Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes, Second Edition offers new discoveries in clinical settings, cellular, molecular, genetic, and epigenetic mechanisms which have led to novel understanding of the key role of endothelium in both cardiovascular and non-cardiovascular diseases. The innovations it presents have implications for both pathophysiological concepts and clinical decisions. Among other topics, cardiovascular and pulmonary medicine, immunity and inflammation, genetics and epigenetics, heart failure, renal disease, familial hypercholesterolemia, diabetes, and hypertension are discussed at length.
With 20 new chapters covering everything from endothelium transition to connective tissue disorders, this second edition is sure to be indispensable to anyone wishing to learn the importance of endothelium to every facet of health.
1. Introduction - p. 355 2. Mediterranean Diet - p. 356 3. Dietary Approaches to Stop Hypertension—Dash Diet - p. 359 4. Plant-Based Diet - p. 361 5. Foods and Nutrients Beyond Health Dietary Patterns - p. 363 6. Conclusions - p. 375 7. Chapter 28. Endothelium and Microbiota as Regulators of Metabolic Processes - p. 385 8. Chapter 29. Effects of Red Wine and Polyphenols on Endothelial Function and Clinical Events - p. 399 9. Section VI. Kidney and Hypertension - p. S6 10. Chapter 30. Kidney and the Endothelium - p. 429 11. Chapter 31. Advancements in Understanding the Interplay Between Endothelial Dysfunction and Arterial Hypertension - p. 437 12. Section VII. Atherosclerosis and Coronary Disease - p. S7 13. Chapter 32. Endothelial Alterations in Chronic Coronary Disease - p. 449 14. Chapter 33. Molecular Mechanisms of the Arterial Wall in Acute Coronary Syndromes - p. 471 15. Chapter 34. Integrating Multiomic Approaches to Uncover Candidate Gene Networks for Endothelial Dysfunction in Response to Cardiovascular Risk Factors - p. 481 16. Chapter 35. Endothelium: Coordinator of Acute and Chronic Inflammation - p. 487 17. Chapter 36. Endothelium in Atherosclerosis: Plaque Formation and Its Complications - p. 495 18. Chapter 37. Endothelial Function and Cardiovascular Risk Factors - p. 511 19. Chapter 38. Colchicine for the Prevention of Cardiovascular Disease - p. 527 20. Section VIII. Heart Failure and Minoca - p. S8 21. Chapter 39. Endothelial Dysfunction and Microcirculation in Women with Angina and Normal Coronaries - p. 541 22. Chapter 40. Endothelial Alterations in Heart Failure: Mechanisms, Molecular Bases, and Therapeutic Implications - p. 551 23. Chapter 41. Endothelial Function in Heart Failure With Preserved Ejection Fraction - p. 561 24. Chapter 42. Endothelium in Cardiomyopathies - p. 569 25. Section IX. Percutaneous Interventions and Transplant - p. S9 26. Chapter 43. Postpercutaneous Interventions: Endothelial Repair - p. 585 27. Chapter 44. Stents and the Endothelium - p. 591 28. Chapter 45. Vascular Disease of the Transplanted Heart: Physiopathology and Therapeutic Options - p. 597 29. Section X. Endothelium and Systemic Diseases - p. S10 30. Chapter 46. Sleep Disorders and Endothelial Dysfunction - p. 615 31. Chapter 47. Smoking and the Endothelium - p. 625 32. Chapter 48. Effects of Radiation on Vascular Endothelium - p. 653 33. Chapter 49. Erectile Dysfunction and the Endothelium - p. 665 34. Chapter 50. Cardiovascular Actions and Therapeutic Implications of Endothelium-Derived Catecholamines - p. 675 35. Chapter 51. Obesity, Endothelium, and Metabolic Syndrome - p. 689 36. Chapter 52. Endothelium in Diabetes - p. 699 37. Chapter 53. Endothelial Mechanisms in Preeclampsia - p. 711 38. Chapter 54. Endothelium and Nitric Oxide: Interactions in Cancer Evolution - p. 721 39. Chapter 55. Corneal Endothelium Cell Dysfunction - p. 735 40. Chapter 56. Connective Tissue and Endothelium - p. 743 41. Chapter 57. Endothelial Alterations in Pulmonary Hypertension - p. 751 42. Chapter 58. Physical Exercise and Endothelium - p. 767 43. Section XI. Overview - p. S11 44. Chapter 59. The Translational Concept in Endothelium—From Research to Clinical Practice - p. 781 45. Index - p. 787
Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes, Second Edition offers new discoveries in clinical settings, cellular, molecular, genetic, and epigenetic mechanisms which have led to novel understanding of the key role of endothelium in both cardiovascular and non-cardiovascular diseases. The innovations it presents have implications for both pathophysiological concepts and clinical decisions. Among other topics, cardiovascular and pulmonary medicine, immunity and inflammation, genetics and epigenetics, heart failure, renal disease, familial hypercholesterolemia, diabetes, and hypertension are discussed at length.
