. 539 212. Chapter 162: Warthin Tumor (Papillary Cystadenoma Lymphomatosum) - p. 543 213. Chapter 163: Oncocytoma - p. 547 214. Chapter 164: Canalicular Adenoma - p. 553 215. Chapter 165: Cystadenoma - p. 555 216. Chapter 166: Ductal Papillomas - p. 557 217. Chapter 167: Salivary Gland Adenoma: Lymphadenoma, Sebaceous Lymphadenoma, and Sebaceous Adenoma - p. 561 218. Chapter 168: Sclerosing Polycystic Adenoma - p. 563 219. Chapter 169: Keratocystoma - p. 565 220. Chapter 170: Sialolipoma - p. 566 221. Chapter 171: Hemangioma, Parotid Gland - p. 567 222. BORDERLINE NEOPLASM - p. 569 223. Chapter 172: Sialoblastoma - p. 569 224. MALIGNANT NEOPLASM - p. 573 225. Chapter 173: Mucoepidermoid Carcinoma, Salivary - p. 573 226. Chapter 174: Adenoid Cystic Carcinoma - p. 583 227. Chapter 175: Acinic Cell Carcinoma - p. 591 228. Chapter 176: Secretory Carcinoma, Salivary Gland - p. 599 229. Chapter 177: Microsecretory Adenocarcinoma - p. 603 230. Chapter 178: Polymorphous Adenocarcinoma, Low-Grade Subtype - p. 605 231. Chapter 179: Polymorphous Adenocarcinoma, Cribriform Subtype - p. 611 232. Chapter 180: Hyalinizing Clear Cell Carcinoma - p. 613 233. Chapter 181: Basal Cell Adenocarcinoma - p. 619 234. Chapter 182: Intraductal Carcinoma - p. 623 235. Chapter 183: Salivary Duct Carcinoma - p. 625 236. Chapter 184: Myoepithelial Carcinoma - p. 635 237. Chapter 185: Epithelial-Myoepithelial Carcinoma - p. 639 238. Chapter 186: Carcinoma Ex-Pleomorphic Adenoma - p. 645 239. Chapter 187: Mucinous Adenocarcinoma - p. 655 240. Chapter 188: Sclerosing Microcystic Adenocarcinoma - p. 659 241. Chapter 189: Lymphoepithelial Carcinoma, Salivary Gland - p. 661 242. Chapter 190: Sebaceous Carcinoma and Sebaceous Lymphadenocarcinoma - p. 667 243. Chapter 191: Adenocarcinoma, Not Otherwise Specified - p. 669 244. Chapter 192: Small Cell Neuroendocrine Carcinoma, Salivary Gland - p. 671 245. Chapter 193: Lymphoma, Salivary Gland - p. 675 246. Chapter 194: Metastatic/Secondary Tumors, Salivary Glands - p. 677 247. SPECIMEN EXAMINATION, SALIVARY GLANDS - p. 679 248. Chapter 195: Specimen Examination and Staging Tools, Salivary Glands - p. 679 249. SECTION 7: JAW - p. 681 250. Chapter 196: Teeth - p. 681 251. CONGENITAL/GENETIC/HEREDITARY - p. 685 252. Chapter 197: Cherubism - p. 685 253. REACTIVE/INFECTIOUS - p. 687 254. Chapter 198: Tori - p. 687 255. Chapter 199: Osteomyelitis - p. 689 256. Chapter 200: Osteonecrosis - p. 693 257. Chapter 201: Cemento-Osseous Dysplasia - p. 697 258. Chapter 202: Fibrous Dysplasia - p. 699 259. Chapter 203: Paget Disease of Bone - p. 703 260. CYSTS - p. 707 261. Chapter 204: Simple Bone Cyst - p. 707 262. Chapter 205: Pseudocysts and Surgical Ciliated Cysts of Jaw - p. 709 263. Chapter 206: Periapical Cyst/Granuloma - p. 711 264. Chapter 207: Nasopalatine Duct Cyst - p. 713 265. Chapter 208: Dentigerous Cyst - p. 715 266. Chapter 209: Orthokeratinized Odontogenic Cyst - p. 719 267. Chapter 210: Lateral Periodontal Cyst - p. 721 268. Chapter 211: Calcifying Odontogenic Cyst - p. 723 269. Chapter 212: Glandular Odontogenic Cyst - p. 725 270. Chapter 213: Odontogenic Keratocyst - p. 727 271. BENIGN NEOPLASM - p. 731 272. Chapter 214: Adenomatoid Odontogenic Tumor - p. 731 273. Chapter 215: Squamous Odontogenic Tumor - p. 733 274. Chapter 216: Calcifying Epithelial Odontogenic Tumor - p. 735 275. Chapter 217: Ameloblastoma, Jaw - p. 737 276. Chapter 218: Odontoma (Complex and Compound) - p. 743 277. Chapter 219: Ameloblastic Fibroma/Fibroodontoma - p. 745 278. Chapter 220: Odontogenic Fibroma - p. 747 279. Chapter 221: Cementoblastoma - p. 749 280. Chapter 222: Odontogenic Myxoma - p. 751 281. Chapter 223: Central Giant Cell Granuloma - p. 753 282. Chapter 224: Ossifying Fibroma, Jaw - p. 755 283. Chapter 225: Juvenile Active Ossifying Fibroma - p. 759 284. Chapter 226: Osteoma - p. 763 285. Chapter 227: Osteoblastoma - p. 765 286. MALIGNANT NEOPLASM - p. 767 287. Chapter 228: Ameloblastic Carcinoma - p. 767 288. Chapter 229: Clear Cell Odontogenic Carcinoma - p. 769 289. Chapter 230: Ghost Cell Odontogenic Carcinoma - p. 771 290. Chapter 231: Ameloblastic Fibrosarcoma - p. 773 291. Chapter 232: Osteosarcoma, Jaw - p. 775 292. Chapter 233: Chondrosarcoma, Jaw - p. 779 293. Chapter 234: Plasma Cell Myeloma, Jaw - p. 785 294. SECTION 8: EAR AND TEMPORAL BONE - p. 787 295. Chapter 235: Ear - p. 787 296. CONGENITAL/GENETIC/HEREDITARY - p. 791 297. Chapter 236: Accessory Tragus - p. 791 298. Chapter 237: Encephalocele - p. 793 299. Chapter 238: First Branchial Cleft Anomaly - p. 795 300. INFECTIOUS - p. 799 301. Chapter 239: Otitis Media - p. 799 302. Chapter 240: Necrotizing Otitis Externa - p. 801 303. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 803 304. Chapter 241: Chondrodermatitis Nodularis Chronica Helicis - p. 803 305. Chapter 242: Otic Polyp - p. 805 306. Chapter 243: Relapsing Polychondritis - p. 807 307. DEGENERATIVE - p. 809 308. Chapter 244: Cystic Chondromalacia (Auricular Pseudocyst) - p. 809 309. Chapter 245: Otosclerosis - p. 811 310. METABOLIC - p. 813 311. Chapter 246: Gout - p. 813 312. REACTIVE - p. 815 313. Chapter 247: Exostosis - p. 815 314. Chapter 248: Keloid - p. 817 315. Chapter 249: Synovial Chondromatosis (Temporomandibular Joint) - p. 819 316. BENIGN NEOPLASM - p. 821 317. Chapter 250: Ceruminous Adenoma - p. 821 318. Chapter 251: Cholesteatoma - p. 825 319. Chapter 252: Jugulotympanic Paraganglioma - p. 829 320. Chapter 253: Vestibular Schwannoma - p. 835 321. Chapter 254: Meningioma, Ear and Temporal Bone - p. 839 322. Chapter 255: Epithelioid Hemangioma - p. 841 323. Chapter 256: Middle Ear Neuroendocrine Tumor - p. 843 324. Chapter 257: Endolymphatic Sac Tumor - p. 849 325. Chapter 258: Langerhans Cell Histiocytosis, Ear and Temporal Bone - p. 853 326. MALIGNANT NEOPLASM - p. 855 327. Chapter 259: Atypical Fibroxanthoma - p. 855 328. Chapter 260: Squamous Cell Carcinoma, Ear and Temporal Bone - p. 859 329. Chapter 261: Basal Cell Carcinoma - p. 863 330. Chapter 262: Merkel Cell Carcinoma - p. 865 331. Chapter 263: Dermatofibrosarcoma Protuberans - p. 869 332. Chapter 264: Ceruminous Adenocarcinoma - p. 873 333. Chapter 265: Rhabdomyosarcoma, Ear and Temporal Bone - p. 877 334. Chapter 266: Metastatic/Secondary Tumors, Ear and Temporal Bone - p. 881 335. SECTION 9: NECK (SOFT TISSUE AND LYMPH NODES) - p. 883 336. Chapter 267: Lymph Nodes - p. 883 337. CONGENITAL/GENETIC/HEREDITARY - p. 887 338. Chapter 268: Branchial Cleft Cyst - p. 887 339. Chapter 269: Dermoid Cyst - p. 893 340. Chapter 270: Cervical Thymic Cyst - p. 895 341. Chapter 271: Bronchogenic Cyst - p. 897 342. INFECTIOUS - p. 899 343. Chapter 272: Cat-Scratch Disease - p. 899 344. Chapter 273: Bacillary Angiomatosis - p. 903 345. Chapter 274: Mycobacterial Spindle Cell Pseudotumor - p. 905 346. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 907 347. Chapter 275: Sarcoidosis - p. 907 348. REACTIVE - p. 909 349. Chapter 276: Nodular Fasciitis - p. 909 350. BENIGN NEOPLASM - p. 911 351. Chapter 277: Lymphangioma, Neck - p. 911 352. Chapter 278: Lipoma - p. 913 353. Chapter 279: Spindle Cell Lipoma - p. 915 354. Chapter 280: Hibernoma - p. 917 355. Chapter 281: Lipoblastoma - p. 919 356. Chapter 282: Elastofibroma - p. 921 357. Chapter 283: Perineurioma - p. 923 358. Chapter 284: Fetal Rhabdomyoma - p. 927 359. Chapter 285: Nuchal-Type Fibroma - p. 931 360. Chapter 286: Branchioma (Ectopic Hamartomatous Thymoma) - p. 933 361. Chapter 287: Carotid Body Paraganglioma - p. 935 362. MALIGNANT NEOPLASM - p. 941 363. Chapter 288: Metastatic Cystic Squamous Cell Carcinoma - p. 941 364. Chapter 289: Synovial Sarcoma - p. 947 365. Chapter 290: Chordoma - p. 953 366. Chapter 291: Liposarcoma - p. 959 367. SECTION 10: THYROID GLAND - p. 963 368. Chapter 292: Thyroid Gland - p. 963 369. CONGENITAL/GENETIC/HEREDITARY - p. 967 370. Chapter 293: Thyroglossal Duct Cyst - p. 967 371. Chapter 294: Ectopic Thyroid Gland - p. 971 372. Chapter 295: Solid Cell Nests - p. 973 373. Chapter 296: Dyshormonogenetic Goiter - p. 975 374. INFECTIOUS - p. 979 375. Chapter 297: Infectious Thyroiditis - p. 979 376. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 983 377. Chapter 298: Palpation Thyroiditis - p. 983 378. Chapter 299: Subacute Granulomatous Thyroiditis (de Quervain) - p. 985 379. Chapter 300: Chronic Lymphocytic (Hashimoto) Thyroiditis - p. 991 380. Chapter 301: Graves Disease (Diffuse Hyperplasia) - p. 997 381. Chapter 302: Amyloid Goiter - p. 1003 382. Chapter 303: IgG4-Related Thyroiditis - p. 1007 383. REACTIVE - p. 1009 384. Chapter 304: Multinodular Hyperplasia - p. 1009 385. Chapter 305: Pigments and Crystals in Thyroid Gland - p. 1017 386. Chapter 306: Post Thyroid Biopsy Changes - p. 1019 387. Chapter 307: C-Cell Hyperplasia (Physiologic) - p. 1023 388. Chapter 308: Radiation Thyroiditis - p. 1025 389. BENIGN NEOPLASM - p. 1027 