This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of thoracic pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Thoracic is a one-stop reference for accurate, rapid, and complete pathology reports—ideal as a day-to-day reference or as a reliable training resource.
Provides a clear framework for a better understanding of the clinical and histopathologic appearances of pulmonary, pleural, and mediastinal entities
Features an updated chapter on severe acute respiratory syndrome (SARS) pneumonia with current knowledge, statistics, and pathophysiology on COVID-19, including new images that encompass the radiology, gross pathology, and histopathology of the disease
Includes updated criteria, terminology, and classifications for a wide range of tumors from the 2021 World Health Organization Classification of Tumors of the Lung, Pleura, Thymus and Heart, reflecting changes to currently used terminologies for adenocarcinoma, squamous cell carcinoma, neuroendocrine tumors, mesothelioma, soft tissue tumors, benign tumors, and more
Covers the recent explosion of molecular genetic information, including new Molecular Pathology sections with new information on the genetic underpinnings of diseases
Specifies genetic mutation types associated with each tumor and covers numerous types of molecular tests, including next-generation sequencing studies and how the specific genetic alterations are used to differentiate disease and aid in diagnosis
Features over 3,900 high-quality images, including histologic images, gross pathology images, radiologic images, and full-color illustrations as well as more than 750 additional online-only images to help practicing and in-training pathologists reach a confident diagnosis
Contains multiple recent consensus clinical practice guidelines for thoracic disease diagnosis, including those for molecular genetic testing and predictive biomarker testing from the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology
Employs consistently templated chapters, bulleted content, key facts, and annotated images for quick, expert reference at the point of care
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedications - p. iii 6. Preface - p. v 7. Acknowledgments - p. vii 8. Sections - p. ix 9. Part I: Lung - p. xi 10. SECTION 1: NEOPLASMS, BENIGN - p. xi 11. List of Tables - p. xi 12. Chapter 1: Congenital Peribronchial Myofibroblastic Tumor - p. xi 13. Chapter 2: Fetal Lung Interstitial Tumor - p. 5 14. Chapter 3: Mucous Gland Adenoma - p. 7 15. Chapter 4: Ciliated Muconodular Papillary Tumor/Bronchiolar Adenoma - p. 11 16. Chapter 5: Alveolar Adenoma - p. 13 17. Chapter 6: Sclerosing Pneumocytoma - p. 17 18. Chapter 7: Cartilaginous Hamartoma - p. 23 19. Chapter 8: Endobronchial Lipoma - p. 27 20. Chapter 9: Pulmonary Adenofibroma/Adenomyoma - p. 29 21. Chapter 10: Glomus Tumor - p. 33 22. Chapter 11: Pulmonary Paraganglioma - p. 35 23. Chapter 12: Pulmonary Meningioma - p. 39 24. Chapter 13: Minute Pulmonary Meningothelial-Like Nodule - p. 43 25. Chapter 14: Granular Cell Tumor - p. 47 26. Chapter 15: Langerhans Cell Histiocytosis - p. 49 27. Chapter 16: Erdheim-Chester Disease - p. 53 28. Chapter 17: Pulmonary PEComa (Clear Cell Sugar Tumor) - p. 57 29. Chapter 18: Lymphangioleiomyomatosis - p. 61 30. SECTION 2: OTHER RARE TUMORS AND BENIGN PSEUDOTUMORAL CONDITIONS - p. 65 31. Chapter 19: Inflammatory Myofibroblastic Tumor - p. 65 32. Chapter 20: Intrapulmonary Thymoma - p. 71 33. Chapter 21: Juvenile Xanthogranuloma - p. 75 34. Chapter 22: Hyalinizing Granuloma - p. 79 35. Chapter 23: Metastatic/Dendriform Calcification - p. 83 36. Chapter 24: Lipoid Pneumonia - p. 87 37. Chapter 25: Placental Transmogrification - p. 89 38. Chapter 26: Rosai-Dorfman Disease - p. 93 39. Chapter 27: Epithelioid Hemangioma - p. 97 40. SECTION 3: NEOPLASMS, MALIGNANT, PRIMARY - p. 99 41. ADENOCARCINOMA - p. 99 42. Chapter 28: Overview of Malignant Epithelial Neoplasms of Lung - p. 99 43. Chapter 29: Conventional Adenocarcinoma - p. 105 44. Chapter 30: Lepidic-Predominant Adenocarcinoma - p. 117 45. ADENOCARCINOMA VARIANTS - p. 119 46. Chapter 31: Invasive Mucinous Adenocarcinoma - p. 119 47. Chapter 32: Colloid Adenocarcinoma - p. 123 48. Chapter 33: Fetal Adenocarcinoma - p. 127 49. Chapter 34: Enteric-Type Adenocarcinoma - p. 131 50. Chapter 35: Other Adenocarcinoma Variants - p. 133 51. Chapter 36: Adenosquamous Carcinoma - p. 137 52. SQUAMOUS CELL CARCINOMA - p. 141 53. Chapter 37: Conventional Squamous Cell Carcinoma - p. 141 54. Chapter 38: Basaloid/Small Cell Variant of Squamous Cell Carcinoma - p. 147 55. Chapter 39: Lymphoepithelioma-Like Carcinoma - p. 151 56. NEUROENDOCRINE CARCINOMA AND PRECURSOR LESIONS - p. 155 57. Chapter 40: Overview of Neuroendocrine Neoplasms - p. 155 58. Chapter 41: Pulmonary Tumorlet and Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia - p. 159 59. Chapter 42: Low-Grade Neuroendocrine Carcinoma (Typical Carcinoid Tumor) - p. 161 60. Chapter 43: Intermediate-Grade Neuroendocrine Carcinoma (Atypical Carcinoid Tumor) - p. 167 61. Chapter 44: High-Grade Neuroendocrine Carcinoma, Small Cell Type - p. 171 62. Chapter 45: High-Grade Neuroendocrine Carcinoma, Large Cell Type - p. 175 63. POORLY DIFFERENTIATED NON-SMALL CELL CARCINOMAS - p. 179 64. Chapter 46: Overview of Poorly Differentiated Non-Small Cell Carcinomas - p. 179 65. Chapter 47: Large Cell Carcinoma - p. 181 66. Chapter 48: Pleomorphic Carcinoma - p. 183 67. Chapter 49: Spindle Cell Carcinoma - p. 187 68. Chapter 50: Carcinosarcoma - p. 191 69. Chapter 51: Pulmonary Blastoma - p. 195 70. Chapter 52: SMARCA4-Deficient Undifferentiated Tumors - p. 199 71. Chapter 53: NUT Carcinoma - p. 203 72. SALIVARY GLAND-TYPE TUMORS - p. 205 73. Chapter 54: Adenoid Cystic Carcinoma - p. 205 74. Chapter 55: Mucoepidermoid Carcinoma of Lung - p. 211 75. Chapter 56: Epithelial-Myoepithelial Carcinoma - p. 217 76. Chapter 57: Acinic Cell Carcinoma - p. 221 77. Chapter 58: Mixed Tumor (Pleomorphic Adenoma) - p. 225 78. Chapter 59: Myoepithelial Carcinoma - p. 229 79. MESENCHYMAL NEOPLASMS - p. 233 80. Chapter 60: Pleuropulmonary Blastoma - p. 233 81. Chapter 61: Primary Pulmonary Myxoid Sarcoma - p. 237 82. Chapter 62: Intrapulmonary Solitary Fibrous Tumor - p. 239 83. Chapter 63: Leiomyosarcoma of Lung - p. 243 84. Chapter 64: Intrapulmonary Synovial Sarcoma - p. 247 85. Chapter 65: Malignant Peripheral Nerve Sheath Tumor of Lung - p. 253 86. Chapter 66: Osteosarcoma - p. 257 87. Chapter 67: Chondrosarcoma - p. 261 88. Chapter 68: Epithelioid Hemangioendothelioma of Lung - p. 265 89. Chapter 69: Angiosarcoma of Lung - p. 273 90. Chapter 70: Kaposi Sarcoma - p. 277 91. Chapter 71: Intimal Sarcoma - p. 281 92. LYMPHOPROLIFERATIVE DISORDERS - p. 285 93. Chapter 72: Benign Pulmonary Lymphoid Lesions - p. 285 94. Chapter 73: Pulmonary BALT Lymphoma - p. 287 95. Chapter 74: Diffuse Large Cell Lymphoma of Lung - p. 291 96. Chapter 75: Intravascular Large B-Cell Lymphoma - p. 299 97. Chapter 76: Hodgkin Lymphoma of Lung - p. 301 98. Chapter 77: Plasmacytoma - p. 305 99. Chapter 78: Lymphomatoid