Elemene Antitumor Drugs: Molecular Compatibility Theory and its Applications in New Drug Development and Clinical Practice introduces natural anti-tumor drug elemene and systematic basic and clinical research. Basic principles of the compatibility theory of traditional Chinese medicine and the research and development process of the natural anti-tumor drug elemene under the guidance of this principle are introduced. In addition, the traditional extraction and separation of elemene and the new biosynthesis technology developed by the author's team are described. Then, the systematic anti-tumor mechanism research of elemene are introduced, including unique multi-target and comprehensive anti-tumor mechanisms and detailed mechanisms for treating specific tumors.
Under the guidance of compatibility theory, clinical research on the combined application of elemene and different chemotherapeutic drugs has been further carried out, achieving positive results in clinical practice. Finally, the book also introduces the research and exploration of new drug delivery systems of elemene, as well as the structural modification and drug discovery progress taking elemene structure as the lead compound.
1. Elemene Antitumor Drugs - p. i 2. Cover - p. i 3. Title Page - p. iii 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Forward I - p. iv 7. Forward II - p. x 8. Chapter 1 Molecular Compatibility Theory and Its Applications in Tumor Treatment - p. 3 9. Chapter 2 Research and Development of The Antitumor Drug Elemene Liposome - p. 33 10. Chapter 3 Traditional Extraction and Separation, Manufacturing Process, and Quality Standards of Elemene - p. 47 11. Chapter 4 Advances in The Biosynthesis of β-elemene - p. 61 12. Chapter 5 An Overview of The Anticancer Mechanism of Elemene - p. 93 13. Chapter 6 Antitumor Mechanisms of Elemene in Specific Cancers - p. 117 14. Chapter 7 Clinical Applications of Elemene - p. 151 15. Chapter 8 Clinical Research on Drug Combination Based on Elemene - p. 215 16. Chapter 9 Developing a Novel Drug Delivery System for Elemene to Synergize Therapeutic Strategies - p. 245 17. Chapter 10 Structural Optimization and Modification Based on β-elemene - p. 259 18. Index - p. 281
Elemene Antitumor Drugs: Molecular Compatibility Theory and its Applications in New Drug Development and Clinical Practice introduces natural anti-tumor drug elemene and systematic basic and clinical research. Basic principles of the compatibility theory of traditional Chinese medicine and the research and development process of the natural anti-tumor drug elemene under the guidance of this principle are introduced. In addition, the traditional extraction and separation of elemene and the new biosynthesis technology developed by the author's team are described. Then, the systematic anti-tumor mechanism research of elemene are introduced, including unique multi-target and comprehensive anti-tumor mechanisms and detailed mechanisms for treating specific tumors.
Under the guidance of compatibility theory, clinical research on the combined application of elemene and different chemotherapeutic drugs has been further carried out, achieving positive results in clinical practice. Finally, the book also introduces the research and exploration of new drug delivery systems of elemene, as well as the structural modification and drug discovery progress taking elemene structure as the lead compound.
1. Elemene Antitumor Drugs - p. i 2. Cover - p. i 3. Title Page - p. iii 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Forward I - p. iv 7. Forward II - p. x 8. Chapter 1 Molecular Compatibility Theory and Its Applications in Tumor Treatment - p. 3 9. Chapter 2 Research and Development of The Antitumor Drug Elemene Liposome - p. 33 10. Chapter 3 Traditional Extraction and Separation, Manufacturing Process, and Quality Standards of Elemene - p. 47 11. Chapter 4 Advances in The Biosynthesis of β-elemene - p. 61 12. Chapter 5 An Overview of The Anticancer Mechanism of Elemene - p. 93 13. Chapter 6 Antitumor Mechanisms of Elemene in Specific Cancers - p. 117 14. Chapter 7 Clinical Applications of Elemene - p. 151 15. Chapter 8 Clinical Research on Drug Combination Based on Elemene - p. 215 16. Chapter 9 Developing a Novel Drug Delivery System for Elemene to Synergize Therapeutic Strategies - p. 245 17. Chapter 10 Structural Optimization and Modification Based on β-elemene - p. 259 18. Index - p. 281