390. Chapter 309: Follicular Adenoma - p. 1027 391. Chapter 310: Follicular Adenoma With Papillary Architecture - p. 1033 392. Chapter 311: Oncocytic Follicular Adenoma - p. 1037 393. Chapter 312: Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclei - p. 1041 394. Chapter 313: Hyalinizing Trabecular Tumor - p. 1045 395. Chapter 314: Thyroid Teratoma - p. 1049 396. Chapter 315: Paraganglioma, Thyroid Gland - p. 1053 397. Chapter 316: Solitary Fibrous Tumor, Thyroid Gland - p. 1055 398. Chapter 317: Leiomyoma, Thyroid Gland - p. 1059 399. Chapter 318: Schwannoma, Thyroid Gland - p. 1061 400. Chapter 319: Langerhans Cell Histiocytosis, Thyroid Gland - p. 1063 401. Chapter 320: Ovarian Thyroid Tissue - p. 1067 402. MALIGNANT NEOPLASM - p. 1071 403. Chapter 321: Papillary Thyroid Carcinoma - p. 1071 404. Chapter 322: Follicular Thyroid Carcinoma - p. 1087 405. Chapter 323: Oncocytic Follicular Thyroid Carcinoma - p. 1099 406. Chapter 324: High-Grade Follicular-Derived Thyroid Carcinomas - p. 1105 407. Chapter 325: Undifferentiated (Anaplastic) Thyroid Carcinoma - p. 1113 408. Chapter 326: Medullary Thyroid Carcinoma - p. 1121 409. Chapter 327: Thyroblastoma - p. 1133 410. Chapter 328: Mucoepidermoid Carcinoma, Thyroid Gland - p. 1135 411. Chapter 329: Sclerosing Mucoepidermoid Carcinoma With Eosinophilia - p. 1139 412. Chapter 330: Cribriform Morular Thyroid Carcinoma - p. 1143 413. Chapter 331: Spindle Epithelial Tumor With Thymus-Like Elements - p. 1145 414. Chapter 332: Thymic Carcinoma Family Thyroid Tumors - p. 1149 415. Chapter 333: Angiosarcoma, Thyroid Gland - p. 1153 416. Chapter 334: Leiomyosarcoma, Thyroid Gland - p. 1157 417. Chapter 335: Malignant Peripheral Nerve Sheath Tumor, Thyroid Gland - p. 1161 418. Chapter 336: Follicular Dendritic Cell Sarcoma, Thyroid Gland - p. 1165 419. Chapter 337: Lymphoma, Thyroid Gland - p. 1169 420. Chapter 338: Metastatic/Secondary Tumors, Thyroid Gland - p. 1179 421. SPECIMEN EXAMINATION, THYROID GLAND - p. 1185 422. Chapter 339: Specimen Examination and Staging Tools, Thyroid Gland - p. 1185 423. SECTION 11: PARATHYROID GLANDS - p. 1187 424. Chapter 340: Parathyroid - p. 1187 425. NONNEOPLASTIC - p. 1191 426. Chapter 341: Parathyroid Hyperplasia - p. 1191 427. Chapter 342: Tertiary Hyperparathyroidism - p. 1199 428. Chapter 343: Chronic Parathyroiditis - p. 1200 429. BENIGN NEOPLASM - p. 1201 430. Chapter 344: Parathyroid Adenoma - p. 1201 431. MALIGNANT NEOPLASM - p. 1209 432. Chapter 345: Parathyroid Carcinoma - p. 1209 433. Chapter 346: Metastatic/Secondary Tumors, Parathyroid Glands - p. 1215 434. INDEX - p. 1217
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of head and neck pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Head and Neck is a one-stop reference for accurate, complete pathology reports—ideal as a day-to-day reference or as a reliable teaching resource.
Provides a clear framework for a better understanding of the clinical and histopathologic appearances of more than 325 new or evolving entities of the head and neck and endocrine organs
Features updates on recent changes in the field and current information from the AJCC Cancer Staging Manual, 8th Edition, and the World Health Organization Classification of Head and Neck Tumours, 5th Edition
Covers numerous new diagnostic entities, including intraductal carcinoma, sclerosing polycystic adenoma, microsecretory adenocarcinoma, adamantinoma-like Ewing sarcoma, SMARCB1- and SMARCA4-deficient carcinomas, and HPV-related multiphenotypic sinonasal carcinoma
Contains major updates on sinonasal tract, salivary gland, and odontogenic tumors; oropharyngeal squamous cell carcinoma and its correct classification and staging; the recent significant reclassification of neuroendocrine tumors; and changes in terminology and identification for head and neck soft tissue tumors
Suggests supporting studies in a realistic clinical context, with tables and immunohistochemical charts that assist with management decisions and prognostic outcome predictions
Features more than 3,200 images, including full-color drawings of head and neck anatomy, development pathway drawings, staging protocol illustrations, and genetic pathway graphics; radiologic images, clinical photographs, and gross images; and histology, histochemistry, immunohistochemistry, in situ hybridization, and molecular images; as well as more than 2,600 additional online-only images