Granulomatosis - p. 307 100. OTHER NEOPLASMS - p. 313 101. Chapter 79: Primary Pulmonary Melanoma - p. 313 102. Chapter 80: Ganglioneuroblastoma - p. 317 103. SECTION 4: NEOPLASMS, METASTATIC - p. 321 104. Chapter 81: Benign Metastasizing Leiomyoma - p. 321 105. Chapter 82: Metastatic Carcinoma - p. 327 106. Chapter 83: Metastatic Sarcoma - p. 339 107. Chapter 84: Metastatic Malignant Melanoma - p. 349 108. SECTION 5: NONNEOPLASTIC AND SYSTEMIC CONDITIONS - p. 357 109. Chapter 85: Diffuse Alveolar Damage - p. 357 110. Chapter 86: Acute Fibrinous and Organizing Pneumonia - p. 363 111. Chapter 87: Organizing Pneumonia - p. 365 112. Chapter 88: Eosinophilic Pneumonia - p. 369 113. Chapter 89: Respiratory Bronchiolitis Interstitial Lung Disease - p. 373 114. Chapter 90: Desquamative Interstitial Pneumonia - p. 375 115. Chapter 91: Other Smoking-Related Changes - p. 379 116. Chapter 92: Usual Interstitial Pneumonia - p. 381 117. Chapter 93: Nonspecific Interstitial Pneumonia - p. 387 118. Chapter 94: Granulomatous-Lymphocytic Interstitial Lung Disease - p. 391 119. Chapter 95: Pleuroparenchymal Fibroelastosis - p. 395 120. Chapter 96: Hypersensitivity Pneumonitis - p. 397 121. Chapter 97: Bronchocentric Granulomatosis - p. 401 122. Chapter 98: Sarcoidosis - p. 403 123. Chapter 99: IgG4-Related Disease - p. 407 124. Chapter 100: Pulmonary Amyloidosis - p. 411 125. Chapter 101: Light Chain Deposition Disease (Pseudoamyloid) - p. 415 126. Chapter 102: Diffuse Alveolar Hemorrhage With and Without Capillaritis - p. 419 127. Chapter 103: Granulomatosis With Polyangiitis (Wegener Granulomatosis) - p. 421 128. Chapter 104: Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) - p. 425 129. Chapter 105: Microscopic Polyangitis - p. 429 130. Chapter 106: Pulmonary Venoocclusive Disease/Pulmonary Capillary Hemangiomatosis - p. 431 131. Chapter 107: Idiopathic Pulmonary Hemosiderosis - p. 435 132. Chapter 108: Hard Metal Pneumoconiosis - p. 437 133. Chapter 109: Asbestos-Related Interstitial Fibrosis/Asbestosis - p. 439 134. Chapter 110: E-Cigarette and Vaping-Associated Lung Injury - p. 443 135. Chapter 111: Alveolar Proteinosis - p. 445 136. Chapter 112: Alveolar Microlithiasis - p. 449 137. Chapter 113: Congenital Pulmonary Airway Malformations - p. 453 138. SECTION 6: INFECTIOUS DISEASES - p. 457 139. PARASITIC - p. 457 140. Chapter 114: Strongyloidiasis - p. 457 141. Chapter 115: Dirofilariasis - p. 463 142. Chapter 116: Schistosomiasis - p. 467 143. Chapter 117: Echinococcosis (Hydatid Cyst) - p. 469 144. Chapter 118: Paragonimiasis - p. 471 145. FUNGAL - p. 473 146. Chapter 119: Cryptococcosis - p. 473 147. Chapter 120: Coccidioidomycosis - p. 477 148. Chapter 121: Pneumocystosis - p. 481 149. Chapter 122: Blastomycosis - p. 485 150. Chapter 123: Histoplasmosis - p. 487 151. Chapter 124: Aspergillosis - p. 491 152. Chapter 125: Mucormycosis (Zygomycosis) - p. 497 153. Chapter 126: Sporotrichosis - p. 499 154. BACTERIAL - p. 501 155. Chapter 127: Tuberculosis - p. 501 156. Chapter 128: Klebsiella Pneumonia - p. 505 157. Chapter 129: Legionnaires' Disease - p. 509 158. Chapter 130: Nocardiosis - p. 511 159. Chapter 131: Actinomycosis - p. 513 160. Chapter 132: Botryomycosis - p. 515 161. Chapter 133: Malakoplakia - p. 517 162. VIRAL - p. 521 163. Chapter 134: Herpes Simplex Virus - p. 521 164. Chapter 135: Cytomegalovirus - p. 525 165. Chapter 136: Adenovirus - p. 527 166. Chapter 137: SARS Pneumonia - p. 529 167. Chapter 138: Measles Pneumonia - p. 535 168. Part II: Pleura - p. 539 169. SECTION 1: BENIGN TUMORS