The second edition of Dorfman and Czerniak's Bone Tumors brings together the latest data available on bone tumor pathology, making it the most comprehensive and encyclopedic reference on the epidemiology, clinical, pathologic, and molecular aspects of bone tumors. Now offered in full color and featuring updated imaging throughout, this one-of-a-kind resource provides a highly visual review of every disorder — from the common to the rare.
1. Introduction - p. 1 2. Morphology of Normal Bone - p. 3 3. Processing of Bone Specimens - p. 12 4. Staging, Grading, and Reporting of Bone Tumors - p. 17 5. General Epidemiology of Bone Tumors - p. 24 6. Special Techniques - p. 28 7. Special Stains - p. 30 8. Electron Microscopy - p. 32 9. Cytometry and Histomorphometry - p. 33 10. Immunohistochemistry - p. 37 11. Cytogenetics - p. 47 12. References - p. 49 13. Chapter 2 Clinical Considerations and Imaging of Bone Tumors - p. 57 14. Chapter 3 Molecular Biology of Bone Tumors - p. 96 15. Molecular Techniques - p. 96 16. Molecular Biology of Bone Formation - p. 100 17. Mechanisms of Malignant Transformation - p. 106 18. Cell-Cycle and Mitotic Regulation - p. 125 19. Molecular Concepts of Bone Neoplasia - p. 131 20. References - p. 135 21. Chapter 4 Benign Osteoblastic Tumors - p. 144 22. Chapter 5 Osteosarcoma - p. 200 23. Intramedullary Osteosarcoma - p. 200 24. Osteosarcoma Associated with Specific Clinical Syndromes - p. 304 25. Secondary Osteosarcoma - p. 304 26. Surface Osteosarcoma - p. 309 27. Intracortical Osteosarcoma - p. 342 28. Extraskeletal Osteosarcoma - p. 345 29. References - p. 347 30. Chapter 6 Benign Cartilage Lesions - p. 356 31. Enchondroma - p. 356 32. Periosteal Chondroma - p. 377 33. Enchondromatosis - p. 386 34. Chondroblastoma - p. 400 35. Chondromyxoid Fibroma - p. 425 36. Osteochondroma - p. 438 37. References - p. 466 38. Chapter 7 Malignant Cartilage Tumors - p. 474 39. Intramedullary Chondrosarcoma - p. 474 40. Juxtacortical Chondrosarcoma - p. 559 41. Secondary Chondrosarcomas - p. 560 42. References - p. 565 43. Chapter 8 Fibrous Dysplasia and Related Lesions - p. 570 44. Chapter 9 Fibrous and Fibrohistiocytic Lesions - p. 617 45. Chapter 10 Giant Cell Lesions - p. 692 46. Chapter 11 Ewing's Sarcoma and Related Tumors - p. 760 47. Chapter 12 Hematopoietic Tumors - p. 817 48. Classification of Hematopoietic Tumors - p. 817 49. Plasma Cell Myeloma and Plasma Cell Neoplasms - p. 817 50. Non-Hodgkin's Lymphoma - p. 842 51. Classical Hodgkin's Lymphoma - p. 855 52. Histiocytic and Dendritic Cell Proliferations - p. 862 53. Myeloid Sarcoma - p. 885 54. Mastocytosis - p. 890 55. References - p. 896 56. Chapter 13 Vascular Lesions - p. 903 57. Chapter 14 Neurogenous Tumors and Neurofibromatosis Affecting Bone - p. 990 58. Chapter 15 Cystic Lesions - p. 1055 59. Chapter 16 Miscellaneous Mesenchymal Tumors - p. 1100 60. Chapter 17 Adamantinoma of Long Bone - p. 1142 61. Chapter 18 Chordoma and Related Lesions - p. 1174 62. Chapter 19 Metastatic Tumors in Bone - p. 1217 63. Chapter 20 Synovial Lesions - p. 1259 64. Chapter 21 Sclerosing Bone Lesions - p. 1317 65. Chapter 22 Tumor-Induced Osteomalacia and Rickets - p. 1346 66. Chapter 23 Reactive and Metabolic Conditions Simulating Neoplasms of Bone - p. 1357 67. Chapter 24 Precancerous Conditions - p. 1437 68. Index - p. 1485
The second edition of Dorfman and Czerniak's Bone Tumors brings together the latest data available on bone tumor pathology, making it the most comprehensive and encyclopedic reference on the epidemiology, clinical, pathologic, and molecular aspects of bone tumors. Now offered in full color and featuring updated imaging throughout, this one-of-a-kind resource provides a highly visual review of every disorder — from the common to the rare.