Employs consistently templated chapters, bulleted content, key facts, and annotated images for quick, expert reference at the point of care
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedications - p. iii 6. Contributing Author - p. v 7. Preface - p. v 8. Acknowledgments - p. ix 9. Sections - p. xi 10. SECTION 1: NASAL CAVITY AND PARANASAL SINUSES - p. xiii 11. List of Tables - p. xiii 12. Chapter 1: Nose and Paranasal Sinuses - p. xiii 13. CONGENITAL/GENETIC/HEREDITARY - p. 5 14. Chapter 2: Nasal Neuroglial Heterotopia - p. 5 15. Chapter 3: Nasal Dermoid Cyst and Sinus - p. 7 16. INFECTIOUS - p. 9 17. Chapter 4: Allergic Fungal Sinusitis - p. 9 18. Chapter 5: Invasive Fungal Rhinosinusitis - p. 13 19. Chapter 6: Mycetoma - p. 15 20. Chapter 7: Rhinoscleroma - p. 16 21. Chapter 8: Rhinosporidiosis - p. 17 22. Chapter 9: Mycobacterium leprae Infection - p. 19 23. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 21 24. Chapter 10: Chronic Rhinosinusitis - p. 21 25. Chapter 11: Granulomatosis With Polyangiitis - p. 25 26. Chapter 12: Eosinophilic Angiocentric Fibrosis - p. 31 27. REACTIVE AND HAMARTOMAS - p. 35 28. Chapter 13: Sinonasal Inflammatory Polyp - p. 35 29. Chapter 14: Antrochoanal Polyp - p. 39 30. Chapter 15: Mucocele of Paranasal Sinus - p. 41 31. Chapter 16: Sinonasal Hamartoma - p. 43 32. Chapter 17: Nasal Chondromesenchymal Hamartoma - p. 49 33. Chapter 18: Extranodal Sinus Histiocytosis With Massive Lymphadenopathy - p. 51 34. Chapter 19: Myospherulosis - p. 55 35. BENIGN NEOPLASM - p. 57 36. Chapter 20: Sinonasal Papilloma - p. 57 37. Chapter 21: Pleomorphic Adenoma, Sinonasal Tract - p. 65 38. Chapter 22: Meningioma, Sinonasal Tract - p. 67 39. Chapter 23: Ameloblastoma, Sinonasal Tract - p. 71 40. Chapter 24: Ectopic Pituitary Neuroendocrine Tumor - p. 73 41. Chapter 25: Lobular Capillary Hemangioma (Pyogenic Granuloma) - p. 79 42. Chapter 26: Sinonasal Tract Angiofibroma - p. 83 43. Chapter 27: Schwannoma/Neurofibroma, Sinonasal Tract - p. 87 44. Chapter 28: Leiomyoma and Smooth Muscle Tumors of Uncertain Malignant Potential - p. 91 45. Chapter 29: Fibromatosis/Desmoid-Type Fibromatosis - p. 95 46. Chapter 30: Solitary Fibrous Tumor, Sinonasal Tract - p. 97 47. BORDERLINE NEOPLASM - p. 101 48. Chapter 31: Glomangiopericytoma - p. 101 49. MALIGNANT NEOPLASM - p. 105 50. Chapter 32: Squamous Cell Carcinoma, Sinonasal Tract - p. 105 51. Chapter 33: NUT Carcinoma - p. 113 52. Chapter 34: SWI/SNF Complex-Deficient Sinonasal Carcinomas - p. 115 53. Chapter 35: Lymphoepithelial Carcinoma, Sinonasal Tract - p. 119 54. Chapter 36: Sinonasal Undifferentiated Carcinoma - p. 121 55. Chapter 37: Teratocarcinosarcoma - p. 127 56. Chapter 38: HPV-Related Multiphenotypic Sinonasal Carcinoma - p. 132 57. Chapter 39: Sinonasal Adenocarcinoma, Intestinal Type - p. 137 58. Chapter 40: Sinonasal Nonintestinal-Nonsalivary Adenocarcinoma - p. 143 59. Chapter 41: Sinonasal Renal Cell-Like Adenocarcinoma - p. 151 60. Chapter 42: Olfactory Neuroblastoma - p. 153 61. Chapter 43: Sinonasal Neuroendocrine Carcinoma - p. 163 62. Chapter 44: Mucosal Melanoma, Sinonasal Tract - p. 169 63. Chapter 45: Alveolar Rhabdomyosarcoma, Sinonasal Tract - p. 175 64. Chapter 46: Ewing Sarcoma, Including Sinonasal Adamantinoma-Like - p. 181 65. Chapter 47: Biphenotypic Sinonasal Sarcoma - p. 187 66. Chapter 48: Leiomyosarcoma, Sinonasal Tract - p. 191 67. Chapter 49: Malignant Peripheral Nerve Sheath Tumor, Sinonasal Tract - p. 197 68. Chapter 50: Fibrosarcoma, Sinonasal Tract - p. 201 69. Chapter 51: Angiosarcoma, Sinonasal Tract - p. 205 70. Chapter 52: Mesenchymal Chondrosarcoma, Sinonasal Tract - p. 209 71. Chapter 53: Undifferentiated Pleomorphic Sarcoma, Sinonasal Tract - p. 211 72. Chapter 54: Extranodal NK-/T-Cell Lymphoma, Nasal Type - p. 215 73. Chapter 55: Metastatic/Secondary Tumors, Sinonasal Tract - p. 221 74. SPECIMEN EXAMINATION, NASAL CAVITY & PARANASAL SINUSES - p. 223 75. Chapter 56: Specimen Examination and Staging Tools, Oropharynx - p. 223 76. Chapter 57: Specimen Examination and Staging Tools, Nasopharynx - p. 227 77. SECTION 2: PHARYNX (NASAL, HYPO-) - p. 231 78. Chapter 58: Pharynx - p. 231 79. CONGENITAL/GENETIC/HEREDITARY - p. 235 80. Chapter 59: Tornwaldt Cyst - p. 235 81. Chapter 60: Rathke Cleft Cyst - p. 236 82. BENIGN NEOPLASM - p. 237 83. Chapter 61: Dermoid - p. 237 84. MALIGNANT NEOPLASM - p. 239 85. Chapter 62: Low-Grade Nasopharyngeal Papillary Adenocarcinoma - p. 239 