AND REACTIVE CONDITIONS - p. 539 170. Chapter 139: Solitary Fibrous Tumor of Pleura - p. 539 171. Chapter 140: Calcified Fibrous Pseudotumor - p. 549 172. Chapter 141: Pleuropulmonary Endometriosis - p. 553 173. Chapter 142: Mesothelial Hyperplasia - p. 557 174. SECTION 2: NEOPLASMS, MALIGNANT, PRIMARY - p. 559 175. Chapter 143: Overview of Malignant Pleural Neoplasms - p. 559 176. MESOTHELIAL NEOPLASMS - p. 563 177. Chapter 144: Well-Differentiated Papillary Mesothelioma - p. 563 178. Chapter 145: Malignant Mesothelioma - p. 567 179. OTHER MALIGNANT NEOPLASMS - p. 579 180. Chapter 146: Mucoepidermoid Carcinoma of Pleura - p. 579 181. Chapter 147: Angiosarcoma of Pleura - p. 583 182. Chapter 148: Synovial Sarcoma of Pleura - p. 589 183. Chapter 149: Smooth Muscle Tumors of Pleura - p. 595 184. Chapter 150: Desmoplastic Small Round Cell Tumor - p. 599 185. Chapter 151: Primary Effusion Lymphoma - p. 603 186. Part III: Mediastinum - p. 605 187. SECTION 1: BENIGN TUMORS AND REACTIVE CONDITIONS - p. 605 188. Chapter 152: Lymphangioma - p. 605 189. Chapter 153: Hemangioma - p. 611 190. Chapter 154: Paraganglioma - p. 615 191. Chapter 155: Schwannoma - p. 619 192. Chapter 156: Neurofibroma - p. 623 193. Chapter 157: Ectopic Parathyroid Tumor - p. 627 194. Chapter 158: Ectopic Thyroid Tumor - p. 631 195. Chapter 159: Thymolipoma - p. 635 196. Chapter 160: Castleman Disease - p. 639 197. Chapter 161: Simple (Benign) Mediastinal Cysts - p. 645 198. Chapter 162: Acquired Multilocular Thymic Cyst - p. 651 199. Chapter 163: Idiopathic Sclerosing Mediastinitis - p. 659 200. SECTION 2: NEOPLASMS, MALIGNANT, PRIMARY - p. 663 201. EPITHELIAL NEOPLASMS - p. 663 202. Chapter 164: Overview of Malignant Thymic Neoplasms - p. 663 203. Chapter 165: Thymoma - p. 667 204. Chapter 166: Atypical Thymoma (Type B3 Thymoma) - p. 683 205. Chapter 167: Thymic Carcinoma - p. 691 206. Chapter 168: Neuroendocrine Carcinomas of Thymus - p. 701 207. GERM CELL TUMORS - p. 709 208. Chapter 169: Mediastinal Teratoma - p. 709 209. Chapter 170: Mediastinal Seminoma - p. 715 210. Chapter 171: Yolk Sac Tumor - p. 719 211. Chapter 172: Choriocarcinoma - p. 725 212. Chapter 173: Embryonal Carcinoma - p. 729 213. HEMATOPOIETIC MALIGNANCIES - p. 733 214. Chapter 174: Hodgkin Lymphoma of Mediastinum - p. 733 215. Chapter 175: Diffuse Large Cell Lymphoma of Mediastinum - p. 741 216. Chapter 176: Lymphoblastic Lymphoma - p. 755 217. Chapter 177: MALT Lymphoma of Thymus - p. 761 218. MESENCHYMAL NEOPLASMS - p. 765 219. Chapter 178: Liposarcoma - p. 765 220. Chapter 179: Leiomyosarcoma of Mediastinum - p. 773 221. Chapter 180: Synovial Sarcoma of Mediastinum - p. 777 222. Chapter 181: Malignant Peripheral Nerve Sheath Tumor of Mediastinum - p. 789 223. Chapter 182: Solitary Fibrous Tumor of Mediastinum - p. 795 224. Chapter 183: Epithelioid Hemangioendothelioma of Mediastinum - p. 803 225. Chapter 184: Mesenchymal Chondrosarcoma - p. 811 226. Chapter 185: Chordoma - p. 815 227. Chapter 186: Alveolar Soft Part Sarcoma - p. 821 228. Chapter 187: Rhabdomyosarcoma - p. 825 229. SYMPATHETIC NERVOUS SYSTEM TUMORS - p. 829 230. Chapter 188: Ganglioneuroma - p. 829 231. Chapter 189: Neuroblastoma/Ganglioneuroblastoma - p. 833 232. Chapter 190: Ependymoma - p. 839 233. INDEX - p. 843
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of thoracic pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Thoracic is a one-stop reference for accurate, rapid, and complete pathology reports—ideal as a day-to-day reference or as a reliable training resource.