With 20 new chapters covering everything from endothelium transition to connective tissue disorders, this second edition is sure to be indispensable to anyone wishing to learn the importance of endothelium to every facet of health.
1. Introduction - p. 355 2. Mediterranean Diet - p. 356 3. Dietary Approaches to Stop Hypertension—Dash Diet - p. 359 4. Plant-Based Diet - p. 361 5. Foods and Nutrients Beyond Health Dietary Patterns - p. 363 6. Conclusions - p. 375 7. Chapter 28. Endothelium and Microbiota as Regulators of Metabolic Processes - p. 385 8. Chapter 29. Effects of Red Wine and Polyphenols on Endothelial Function and Clinical Events - p. 399 9. Section VI. Kidney and Hypertension - p. S6 10. Chapter 30. Kidney and the Endothelium - p. 429 11. Chapter 31. Advancements in Understanding the Interplay Between Endothelial Dysfunction and Arterial Hypertension - p. 437 12. Section VII. Atherosclerosis and Coronary Disease - p. S7 13. Chapter 32. Endothelial Alterations in Chronic Coronary Disease - p. 449 14. Chapter 33. Molecular Mechanisms of the Arterial Wall in Acute Coronary Syndromes - p. 471 15. Chapter 34. Integrating Multiomic Approaches to Uncover Candidate Gene Networks for Endothelial Dysfunction in Response to Cardiovascular Risk Factors - p. 481 16. Chapter 35. Endothelium: Coordinator of Acute and Chronic Inflammation - p. 487 17. Chapter 36. Endothelium in Atherosclerosis: Plaque Formation and Its Complications - p. 495 18. Chapter 37. Endothelial Function and Cardiovascular Risk Factors - p. 511 19. Chapter 38. Colchicine for the Prevention of Cardiovascular Disease - p. 527 20. Section VIII. Heart Failure and Minoca - p. S8 21. Chapter 39. Endothelial Dysfunction and Microcirculation in Women with Angina and Normal Coronaries - p. 541 22. Chapter 40. Endothelial Alterations in Heart Failure: Mechanisms, Molecular Bases, and Therapeutic Implications - p. 551 23. Chapter 41. Endothelial Function in Heart Failure With Preserved Ejection Fraction - p. 561 24. Chapter 42. Endothelium in Cardiomyopathies - p. 569 25. Section IX. Percutaneous Interventions and Transplant - p. S9 26. Chapter 43. Postpercutaneous Interventions: Endothelial Repair - p. 585 27. Chapter 44. Stents and the Endothelium - p. 591 28. Chapter 45. Vascular Disease of the Transplanted Heart: Physiopathology and Therapeutic Options - p. 597 29. Section X. Endothelium and Systemic Diseases - p. S10 30. Chapter 46. Sleep Disorders and Endothelial Dysfunction - p. 615 31. Chapter 47. Smoking and the Endothelium - p. 625 32. Chapter 48. Effects of Radiation on Vascular Endothelium - p. 653 33. Chapter 49. Erectile Dysfunction and the Endothelium - p. 665 34. Chapter 50. Cardiovascular Actions and Therapeutic Implications of Endothelium-Derived Catecholamines - p. 675 35. Chapter 51. Obesity, Endothelium, and Metabolic Syndrome - p. 689 36. Chapter 52. Endothelium in Diabetes - p. 699 37. Chapter 53. Endothelial Mechanisms in Preeclampsia - p. 711 38. Chapter 54. Endothelium and Nitric Oxide: Interactions in Cancer Evolution - p. 721 39. Chapter 55. Corneal Endothelium Cell Dysfunction - p. 735 40. Chapter 56. Connective Tissue and Endothelium - p. 743 41. Chapter 57. Endothelial Alterations in Pulmonary Hypertension - p. 751 42. Chapter 58. Physical Exercise and Endothelium - p. 767 43. Section XI. Overview - p. S11 44. Chapter 59. The Translational Concept in Endothelium—From Research to Clinical Practice - p. 781 45. Index - p. 787