86. Chapter 63: Nasopharyngeal Carcinoma, Nonkeratinizing Types - p. 243 87. Chapter 64: Nasopharyngeal Carcinoma, Keratinizing Type - p. 253 88. Chapter 65: Nasopharyngeal Carcinoma, Basaloid Squamous Cell Carcinoma - p. 255 89. Chapter 66: Diffuse Large B-Cell Lymphoma NOS - p. 259 90. SECTION 3: LARYNX AND TRACHEA - p. 263 91. Chapter 67: Larynx - p. 263 92. CONGENITAL/GENETIC/HEREDITARY - p. 267 93. Chapter 68: Laryngocele and Laryngeal Cysts - p. 267 94. Chapter 69: Tracheopathia Osteoplastica - p. 269 95. INFECTIOUS - p. 271 96. Chapter 70: Laryngitis: Viral, Bacterial, Fungal - p. 271 97. REACTIVE - p. 275 98. Chapter 71: Vocal Cord Nodules and Polyps - p. 275 99. Chapter 72: Reactive Epithelial Changes - p. 279 100. Chapter 73: Contact Ulcer - p. 283 101. Chapter 74: Amyloid (Amyloidoma) - p. 285 102. BENIGN NEOPLASM - p. 287 103. Chapter 75: Squamous Papilloma - p. 287 104. Chapter 76: Granular Cell Tumor, Larynx - p. 291 105. Chapter 77: Adult Rhabdomyoma - p. 293 106. Chapter 78: Inflammatory Myofibroblastic Tumor - p. 295 107. Chapter 79: Paraganglioma, Larynx - p. 299 108. Chapter 80: Chondroma - p. 301 109. BORDERLINE NEOPLASM - p. 303 110. Chapter 81: EBV-Associated Smooth Muscle Tumor - p. 303 111. MALIGNANT NEOPLASM - p. 305 112. Chapter 82: Keratinizing Dysplasia and Carcinoma In Situ - p. 305 113. Chapter 83: Conventional Squamous Cell Carcinoma - p. 313 114. Chapter 84: Verrucous Carcinoma - p. 321 115. Chapter 85: Spindle Cell Squamous Cell Carcinoma - p. 325 116. Chapter 86: Papillary Squamous Cell Carcinoma - p. 331 117. Chapter 87: Basaloid Squamous Cell Carcinoma - p. 335 118. Chapter 88: Adenosquamous Carcinoma - p. 339 119. Chapter 89: Neuroendocrine Neoplasms, Larynx - p. 343 120. Chapter 90: Chondrosarcoma - p. 353 121. Chapter 91: Metastatic/Secondary Tumors, Larynx and Trachea - p. 357 122. SPECIMEN EXAMINATION, LARYNX - p. 359 123. Chapter 92: Specimen Examination and Staging Tools, Larynx and Trachea - p. 359 124. SECTION 4: ORAL CAVITY - p. 361 125. Chapter 93: Tongue - p. 361 126. Chapter 94: Oral Mucosae - p. 365 127. CONGENITAL/GENETIC/HEREDITARY - p. 367 128. Chapter 95: Ectopic (Lingual) Thyroid - p. 367 129. Chapter 96: White Sponge Nevus - p. 369 130. INFECTIOUS - p. 371 131. Chapter 97: Multifocal Epithelial Hyperplasia (Heck Disease) - p. 371 132. Chapter 98: Oral Hairy Leukoplakia - p. 373 133. Chapter 99: Oral Infections - p. 375 134. Chapter 100: Oral Syphilis - p. 379 135. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 383 136. Chapter 101: Aphthous Stomatitis - p. 383 137. Chapter 102: Pemphigus Vulgaris - p. 389 138. Chapter 103: Mucous Membrane Pemphigoid - p. 391 139. Chapter 104: Oral Lichen Planus - p. 393 140. Chapter 105: Erythema Multiforme - p. 397 141. Chapter 106: Lupus Erythematosus - p. 399 142. REACTIVE - p. 403 143. Chapter 107: Frictional Hyperkeratosis - p. 403 144. Chapter 108: Pseudoepitheliomatous Hyperplasia - p. 404 145. Chapter 109: Necrotizing Sialometaplasia - p. 405 146. Chapter 110: Traumatic Ulcerative Granuloma With Stromal Eosinophilia - p. 407 147. Chapter 111: Giant Cell Fibroma - p. 409 148. Chapter 112: Amalgam Tattoo - p. 410 149. Chapter 113: Tobacco Changes - p. 411 150. Chapter 114: Parulis - p. 413 151. NONNEOPLASTIC LESIONS - p. 414 152. Chapter 115: Fordyce Granules - p. 414 153. Chapter 116: Mucocele and Ranula - p. 415 154. Chapter 117: Verruciform Xanthoma - p. 417 155. Chapter 118: Hairy Tongue - p. 418 156. Chapter 119: Geographic Tongue - p. 419 157. Chapter 120: Juxtaoral Organ of Chievitz - p. 421 158. Chapter 121: Heterotopic Salivary Glands - p. 422 159. BENIGN NEOPLASM - p. 423 160. Chapter 122: Squamous Papilloma (Including Verruca and Condyloma) - p. 423 161. Chapter 123: Fibroma, Oral Cavity - p. 427 162. Chapter 124: Pyogenic Granuloma - p. 429 163. Chapter 125: Peripheral Giant Cell Granuloma - p. 431 164. Chapter 126: Peripheral Ossifying Fibroma - p. 433 165. Chapter 127: Mucosal Neuroma - p. 435 166. Chapter 128: Solitary Circumscribed Neuroma - p. 437 167. Chapter 129: Acquired Melanocytic Nevus - p. 439 168. Chapter 130: Melanoacanthoma - p. 443 169. Chapter 131: Oral Lymphangioma - p. 444 170. Chapter 132: Teratoma, Oral Cavity - p. 445 171. BORDERLINE NEOPLASM - p. 447 172. Chapter 133: Congenital Granular Cell Epulis - p. 447 173. Chapter 134: Granular Cell Tumor, Oral Cavity - p. 449 174. Chapter 135: Melanotic Neuroectodermal Tumor of Infancy - p. 453 