Provides a clear framework for a better understanding of the clinical and histopathologic appearances of pulmonary, pleural, and mediastinal entities
Features an updated chapter on severe acute respiratory syndrome (SARS) pneumonia with current knowledge, statistics, and pathophysiology on COVID-19, including new images that encompass the radiology, gross pathology, and histopathology of the disease
Includes updated criteria, terminology, and classifications for a wide range of tumors from the 2021 World Health Organization Classification of Tumors of the Lung, Pleura, Thymus and Heart, reflecting changes to currently used terminologies for adenocarcinoma, squamous cell carcinoma, neuroendocrine tumors, mesothelioma, soft tissue tumors, benign tumors, and more
Covers the recent explosion of molecular genetic information, including new Molecular Pathology sections with new information on the genetic underpinnings of diseases
Specifies genetic mutation types associated with each tumor and covers numerous types of molecular tests, including next-generation sequencing studies and how the specific genetic alterations are used to differentiate disease and aid in diagnosis
Features over 3,900 high-quality images, including histologic images, gross pathology images, radiologic images, and full-color illustrations as well as more than 750 additional online-only images to help practicing and in-training pathologists reach a confident diagnosis
Contains multiple recent consensus clinical practice guidelines for thoracic disease diagnosis, including those for molecular genetic testing and predictive biomarker testing from the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology
Employs consistently templated chapters, bulleted content, key facts, and annotated images for quick, expert reference at the point of care
1. Cover image - p. Cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedications - p. iii 6. Preface - p. v 7. Acknowledgments - p. vii 8. Sections - p. ix 9. Part I: Lung - p. xi 10. SECTION 1: NEOPLASMS, BENIGN - p. xi 11. List of Tables - p. xi 12. Chapter 1: Congenital Peribronchial Myofibroblastic Tumor - p. xi 13. Chapter 2: Fetal Lung Interstitial Tumor - p. 5 14. Chapter 3: Mucous Gland Adenoma - p. 7 15. Chapter 4: Ciliated Muconodular Papillary Tumor/Bronchiolar Adenoma - p. 11 16. Chapter 5: Alveolar Adenoma - p. 13 17. Chapter 6: Sclerosing Pneumocytoma - p. 17 18. Chapter 7: Cartilaginous Hamartoma - p. 23 19. Chapter 8: Endobronchial Lipoma - p. 27 20. Chapter 9: Pulmonary Adenofibroma/Adenomyoma - p. 29 21. Chapter 10: Glomus Tumor - p. 33 22. Chapter 11: Pulmonary Paraganglioma - p. 35 23. Chapter 12: Pulmonary Meningioma - p. 39 24. Chapter 13: Minute Pulmonary Meningothelial-Like Nodule - p. 43 25. Chapter 14: Granular Cell Tumor - p. 47 26. Chapter 15: Langerhans Cell Histiocytosis - p. 49 27. Chapter 16: Erdheim-Chester Disease - p. 53 28. Chapter 17: Pulmonary PEComa (Clear Cell Sugar Tumor) - p. 57 29. Chapter 18: Lymphangioleiomyomatosis - p. 61 30. SECTION 2: OTHER RARE TUMORS AND BENIGN PSEUDOTUMORAL CONDITIONS - p. 65 31. Chapter 19: Inflammatory Myofibroblastic Tumor - p. 65 32. Chapter 20: Intrapulmonary Thymoma - p. 71 33. Chapter 21: Juvenile Xanthogranuloma - p. 75 34. Chapter 22: Hyalinizing Granuloma - p. 79 35. Chapter 23: Metastatic/Dendriform Calcification - p. 83 36. Chapter 24: Lipoid Pneumonia - p. 87 37. Chapter 25: Placental Transmogrification - p. 89 38. Chapter 26: Rosai-Dorfman Disease - p. 93 39. Chapter 27: Epithelioid Hemangioma - p. 97 40. SECTION 3: NEOPLASMS, MALIGNANT, PRIMARY - p. 99 41. ADENOCARCINOMA - p. 99 42. Chapter 28: Overview of Malignant Epithelial Neoplasms of Lung - p. 99 43. Chapter 29: Conventional Adenocarcinoma - p. 105 44. Chapter 30: Lepidic-Predominant Adenocarcinoma - p. 117 45. ADENOCARCINOMA VARIANTS - p. 119 46. Chapter 31: Invasive Mucinous Adenocarcinoma - p. 119 47. Chapter 32: Colloid Adenocarcinoma - p. 123 48. Chapter 33: Fetal Adenocarcinoma - p. 127 49. Chapter 34: Enteric-Type Adenocarcinoma - p. 131 50. Chapter 35: Other Adenocarcinoma Variants - p. 133 51. Chapter 36: Adenosquamous Carcinoma - p. 137 52. SQUAMOUS CELL CARCINOMA - p. 141 53. Chapter 37: Conventional Squamous Cell Carcinoma - p. 141 54. Chapter 38: Basaloid/Small Cell Variant of Squamous Cell Carcinoma - p. 147 55. Chapter 39: Lymphoepithelioma-Like Carcinoma - p. 151 56. NEUROENDOCRINE CARCINOMA AND PRECURSOR LESIONS - p. 155 57. Chapter 40: Overview of Neuroendocrine Neoplasms - p. 155 58. Chapter 41: Pulmonary Tumorlet and Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia - p. 159 59. Chapter 42: Low-Grade Neuroendocrine Carcinoma (Typical Carcinoid Tumor) - p. 161 60. Chapter 43: Intermediate-Grade Neuroendocrine Carcinoma (Atypical Carcinoid Tumor) - p. 167 61. Chapter 44: High-Grade Neuroendocrine Carcinoma, Small Cell Type - p. 171 62. Chapter 45: High-Grade Neuroendocrine Carcinoma, Large Cell Type - p. 175 63. POORLY DIFFERENTIATED NON-SMALL CELL CARCINOMAS - p. 179 64. Chapter 46: Overview of Poorly Differentiated Non-Small Cell Carcinomas - p. 179 65. Chapter 47: Large Cell Carcinoma - p. 181 66. Chapter 48: Pleomorphic Carcinoma - p. 183 67. Chapter 49: Spindle Cell Carcinoma - p. 187 68. Chapter 50: Carcinosarcoma - p. 191 69. Chapter 51: Pulmonary Blastoma - p. 195 70. Chapter 52: SMARCA4-Deficient Undifferentiated Tumors - p. 199 71. Chapter 53: NUT Carcinoma - p. 203 72. SALIVARY GLAND-TYPE TUMORS - p. 205 73. Chapter 54: Adenoid Cystic Carcinoma - p. 205 74. Chapter 55: Mucoepidermoid Carcinoma of Lung - p. 211 75. Chapter 56: Epithelial-Myoepithelial Carcinoma - p. 217 76. Chapter 57: Acinic Cell Carcinoma - p. 221 77. Chapter 58: Mixed Tumor (Pleomorphic Adenoma) - p. 225 78. Chapter 59: Myoepithelial Carcinoma - p. 229 79. MESENCHYMAL NEOPLASMS - p. 233 80. Chapter 60: Pleuropulmonary Blastoma - p. 233 81. Chapter 61: Primary Pulmonary Myxoid Sarcoma - p. 237 82. Chapter 62: Intrapulmonary Solitary Fibrous Tumor - p. 239 83. Chapter 63: Leiomyosarcoma of Lung - p. 243 84. Chapter 64: Intrapulmonary Synovial Sarcoma - p. 247 85. Chapter 65: Malignant Peripheral Nerve Sheath Tumor of Lung - p. 253 86. Chapter 66: Osteosarcoma - p. 257 87. Chapter 67: Chondrosarcoma - p. 261 88. Chapter 68: Epithelioid Hemangioendothelioma of Lung - p. 265 89. Chapter 69: Angiosarcoma of Lung - p. 273 90. Chapter 70: Kaposi Sarcoma - p. 277 91. Chapter 71: Intimal Sarcoma - p. 281 92. LYMPHOPROLIFERATIVE DISORDERS - p. 285 93. Chapter 72: Benign Pulmonary Lymphoid Lesions - p. 285 94. Chapter 73: Pulmonary BALT Lymphoma - p. 287 95. Chapter 74: Diffuse Large Cell Lymphoma of Lung - p. 291 96. Chapter 75: Intravascular Large B-Cell Lymphoma - p. 299 97. Chapter 76: Hodgkin Lymphoma of Lung - p. 301 98. Chapter 77: Plasmacytoma - p. 305 99. Chapter 78: Lymphomatoid