1. Introduction - p. 1 2. Morphology of Normal Bone - p. 3 3. Processing of Bone Specimens - p. 12 4. Staging, Grading, and Reporting of Bone Tumors - p. 17 5. General Epidemiology of Bone Tumors - p. 24 6. Special Techniques - p. 28 7. Special Stains - p. 30 8. Electron Microscopy - p. 32 9. Cytometry and Histomorphometry - p. 33 10. Immunohistochemistry - p. 37 11. Cytogenetics - p. 47 12. References - p. 49 13. Chapter 2 Clinical Considerations and Imaging of Bone Tumors - p. 57 14. Chapter 3 Molecular Biology of Bone Tumors - p. 96 15. Molecular Techniques - p. 96 16. Molecular Biology of Bone Formation - p. 100 17. Mechanisms of Malignant Transformation - p. 106 18. Cell-Cycle and Mitotic Regulation - p. 125 19. Molecular Concepts of Bone Neoplasia - p. 131 20. References - p. 135 21. Chapter 4 Benign Osteoblastic Tumors - p. 144 22. Chapter 5 Osteosarcoma - p. 200 23. Intramedullary Osteosarcoma - p. 200 24. Osteosarcoma Associated with Specific Clinical Syndromes - p. 304 25. Secondary Osteosarcoma - p. 304 26. Surface Osteosarcoma - p. 309 27. Intracortical Osteosarcoma - p. 342 28. Extraskeletal Osteosarcoma - p. 345 29. References - p. 347 30. Chapter 6 Benign Cartilage Lesions - p. 356 31. Enchondroma - p. 356 32. Periosteal Chondroma - p. 377 33. Enchondromatosis - p. 386 34. Chondroblastoma - p. 400 35. Chondromyxoid Fibroma - p. 425 36. Osteochondroma - p. 438 37. References - p. 466 38. Chapter 7 Malignant Cartilage Tumors - p. 474 39. Intramedullary Chondrosarcoma - p. 474 40. Juxtacortical Chondrosarcoma - p. 559 41. Secondary Chondrosarcomas - p. 560 42. References - p. 565 43. Chapter 8 Fibrous Dysplasia and Related Lesions - p. 570 44. Chapter 9 Fibrous and Fibrohistiocytic Lesions - p. 617 45. Chapter 10 Giant Cell Lesions - p. 692 46. Chapter 11 Ewing's Sarcoma and Related Tumors - p. 760 47. Chapter 12 Hematopoietic Tumors - p. 817 48. Classification of Hematopoietic Tumors - p. 817 49. Plasma Cell Myeloma and Plasma Cell Neoplasms - p. 817 50. Non-Hodgkin's Lymphoma - p. 842 51. Classical Hodgkin's Lymphoma - p. 855 52. Histiocytic and Dendritic Cell Proliferations - p. 862 53. Myeloid Sarcoma - p. 885 54. Mastocytosis - p. 890 55. References - p. 896 56. Chapter 13 Vascular Lesions - p. 903 57. Chapter 14 Neurogenous Tumors and Neurofibromatosis Affecting Bone - p. 990 58. Chapter 15 Cystic Lesions - p. 1055 59. Chapter 16 Miscellaneous Mesenchymal Tumors - p. 1100 60. Chapter 17 Adamantinoma of Long Bone - p. 1142 61. Chapter 18 Chordoma and Related Lesions - p. 1174 62. Chapter 19 Metastatic Tumors in Bone - p. 1217 63. Chapter 20 Synovial Lesions - p. 1259 64. Chapter 21 Sclerosing Bone Lesions - p. 1317 65. Chapter 22 Tumor-Induced Osteomalacia and Rickets - p. 1346 66. Chapter 23 Reactive and Metabolic Conditions Simulating Neoplasms of Bone - p. 1357 67. Chapter 24 Precancerous Conditions - p. 1437 68. Index - p. 1485