175. Chapter 136: Ectomesenchymal Chondromyxoid Tumor - p. 455 176. Chapter 137: GLI1-Altered Soft Tissue Tumor - p. 459 177. MALIGNANT NEOPLASM - p. 461 178. Chapter 138: Dysplasia and Carcinoma In Situ - p. 461 179. Chapter 139: Proliferative Verrucous Leukoplakia - p. 467 180. Chapter 140: Squamous Cell Carcinoma, Oral Cavity - p. 469 181. Chapter 141: Mucosal Melanoma, Oral Cavity - p. 475 182. Chapter 142: Extraskeletal Myxoid Chondrosarcoma - p. 479 183. Chapter 143: Angiosarcoma, Oral Cavity - p. 481 184. Chapter 144: Kaposi Sarcoma, Oral Cavity - p. 483 185. Chapter 145: Metastatic/Secondary Tumors: Oral Cavity; Jaw - p. 485 186. SPECIMEN EXAMINATION, LIP AND ORAL CAVITY - p. 487 187. Chapter 146: Specimen Examination and Staging Tools, Lip and Oral Cavity - p. 487 188. SECTION 5: OROPHARYNX - p. 489 189. INFECTIOUS - p. 489 190. Chapter 147: Infectious Mononucleosis - p. 489 191. Chapter 148: HIV Infection of Tonsils and Adenoids - p. 495 192. REACTIVE - p. 499 193. Chapter 149: Lymphangiomatous Polyp - p. 499 194. MALIGNANT NEOPLASM - p. 501 195. Chapter 150: Oropharyngeal Carcinoma - p. 501 196. SECTION 6: SALIVARY GLANDS - p. 505 197. Chapter 151: Major Salivary Glands - p. 505 198. INFECTIOUS - p. 509 199. Chapter 152: HIV Salivary Gland Disease - p. 509 200. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 511 201. Chapter 153: Benign Lymphoepithelial Cyst - p. 511 202. Chapter 154: Benign Lymphoepithelial Lesion - p. 513 203. Chapter 155: Sjögren Syndrome - p. 515 204. Chapter 156: IgG4-Related Salivary Gland Disease - p. 519 205. REACTIVE - p. 523 206. Chapter 157: Oncocytosis (Oncocytic Hyperplasia) - p. 523 207. Chapter 158: Sialolithiasis - p. 524 208. BENIGN NEOPLASM - p. 525 209. Chapter 159: Pleomorphic Adenoma - p. 525 210. Chapter 160: Basal Cell Adenoma - p. 535 211. Chapter 161: Myoepithelioma - p. 539 212. Chapter 162: Warthin Tumor (Papillary Cystadenoma Lymphomatosum) - p. 543 213. Chapter 163: Oncocytoma - p. 547 214. Chapter 164: Canalicular Adenoma - p. 553 215. Chapter 165: Cystadenoma - p. 555 216. Chapter 166: Ductal Papillomas - p. 557 217. Chapter 167: Salivary Gland Adenoma: Lymphadenoma, Sebaceous Lymphadenoma, and Sebaceous Adenoma - p. 561 218. Chapter 168: Sclerosing Polycystic Adenoma - p. 563 219. Chapter 169: Keratocystoma - p. 565 220. Chapter 170: Sialolipoma - p. 566 221. Chapter 171: Hemangioma, Parotid Gland - p. 567 222. BORDERLINE NEOPLASM - p. 569 223. Chapter 172: Sialoblastoma - p. 569 224. MALIGNANT NEOPLASM - p. 573 225. Chapter 173: Mucoepidermoid Carcinoma, Salivary - p. 573 226. Chapter 174: Adenoid Cystic Carcinoma - p. 583 227. Chapter 175: Acinic Cell Carcinoma - p. 591 228. Chapter 176: Secretory Carcinoma, Salivary Gland - p. 599 229. Chapter 177: Microsecretory Adenocarcinoma - p. 603 230. Chapter 178: Polymorphous Adenocarcinoma, Low-Grade Subtype - p. 605 231. Chapter 179: Polymorphous Adenocarcinoma, Cribriform Subtype - p. 611 232. Chapter 180: Hyalinizing Clear Cell Carcinoma - p. 613 233. Chapter 181: Basal Cell Adenocarcinoma - p. 619 234. Chapter 182: Intraductal Carcinoma - p. 623 235. Chapter 183: Salivary Duct Carcinoma - p. 625 236. Chapter 184: Myoepithelial Carcinoma - p. 635 237. Chapter 185: Epithelial-Myoepithelial Carcinoma - p. 639 238. Chapter 186: Carcinoma Ex-Pleomorphic Adenoma - p. 645 239. Chapter 187: Mucinous Adenocarcinoma - p. 655 240. Chapter 188: Sclerosing Microcystic Adenocarcinoma - p. 659 241. Chapter 189: Lymphoepithelial Carcinoma, Salivary Gland - p. 661 242. Chapter 190: Sebaceous Carcinoma and Sebaceous Lymphadenocarcinoma - p. 667 243. Chapter 191: Adenocarcinoma, Not Otherwise Specified - p. 669 244. Chapter 192: Small Cell Neuroendocrine Carcinoma, Salivary Gland - p. 671 245. Chapter 193: Lymphoma, Salivary Gland - p. 675 246. Chapter 194: Metastatic/Secondary Tumors, Salivary Glands - p. 677 247. SPECIMEN EXAMINATION, SALIVARY GLANDS - p. 679 248. Chapter 195: Specimen Examination and Staging Tools, Salivary Glands - p. 679 249. SECTION 7: JAW - p. 681 250. Chapter 196: Teeth - p. 681 251. CONGENITAL/GENETIC/HEREDITARY - p. 685 252. Chapter 197: Cherubism - p. 685 253. REACTIVE/INFECTIOUS - p. 687 254. Chapter 198: Tori - p. 687 255. Chapter 199: Osteomyelitis - p. 689 256. Chapter 200: Osteonecrosis - p. 693 257. Chapter 201: Cemento-Osseous Dysplasia - p. 697 258. Chapter 202: Fibrous Dysplasia - p. 699 259. Chapter 203: Paget Disease of Bone - p. 703 