Granulomatosis - p. 307 100. OTHER NEOPLASMS - p. 313 101. Chapter 79: Primary Pulmonary Melanoma - p. 313 102. Chapter 80: Ganglioneuroblastoma - p. 317 103. SECTION 4: NEOPLASMS, METASTATIC - p. 321 104. Chapter 81: Benign Metastasizing Leiomyoma - p. 321 105. Chapter 82: Metastatic Carcinoma - p. 327 106. Chapter 83: Metastatic Sarcoma - p. 339 107. Chapter 84: Metastatic Malignant Melanoma - p. 349 108. SECTION 5: NONNEOPLASTIC AND SYSTEMIC CONDITIONS - p. 357 109. Chapter 85: Diffuse Alveolar Damage - p. 357 110. Chapter 86: Acute Fibrinous and Organizing Pneumonia - p. 363 111. Chapter 87: Organizing Pneumonia - p. 365 112. Chapter 88: Eosinophilic Pneumonia - p. 369 113. Chapter 89: Respiratory Bronchiolitis Interstitial Lung Disease - p. 373 114. Chapter 90: Desquamative Interstitial Pneumonia - p. 375 115. Chapter 91: Other Smoking-Related Changes - p. 379 116. Chapter 92: Usual Interstitial Pneumonia - p. 381 117. Chapter 93: Nonspecific Interstitial Pneumonia - p. 387 118. Chapter 94: Granulomatous-Lymphocytic Interstitial Lung Disease - p. 391 119. Chapter 95: Pleuroparenchymal Fibroelastosis - p. 395 120. Chapter 96: Hypersensitivity Pneumonitis - p. 397 121. Chapter 97: Bronchocentric Granulomatosis - p. 401 122. Chapter 98: Sarcoidosis - p. 403 123. Chapter 99: IgG4-Related Disease - p. 407 124. Chapter 100: Pulmonary Amyloidosis - p. 411 125. Chapter 101: Light Chain Deposition Disease (Pseudoamyloid) - p. 415 126. Chapter 102: Diffuse Alveolar Hemorrhage With and Without Capillaritis - p. 419 127. Chapter 103: Granulomatosis With Polyangiitis (Wegener Granulomatosis) - p. 421 128. Chapter 104: Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) - p. 425 129. Chapter 105: Microscopic Polyangitis - p. 429 130. Chapter 106: Pulmonary Venoocclusive Disease/Pulmonary Capillary Hemangiomatosis - p. 431 131. Chapter 107: Idiopathic Pulmonary Hemosiderosis - p. 435 132. Chapter 108: Hard Metal Pneumoconiosis - p. 437 133. Chapter 109: Asbestos-Related Interstitial Fibrosis/Asbestosis - p. 439 134. Chapter 110: E-Cigarette and Vaping-Associated Lung Injury - p. 443 135. Chapter 111: Alveolar Proteinosis - p. 445 136. Chapter 112: Alveolar Microlithiasis - p. 449 137. Chapter 113: Congenital Pulmonary Airway Malformations - p. 453 138. SECTION 6: INFECTIOUS DISEASES - p. 457 139. PARASITIC - p. 457 140. Chapter 114: Strongyloidiasis - p. 457 141. Chapter 115: Dirofilariasis - p. 463 142. Chapter 116: Schistosomiasis - p. 467 143. Chapter 117: Echinococcosis (Hydatid Cyst) - p. 469 144. Chapter 118: Paragonimiasis - p. 471 145. FUNGAL - p. 473 146. Chapter 119: Cryptococcosis - p. 473 147. Chapter 120: Coccidioidomycosis - p. 477 148. Chapter 121: Pneumocystosis - p. 481 149. Chapter 122: Blastomycosis - p. 485 150. Chapter 123: Histoplasmosis - p. 487 151. Chapter 124: Aspergillosis - p. 491 152. Chapter 125: Mucormycosis (Zygomycosis) - p. 497 153. Chapter 126: Sporotrichosis - p. 499 154. BACTERIAL - p. 501 155. Chapter 127: Tuberculosis - p. 501 156. Chapter 128: Klebsiella Pneumonia - p. 505 157. Chapter 129: Legionnaires' Disease - p. 509 158. Chapter 130: Nocardiosis - p. 511 159. Chapter 131: Actinomycosis - p. 513 160. Chapter 132: Botryomycosis - p. 515 161. Chapter 133: Malakoplakia - p. 517 162. VIRAL - p. 521 163. Chapter 134: Herpes Simplex Virus - p. 521 164. Chapter 135: Cytomegalovirus - p. 525 165. Chapter 136: Adenovirus - p. 527 166. Chapter 137: SARS Pneumonia - p. 529 167. Chapter 138: Measles Pneumonia - p. 535 168. Part II: Pleura - p. 539 169. SECTION 1: BENIGN TUMORS AND REACTIVE CONDITIONS - p. 539 170. Chapter 139: Solitary Fibrous Tumor of Pleura - p. 539 171. Chapter 140: Calcified Fibrous Pseudotumor - p. 549 172. Chapter 141: Pleuropulmonary Endometriosis - p. 553 173. Chapter 142: Mesothelial Hyperplasia - p. 557 174. SECTION 2: NEOPLASMS, MALIGNANT, PRIMARY - p. 559 175. Chapter 143: Overview of Malignant Pleural Neoplasms - p. 559 176. MESOTHELIAL NEOPLASMS - p. 563 177. Chapter 144: Well-Differentiated Papillary Mesothelioma - p. 563 178. Chapter 145: Malignant Mesothelioma - p. 567 179. OTHER MALIGNANT NEOPLASMS - p. 579 180. Chapter 146: Mucoepidermoid Carcinoma of Pleura - p. 579 181. Chapter 147: Angiosarcoma of Pleura - p. 583 182. Chapter 148: Synovial Sarcoma of Pleura - p. 589 183. Chapter 149: Smooth Muscle Tumors of Pleura - p. 595 184. Chapter 150: Desmoplastic Small Round Cell Tumor - p. 599 185. Chapter 151: Primary Effusion Lymphoma - p. 603 186. Part III: Mediastinum - p. 605 187. SECTION 1: BENIGN TUMORS AND REACTIVE CONDITIONS - p. 605 188. Chapter 152: Lymphangioma - p. 605 189. Chapter 153: Hemangioma - p. 611 190. Chapter 154: Paraganglioma - p. 615 191. Chapter 155: Schwannoma - p. 619 192. Chapter 156: Neurofibroma - p. 623 193. Chapter 157: Ectopic Parathyroid Tumor - p. 627 194. Chapter 158: Ectopic Thyroid Tumor - p. 631 195. Chapter 159: Thymolipoma - p. 635 196. Chapter 160: Castleman Disease - p. 639 197. Chapter 161: Simple (Benign) Mediastinal Cysts - p. 645 198. Chapter 162: Acquired Multilocular Thymic Cyst - p. 651 199. Chapter 163: Idiopathic Sclerosing Mediastinitis - p. 659 200. SECTION 2: NEOPLASMS, MALIGNANT, PRIMARY - p. 663 201. EPITHELIAL NEOPLASMS - p. 663 202. Chapter 164: Overview of Malignant Thymic Neoplasms - p. 663 203. Chapter 165: Thymoma - p. 667 204. Chapter 166: Atypical Thymoma (Type B3 Thymoma) - p. 683 205. Chapter 167: Thymic Carcinoma - p. 691 206. Chapter 168: Neuroendocrine Carcinomas of Thymus - p. 701 207. GERM CELL TUMORS - p. 709 208. Chapter 169: Mediastinal Teratoma - p. 709 209. Chapter 170: Mediastinal Seminoma - p. 715 210. Chapter 171: Yolk Sac Tumor - p. 719 211. Chapter 172: Choriocarcinoma - p. 725 212. Chapter 173: Embryonal Carcinoma - p. 729 213. HEMATOPOIETIC MALIGNANCIES - p. 733 214. Chapter 174: Hodgkin Lymphoma of Mediastinum - p. 733 215. Chapter 175: Diffuse Large Cell Lymphoma of Mediastinum - p. 741 216. Chapter 176: Lymphoblastic Lymphoma - p. 755 217. Chapter 177: MALT Lymphoma of Thymus - p. 761 218. MESENCHYMAL NEOPLASMS - p. 765 219. Chapter 178: Liposarcoma - p. 765 220. Chapter 179: Leiomyosarcoma of Mediastinum - p. 773 221. Chapter 180: Synovial Sarcoma of Mediastinum - p. 777 222. Chapter 181: Malignant Peripheral Nerve Sheath Tumor of Mediastinum - p. 789 223. Chapter 182: Solitary Fibrous Tumor of Mediastinum - p. 795 224. Chapter 183: Epithelioid Hemangioendothelioma of Mediastinum - p. 803 225. Chapter 184: Mesenchymal Chondrosarcoma - p. 811 226. Chapter 185: Chordoma - p. 815 227. Chapter 186: Alveolar Soft Part Sarcoma - p. 821 228. Chapter 187: Rhabdomyosarcoma - p. 825 229. SYMPATHETIC NERVOUS SYSTEM TUMORS - p. 829 230. Chapter 188: Ganglioneuroma - p. 829 231. Chapter 189: Neuroblastoma/Ganglioneuroblastoma - p. 833 232. Chapter 190: Ependymoma - p. 839 233. INDEX - p. 843