260. CYSTS - p. 707 261. Chapter 204: Simple Bone Cyst - p. 707 262. Chapter 205: Pseudocysts and Surgical Ciliated Cysts of Jaw - p. 709 263. Chapter 206: Periapical Cyst/Granuloma - p. 711 264. Chapter 207: Nasopalatine Duct Cyst - p. 713 265. Chapter 208: Dentigerous Cyst - p. 715 266. Chapter 209: Orthokeratinized Odontogenic Cyst - p. 719 267. Chapter 210: Lateral Periodontal Cyst - p. 721 268. Chapter 211: Calcifying Odontogenic Cyst - p. 723 269. Chapter 212: Glandular Odontogenic Cyst - p. 725 270. Chapter 213: Odontogenic Keratocyst - p. 727 271. BENIGN NEOPLASM - p. 731 272. Chapter 214: Adenomatoid Odontogenic Tumor - p. 731 273. Chapter 215: Squamous Odontogenic Tumor - p. 733 274. Chapter 216: Calcifying Epithelial Odontogenic Tumor - p. 735 275. Chapter 217: Ameloblastoma, Jaw - p. 737 276. Chapter 218: Odontoma (Complex and Compound) - p. 743 277. Chapter 219: Ameloblastic Fibroma/Fibroodontoma - p. 745 278. Chapter 220: Odontogenic Fibroma - p. 747 279. Chapter 221: Cementoblastoma - p. 749 280. Chapter 222: Odontogenic Myxoma - p. 751 281. Chapter 223: Central Giant Cell Granuloma - p. 753 282. Chapter 224: Ossifying Fibroma, Jaw - p. 755 283. Chapter 225: Juvenile Active Ossifying Fibroma - p. 759 284. Chapter 226: Osteoma - p. 763 285. Chapter 227: Osteoblastoma - p. 765 286. MALIGNANT NEOPLASM - p. 767 287. Chapter 228: Ameloblastic Carcinoma - p. 767 288. Chapter 229: Clear Cell Odontogenic Carcinoma - p. 769 289. Chapter 230: Ghost Cell Odontogenic Carcinoma - p. 771 290. Chapter 231: Ameloblastic Fibrosarcoma - p. 773 291. Chapter 232: Osteosarcoma, Jaw - p. 775 292. Chapter 233: Chondrosarcoma, Jaw - p. 779 293. Chapter 234: Plasma Cell Myeloma, Jaw - p. 785 294. SECTION 8: EAR AND TEMPORAL BONE - p. 787 295. Chapter 235: Ear - p. 787 296. CONGENITAL/GENETIC/HEREDITARY - p. 791 297. Chapter 236: Accessory Tragus - p. 791 298. Chapter 237: Encephalocele - p. 793 299. Chapter 238: First Branchial Cleft Anomaly - p. 795 300. INFECTIOUS - p. 799 301. Chapter 239: Otitis Media - p. 799 302. Chapter 240: Necrotizing Otitis Externa - p. 801 303. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 803 304. Chapter 241: Chondrodermatitis Nodularis Chronica Helicis - p. 803 305. Chapter 242: Otic Polyp - p. 805 306. Chapter 243: Relapsing Polychondritis - p. 807 307. DEGENERATIVE - p. 809 308. Chapter 244: Cystic Chondromalacia (Auricular Pseudocyst) - p. 809 309. Chapter 245: Otosclerosis - p. 811 310. METABOLIC - p. 813 311. Chapter 246: Gout - p. 813 312. REACTIVE - p. 815 313. Chapter 247: Exostosis - p. 815 314. Chapter 248: Keloid - p. 817 315. Chapter 249: Synovial Chondromatosis (Temporomandibular Joint) - p. 819 316. BENIGN NEOPLASM - p. 821 317. Chapter 250: Ceruminous Adenoma - p. 821 318. Chapter 251: Cholesteatoma - p. 825 319. Chapter 252: Jugulotympanic Paraganglioma - p. 829 320. Chapter 253: Vestibular Schwannoma - p. 835 321. Chapter 254: Meningioma, Ear and Temporal Bone - p. 839 322. Chapter 255: Epithelioid Hemangioma - p. 841 323. Chapter 256: Middle Ear Neuroendocrine Tumor - p. 843 324. Chapter 257: Endolymphatic Sac Tumor - p. 849 325. Chapter 258: Langerhans Cell Histiocytosis, Ear and Temporal Bone - p. 853 326. MALIGNANT NEOPLASM - p. 855 327. Chapter 259: Atypical Fibroxanthoma - p. 855 328. Chapter 260: Squamous Cell Carcinoma, Ear and Temporal Bone - p. 859 329. Chapter 261: Basal Cell Carcinoma - p. 863 330. Chapter 262: Merkel Cell Carcinoma - p. 865 331. Chapter 263: Dermatofibrosarcoma Protuberans - p. 869 332. Chapter 264: Ceruminous Adenocarcinoma - p. 873 333. Chapter 265: Rhabdomyosarcoma, Ear and Temporal Bone - p. 877 334. Chapter 266: Metastatic/Secondary Tumors, Ear and Temporal Bone - p. 881 335. SECTION 9: NECK (SOFT TISSUE AND LYMPH NODES) - p. 883 336. Chapter 267: Lymph Nodes - p. 883 337. CONGENITAL/GENETIC/HEREDITARY - p. 887 338. Chapter 268: Branchial Cleft Cyst - p. 887 339. Chapter 269: Dermoid Cyst - p. 893 340. Chapter 270: Cervical Thymic Cyst - p. 895 341. Chapter 271: Bronchogenic Cyst - p. 897 342. INFECTIOUS - p. 899 343. Chapter 272: Cat-Scratch Disease - p. 899 344. Chapter 273: Bacillary Angiomatosis - p. 903 345. Chapter 274: Mycobacterial Spindle Cell Pseudotumor - p. 905 346. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 907 347. Chapter 275: Sarcoidosis - p. 907 348. REACTIVE - p. 909 349. Chapter 276: Nodular Fasciitis - p. 909 350. BENIGN NEOPLASM - p. 911 351. Chapter 277: Lymphangioma, Neck - p. 911 352. Chapter 278: Lipoma - p. 913 353. Chapter 279: Spindle Cell Lipoma - p. 915 354. Chapter 280: Hibernoma - p. 917 355. Chapter 281: Lipoblastoma - p. 919 356. Chapter 282: Elastofibroma - p. 921 357. Chapter 283: Perineurioma - p. 923 358. Chapter 284: Fetal Rhabdomyoma - p. 927 359. Chapter 285: Nuchal-Type Fibroma - p. 931 360. Chapter 286: Branchioma (Ectopic Hamartomatous Thymoma) - p. 933 361. Chapter 287: Carotid Body Paraganglioma - p. 935 362. MALIGNANT NEOPLASM - p. 941 363. Chapter 288: Metastatic Cystic Squamous Cell Carcinoma - p. 941 364. Chapter 289: Synovial Sarcoma - p. 947 365. Chapter 290: Chordoma - p. 953 366. Chapter 291: Liposarcoma - p. 959 367. SECTION 10: THYROID GLAND - p. 963 368. Chapter 292: Thyroid Gland - p. 963 369. CONGENITAL/GENETIC/HEREDITARY - p. 967 370. Chapter 293: Thyroglossal Duct Cyst - p. 967 371. Chapter 294: Ectopic Thyroid Gland - p. 971 372. Chapter 295: Solid Cell Nests - p. 973 373. Chapter 296: Dyshormonogenetic Goiter - p. 975 374. INFECTIOUS - p. 979 375. Chapter 297: Infectious Thyroiditis - p. 979 376. INFLAMMATORY-IMMUNE DYSFUNCTION - p. 983 377. Chapter 298: Palpation Thyroiditis - p. 983 378. Chapter 299: Subacute Granulomatous Thyroiditis (de Quervain) - p. 985 379. Chapter 300: Chronic Lymphocytic (Hashimoto) Thyroiditis - p. 991 380. Chapter 301: Graves Disease (Diffuse Hyperplasia) - p. 997 381. Chapter 302: Amyloid Goiter - p. 1003 382. Chapter 303: IgG4-Related Thyroiditis - p. 1007 383. REACTIVE - p. 1009 384. Chapter 304: Multinodular Hyperplasia - p. 1009 385. Chapter 305: Pigments and Crystals in Thyroid Gland - p. 1017 386. Chapter 306: Post Thyroid Biopsy Changes - p. 1019 387. Chapter 307: C-Cell Hyperplasia (Physiologic) - p. 1023 388. Chapter 308: Radiation Thyroiditis - p. 1025 389. BENIGN NEOPLASM - p. 1027 390. Chapter 309: Follicular Adenoma - p. 1027 391. Chapter 310: Follicular Adenoma With Papillary Architecture - p. 1033 392. Chapter 311: Oncocytic Follicular Adenoma - p. 1037 393. Chapter 312: Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclei - p. 1041 394. Chapter 313: Hyalinizing Trabecular Tumor - p. 1045 395. Chapter 314: Thyroid Teratoma - p. 1049 396. Chapter 315: Paraganglioma, Thyroid Gland - p. 1053 397. Chapter 316: Solitary Fibrous Tumor, Thyroid Gland - p. 1055 398. Chapter 317: Leiomyoma, Thyroid Gland - p. 1059 399. Chapter 318: Schwannoma, Thyroid Gland - p. 1061 400. Chapter 319: Langerhans Cell Histiocytosis, Thyroid Gland - p. 1063 401. Chapter 320: Ovarian Thyroid Tissue - p. 1067 402. MALIGNANT NEOPLASM - p. 1071 403. Chapter 321: Papillary Thyroid Carcinoma - p. 1071 404. Chapter 322: Follicular Thyroid Carcinoma - p. 1087 405. Chapter 323: Oncocytic Follicular Thyroid Carcinoma - p. 1099 406. Chapter 324: High-Grade Follicular-Derived Thyroid Carcinomas - p. 1105 407. Chapter 325: Undifferentiated (Anaplastic) Thyroid Carcinoma - p. 1113 408. Chapter 326: Medullary Thyroid Carcinoma - p. 1121 409. Chapter 327: Thyroblastoma - p. 1133 410. Chapter 328: Mucoepidermoid Carcinoma, Thyroid Gland - p. 1135 411. Chapter 329: Sclerosing Mucoepidermoid Carcinoma With Eosinophilia - p. 1139 412. Chapter 330: Cribriform Morular Thyroid Carcinoma - p. 1143 413. Chapter 331: Spindle Epithelial Tumor With Thymus-Like Elements - p. 1145 414. Chapter 332: Thymic Carcinoma Family Thyroid Tumors - p. 1149 415. Chapter 333: Angiosarcoma, Thyroid Gland - p. 1153 416. Chapter 334: Leiomyosarcoma, Thyroid Gland - p. 1157 417. Chapter 335: Malignant Peripheral Nerve Sheath Tumor, Thyroid Gland - p. 1161 418. Chapter 336: Follicular Dendritic Cell Sarcoma, Thyroid Gland - p. 1165 419. Chapter 337: Lymphoma, Thyroid Gland - p. 1169 420. Chapter 338: Metastatic/Secondary Tumors, Thyroid Gland - p. 1179 421. SPECIMEN EXAMINATION, THYROID GLAND - p. 1185 422. Chapter 339: Specimen Examination and Staging Tools, Thyroid Gland - p. 1185 423. SECTION 11: PARATHYROID GLANDS - p. 1187 424. Chapter 340: Parathyroid - p. 1187 425. NONNEOPLASTIC - p. 1191 426. Chapter 341: Parathyroid Hyperplasia - p. 1191 427. Chapter 342: Tertiary Hyperparathyroidism - p. 1199 428. Chapter 343: Chronic Parathyroiditis - p. 1200 429. BENIGN NEOPLASM - p. 1201 430. Chapter 344: Parathyroid Adenoma - p. 1201 431. MALIGNANT NEOPLASM - p. 1209 432. Chapter 345: Parathyroid Carcinoma - p. 1209 433. Chapter 346: Metastatic/Secondary Tumors, Parathyroid Glands - p. 1215 434. INDEX - p. 1217
